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Penicillium Citrinum
''Penicillium citrinum'' is an anamorph, mesophilic fungus species of the genus of ''Penicillium'' which produces tanzawaic acid A-D, ACC, Mevastatin, Quinocitrinine A, Quinocitrinine B, and nephrotoxic citrinin. ''Penicillium citrinum'' is often found on moldy citrus fruits and occasionally it occurs in tropical spices and cereals. This Penicillium species also causes mortality for the mosquito Culex quinquefasciatus. Because of its mesophilic character, ''Penicillium citrinum'' occurs worldwide. The first statin (''Mevastatin'') was 1970 isolated from this species. Further reading * * * * * * * * * Fatal Penicillium citrinum Pneumonia with Pericarditis in a Patient with Acute Leukemia* * * See also *List of Penicillium species This is a list of ''Penicillium'' species. The genus has over 300 species. Species A * '' Penicillium abidjanum'' * '' Penicillium adametzii'' * '' Penicillium adametzioides'' * '' Penicillium aeris'' * '' Penicillium aeth ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Charles Thom
Charles Thom (November 11, 1872 – May 24, 1956) was an American microbiologist and mycologist. Born and raised in Illinois, he received his PhD from the University of Missouri, the first such degree awarded by that institution. He was best known for his work on the microbiology of dairy products and soil fungi, and in particular his research into the genera ''Aspergillus'' and ''Penicillium''. His work influenced the establishment of standards for food handling and processing in the USA. He pioneered the use of culture media to grow microorganisms, and, with food chemist James N. Currie, developed a process to mass-produce citric acid using ''Aspergillus''. Thom played an important role in the development of penicillin in World War II. Early life Thom was born in Minonk, Illinois in 1872, the fifth of six boys. His parents were Angus Sutherland Thom and Louisa (Herick) Thom, Scottish/Irish farmers who had settled in Illinois shortly before the American Civil War. Charles Th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Citrinin
Citrinin is a mycotoxin which is often found in food. It is a secondary metabolite produced by fungi that contaminates long-stored food and it causes different toxic effects, like nephrotoxic, hepatotoxic and cytotoxic effects. Citrinin is mainly found in stored grains, but sometimes also in fruits and other plant products. History Citrinin was one of the many mycotoxins discovered by H. Raistrick and A.C. Hetherington in the 1930s. In 1941 H. Raistrick and G. Smith identified citrinin to have a broad antibacterial activity. After this discovery the interest in citrinin rose. However, in 1946 A.M. Ambrose and F. DeEds demonstrated that citrinin was toxic to mammals. As a result, the interest in citrinin decreased, but there still was a lot of research. In 1948 the chemical structure was found by W.B. Whalley and coworkers. Citrinin is a natural compound and it was first isolated from ''Penicillium citrinum'', but is also produced by other ''Penicillium'' species, such as the ''Mo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fungi Described In 1910
A fungus ( : fungi or funguses) is any member of the group of eukaryotic organisms that includes microorganisms such as yeasts and molds, as well as the more familiar mushrooms. These organisms are classified as a kingdom, separately from the other eukaryotic kingdoms, which by one traditional classification include Plantae, Animalia, Protozoa, and Chromista. A characteristic that places fungi in a different kingdom from plants, bacteria, and some protists is chitin in their cell walls. Fungi, like animals, are heterotrophs; they acquire their food by absorbing dissolved molecules, typically by secreting digestive enzymes into their environment. Fungi do not photosynthesize. Growth is their means of mobility, except for spores (a few of which are flagellated), which may travel through the air or water. Fungi are the principal decomposers in ecological systems. These and other differences place fungi in a single group of related organisms, named the ''Eumycota'' (''true fungi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
List Of Penicillium Species
