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Piceid
Piceid is a stilbenoid glucoside and is a major resveratrol derivative in grape juices. It can be found in the bark of ''Picea sitchensis''. It can also be isolated from ''Reynoutria japonica'' ( syn. ''Fallopia japonica''), the Japanese knotweed (syn. ''Polygonum cuspidatum''). Resveratrol can be produced from piceid via the mold ''Aspergillus oryzae''. as the fungus produces a potent beta-glucosidase. ''trans''-Piceid is the glucoside formed with ''trans''-resveratrol, while ''cis''-piceid is formed with ''cis''-resveratrol. ''trans''-Resveratrol-3-''O''-glucuronide is one of the two metabolites of ''trans''-piceid in rat. Resveratrol glucoside from transgenic alfalfa prevents aberrant crypt foci in mice.R See also * Resveratroloside Resveratroloside is a stilbenoid glucoside. It can be found in ''Paeonia lactiflora ''Paeonia lactiflora'' (Chinese peony, Chinese herbaceous peony, or common garden peony) is a species of herbaceous perennial flowering plant in the fami ...
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Resveratrol
Resveratrol (3,5,4′-trihydroxy-''trans''-stilbene) is a stilbenoid, a type of natural phenol, and a phytoalexin produced by several plants in response to injury or when the plant is under attack by pathogens, such as bacteria or fungi. Sources of resveratrol in food include the skin of grapes, blueberries, raspberries, mulberries, and peanuts. Although commonly used as a dietary supplement and studied in laboratory models of human diseases, there is no high-quality evidence that resveratrol improves lifespan or has a substantial effect on any human disease. Research Resveratrol has been studied for its potential therapeutic use, with little evidence of anti-disease effects or health benefits in humans. Cardiovascular disease There is no evidence of benefit from resveratrol in people who already have heart disease. A 2018 meta-analysis found no effect on systolic or diastolic blood pressure; a sub-analysis revealed a 2 mmHg decrease in systolic pressure only from res ...
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Resveratrol
Resveratrol (3,5,4′-trihydroxy-''trans''-stilbene) is a stilbenoid, a type of natural phenol, and a phytoalexin produced by several plants in response to injury or when the plant is under attack by pathogens, such as bacteria or fungi. Sources of resveratrol in food include the skin of grapes, blueberries, raspberries, mulberries, and peanuts. Although commonly used as a dietary supplement and studied in laboratory models of human diseases, there is no high-quality evidence that resveratrol improves lifespan or has a substantial effect on any human disease. Research Resveratrol has been studied for its potential therapeutic use, with little evidence of anti-disease effects or health benefits in humans. Cardiovascular disease There is no evidence of benefit from resveratrol in people who already have heart disease. A 2018 meta-analysis found no effect on systolic or diastolic blood pressure; a sub-analysis revealed a 2 mmHg decrease in systolic pressure only from res ...
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Stilbenoid
Stilbenoids are hydroxylated derivatives of stilbene. They have a C6–C2–C6 structure. In biochemical terms, they belong to the family of phenylpropanoids and share most of their biosynthesis pathway with chalcones. Most stilbenoids are produced by plants, and the only known exception is the antihelminthic and antimicrobial stilbenoid, 2-isopropyl-5- ''E'')-2-phenylvinylenzene-1,3-diol, biosynthesized by the Gram-negative bacterium '' Photorhabdus luminescens.'' Chemistry Stilbenoids are hydroxylated derivatives of stilbene and have a C6–C2–C6 structure. They belong to the family of phenylpropanoids and share most of their biosynthesis pathway with chalcones. Under UV irradiation, stilbene and its derivatives undergo intramolecular cyclization, called stilbene photocyclization to form dihydrophenanthrenes. Oligomeric forms are known as oligostilbenoids. Types ;Aglycones * Piceatannol in the roots of Norway spruces * Pinosylvin is a fungal toxin protecting wood f ...
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Glucoside
A glucoside is a glycoside that is derived from glucose. Glucosides are common in plants, but rare in animals. Glucose is produced when a glucoside is hydrolysed by purely chemical means, or decomposed by fermentation or enzymes. The name was originally given to plant products of this nature, in which the other part of the molecule was, in the greater number of cases, an aromatic aldehydic or phenolic compound (exceptions are Jinigrin and Jalapin or Scammonin). It has now been extended to include synthetic ethers, such as those obtained by acting on alcoholic glucose solutions with hydrochloric acid, and also the polysaccharoses, e.g. cane sugar, which appear to be ethers also. Although glucose is the most common sugar present in glucosides, many are known which yield rhamnose or iso-dulcite; these may be termed pentosides. Much attention has been given to the non-sugar parts (aglyca) of the molecules; the constitutions of many have been determined, and the compounds synthesi ...
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Picea Sitchensis
''Picea sitchensis'', the Sitka spruce, is a large, coniferous, evergreen tree growing to almost tall, with a trunk diameter at breast height that can exceed 5 m (16 ft). It is by far the largest species of spruce and the fifth-largest conifer in the world (behind giant sequoia, coast redwood, kauri, and western red cedar), and the third-tallest conifer species (after coast redwood and coast Douglas fir). The Sitka spruce is one of the few species documented to exceed in height. Its name is derived from the community of Sitka in southeast Alaska, where it is prevalent. Its range hugs the western coast of Canada and the US, continuing south into northernmost California. Description The bark is thin and scaly, flaking off in small, circular plates across. The inner bark is reddish-brown. The crown is broad conic in young trees, becoming cylindric in older trees; old trees may not have branches lower than . The shoots are very pale buff-brown, almost white, and glab ...
