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Pilot (House)
"Pilot", also known as "Everybody Lies," is the first episode of the medical drama '' House''. The episode premiered on the Fox network on November 16, 2004. It introduces the character of Dr. Gregory House (played by Hugh Laurie)—a maverick antisocial doctor—and his team of diagnosticians at the fictional Princeton-Plainsboro Teaching Hospital in New Jersey. The episode features House's attempts to diagnose a kindergarten teacher after she collapses in class. ''House'' was created by David Shore, who got the idea for the misanthropic title character from a doctor's visit. Initially, producer Bryan Singer wanted an American to play House, but British actor Hugh Laurie's audition convinced him that a foreign actor could play the role. Shore wrote House as a character with parallels to Sherlock Holmes—both are drug users, blunt, and close to being friendless. The show's producers wanted House handicapped in some way and gave the character a damaged leg arising from an impr ...
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House (TV Series)
''House'' (also called ''House, M.D.'') is an American medical drama television series that originally ran on the Fox network for eight seasons, from November 16, 2004, to May 21, 2012. The series' main character is Dr. Gregory House ( Hugh Laurie), an unconventional, misanthropic medical genius who, despite his dependence on pain medication, leads a team of diagnosticians at the fictional Princeton–Plainsboro Teaching Hospital (PPTH) in New Jersey. The series' premise originated with Paul Attanasio, while David Shore, who is credited as creator, was primarily responsible for the conception of the title character. The series' executive producers included Shore, Attanasio, Attanasio's business partner Katie Jacobs, and film director Bryan Singer. It was filmed largely in a neighborhood and business district in Los Angeles County's Westside called Century City. The show received high critical acclaim, and was consistently one of the highest rated series in the United S ...
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Aphasia
Aphasia is an inability to comprehend or formulate language because of damage to specific brain regions. The major causes are stroke and head trauma; prevalence is hard to determine but aphasia due to stroke is estimated to be 0.1–0.4% in the Global North. Aphasia can also be the result of brain tumors, brain infections, or neurodegenerative diseases (such as dementias). To be diagnosed with aphasia, a person's speech or language must be significantly impaired in one (or more) of the four aspects of communication following acquired brain injury. Alternatively, in the case of progressive aphasia, it must have significantly declined over a short period of time. The four aspects of communication are auditory comprehension, verbal expression, reading and writing, and functional communication. The difficulties of people with aphasia can range from occasional trouble finding words, to losing the ability to speak, read, or write; intelligence, however, is unaffected. Expressive l ...
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Vasculitis
Vasculitis is a group of disorders that destroy blood vessels by inflammation. Both arteries and veins are affected. Lymphangitis (inflammation of lymphatic vessels) is sometimes considered a type of vasculitis. Vasculitis is primarily caused by leukocyte migration and resultant damage. Although both occur in vasculitis, inflammation of veins ( phlebitis) or arteries ( arteritis) on their own are separate entities. Signs and symptoms Possible signs and symptoms include: * General symptoms: Fever, unintentional weight loss * Skin: Palpable purpura, livedo reticularis * Muscles and joints: Muscle pain or inflammation, joint pain or joint swelling * Nervous system: Mononeuritis multiplex, headache, stroke, tinnitus, reduced visual acuity, acute visual loss * Heart and arteries: Heart attack, high blood pressure, gangrene * Respiratory tract: Nosebleeds, bloody cough, lung infiltrates * GI tract: Abdominal pain, bloody stool, perforations (hole in the GI tract) * Kid ...
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Asthma
Asthma is a long-term inflammatory disease of the airways of the lungs. It is characterized by variable and recurring symptoms, reversible airflow obstruction, and easily triggered bronchospasms. Symptoms include episodes of wheezing, coughing, chest tightness, and shortness of breath. These may occur a few times a day or a few times per week. Depending on the person, asthma symptoms may become worse at night or with exercise. Asthma is thought to be caused by a combination of genetic and environmental factors. Environmental factors include exposure to air pollution and allergens. Other potential triggers include medications such as aspirin and beta blockers. Diagnosis is usually based on the pattern of symptoms, response to therapy over time, and spirometry lung function testing. Asthma is classified according to the frequency of symptoms, forced expiratory volume in one second (FEV1), and peak expiratory flow rate. It may also be classified as atopic or non-atop ...
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Metered-dose Inhaler
A metered-dose inhaler (MDI) is a device that delivers a specific amount of medication to the lungs, in the form of a short burst of aerosolized medicine that is usually self-administered by the patient via inhalation. It is the most commonly used delivery system for treating asthma, chronic obstructive pulmonary disease (COPD) and other respiratory diseases. The medication in a metered dose inhaler is most commonly a bronchodilator, corticosteroid or a combination of both for the treatment of asthma and COPD. Other medications less commonly used but also administered by MDI are mast cell stabilizers, such as cromoglicate or nedocromil. Description A metered-dose inhaler consists of three major components; the canister which is produced in aluminium or stainless steel by means of deep drawing, where the formulation resides; the metering valve, which allows a metered quantity of the formulation to be dispensed with each actuation; and an actuator (or mouthpiece) which allows t ...
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Niacin (substance)
Niacin, also known as nicotinic acid, is an organic compound and a form of vitamin B3, an essential human nutrient. It can be manufactured by plants and animals from the amino acid tryptophan. Niacin is obtained in the diet from a variety of whole and processed foods, with highest contents in fortified packaged foods, meat, poultry, red fish such as tuna and salmon, lesser amounts in nuts, legumes and seeds. Niacin as a dietary supplement is used to treat pellagra, a disease caused by niacin deficiency. Signs and symptoms of pellagra include skin and mouth lesions, anemia, headaches, and tiredness. Many countries mandate its addition to wheat flour or other food grains, thereby reducing the risk of pellagra. The amide derivative nicotinamide (niacinamide) is a component of the coenzymes nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP+). Although niacin and nicotinamide are identical in their vitamin activity, nicotina ...
