Pierre Mollaret
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Pierre Mollaret
Pierre Mollaret (10 July 1898 – 3 December 1987) was a French neurologist who made significant scientific contributions to the study of infectious diseases and neurology. He was born in Auxerre, France. A rare disease characterized by recurrent episodes of aseptic meningitis was discovered by Mollaret and named after him - called Mollaret's meningitis; this disease is typically caused by herpes simplex virus infection of the CNS, and rarely by varicella. He is also credited with the characterization of a neural pathway known as the Guillain-Mollaret triangle or Myoclonic triangle, and the discovery of the causative agent of cat-scratch disease Cat-scratch disease (CSD) or felinosis is an infectious disease that most often results from a scratch or bite of a cat. Symptoms typically include a non-painful bump or blister at the site of injury and painful and swollen lymph nodes. People m .... References French neurologists 1898 births 1987 deaths {{france-med ...
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Auxerre
Auxerre ( , ) is the capital of the Yonne department and the fourth-largest city in Burgundy. Auxerre's population today is about 35,000; the urban area (''aire d'attraction'') comprises roughly 113,000 inhabitants. Residents of Auxerre are referred to as ''Auxerrois''. Auxerre is a commercial and industrial centre, with industries including food production, woodworking and batteries. It is also noted for its production of Burgundy wine, including Chablis. In 1995 Auxerre was named "Town of Art and History". Geography Auxerre lies on the river Yonne and the Canal du Nivernais, about 150 km southeast of Paris and 120 km northwest of Dijon. The A6 autoroute (Paris–Lyon) passes northeast of the city. Auxerre-Saint-Gervais station has rail connections to Dijon, Paris, Corbigny and Avallon. History Auxerre was a flourishing Gallo-Roman centre, then called Autissiodorum, through which passed one of the main roads of the area, the Via Agrippa (1st century AD) which ...
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Neurology
Neurology (from el, wikt:νεῦρον, νεῦρον (neûron), "string, nerve" and the suffix wikt:-logia, -logia, "study of") is the branch of specialty (medicine), medicine dealing with the diagnosis and treatment of all categories of conditions and disease involving the brain, the spinal cord and the peripheral nerves. Neurological practice relies heavily on the field of neuroscience, the scientific study of the nervous system. A neurologist is a physician specializing in neurology and trained to investigate, diagnose and treat neurological disorders. Neurologists treat a myriad of neurologic conditions, including stroke, seizures, movement disorders such as Parkinson's disease, autoimmune neurologic disorders such as multiple sclerosis, headache disorders like migraine and dementias such as Alzheimer's disease. Neurologists may also be involved in clinical research, clinical trials, and basic research, basic or translational research. While neurology is a nonsurgical sp ...
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Infectious Disease
An infection is the invasion of tissues by pathogens, their multiplication, and the reaction of host tissues to the infectious agent and the toxins they produce. An infectious disease, also known as a transmissible disease or communicable disease, is an illness resulting from an infection. Infections can be caused by a wide range of pathogens, most prominently bacteria and viruses. Hosts can fight infections using their immune system. Mammalian hosts react to infections with an innate response, often involving inflammation, followed by an adaptive response. Specific medications used to treat infections include antibiotics, antivirals, antifungals, antiprotozoals, and antihelminthics. Infectious diseases resulted in 9.2 million deaths in 2013 (about 17% of all deaths). The branch of medicine that focuses on infections is referred to as infectious disease. Types Infections are caused by infectious agents (pathogens) including: * Bacteria (e.g. '' Mycobacterium tuberculosis ...
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Neurologist
Neurology (from el, νεῦρον (neûron), "string, nerve" and the suffix -logia, "study of") is the branch of medicine dealing with the diagnosis and treatment of all categories of conditions and disease involving the brain, the spinal cord and the peripheral nerves. Neurological practice relies heavily on the field of neuroscience, the scientific study of the nervous system. A neurologist is a physician specializing in neurology and trained to investigate, diagnose and treat neurological disorders. Neurologists treat a myriad of neurologic conditions, including stroke, seizures, movement disorders such as Parkinson's disease, autoimmune neurologic disorders such as multiple sclerosis, headache disorders like migraine and dementias such as Alzheimer's disease. Neurologists may also be involved in clinical research, clinical trials, and basic or translational research. While neurology is a nonsurgical specialty, its corresponding surgical specialty is neurosurgery. Histor ...
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Mollaret's Meningitis
Mollaret's meningitis is a recurrent or chronic inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges. Since Mollaret's meningitis is a recurrent, benign (non-cancerous), aseptic meningitis, it is also referred to as benign recurrent lymphocytic meningitis. It was named for Pierre Mollaret, the French neurologist who first described it in 1944. Although chronic meningitis has been defined as "irritation and inflammation of the meninges persisting for more than 4 weeks being associated with pleocytosis in the cerebrospinal fluid", cerebrospinal fluid abnormalities may not be detectable for the entire time. Diagnosis can be elusive, as Helbok et al. note: "in reality, many more weeks, even months pass by until the diagnosis is established. In many cases the signs and symptoms of chronic meningitis not only persist for periods longer than 4 weeks, they even progress with continuing deterioration, i. e. headache, neck stiffness ...
