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Pharmaceutical Packaging
Pharmaceutical packaging (or drug packaging) is the packages and the packaging processes for pharmaceutical preparations. It involves all of the operations from production through drug distribution channels to the end consumer. Pharmaceutical packaging is highly regulated but with some variation in the details, depending on the country of origin or the region. Several common factors can include: assurance of patient safety, assurance of the efficacy of the drug through the intended shelf life, uniformity of the drug through different production lots, thorough documentation of all materials and processes, control of possible migration of packaging components into the drug, control of degradation of the drug by oxygen, moisture, heat, etc., prevention of microbial contamination, sterility, etc. Packaging is often involved in dispensing, dosing, and use of the pharmaceutical product. Communication of proper use and cautionary labels are also regulated. Packaging is an integr ...
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Risperdal Tablets
Risperidone, sold under the brand name Risperdal among others, is an atypical antipsychotic used to treat schizophrenia and bipolar disorder. It is taken either by mouth or by injection (subcutaneous or intramuscular). The injectable versions are long-acting and last for 2–4 weeks. Common side effects include movement problems, sleepiness, dizziness, trouble seeing, constipation, and increased weight. Serious side effects may include the potentially permanent movement disorder tardive dyskinesia, as well as neuroleptic malignant syndrome, an increased risk of suicide, and high blood sugar levels. In older people with psychosis as a result of dementia, it may increase the risk of death. It is unknown if it is safe for use in pregnancy. Its mechanism of action is not entirely clear, but is believed to be related to its action as a dopamine and serotonin antagonist. Study of risperidone began in the late 1980s and it was approved for sale in the United States in 1993. It ...
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Homeopathic
Homeopathy or homoeopathy is a pseudoscientific system of alternative medicine. It was conceived in 1796 by the German physician Samuel Hahnemann. Its practitioners, called homeopaths, believe that a substance that causes symptoms of a disease in healthy people can cure similar symptoms in sick people; this doctrine is called '' similia similibus curentur'', or "like cures like". Homeopathic preparations are termed ''remedies'' and are made using homeopathic dilution. In this process, the selected substance is repeatedly diluted until the final product is chemically indistinguishable from the diluent. Often not even a single molecule of the original substance can be expected to remain in the product. Between each dilution homeopaths may hit and/or shake the product, claiming this makes the diluent remember the original substance after its removal. Practitioners claim that such preparations, upon oral intake, can treat or cure disease. All relevant scientific knowledge abo ...
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National Institute Of Health
The National Institutes of Health, commonly referred to as NIH (with each letter pronounced individually), is the primary agency of the United States government responsible for biomedical and public health research. It was founded in the late 1880s and is now part of the United States Department of Health and Human Services. The majority of NIH facilities are located in Bethesda, Maryland, and other nearby suburbs of the Washington metropolitan area, with other primary facilities in the Research Triangle Park in North Carolina and smaller satellite facilities located around the United States. The NIH conducts its own scientific research through the NIH Intramural Research Program (IRP) and provides major biomedical research funding to non-NIH research facilities through its Extramural Research Program. , the IRP had 1,200 principal investigators and more than 4,000 postdoctoral fellows in basic, translational, and clinical research, being the largest biomedical research institu ...
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Society For Historical Archaeology
The Society for Historical Archaeology (SHA) is a professional organization of scholars concerned with the archaeology of the modern world (15th century-present). Founded in 1967, the SHA promotes scholarly research and the dissemination of knowledge pertaining to historical archaeology. The society is specifically interested in the identification, excavation, interpretation, and conservation of sites and materials on land and underwater. It is the largest such organization in the world and the third largest anthropological organization in the United States. Mission According to its Constitution, :The Society for Historical Archaeology shall be an educational not-for-profit organization to promote scholarly research and the dissemination of knowledge concerning historical archaeology; to exchange information in this field; to hold periodic conferences to discuss problems of mutual interest relating to the study of historical archaeology; and to obtain the cooperation of the conc ...
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Induction Sealed Bottle
Induction, Inducible or Inductive may refer to: Biology and medicine * Labor induction (birth/pregnancy) * Induction chemotherapy, in medicine * Induced stem cells, stem cells derived from somatic, reproductive, pluripotent or other cell types by deliberate epigenetic reprogramming * Cellular differentiation, the process where a cell changes from one cell type to another * Enzyme induction and inhibition, a process in which a molecule induces the expression of an enzyme * Morphogenesis, the biological process that causes an organism to develop its shape * Regulation of gene expression, the means by which a gene product is either induced or inhibited Chemistry * Induction period, the time interval between cause and measurable effect * Inductive cleavage, in organic chemistry * Inductive effect, the redistribution of electron density through molecular sigma bonds * Asymmetric induction, the formation of one specific stereoisomer in the presence of a nearby chiral center ...
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Plastic Film
Plastic film is a thin continuous polymeric material. Thicker plastic material is often called a "sheet". These thin plastic membranes are used to separate areas or volumes, to hold items, to act as barriers, or as printable surfaces. Plastic films are used in a wide variety of applications. These include: packaging, plastic bags, labels, building construction, landscaping, electrical fabrication, photographic film, film stock for movies, video tape, etc. Materials Almost all plastics can be formed into a thin film. Some of the primary ones are: * Polyethylene – The most common plastic film is made of one of the varieties of polyethylene: low-density polyethylene, medium-density polyethylene, high-density polyethylene, or linear low-density polyethylene. * Polypropylene – Polypropylene can be made a cast film, biaxially oriented film (BOPP), or as a uniaxially oriented film. * Polyester – BoPET is a biaxially oriented polyester film. * Nylon – BOPA/BON ...