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Tracheotomy
Tracheotomy (, ), or tracheostomy, is a surgical airway management procedure which consists of making an incision (cut) on the anterior aspect (front) of the neck and opening a direct airway through an incision in the trachea (windpipe). The resulting stoma (hole) can serve independently as an airway or as a site for a tracheal tube or tracheostomy tube to be inserted; this tube allows a person to breathe without the use of the nose or mouth. Etymology and terminology The etymology of the word ''tracheotomy'' comes from two Greek words: the root ''tom-'' (from Greek τομή ''tomḗ'') meaning "to cut", and the word ''trachea'' (from Greek τραχεία ''tracheía''). The word ''tracheostomy'', including the root ''stom-'' (from Greek στόμα ''stóma'') meaning "mouth," refers to the making of a semi-permanent or permanent opening, and to the opening itself. Some sources offer different definitions of the above terms. Part of the ambiguity is due to the uncertainty ...
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Jennifer Morrison
Jennifer Marie Morrison is an American actress, director, producer, and former child model. She is mainly known for her roles as Dr. Allison Cameron in the medical-drama series ''House'' (2004–2012) and Emma Swan in the ABC adventure-fantasy series '' Once Upon a Time'' (2011–2018). She has also portrayed Zoey Pierson, one of Ted Mosby's love interests, on the comedy series ''How I Met Your Mother'', Winona Kirk, mother of James T. Kirk in the 2009 science-fiction film ''Star Trek'', and Tess Conlon in the 2011 sports drama film ''Warrior''. She made her feature-film directorial debut with ''Sun Dogs'' (2017). Early life Morrison was born in Chicago, Illinois, and grew up in Arlington Heights, Illinois. She is the oldest of three children; her sister, Julia, is a singer-songwriter and music band therapist, and her brother, Daniel, is a high-school band director. Her father, David, is a retired music teacher and high-school band director who was named Teacher of the Year by ...
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Allison Cameron
Allison Cameron, M.D., is a fictional character on the Fox medical drama ''House'', portrayed by American actress Jennifer Morrison. An immunologist, Cameron was a member of Dr. Gregory House's team of handpicked specialists at Princeton-Plainsboro Teaching Hospital's Department of Diagnostic Medicine. She returned for the final episode of the series, " Everybody Dies". Personality At the start of the show, Cameron was the only woman on House's initial diagnostic team. She is known for her honesty, sincerity, idealism and strong ethical center. Even so, she is not out of her depth teasing others, as she does when alone with Chase, telling him that women can have hour-long orgasms (in response to Foreman telling her Chase is interested but shy); but, when Foreman enters, she acts completely deadpan. She is a deist, claiming "I believe in a higher order that's in control of what happens, but not in one anthropomorphic entity called 'God' that's concerned with the everyday ...
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Jesse Spencer
Jesse Gordon Spencer (born 12 February 1979) is an Australian actor and musician. He is best known for his roles as Billy Kennedy on the Australian soap opera ''Neighbours'' (1994–2000, 2005, 2022), Robert Chase on the American medical drama ''House'' (2004–2012) and Captain Matthew Casey on the American drama '' Chicago Fire'' (2012–2021). Early life Spencer was born in Melbourne on 12 February 1979 to Rodney Spencer, a radiologist, and Robyn Spencer, who were founders of the Australians Against Further Immigration political party, and would both later contest the 1998 federal election for One Nation. He is one of four siblings. Spencer has two older brothers: Tarney Spencer, an oculoplastic surgeon, and Luke Spencer, an orthopaedic surgeon. His younger sister, Polly Spencer, is an anaesthetist. Growing up, he attended Canterbury Primary School, Malvern Central School, and the private Scotch College. While there, he auditioned for the long-running soap opera ''Neigh ...
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Robert Chase
Robert Chase, M.D. is a fictional character on the Fox medical drama ''House''. He is portrayed by Jesse Spencer. His character was a part of the team of diagnosticians who worked under Gregory House until the end of the third season when House fires him. However, he resumed work at the hospital as a surgeon, and was re-hired by House in season 6. Robert Chase is the longest-serving member of House's staff. Chase has been attracted to Allison Cameron since season 3 of the show and embarks on a romantic relationship with her in "Human Error." In "Post Mortem," he left the Diagnostic Team after realizing he was in the same position as he was 10 years earlier, unlike all of the other former members of the team. However, in the series finale, he rejoins the hospital as the new Head of Diagnostic Medicine, replacing the (supposedly) dead House. Characterization Chase is Australian and was born around the year 1979. His Czech father, Rowan Chase, was a wealthy and world-renowned ...
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Gadolinium
Gadolinium is a chemical element with the symbol Gd and atomic number 64. Gadolinium is a silvery-white metal when oxidation is removed. It is only slightly malleable and is a ductile rare-earth element. Gadolinium reacts with atmospheric oxygen or moisture slowly to form a black coating. Gadolinium below its Curie point of is ferromagnetic, with an attraction to a magnetic field higher than that of nickel. Above this temperature it is the most paramagnetic element. It is found in nature only in an oxidized form. When separated, it usually has impurities of the other rare-earths because of their similar chemical properties. Gadolinium was discovered in 1880 by Jean Charles de Marignac, who detected its oxide by using spectroscopy. It is named after the mineral gadolinite, one of the minerals in which gadolinium is found, itself named for the Finnish chemist Johan Gadolin. Pure gadolinium was first isolated by the chemist Paul-Émile Lecoq de Boisbaudran around 1886. Gadolin ...
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