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Reynoutria Japonica
''Reynoutria japonica'', synonyms ''Fallopia japonica'' and ''Polygonum cuspidatum'', is a species of herbaceous perennial plant in the knotweed and buckwheat family Polygonaceae. Common names include Japanese knotweed and Asian knotweed. It is native to East Asia in Japan, China and Korea. In North America and Europe, the species has successfully established itself in numerous habitats, and is classified as a pest and invasive species in several countries. Japanese knotweed has hollow stems with distinct raised nodes that give it the appearance of bamboo, though it is not related. While stems may reach a maximum height of each growing season, it is typical to see much smaller plants in places where they sprout through cracks in the pavement or are repeatedly cut down. The leaves are broad oval with a truncated base, long and broad, with an entire margin. The flowers are small, cream or white, produced in erect racemes long in late summer and early autumn. Related species ...
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Synonym (taxonomy)
The Botanical and Zoological Codes of nomenclature treat the concept of synonymy differently. * In botanical nomenclature, a synonym is a scientific name that applies to a taxon that (now) goes by a different scientific name. For example, Linnaeus was the first to give a scientific name (under the currently used system of scientific nomenclature) to the Norway spruce, which he called ''Pinus abies''. This name is no longer in use, so it is now a synonym of the current scientific name, ''Picea abies''. * In zoology, moving a species from one genus to another results in a different binomen, but the name is considered an alternative combination rather than a synonym. The concept of synonymy in zoology is reserved for two names at the same rank that refers to a taxon at that rank - for example, the name ''Papilio prorsa'' Linnaeus, 1758 is a junior synonym of ''Papilio levana'' Linnaeus, 1758, being names for different seasonal forms of the species now referred to as ''Araschnia le ...
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Aspergillus Oryzae
''Aspergillus oryzae'', also known as , is a filamentous fungus (a mold) used in East Asia to saccharify rice, sweet potato, and barley in the making of alcoholic beverages such as ''sake'' and '' shōchū'', and also to ferment soybeans for making soy sauce and ''miso''. However, in the production of fermented foods of soybeans such as soy sauce and ''miso'', '' Aspergillus sojae'' is sometimes used instead of ''A. oryzae''. Incidentally, in China and Korea, the fungi used for fermented foods for a long time in the production of traditional alcoholic beverages were not ''A. oryzae'' but fungi belonging to ''Rhizopus'' and ''Mucor''. '' A. oryzae'' is also used for the production of rice vinegars. Barley ''kōji'' (麦麹) or rice ''kōji'' (米麹) are made by fermenting the grains with ''A. oryzae'' hyphae. Genomic analysis has led some scholars to believe that the Japanese domesticated the ''Aspergillus flavus'' that had mutated and ceased to produce toxic aflatoxins, givi ...
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Beta-glucosidase
β-Glucosidase (EC 3.2.1.21; systematic name β-D-glucoside glucohydrolase) is an enzyme that catalyses the following reaction: : Hydrolysis of terminal, non-reducing β-D-glucosyl residues with release of β-D-glucose Structure β-Glucosidase is composed of two polypeptide chains. Each chain is made up of 438 amino acids and constitute a subunit of the enzyme. Each of these subunits contains an active site. The active site has three potential components: the pocket, the cleft, and the tunnel. The pocket structure is beneficial for recognition of monosaccharide like glucose. The cleft allows for binding of sugars to form polysaccharides. The tunnel allows for the enzyme to attach to polysaccharide and then release product while still attached to the sugar. Function The function of the enzyme is to perform hydrolysis of various glycosides and oligosaccharides. The most significant oligosaccharide β-glucosidase reacts with is cellulose. Cellulose is a polymer composed of β-1 ...
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Trans-Resveratrol-3-O-glucuronide
''trans''-Resveratrol-3-''O''-glucuronide is a metabolite of resveratrol and trans-resveratrol-3-O-glucoside (piceid). References Resveratrol glycosides Glucuronide esters Phenol glucuronides Phenolic human metabolites {{aromatic-stub ...
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Aberrant Crypt Foci
Aberrant crypt foci (ACF) are clusters of abnormal tube-like glands in the lining of the colon and rectum. Aberrant crypt foci form before colorectal polyps and are one of the earliest changes seen in the colon that may lead to cancer. ACF are, as opposed to normal epithelial cells, apoptosis resistant. When looking for aberrant crypt foci with microscopy, methylene blue is used as a staining agent. The resulting figure is fairly easy to detect under the microscope at low magnification (x40). Chemically induced ACF in rodents have been used extensively to test chemicals and diets that might prevent colorectal cancer, and reported in more than 400 scientific articles. The "chemoprevention database" shows the results of all published scientific studies of chemopreventive agents, in people and in animals. The relevance of ACF as a surrogate endpoint biomarker for cancer is controversial. Recently, several alternative precancerous lesions have been described (namely MDF, BCAC, and fl ...
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Resveratroloside
Resveratroloside is a stilbenoid glucoside. It can be found in ''Paeonia lactiflora ''Paeonia lactiflora'' (Chinese peony, Chinese herbaceous peony, or common garden peony) is a species of herbaceous perennial flowering plant in the family Paeoniaceae, native to central and eastern Asia from eastern Tibet across northern Chi ...''. References External links Resveratroloside at kanaya.naist.jp Resveratrol glycosides Phenol glucosides {{aromatic-stub ...
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