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Pentanonide
In organic chemistry, pentanonide is a functional group which is composed of a cyclic ketal of a diol with 3-pentanone. It is seen in amcinafal (triamcinolone pentanonide). See also * Acetonide In organic chemistry, an acetonide is the functional group composed of the cyclic ketal of a diol with acetone. The more systematic name for this structure is an isopropylidene ketal. Acetonide is a common protecting group for 1,2- and 1,3- diol ... * Acetophenide * Acroleinide * Aminobenzal * Cyclopentanonide References {{organic-chemistry-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Amcinafal
Amcinafal (developmental code name SQ-15102), also known as triamcinolone pentanonide, is a synthetic glucocorticoid Glucocorticoids (or, less commonly, glucocorticosteroids) are a class of corticosteroids, which are a class of steroid hormones. Glucocorticoids are corticosteroids that bind to the glucocorticoid receptor that is present in almost every verteb ... corticosteroid which was never marketed. References Corticosteroid cyclic ketals Diketones Diols Fluoroarenes Glucocorticoids Pentanonides Pregnanes {{steroid-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Acetonide
In organic chemistry, an acetonide is the functional group composed of the cyclic ketal of a diol with acetone. The more systematic name for this structure is an isopropylidene ketal. Acetonide is a common protecting group for 1,2- and 1,3- diols. The protecting group can be removed by hydrolysis of the ketal using dilute aqueous acid. Example The acetonides of small di- and triols, as well as many sugars and sugar alcohols, are common. The hexaol mannitol reacts with 2,2-dimethoxypropane to give the bis-acetonide, which oxidizes to give the acetonide of glyceraldehyde: :(CHOHCHOHCH2OH)2 + 2 (MeO)2CMe2 → (CHOHCHCH2O2CMe2)2 + 4 MeOH :(CHOHCHOCH2OCMe2)2 + → 2 OCHCHCH2O2CMe2 + H2O An example of its use as a protecting group in a complex organic synthesis is the Nicolaou Taxol total synthesis. It is a common protecting group for sugars and sugar alcohols, a simple example being solketal. The acetonides of corticosteroid are used in dermatology, because their increased l ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Acetophenide
In organic chemistry, acetophenide is a functional group which is composed of the cyclic ketal of a diol with acetophenone. In pharmaceutical chemistry, it is present in algestone acetophenide (dihydroxyprogesterone acetophenide) and amcinafide (triamcinolone acetophenide). See also * Acetonide * Acroleinide * Aminobenzal * Cyclopentanonide * Pentanonide In organic chemistry, pentanonide is a functional group which is composed of a cyclic ketal of a diol with 3-pentanone. It is seen in amcinafal (triamcinolone pentanonide). See also * Acetonide In organic chemistry, an acetonide is the functio ... References {{organic-chemistry-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Acroleinide
In organic chemistry, acroleinide is a functional group which is composed of a cyclic ketal of a diol with acrolein. In pharmaceutical chemistry, it is present in acrocinonide (triamcinolone acroleinide). See also * Acetonide * Acetophenide * Aminobenzal * Cyclopentanonide * Pentanonide In organic chemistry, pentanonide is a functional group which is composed of a cyclic ketal of a diol with 3-pentanone. It is seen in amcinafal (triamcinolone pentanonide). See also * Acetonide In organic chemistry, an acetonide is the functio ... References {{organic-chemistry-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Aminobenzal
In organic chemistry, aminobenzal is a functional group which is composed of a cyclic ketal of a diol with 4-dimethylaminobenzylidene. It is seen in triamcinolone aminobenzal benzamidoisobutyrate. See also * Acetonide * Acetophenide * Acroleinide * Cyclopentanonide * Pentanonide In organic chemistry, pentanonide is a functional group which is composed of a cyclic ketal of a diol with 3-pentanone. It is seen in amcinafal (triamcinolone pentanonide). See also * Acetonide In organic chemistry, an acetonide is the functio ... References {{organic-chemistry-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cyclopentanonide
In organic chemistry, cyclopentanonide is a functional group which is composed of a cyclic ketal of a diol with cyclopentanone. It is seen in amcinonide (triamcinolone acetate cyclopentanonide). See also * Acetonide * Acetophenide * Acroleinide * Aminobenzal * Pentanonide In organic chemistry, pentanonide is a functional group which is composed of a cyclic ketal of a diol with 3-pentanone. It is seen in amcinafal (triamcinolone pentanonide). See also * Acetonide In organic chemistry, an acetonide is the functio ... References Cyclopentanonides {{organic-chemistry-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Organic Chemistry
