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Pedro Cuatrecasas
Pedro Cuatrecasas (born 27 September 1936) is an American biochemist and an Adjunct Professor of Pharmacology & Medicine at the University of California San Diego. Birth and education Pedro Cuatrecasas was born in 1936 in Madrid, Spain. He completed his A.B. from Washington University in St. Louis in 1958. He completed his M.D. from Washington University School of Medicine in 1962. Research Pedro Cuatrecasas is known for the invention and development of affinity chromatography, a process utilized within the Aethlon HemopurifierTM. He was involved in the discovery, development and marketing registration of more than forty medicines. Some of those medicines include: zidovudine (AZT, AIDS), acyclovir (Zovirax, anti-herpes), permethrin (Rid, head and body lice), bupropion (Wellbutrin, antidepressant), colfosceril palmitate (Exosurf, infant acute respiratory distress), remifentanil (Ultiva, analgesic/anesthetic), sumatriptan (Imigran, migraine), salmeterol (Serement, asthma), tacr ...
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Troglitazone
Troglitazone is an antidiabetic and anti-inflammatory drug, and a member of the drug class of the thiazolidinediones. It was prescribed for people with diabetes mellitus type 2. It was patented in 1983 and approved for medical use in 1997. It was subsequently withdrawn. Mechanism of action Troglitazone, like the other thiazolidinediones (pioglitazone and rosiglitazone), works by activating peroxisome proliferator-activated receptors (PPARs). Troglitazone is a ligand to both PPARα and – more strongly – PPARγ. Troglitazone also contains an α-Tocopherol moiety, potentially giving it vitamin E-like activity in addition to its PPAR activation. It has been shown to reduce inflammation. Troglitazone use was associated with a decrease of nuclear factor kappa-B (NF-κB) and a concomitant increase in its inhibitor (IκB). NFκB is an important cellular transcription regulator for the immune response. History Troglitazone was developed by Daiichi Sankyo (Japan). In the United ...
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Members Of The United States National Academy Of Sciences
Member may refer to: * Military jury, referred to as "Members" in military jargon * Element (mathematics), an object that belongs to a mathematical set * In object-oriented programming, a member of a class ** Field (computer science), entries in a database ** Member variable, a variable that is associated with a specific object * Limb (anatomy), an appendage of the human or animal body ** Euphemism for penis * Structural component of a truss, connected by nodes * User (computing), a person making use of a computing service, especially on the Internet * Member (geology), a component of a geological formation * Member of parliament * The Members, a British punk rock band * Meronymy, a semantic relationship in linguistics * Church membership, belonging to a local Christian congregation, a Christian denomination and the universal Church * Member, a participant in a club or learned society A learned society (; also learned academy, scholarly society, or academic association) is an ...
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Living People
Related categories * :Year of birth missing (living people) / :Year of birth unknown * :Date of birth missing (living people) / :Date of birth unknown * :Place of birth missing (living people) / :Place of birth unknown * :Year of death missing / :Year of death unknown * :Date of death missing / :Date of death unknown * :Place of death missing / :Place of death unknown * :Missing middle or first names See also * :Dead people * :Template:L, which generates this category or death years, and birth year and sort keys. : {{DEFAULTSORT:Living people 21st-century people People by status ...
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Wolf Prize In Medicine Laureates
The wolf (''Canis lupus''; : wolves), also known as the gray wolf or grey wolf, is a large canine native to Eurasia and North America. More than thirty subspecies of ''Canis lupus'' have been recognized, and gray wolves, as popularly understood, comprise wild subspecies. The wolf is the largest extant member of the family Canidae. It is also distinguished from other ''Canis'' species by its less pointed ears and muzzle, as well as a shorter torso and a longer tail. The wolf is nonetheless related closely enough to smaller ''Canis'' species, such as the coyote and the golden jackal, to produce fertile hybrids with them. The banded fur of a wolf is usually mottled white, brown, gray, and black, although subspecies in the arctic region may be nearly all white. Of all members of the genus ''Canis'', the wolf is most specialized for cooperative game hunting as demonstrated by its physical adaptations to tackling large prey, its more social nature, and its highly advanced ...
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University Of California, San Diego Alumni
A university () is an institution of higher (or tertiary) education and research which awards academic degrees in several academic disciplines. Universities typically offer both undergraduate and postgraduate programs. In the United States, the designation is reserved for colleges that have a graduate school. The word ''university'' is derived from the Latin ''universitas magistrorum et scholarium'', which roughly means "community of teachers and scholars". The first universities were created in Europe by Catholic Church monks. The University of Bologna (''Università di Bologna''), founded in 1088, is the first university in the sense of: *Being a high degree-awarding institute. *Having independence from the ecclesiastic schools, although conducted by both clergy and non-clergy. *Using the word ''universitas'' (which was coined at its foundation). *Issuing secular and non-secular degrees: grammar, rhetoric, logic, theology, canon law, notarial law.Hunt Janin: "The university ...
