Peter Charles Doherty
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Peter Charles Doherty
Peter Charles Doherty (born 15 October 1940) is an Australian immunology, immunologist and Nobel laureate. He received the Albert Lasker Award for Basic Medical Research in 1995, the Nobel Prize in Physiology or Medicine jointly with Rolf M. Zinkernagel in 1996 and was named Australian of the Year in 1997. In the Australia Day Honours of 1997, he was named a Companion of the Order of Australia for his work with Zinkernagel. He is also a National Trust Australian Living Treasures, Australian Living Treasure. In 2009 as part of the Q150 celebrations, Doherty's immune system research was announced as one of the Q150 Icons of Queensland for its role as an iconic "innovation and invention". Early life and education Peter Charles Doherty was born in the Brisbane suburb of Sherwood, Queensland, Sherwood on 15 October 1940, to Eric Charles Doherty and Linda Doherty (née Byford). He grew up in Oxley, Queensland, Oxley, and attended Indooroopilly State High School (which now has a le ...
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Brisbane
Brisbane ( ) is the capital and most populous city of the states and territories of Australia, Australian state of Queensland, and the list of cities in Australia by population, third-most populous city in Australia and Oceania, with a population of approximately 2.6 million. Brisbane lies at the centre of the South East Queensland metropolitan region, which encompasses a population of around 3.8 million. The Brisbane central business district is situated within a peninsula of the Brisbane River about from its mouth at Moreton Bay, a bay of the Coral Sea. Brisbane is located in the hilly floodplain of the Brisbane River Valley between Moreton Bay and the Taylor Range, Taylor and D'Aguilar Range, D'Aguilar mountain ranges. It sprawls across several local government in Australia, local government areas, most centrally the City of Brisbane, Australia's most populous local government area. The demonym of Brisbane is ''Brisbanite''. The Traditional Owners of the Brisbane a ...
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Order Of Australia
The Order of Australia is an honour that recognises Australian citizens and other persons for outstanding achievement and service. It was established on 14 February 1975 by Elizabeth II, Queen of Australia, on the advice of the Australian Government. Before the establishment of the order, Australian citizens received British honours. The Monarch of Australia is sovereign head of the order, while the Governor-General of Australia is the principal companion/dame/knight (as relevant at the time) and chancellor of the order. The governor-general's official secretary, Paul Singer (appointed August 2018), is secretary of the order. Appointments are made by the governor-general on behalf of the Monarch of Australia, based on recommendations made by the Council of the Order of Australia. Recent knighthoods and damehoods were recommended to the governor-general by the Prime Minister of Australia. Levels of membership The order is divided into a general and a military division. ...
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Meningitis Viruses
Viral meningitis, also known as aseptic meningitis, is a type of meningitis due to a viral infection. It results in inflammation of the meninges (the membranes covering the brain and spinal cord). Symptoms commonly include headache, fever, sensitivity to light and neck stiffness. Viruses are the most common cause of aseptic meningitis. Most cases of viral meningitis are caused by enteroviruses (common stomach viruses). However, other viruses can also cause viral meningitis, such as West Nile virus, mumps, measles, herpes simplex types I and II, varicella and lymphocytic choriomeningitis (LCM) virus. Based on clinical symptoms, viral meningitis cannot be reliably differentiated from bacterial meningitis, although viral meningitis typically follows a more benign clinical course. Viral meningitis has no evidence of bacteria present in cerebral spinal fluid (CSF). Therefore, lumbar puncture with CSF analysis is often needed to identify the disease. In most cases, there is no spe ...
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Major Histocompatibility Complex
The major histocompatibility complex (MHC) is a large locus on vertebrate DNA containing a set of closely linked polymorphic genes that code for cell surface proteins essential for the adaptive immune system. These cell surface proteins are called MHC molecules. This locus got its name because it was discovered via the study of transplanted tissue compatibility. Later studies revealed that tissue rejection due to incompatibility is only a facet of the full function of MHC molecules: binding an antigen derived from self-proteins, or from pathogens, and bringing the antigen presentation to the cell surface for recognition by the appropriate T-cells. MHC molecules mediate the interactions of leukocytes, also called white blood cells (WBCs), with other leukocytes or with body cells. The MHC determines donor compatibility for organ transplant, as well as one's susceptibility to autoimmune diseases. In a cell, protein molecules of the host's own phenotype or of other biologic entities ...
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T Cell
A T cell is a type of lymphocyte. T cells are one of the important white blood cells of the immune system and play a central role in the adaptive immune response. T cells can be distinguished from other lymphocytes by the presence of a T-cell receptor (TCR) on their cell surface. T cells are born from hematopoietic stem cells, found in the bone marrow. Developing T cells then migrate to the thymus gland to develop (or mature). T cells derive their name from the thymus. After migration to the thymus, the precursor cells mature into several distinct types of T cells. T cell differentiation also continues after they have left the thymus. Groups of specific, differentiated T cell subtypes have a variety of important functions in controlling and shaping the immune response. One of these functions is immune-mediated cell death, and it is carried out by two major subtypes: CD8+ "killer" and CD4+ "helper" T cells. (These are named for the presence of the cell surface proteins CD8 or ...
