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''Penicillium citrinum'' is an anamorph, mesophilic
fungus A fungus ( : fungi or funguses) is any member of the group of eukaryotic organisms that includes microorganisms such as yeasts and molds, as well as the more familiar mushrooms. These organisms are classified as a kingdom, separately from t ...
species of the genus of ''
Penicillium ''Penicillium'' () is a genus of ascomycetous fungi that is part of the mycobiome of many species and is of major importance in the natural environment, in food spoilage, and in food and drug production. Some members of the genus produce pe ...
'' which produces tanzawaic acid A-D, ACC, Mevastatin, Quinocitrinine A, Quinocitrinine B, and
nephrotoxic Nephrotoxicity is toxicity in the kidneys. It is a poisonous effect of some substances, both toxic chemicals and medications, on kidney function. There are various forms, and some drugs may affect kidney function in more than one way. Nephrotoxins ...
citrinin. ''Penicillium citrinum'' is often found on moldy
citrus fruits ''Citrus'' is a genus of flowering trees and shrubs in the rue family, Rutaceae. Plants in the genus produce citrus fruits, including important crops such as oranges, lemons, grapefruits, pomelos, and limes. The genus ''Citrus'' is nativ ...
and occasionally it occurs in tropical spices and
cereals A cereal is any grass cultivated for the edible components of its grain (botanically, a type of fruit called a caryopsis), composed of the endosperm, germ, and bran. Cereal grain crops are grown in greater quantities and provide more food ...
. This Penicillium species also causes mortality for the mosquito
Culex quinquefasciatus ''Culex'' is a genus of mosquitoes, several species of which serve as vectors of one or more important diseases of birds, humans, and other animals. The diseases they vector include arbovirus infections such as West Nile virus, Japanese encep ...
. Because of its mesophilic character, ''Penicillium citrinum'' occurs worldwide. The first
statin Statins, also known as HMG-CoA reductase inhibitors, are a class of lipid-lowering medications that reduce illness and mortality in those who are at high risk of cardiovascular disease. They are the most common cholesterol-lowering drugs. Low ...
(''Mevastatin'') was 1970 isolated from this species.


Further reading

* * * * * * * * *
Fatal Penicillium citrinum Pneumonia with Pericarditis in a Patient with Acute Leukemia
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See also

*
List of Penicillium species This is a list of ''Penicillium'' species. The genus has over 300 species. Species A * '' Penicillium abidjanum'' * '' Penicillium adametzii'' * '' Penicillium adametzioides'' * '' Penicillium aeris'' * '' Penicillium aethiopicum'' * '' Penic ...


References

{{Taxonbar, from=Q10622902 citrinum Fungi described in 1910 Medicinal fungi Taxa named by Charles Thom