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Washington University School Of Medicine Alumni
Washington commonly refers to: * Washington (state), United States * Washington, D.C., the capital of the United States ** A metonym for the federal government of the United States ** Washington metropolitan area, the metropolitan area centered on Washington, D.C. * George Washington (1732–1799), the first president of the United States Washington may also refer to: Places England * Washington, Tyne and Wear, a town in the City of Sunderland metropolitan borough ** Washington Old Hall, ancestral home of the family of George Washington * Washington, West Sussex, a village and civil parish Greenland * Cape Washington, Greenland * Washington Land Philippines *New Washington, Aklan, a municipality *Washington, a barangay in Catarman, Northern Samar *Washington, a barangay in Escalante, Negros Occidental *Washington, a barangay in San Jacinto, Masbate *Washington, a barangay in Surigao City United States * Washington, Wisconsin (other) * Fort Washington (disambiguation ...
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Spanish Biochemists
Spanish might refer to: * Items from or related to Spain: **Spaniards are a nation and ethnic group indigenous to Spain **Spanish language, spoken in Spain and many Latin American countries **Spanish cuisine Other places * Spanish, Ontario, Canada * Spanish River (other), the name of several rivers * Spanish Town, Jamaica Other uses * John J. Spanish (1922–2019), American politician * "Spanish" (song), a single by Craig David, 2003 See also * * * Español (other) * Spain (other) * España (other) * Espanola (other) * Hispania, the Roman and Greek name for the Iberian Peninsula * Hispanic, the people, nations, and cultures that have a historical link to Spain * Hispanic (other) * Hispanism * Spain (other) * National and regional identity in Spain * Culture of Spain * Spanish Fort (other) Spanish Fort or Old Spanish Fort may refer to: United States * Spanish Fort, Alabama, a city * Spanish Fort (Colorad ...
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American Biochemists
American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, people who self-identify their ancestry as "American" ** American English, the set of varieties of the English language native to the United States ** Native Americans in the United States, indigenous peoples of the United States * American, something of, from, or related to the Americas, also known as "America" ** Indigenous peoples of the Americas * American (word), for analysis and history of the meanings in various contexts Organizations * American Airlines, U.S.-based airline headquartered in Fort Worth, Texas * American Athletic Conference, an American college athletic conference * American Recordings (record label), a record label previously known as Def American * American University, in Washington, D.C. Sports teams Soccer * B ...
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Spanish Emigrants To The United States
Spanish might refer to: * Items from or related to Spain: **Spaniards are a nation and ethnic group indigenous to Spain **Spanish language, spoken in Spain and many Latin American countries **Spanish cuisine Other places * Spanish, Ontario, Canada * Spanish River (other), the name of several rivers * Spanish Town, Jamaica Other uses * John J. Spanish (1922–2019), American politician * "Spanish" (song), a single by Craig David, 2003 See also * * * Español (other) * Spain (other) * España (other) * Espanola (other) * Hispania, the Roman and Greek name for the Iberian Peninsula * Hispanic, the people, nations, and cultures that have a historical link to Spain * Hispanic (other) * Hispanism * Spain (other) * National and regional identity in Spain * Culture of Spain * Spanish Fort (other) Spanish Fort or Old Spanish Fort may refer to: United States * Spanish Fort, Alabama, a city * Spanish Fort (Color ...
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1936 Births
Events January–February * January 20 – George V of the United Kingdom and the British Dominions and Emperor of India, dies at his Sandringham Estate. The Prince of Wales succeeds to the throne of the United Kingdom as King Edward VIII. * January 28 – Britain's King George V state funeral takes place in London and Windsor. He is buried at St George's Chapel, Windsor Castle * February 4 – Radium E (bismuth-210) becomes the first radioactive element to be made synthetically. * February 6 – The 1936 Winter Olympics, IV Olympic Winter Games open in Garmisch-Partenkirchen, Germany. * February 10–February 19, 19 – Second Italo-Ethiopian War: Battle of Amba Aradam – Italian forces gain a decisive tactical victory, effectively neutralizing the army of the Ethiopian Empire. * February 16 – 1936 Spanish general election: The left-wing Popular Front (Spain), Popular Front coalition takes a majority. * February 26 – February 26 Inci ...
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Affinity Chromatography
Affinity chromatography is a method of separating a biomolecule from a mixture, based on a highly specific macromolecular binding interaction between the biomolecule and another substance. The specific type of binding interaction depends on the biomolecule of interest; antigen and antibody, enzyme and substrate, receptor and ligand, or protein and nucleic acid binding interactions are frequently exploited for isolation of various biomolecules. Affinity chromatography is useful for its high selectivity and resolution of separation, compared to other chromatographic methods. Principle Affinity chromatography has the advantage of specific binding interactions between the analyte of interest (normally dissolved in the mobile phase), and a binding partner or ligand (immobilized on the stationary phase). In a typical affinity chromatography experiment, the ligand is attached to a solid, insoluble matrix—usually a polymer such as agarose or polyacrylamide—chemically modified ...
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