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Petrus Johannes Waardenburg
Petrus Johannes Waardenburg (3 June 1886, Nijeveen, Drenthe – 23 September 1979) was a Dutch ophthalmologist, geneticist, and pioneer in the application of genetics to ophthalmology. Waardenburg syndrome is named after him. Biography Waardenburg studied medicine at the Utrecht University from 1904–11, and then trained in ophthalmology before receiving an MD for a dissertation on the hereditary basis of the physiological and pathological characteristics of the eye in 1913. Waardenburg was a regular contributor to eugenics publications. In 1932 Waardenburg suggested that Down syndrome might be the consequence of a chromosomal aberration, a fact which was confirmed after 27 years, by Jérôme Lejeune and his colleagues. From 1934 to 1940, Waardenburg was external university lecturer in medical genetics at Utrecht University. From 1931 to 1935 he was secretary of the Netherlands Ophthalmological Society. He was a founding member of the Netherlands Anthropogenetic Society a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nijeveen
Nijeveen is a village in the Dutch province of Drenthe. It is a part of the municipality of Meppel, and lies about 5 km northwest of Meppel. History The village was first mentioned in 1310 as "in Hesselrevene", and means "new bog". Nijeveen is a road village which started as a peat excavation settlement. In 1477, a piece of land was purchased by the farmers in the centre of the hamlet to built a church and clergy house. The church was enlarged in 1627 and the 18th century. The tower dates shortly after 1477, but has a date of 1683 when it is probably restored or rebuilt. Nijeveen was home to 390 people in 1840. Since 1976 there is a German windmill named De Sterrenberg which has a cap winded by a fantail. Nijeveen was a separate municipality until 1998, when it was amalgamated with Meppel Meppel (; Drents: ''Möppelt'') is a city and municipality in the Northeastern Netherlands. It constitutes the southwestern part of the province of Drenthe. Meppel is the smallest mun ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
David Klein (ophthalmologist)
David Klein (1908 – 1993) was a Swiss human geneticist and ophthalmologist. Klein graduating from the University of Basel in 1934. After graduating, he worked at the Rheinau Psychiatric Clinic, Zurich. He moved to Geneva as scientific assistant to professor Adolphe Franceschetti at the ophthalmological clinic. In 1970 he was appointed full professor. He retired in 1978 with the status of professor emeritus. After retirement, he was active as consultant in human genetics at the ophthalmological clinic, Geneva, and the school of amblyopic and blind children in Baar, Switzerland. Klein made important contributions towards the understanding of Waardenburg syndrome, or more fully, the "van der Hoeve-Halbertsma-Waardenburg-Klein syndrome". In August 1947 Klein presented a deaf mute child, who was 10 years of age, and had partial albinism of the hair and body, blue hypoplastic irides, blepharophimosis Blepharophimosis is a congenital anomaly in which the eyelids are underdeve ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dutch Ophthalmologists
Dutch commonly refers to: * Something of, from, or related to the Netherlands * Dutch people () * Dutch language () Dutch may also refer to: Places * Dutch, West Virginia, a community in the United States * Pennsylvania Dutch Country People Ethnic groups * Germanic peoples, the original meaning of the term ''Dutch'' in English ** Pennsylvania Dutch, a group of early Germanic immigrants to Pennsylvania *Dutch people, the Germanic group native to the Netherlands Specific people * Dutch (nickname), a list of people * Johnny Dutch (born 1989), American hurdler * Dutch Schultz (1902–1935), American mobster born Arthur Simon Flegenheimer * Dutch Mantel, ring name of American retired professional wrestler Wayne Maurice Keown (born 1949) * Dutch Savage, ring name of professional wrestler and promoter Frank Stewart (1935–2013) Arts, entertainment, and media Fictional characters * Dutch (''Black Lagoon''), an African-American character from the Japanese manga and anime ''Black L ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dutch Geneticists