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Aluminum Foil
Aluminium foil (or aluminum foil in North American English; often informally called tin foil) is aluminium prepared in thin metal leaves with a thickness less than ; thinner gauges down to are also commonly used. Standard household foil is typically thick, and heavy duty household foil is typically . The foil is pliable, and can be readily bent or wrapped around objects. Thin foils are fragile and are sometimes laminated with other materials such as plastics or paper to make them stronger and more useful. Annual production of aluminium foil was approximately in Europe and in the U.S."Foil & Packaging"
. The Aluminum Association (USA).
in 2003. Approximately 75% of aluminium foil is used for
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Paperboard
Paperboard is a thick paper-based material. While there is no rigid differentiation between paper and paperboard, paperboard is generally thicker (usually over 0.30 mm, 0.012 in, or 12 points) than paper and has certain superior attributes such as foldability and rigidity. According to ISO standards, paperboard is a paper with a grammage above 250 g/m2, but there are exceptions. Paperboard can be single- or multi-ply. Paperboard can be easily cut and formed, is lightweight, and because it is strong, is used in packaging. Another end-use is high quality graphic printing, such as book and magazine covers or postcards. Paperboard is also used in fine arts for creating sculptures. Sometimes it is referred to as ''cardboard'', which is a generic, lay term used to refer to any heavy paper pulp–based board, however this usage is deprecated in the paper, printing and packaging industries as it does not adequately describe each product type. History In 1817, the first paperbo ...
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Tablet (pharmacy)
A tablet (also known as a pill) is a pharmaceutical oral dosage form (''oral solid dosage'', or OSD) or solid unit dosage form. Tablets may be defined as the solid unit dosage form of medication with suitable excipients. It comprises a mixture of active substances and excipients, usually in powder form, that are pressed or compacted into a solid dose. The main advantages of tablets are that they ensure a consistent dose of medicine that is easy to consume. Tablets are prepared either by moulding or by compression. The excipients can include diluents, binders or granulating agents, glidants (flow aids) and lubricants to ensure efficient tabletting; disintegrants to promote tablet break-up in the digestive tract; sweeteners or flavours to enhance taste; and pigments to make the tablets visually attractive or aid in visual identification of an unknown tablet. A polymer coating is often applied to make the tablet smoother and easier to swallow, to control the release rate of t ...
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Suppositories
A suppository is a dosage form used to deliver medications by insertion into a body orifice where it dissolves or melts to exert local or systemic effects. There are three types of suppositories, each to insert into a different sections: rectal suppositories into the rectum, vaginal suppositories into the vagina, and urethral suppositories into the urethra of a male. Suppositories are ideal for infants, elderly individuals and post-operative patients, who are unable to swallow oral medications, and for individuals experiencing severe nausea and/or vomiting. Composition Several different ingredients can be used to form the base of a suppository: cocoa butter or a similar substitute, polyethylene glycol, hydrogels, and glycerinated gelatin. The type of material used depends on the type of suppository, the type of drug, and the conditions in which the suppository will be stored. Rectal suppositories In 1991, a study on suppository insertion in ''The Lancet'' found that the "torp ...
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Capsule (pharmacy)
In the manufacture of pharmaceuticals, encapsulation refers to a range of dosage forms—techniques used to enclose medicines—in a relatively stable shell known as a capsule, allowing them to, for example, be taken orally or be used as suppositories. The two main types of capsules are: * Hard-shelled capsules, which contain dry, powdered ingredients or miniature pellets made by ''e.g.'' processes of extrusion or spheronization. These are made in two-halves: a smaller-diameter “body” that is filled and then sealed using a larger-diameter “cap”. * Soft-shelled capsules, primarily used for oils and for active ingredients that are dissolved or suspended in oil. Both of these classes of capsules are made from aqueous solutions of gelling agents, such as animal protein (mainly gelatin) or plant polysaccharides or their derivatives (such as carrageenans and modified forms of starch and cellulose). Other ingredients can be added to the gelling agent solution including plastici ...
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Unit Dose
Dosage forms (also called unit doses) are pharmaceutical drug products in the form in which they are marketed for use, with a specific mixture of active ingredients and inactive components (excipients), in a particular configuration (such as a capsule shell, for example), and apportioned into a particular dose. For example, two products may both be amoxicillin, but one is in 500 mg capsules and another is in 250 mg chewable tablets. The term unit dose can also sometimes encompass non-reusable ''packaging'' as well (especially when each drug product is individually packaged), although the FDA distinguishes that by ''unit-dose "packaging" or "dispensing"''. Depending on the context, ''multi(ple) unit dose'' can refer to distinct drug products ''packaged'' together, or to a ''single'' drug product containing multiple drugs and/or doses. The term dosage form can also sometimes refer ''only'' to the pharmaceutical formulation of a drug product's constituent drug substance(s) and any blen ...
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