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Immune System
The immune system is a network of biological processes that protects an organism from diseases. It detects and responds to a wide variety of pathogens, from viruses to parasitic worms, as well as cancer cells and objects such as wood splinters, distinguishing them from the organism's own healthy tissue. Many species have two major subsystems of the immune system. The innate immune system provides a preconfigured response to broad groups of situations and stimuli. The adaptive immune system provides a tailored response to each stimulus by learning to recognize molecules it has previously encountered. Both use molecules and cells to perform their functions. Nearly all organisms have some kind of immune system. Bacteria have a rudimentary immune system in the form of enzymes that protect against virus infections. Other basic immune mechanisms evolved in ancient plants and animals and remain in their modern descendants. These mechanisms include phagocytosis, antimicrobial pe ...
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Canberra
Canberra ( ) is the capital city of Australia. Founded following the federation of the colonies of Australia as the seat of government for the new nation, it is Australia's largest inland city and the eighth-largest city overall. The city is located at the northern end of the Australian Capital Territory at the northern tip of the Australian Alps, the country's highest mountain range. As of June 2021, Canberra's estimated population was 453,558. The area chosen for the capital had been inhabited by Indigenous Australians for up to 21,000 years, with the principal group being the Ngunnawal people. European settlement commenced in the first half of the 19th century, as evidenced by surviving landmarks such as St John's Anglican Church and Blundells Cottage. On 1 January 1901, federation of the colonies of Australia was achieved. Following a long dispute over whether Sydney or Melbourne should be the national capital, a compromise was reached: the new capital would be buil ...
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Indooroopilly State High School
Indooroopilly State High School (ISHS), colloquially known as "Indro", is a state high school situated in the south-western suburb of Indooroopilly in Brisbane, Queensland, Australia. The school was founded in 1954, and offers the International Baccalaureate Diploma Programme, along with a large curriculum catering to junior and senior students at the school. Unlike most schools in Queensland and Australia, students at ISHS do not have to wear a school uniform. However, the school does have a sports uniform which students are required to wear during all interschool sports events. Some of the Indooroopilly State High School Buildings are listed on the Queensland Heritage Register. Facilities The school is made up of 23 different blocks. They are named in letter form in the order in which they were built. The letters range from A-X. Some of the facilities at the school include: * Confucius Institute Classroom * Dance and Art studios with a pottery kiln and film developing roo ...
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Oxley, Queensland
Oxley is a south-western suburb in the City of Brisbane, Queensland, Australia. In the , Oxley had a population of 8,336 people. Oxley is located approximately from the Brisbane CBD, but it is from the Brisbane GPO by road. The suburb contains a mix of residential and industrial land. Geography Oxley is bounded to the north by the Brisbane River and Oxley Creek flows along the eastern edge. In the east the environment is shaped by flood plains which experience major flooding and flash-flooding. Western parts of the suburb are characterised by rolling hills with clay-laden soils. The suburb is traversed by the Ipswich Motorway connecting Oxley to Rocklea to the east and Darra to the west. Oxley Road connects Oxley to Corinda to the north and continues south across the Ipswich Motorway with the name Blunder Road to Durack, Seventeen Mile Rocks Road connects Oxley to the west to Seventeen Mile Rocks and Darra. Oxley is separated from Fig Tree Pocket by the Brisbane River. ...
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Sherwood, Queensland
Sherwood is a suburb in the City of Brisbane, Queensland, Australia. In the , Sherwood had a population of 5,313 people. Geography Sherwood is south west of the Brisbane CBD and bounded by the median of the Brisbane River towards the west. Oxley Road is the main thoroughfare through the suburb, entering from the north ( Graceville) and exiting to the south (Corinda). The Ipswich railway line runs parallel to and west of Oxley Avenue, with the suburb served by Sherwood railway station (). The suburb is mostly low and medium-density housing with a retail strip centred along Sherwood Road. History West Oxley State School opened on 25 March 1867. It was renamed Sherwood State School in 1878. The first head teacher was Major William Jenyns Boyd. He was born in Paris in 1842 and migrated to Australia in 1862. In 1868, Oliver Radcliffe was the first name on the roll as a pupil teacher. He became a teacher, a headmaster and then a school inspector. By his retirement in 1932, h ...
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Queensland Government
The Queensland Government is the democratic administrative authority of the Australian state of Queensland. The Government of Queensland, a parliamentary constitutional monarchy was formed in 1859 as prescribed in its Constitution, as amended from time to time. Since the Federation of Australia in 1901, Queensland has been a State of Australia, with the Constitution of Australia regulating the relationships between all state and territory governments and the Australian Government. Under the Australian Constitution, all states and territories (including Queensland) ceded powers relating to certain matters to the federal government. The government is influenced by the Westminster system and Australia's federal system of government. The Governor of Queensland, as the representative of Charles III, King of Australia, holds nominal executive power, although in practice only performs ceremonial duties. In practice executive power lies with the Premier and Cabinet. The Cabinet of ...
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