Dutch commonly refers to: * Something of, from, or related to the Netherlands * Dutch people () * Dutch language () Dutch may also refer to: Places * Dutch, West Virginia, a community in the United States * Pennsylvania Dutch Country People Ethnic groups * Germanic peoples, the original meaning of the term ''Dutch'' in English ** Pennsylvania Dutch, a group of early Germanic immigrants to Pennsylvania *Dutch people, the Germanic group native to the Netherlands Specific people * Dutch (nickname), a list of people * Johnny Dutch (born 1989), American hurdler * Dutch Schultz (1902–1935), American mobster born Arthur Simon Flegenheimer * Dutch Mantel, ring name of American retired professional wrestler Wayne Maurice Keown (born 1949) * Dutch Savage, ring name of professional wrestler and promoter Frank Stewart (1935–2013) Arts, entertainment, and media Fictional characters * Dutch (''Black Lagoon''), an African-American character from the Japanese manga and anime ''Black L ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
People From Meppel
A person ( : people) is a being that has certain capacities or attributes such as reason, morality, consciousness or self-consciousness, and being a part of a culturally established form of social relations such as kinship, ownership of property, or legal responsibility. The defining features of personhood and, consequently, what makes a person count as a person, differ widely among cultures and contexts. In addition to the question of personhood, of what makes a being count as a person to begin with, there are further questions about personal identity and self: both about what makes any particular person that particular person instead of another, and about what makes a person at one time the same person as they were or will be at another time despite any intervening changes. The plural form "people" is often used to refer to an entire nation or ethnic group (as in "a people"), and this was the original meaning of the word; it subsequently acquired its use as a plural form of per ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1979 Deaths
Events January * January 1 ** United Nations Secretary-General Kurt Waldheim heralds the start of the ''International Year of the Child''. Many musicians donate to the ''Music for UNICEF Concert'' fund, among them ABBA, who write the song ''Chiquitita'' to commemorate the event. ** The United States and the People's Republic of China establish full Sino-American relations, diplomatic relations. ** Following a deal agreed during 1978, France, French carmaker Peugeot completes a takeover of American manufacturer Chrysler's Chrysler Europe, European operations, which are based in United Kingdom, Britain's former Rootes Group factories, as well as the former Simca factories in France. * January 7 – Cambodian–Vietnamese War: The People's Army of Vietnam and Vietnamese-backed Kampuchean United Front for National Salvation, Cambodian insurgents announce the fall of Phnom Penh, Cambodia, and the collapse of the Pol Pot regime. Pol Pot and the Khmer Rouge retreat west to an area ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1886 Births
Events January–March * January 1 – Upper Burma is formally annexed to British Burma, following its conquest in the Third Anglo-Burmese War of November 1885. * January 5– 9 – Robert Louis Stevenson's novella ''Strange Case of Dr Jekyll and Mr Hyde'' is published in New York and London. * January 16 – A resolution is passed in the German Parliament to condemn the Prussian deportations, the politically motivated mass expulsion of ethnic Poles and Jews from Prussia, initiated by Otto von Bismarck. * January 18 – Modern field hockey is born with the formation of The Hockey Association in England. * January 29 – Karl Benz patents the first successful gasoline-driven automobile, the Benz Patent-Motorwagen (built in 1885). * February 6– 9 – Seattle riot of 1886: Anti-Chinese sentiments result in riots in Seattle, Washington. * February 8 – The West End Riots following a popular meeting in Trafalgar Square, London. * F ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Order Of The Netherlands Lion
The Order of the Netherlands Lion, also known as the Order of the Lion of the Netherlands ( nl, De Orde van de Nederlandse Leeuw, french: L'Ordre du Lion Néerlandais) is a Dutch order of chivalry founded by King William I of the Netherlands on 29 September 1815. The Order of the Netherlands Lion was until recently awarded to eminent individuals from all walks of life, including generals, ministers of the crown, mayors of large towns, professors and leading scientists, industrialists, high-ranking civil servants, presiding judges and renowned artists. Since 1980 the Order has been primarily used to recognise merit in the arts, science, sport and literature; others are awarded the Order of Orange-Nassau. Appointment to the grade of Commander (see below) is very rare (Nobel Prizewinners; the conductor Bernard Haitink towards the end of his life, and the dancer and choreographer Hans van Manen, for example). The Order ranks after the Military William Order, which is only awarded for ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jan Van Der Hoeve