This is a list of ''Penicillium'' species. The genus has over 300 species. Species A * '' Penicillium abidjanum'' * '' Penicillium adametzii'' * '' Penicillium adametzioides'' * '' Penicillium aeris'' * '' Penicillium aethiopicum'' * '' Penicillium albicans'' * '' Penicillium albidum '' * ''Penicillium albocoremium'' * '' Penicillium alexiae'' * '' Penicillium alfredii'' * '' Penicillium alicantinum'' * '' Penicillium allahabadense'' * '' Penicillium allii'' * '' Penicillium allii-sativi'' * '' Penicillium alogum'' * '' Penicillium alutaceum'' * ''Penicillium anatolicum'' * '' Penicillium amagasakiense'' * '' Penicillium amaliae'' * '' Penicillium amphipolaria'' * ''Penicillium anatolicum'' * ''Penicillium angulare'' * ''Penicillium angustiporcatum'' * ''Penicillium antarcticum'' * ''Penicillium annulatum'' * ''Penicillium aotearoae'' * ''Penicillium araracuarense'' * ''Penicillium ardesiacum'' * ''Penicillium arenicola'' * ''Penicillium aragonense'' * ''Penicillium arian ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Statin
Statins, also known as HMG-CoA reductase inhibitors, are a class of lipid-lowering medications that reduce illness and mortality in those who are at high risk of cardiovascular disease. They are the most common cholesterol-lowering drugs. Low-density lipoprotein (LDL) carriers of cholesterol play a key role in the development of atherosclerosis and coronary heart disease via the mechanisms described by the lipid hypothesis. Statins are effective in lowering LDL cholesterol and so are widely used for primary prevention in people at high risk of cardiovascular disease, as well as in secondary prevention for those who have developed cardiovascular disease. Side effects of statins include muscle pain, increased risk of diabetes mellitus, and abnormal blood levels of liver enzymes. Additionally, they have rare but severe adverse effects, particularly muscle damage. They inhibit the enzyme HMG-CoA reductase which plays a central role in the production of cholesterol. High cholester ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Culex Quinquefasciatus
''Culex'' is a genus of mosquitoes, several species of which serve as vectors of one or more important diseases of birds, humans, and other animals. The diseases they vector include arbovirus infections such as West Nile virus, Japanese encephalitis, or St. Louis encephalitis, but also filariasis and avian malaria. They occur worldwide except for the extreme northern parts of the temperate zone, and are the most common form of mosquito encountered in some major U.S. cities, such as Los Angeles. Etymology In naming this genus, Carl Linnaeus appropriated the nonspecific Latin term for a midge or gnat: '. Description Depending on the species, the adult ''Culex'' mosquito may measure from . The adult morphology is typical of flies in the suborder Nematocera with the head, thorax, and abdomen clearly defined and the two forewings held horizontally over the abdomen when at rest. As in all Diptera capable of flight, the second pair of wings is reduced and modified into tiny, incon ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cereals
A cereal is any grass cultivated for the edible components of its grain (botanically, a type of fruit called a caryopsis), composed of the endosperm, germ, and bran. Cereal grain crops are grown in greater quantities and provide more food energy worldwide than any other type of crop and are therefore staple crops. They include wheat, rye, oats, and barley. Edible grains from other plant families, such as buckwheat, quinoa and chia, are referred to as pseudocereals. In their unprocessed whole grain form, cereals are a rich source of vitamins, minerals, carbohydrates, fats, oils, and protein. When processed by the removal of the bran and germ the remaining endosperm is mostly carbohydrate. In some developing countries, grain in the form of rice, wheat, millet, or maize constitutes a majority of daily sustenance. In developed countries, cereal consumption is moderate and varied but still substantial, primarily in the form of refined and processed grains. Because of this dieta ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Spices
A spice is a seed, fruit, root, Bark (botany), bark, or other plant substance primarily used for flavoring or coloring food. Spices are distinguished from herbs, which are the leaves, flowers, or stems of plants used for flavoring or as a garnish (food), garnish. Spices are sometimes used in medicine, Sacred rite, religious rituals, cosmetics or perfume production. For example, vanilla is commonly used as an ingredient in Aroma compound, fragrance manufacturing. A spice may be available in several forms: fresh, whole dried, or pre-ground dried. Generally, spices are dried. Spices may be ground into a powder for convenience. A whole dried spice has the longest shelf life, so it can be purchased and stored in larger amounts, making it cheaper on a per-serving basis. A fresh spice, such as ginger, is usually more flavorful than its dried form, but fresh spices are more expensive and have a much shorter shelf life. Some spices are not always available either fresh or whole, for exam ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Citrus Fruits