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Herpes Simplex Virus
Herpes simplex virus 1 and 2 (HSV-1 and HSV-2), also known by their taxonomical names ''Human alphaherpesvirus 1'' and '' Human alphaherpesvirus 2'', are two members of the human ''Herpesviridae'' family, a set of viruses that produce viral infections in the majority of humans. Both HSV-1 and HSV-2 are very common and contagious. They can be spread when an infected person begins shedding the virus. As of 2016, about 67% of the world population under the age of 50 had HSV-1. In the United States, about 47.8% and 11.9% are estimated to have HSV-1 and HSV-2, respectively, though actual prevalence may be much higher. Because it can be transmitted through any intimate contact, it is one of the most common sexually transmitted infections. Symptoms Many of those who are infected ''never'' develop symptoms. Symptoms, when they occur, may include watery blisters in the skin or mucous membranes of the mouth, lips, nose, genitals, or eyes (herpes simplex keratitis). Lesions heal with a ...
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Myoclonic Triangle
The myoclonic triangle (also known by its eponym Triangle of Guillain-Mollaret or dentato-rubro-olivary pathway) is an important feedback circuit of the brainstem and deep cerebellar nuclei which is responsible for modulating spinal cord motor activity. The circuit is thus composed: # Fibers of the rubro-olivary tract project from the parvocellular red nucleus via the central tegmental tract to the ipsilateral inferior olivary nucleus. # The inferior olivary nucleus sends its afferents via climbing fibers in the inferior cerebellar peduncle to Purkinje cells of the contralateral cerebellar cortex. # The Purkinje cells send their afferents to the ipsilateral dentate nucleus. # Dentatorubral tract fibers: the dentate nucleus afferents travel via the superior cerebellar peduncle to the contralateral red nucleus, thus completing the circuit. Of note, this circuit contains a double decussation, implying that a lesion in this tract ...
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Cat Scratch Fever
''Cat Scratch Fever'' is the third studio album by American rock musician Ted Nugent. It was released on May 13, 1977, by Epic Records. Vocalist Derek St. Holmes, who had left the band during the recording of the album ''Free-for-All'', had come back for touring in 1976 and was again the principal lead singer on this album. A commercial success, the album has been certified multi-platinum by the RIAA. Nugent released his next album, ''Double Live Gonzo!'', the following year. Reception ''Cat Scratch Fever'' received a mostly positive review from Greg Prato of AllMusic, who remarked that it "matched the focused ferocity of Nugent's excellent 1975 debut", proclaiming it a "first-rate set of brash hard rockers". Track listing All songs written by Ted Nugent, except "Live It Up" (written by Nugent and Derek St. Holmes). All songs arranged by Nugent, Rob Grange, St. Holmes, and Cliff Davies. Personnel ;Band members *Derek St. Holmes – rhythm and lead guitar, lead and back ...
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French Neurologists
French (french: français(e), link=no) may refer to: * Something of, from, or related to France ** French language, which originated in France, and its various dialects and accents ** French people, a nation and ethnic group identified with France ** French cuisine, cooking traditions and practices Fortnite French places Arts and media * The French (band), a British rock band * "French" (episode), a live-action episode of ''The Super Mario Bros. Super Show!'' * ''Française'' (film), 2008 * French Stewart (born 1964), American actor Other uses * French (surname), a surname (including a list of people with the name) * French (tunic), a particular type of military jacket or tunic used in the Russian Empire and Soviet Union * French's, an American brand of mustard condiment * French catheter scale, a unit of measurement of diameter * French Defence, a chess opening * French kiss, a type of kiss involving the tongue See also * France (other) * Franch, a surname * French ...
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1898 Births
Events January–March * January 1 – New York City annexes land from surrounding counties, creating the City of Greater New York as the world's second largest. The city is geographically divided into five boroughs: Manhattan, Brooklyn, Queens, The Bronx and Staten Island. * January 13 – Novelist Émile Zola's open letter to the President of the French Republic on the Dreyfus affair, ''J'Accuse…!'', is published on the front page of the Paris daily newspaper ''L'Aurore'', accusing the government of wrongfully imprisoning Alfred Dreyfus and of antisemitism. * February 12 – The automobile belonging to Henry Lindfield of Brighton rolls out of control down a hill in Purley, London, England, and hits a tree; thus he becomes the world's first fatality from an automobile accident on a public highway. * February 15 – Spanish–American War: The USS ''Maine'' explodes and sinks in Havana Harbor, Cuba, for reasons never fully established, killing 266 ...
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