Organic chemistry is a subdiscipline within chemistry involving the scientific study of the structure, properties, and reactions of organic compounds and organic materials, i.e., matter in its various forms that contain carbon atoms.Clayden, J.; Greeves, N. and Warren, S. (2012) ''Organic Chemistry''. Oxford University Press. pp. 1–15. . Study of structure determines their structural formula. Study of properties includes physical and chemical properties, and evaluation of chemical reactivity to understand their behavior. The study of organic reactions includes the chemical synthesis of natural products, drugs, and polymers, and study of individual organic molecules in the laboratory and via theoretical ( in silico) study. The range of chemicals studied in organic chemistry includes hydrocarbons (compounds containing only carbon and hydrogen) as well as compounds based on carbon, but also containing other elements, especially oxygen, nitrogen, sulfur, phosphorus (i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Functional Group
In organic chemistry, a functional group is a substituent or moiety in a molecule that causes the molecule's characteristic chemical reactions. The same functional group will undergo the same or similar chemical reactions regardless of the rest of the molecule's composition. This enables systematic prediction of chemical reactions and behavior of chemical compounds and the design of chemical synthesis. The reactivity of a functional group can be modified by other functional groups nearby. Functional group interconversion can be used in retrosynthetic analysis to plan organic synthesis. A functional group is a group of atoms in a molecule with distinctive chemical properties, regardless of the other atoms in the molecule. The atoms in a functional group are linked to each other and to the rest of the molecule by covalent bonds. For repeating units of polymers, functional groups attach to their nonpolar core of carbon atoms and thus add chemical character to carbon chains. F ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cyclic Compound
A cyclic compound (or ring compound) is a term for a compound in the field of chemistry in which one or more series of atoms in the compound is connected to form a ring. Rings may vary in size from three to many atoms, and include examples where all the atoms are carbon (i.e., are carbocycles), none of the atoms are carbon (inorganic cyclic compounds), or where both carbon and non-carbon atoms are present ( heterocyclic compounds). Depending on the ring size, the bond order of the individual links between ring atoms, and their arrangements within the rings, carbocyclic and heterocyclic compounds may be aromatic or non-aromatic; in the latter case, they may vary from being fully saturated to having varying numbers of multiple bonds between the ring atoms. Because of the tremendous diversity allowed, in combination, by the valences of common atoms and their ability to form rings, the number of possible cyclic structures, even of small size (e.g., < 17 total atoms) numbers in the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ketal
In organic chemistry, an acetal is a functional group with the connectivity . Here, the R groups can be organic fragments (a carbon atom, with arbitrary other atoms attached to that) or hydrogen, while the R' groups must be organic fragments not hydrogen. The two R' groups can be equivalent to each other (a "symmetric acetal") or not (a "mixed acetal"). Acetals are formed from and convertible to aldehydes or ketones and have the same oxidation state at the central carbon, but have substantially different chemical stability and reactivity as compared to the analogous carbonyl compounds. The central carbon atom has four bonds to it, and is therefore saturated and has tetrahedral geometry. The term ketal is sometimes used to identify structures associated with ketones (both R groups organic fragments rather than hydrogen) rather than aldehydes and, historically, the term acetal was used specifically for the aldehyde-related cases (having at least one hydrogen in place of an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Diol
A diol is a chemical compound containing two hydroxyl groups ( groups). An aliphatic diol is also called a glycol. This pairing of functional groups is pervasive, and many subcategories have been identified. The most common industrial diol is ethylene glycol. Examples of diols in which the hydroxyl functional groups are more widely separated include 1,4-butanediol and propylene-1,3-diol, or beta propylene glycol, . Synthesis of classes of diols Geminal diols A geminal diol has two hydroxyl groups bonded to the same atom. These species arise by hydration of the carbonyl compounds. The hydration is usually unfavorable, but a notable exception is formaldehyde which, in water, exists in equilibrium with methanediol H2C(OH)2. Another example is (F3C)2C(OH)2, the hydrated form of hexafluoroacetone. Many gem-diols undergo further condensation to give dimeric and oligomeric derivatives. This reaction applies to glyoxal and related aldehydes. Vicinal diols In a vicinal diol, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