Jan van der Hoeve (13 April 1878 in Santpoort – 26 April 1952 in Leiden) was a Dutch ophthalmologist. He is recognised for his concept of the phakomatoses, often called neurocutaneous syndromes. Van der Hoeve graduated from the University of Leiden and received his doctorate at the University of Bern. He became a professor of ophthalmology at the University of Groningen and later at the University of Leiden. Van der Hoeve became a member of the Royal Netherlands Academy of Arts and Sciences in 1923. He was elected president of the Physical Section of the institute in 1932. Van der Hoeve made one of the earliest descriptions of Waardenburg syndrome, in 1916. Papers * See also *Timeline of tuberous sclerosis The history of tuberous sclerosis (TSC) research spans less than 200 years. TSC is a rare, multi-system genetic disease that can cause benign tumours to grow on the brain or other vital organs such as the kidneys, heart, eyes, lungs, and skin. A ... References * ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Drenthe
Drenthe () is a province of the Netherlands located in the northeastern part of the country. It is bordered by Overijssel to the south, Friesland to the west, Groningen to the north, and the German state of Lower Saxony to the east. As of November 2019, Drenthe had a population of 493,449 and a total area of . Drenthe has been populated for 15,000 years. The region has subsequently been part of the Episcopal principality of Utrecht, Habsburg Netherlands, Dutch Republic, Batavian Republic, Kingdom of Holland and Kingdom of the Netherlands. Drenthe has been an official province since 1796. The capital and seat of the provincial government is Assen. The King's Commissioner of Drenthe is Jetta Klijnsma. The Labour Party (PvdA) is the largest party in the States-Provincial, followed by the People's Party for Freedom and Democracy (VVD) and the Christian Democratic Appeal (CDA). Drenthe is a sparsely populated rural area, unlike many other parts of the Netherlands; except for t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genetic Disorder
A genetic disorder is a health problem caused by one or more abnormalities in the genome. It can be caused by a mutation in a single gene (monogenic) or multiple genes (polygenic) or by a chromosomal abnormality. Although polygenic disorders are the most common, the term is mostly used when discussing disorders with a single genetic cause, either in a gene or chromosome. The mutation responsible can occur spontaneously before embryonic development (a ''de novo'' mutation), or it can be Heredity, inherited from two parents who are carriers of a faulty gene (autosomal recessive inheritance) or from a parent with the disorder (autosomal dominant inheritance). When the genetic disorder is inherited from one or both parents, it is also classified as a hereditary disease. Some disorders are caused by a mutation on the X chromosome and have X-linked inheritance. Very few disorders are inherited on the Y linkage, Y chromosome or Mitochondrial disease#Causes, mitochondrial DNA (due to t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jérôme Lejeune
Jérôme Jean Louis Marie Lejeune (13 June 1926 – 3 April 1994) was a French pediatrician and geneticist, best known for discovering the link of diseases to chromosome abnormalities, most especially the link between Down Syndrome and trisomy-21 and cri du chat syndrome, amongst several others, and for his subsequent strong opposition to, in his opinion, the improper and immoral use of amniocentesis prenatal testing for eugenic purposes through selective and elective abortion. He is venerated in the Catholic Church, having been declared Venerable by Pope Francis on 21 January 2021. Career Discovering trisomy 21 In 1958, while working in Raymond Turpin’s laboratory with Marthe Gautier, Jérôme Lejeune reported that he had discovered that Down syndrome was caused by an extra copy of chromosome 21. According to Lejeune's laboratory notebooks, he made the observation demonstrating the link on 22 May 1958. The discovery was published by the French Academy of Sciences with Lejeu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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