''Citrus'' is a genus Genus ( plural genera ) is a taxonomic rank used in the biological classification of extant taxon, living and fossil organisms as well as Virus classification#ICTV classification, viruses. In the hierarchy of biological classification, genus com ... of flowering plant, flowering trees and shrubs in the rue family, Rutaceae. Plants in the genus produce citrus fruits, including important crops such as Orange (fruit), oranges, Lemon, lemons, grapefruits, pomelos, and lime (fruit), limes. The genus ''Citrus'' is native to South Asia, East Asia, Southeast Asia, Melanesia, and Australia (continent), Australia. Various citrus species have been used and domesticated by indigenous cultures in these areas since ancient times. From there its cultivation spread into Micronesia and Polynesia by the Austronesian expansion (c. 3000–1500 BCE); and to the Middle East and the Mediterranean (c. 1200 BCE) via the incense trade route, and onwards to Europe and the Americas ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nephrotoxic
Nephrotoxicity is toxicity in the kidneys. It is a poisonous effect of some substances, both toxic chemicals and medications, on kidney function. There are various forms, and some drugs may affect kidney function in more than one way. Nephrotoxins are substances displaying nephrotoxicity. Nephrotoxicity should not be confused with some medications predominantly excreted by the kidneys needing their dose adjusted for the decreased kidney function (e.g., heparin, lithium). Types of toxicity Cardiovascular * General: diuretics, β-blockers, vasodilator agents * Local: ACE inhibitors, ciclosporin, tacrolimus. Direct tubular effect * Proximal convoluted tubule: Aminoglycoside antibiotics (e.g., gentamicin), amphotericin B, cisplatin, radiocontrast media, immunoglobulins, mannitol * Distal tubule: NSAIDs (e.g. aspirin, ibuprofen, diclofenac), ACE inhibitors, ciclosporin, lithium salts, cyclophosphamide, amphotericin B * Tubular obstruction: sulphonamides, methotrexate, aciclovir, diet ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Anamorph
In mycology, the terms teleomorph, anamorph, and holomorph apply to portions of the life cycles of fungi in the phyla Ascomycota and Basidiomycota: *Teleomorph: the sexual reproductive stage (morph), typically a fruiting body. *Anamorph: an asexual reproductive stage (morph), often mold-like. When a single fungus produces multiple morphologically distinct anamorphs, these are called synanamorphs. *Holomorph: the whole fungus, including anamorphs and teleomorph. Dual naming of fungi Fungi are classified primarily based on the structures associated with sexual reproduction, which tend to be evolutionarily conserved. However, many fungi reproduce only asexually, and cannot easily be classified based on sexual characteristics; some produce both asexual and sexual states. These problematic species are often members of the Ascomycota, but a few of them belong to the Basidiomycota. Even among fungi that reproduce both sexually and asexually, often only one method of reproduction can be ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Quinocitrinine
Quinocitrinines A and B Quinocitrinines are quinoline alkaloids Quinoline alkaloids are naturally occurring chemical compounds from the group of alkaloids, which are chemically derived from quinoline. Some quinoline alkaloids show antiseptic, convulsive or antineoplastic effects. Examples Alkaloids with a ... isolated from a permafrost ''Penicillium''. Further reading * * *{{cite journal , last1=Antipova , first1=T. V. , last2=Zhelifonova , first2=V. P. , last3=Baskunov , first3=B. P. , last4=Ozerskaya , first4=S. M. , last5=Ivanushkina , first5=N. E. , last6=Kozlovsky , first6=A. G. , year=2011 , title=New producers of biologically active compounds—fungal strains of the genus Penicillium isolated from permafrost , journal=Applied Biochemistry and Microbiology , volume=47 , issue=3 , pages=288–92 , doi=10.1134/S0003683811030033 Penicillium Quinoline alkaloids Nitrogen heterocycles ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
