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Paul Ehrlich Institute
The Paul Ehrlich Institute (German: ''Paul-Ehrlich-Institut – Bundesinstitut für Impfstoffe und biomedizinische Arzneimittel'', PEI) is a German federal agency, medical regulatory body and research institution for vaccines and biomedicines. It was founded in 1896 and is subordinate to the Federal Ministry of Health. The institute is a WHO Collaborating Centre for quality assurance of blood products and ''in vitro'' diagnostic devices. It is located in Langen, Hesse, near Frankfurt, and was located in Frankfurt for most of the 20th century. It is named for its founding director, the immunologist and Nobel Prize laureate Paul Ehrlich. History The Paul Ehrlich Institute was founded on 1 June 1896 in Steglitz, Berlin as the Institute for Serum Research and Serum Testing (Institut für Serumforschung und Serumprüfung), with immunologist Paul Ehrlich, one of Germany's most prominent medical researchers at the time, as its first director. The institute was founded specifically to p ...
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Langen, Hesse
Langen is a town of roughly 39,000 in the Offenbach district in the ''Regierungsbezirk'' of Darmstadt in Hesse, Germany. The town is between Darmstadt and Frankfurt am Main and part of the Frankfurt Rhein-Main urban area. Langen is headquarters to Deutsche Flugsicherung (German air traffic control), and is also home to the Paul-Ehrlich-Institut, a Federal institute for the evaluation and supervision of sera and vaccines in Germany. Geography Neighbouring communities Langen borders in the north and northeast on the town of Dreieich, in the south on the community of Egelsbach and in the west on the town of Mörfelden-Walldorf ( Groß-Gerau district). Constituent communities Langen is only subdivided internally. Its '' Stadtteile'' are: * Altstadt ("Old Town") in the east. This lies within the former eastern town wall, parts of which may still be seen. There is an ''Altstadtordnung'' ("Old Town Order") in force for the Old Town, meant to preserve the many timber-frame hou ...
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Antibodies
An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein used by the immune system to identify and neutralize foreign objects such as pathogenic bacteria and viruses. The antibody recognizes a unique molecule of the pathogen, called an antigen. Each tip of the "Y" of an antibody contains a paratope (analogous to a lock) that is specific for one particular epitope (analogous to a key) on an antigen, allowing these two structures to bind together with precision. Using this binding mechanism, an antibody can ''tag'' a microbe or an infected cell for attack by other parts of the immune system, or can neutralize it directly (for example, by blocking a part of a virus that is essential for its invasion). To allow the immune system to recognize millions of different antigens, the antigen-binding sites at both tips of the antibody come in an equally wide variety. In contrast, the remainder of the antibody is relatively constant. It only occurs in a few vari ...
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Organisations Based In Berlin
An organization or organisation (Commonwealth English; see spelling differences), is an entity—such as a company, an institution, or an association—comprising one or more people and having a particular purpose. The word is derived from the Greek word ''organon'', which means tool or instrument, musical instrument, and organ. Types There are a variety of legal types of organizations, including corporations, governments, non-governmental organizations, political organizations, international organizations, armed forces, charities, not-for-profit corporations, partnerships, cooperatives, and educational institutions, etc. A hybrid organization is a body that operates in both the public sector and the private sector simultaneously, fulfilling public duties and developing commercial market activities. A voluntary association is an organization consisting of volunteers. Such organizations may be able to operate without legal formalities, depending on jurisdiction, includin ...
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World Health Organization Collaborating Centres
World Health Organization collaborating centres are institutions that work with the World Health Organization (WHO) in disciplines such as occupational health, food safety, and communicable disease prevention. There are over 700 such centres across 80 countries. Collaborating centres may be research institutes, parts of universities, or academies. The participating institutions partner with WHO to perform research, provide training, or offer other services in furthering the WHO health agenda. These partners are designated by the WHO director-general as a part of a collaborative network. By using networks of established organizations, WHO is able to strengthen the scientific validity of its work and lower the costs of research. Centres worldwide The World Health Organization has established networks related to a variety of health topics. For example, WHO has put in place centres focused on organ transplants, hearing loss prevention, hepatitis, leprosy, medical ethics, and maternal he ...
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German Federal Agencies
German(s) may refer to: * Germany (of or related to) ** Germania (historical use) * Germans, citizens of Germany, people of German ancestry, or native speakers of the German language ** For citizens of Germany, see also German nationality law **Germanic peoples (Roman times) * German language **any of the Germanic languages * German cuisine, traditional foods of Germany People * German (given name) * German (surname) * Germán, a Spanish name Places * German (parish), Isle of Man * German, Albania, or Gërmej * German, Bulgaria * German, Iran * German, North Macedonia * German, New York, U.S. * Agios Germanos, Greece Other uses * German (mythology), a South Slavic mythological being * Germans (band), a Canadian rock band * "German" (song), a 2019 song by No Money Enterprise * ''The German'', a 2008 short film * "The Germans", an episode of ''Fawlty Towers'' * ''The German'', a nickname for Congolese rebel André Kisase Ngandu See also * Germanic (other) * G ...
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Paul Ehrlich Institute
The Paul Ehrlich Institute (German: ''Paul-Ehrlich-Institut – Bundesinstitut für Impfstoffe und biomedizinische Arzneimittel'', PEI) is a German federal agency, medical regulatory body and research institution for vaccines and biomedicines. It was founded in 1896 and is subordinate to the Federal Ministry of Health. The institute is a WHO Collaborating Centre for quality assurance of blood products and ''in vitro'' diagnostic devices. It is located in Langen, Hesse, near Frankfurt, and was located in Frankfurt for most of the 20th century. It is named for its founding director, the immunologist and Nobel Prize laureate Paul Ehrlich. History The Paul Ehrlich Institute was founded on 1 June 1896 in Steglitz, Berlin as the Institute for Serum Research and Serum Testing (Institut für Serumforschung und Serumprüfung), with immunologist Paul Ehrlich, one of Germany's most prominent medical researchers at the time, as its first director. The institute was founded specifically to p ...
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Johannes Löwer
Johannes Löwer (born 20 November 1944 in Vienna) is an Austrian/German biochemist and physician, who served as President of the Paul Ehrlich Institute from 1999 to 2009 and as President of the Federal Institute for Drugs and Medical Devices from 2009 to 2010. He studied medicine in Würzburg and Tübingen, earned a doctorate in medicine in 1970 and then went on to study biochemistry; he earned a master's degree in biochemistry in 1975 and a Habilitation in medical virology at the Goethe University Frankfurt Goethe University (german: link=no, Johann Wolfgang Goethe-Universität Frankfurt am Main) is a university located in Frankfurt am Main, Germany. It was founded in 1914 as a citizens' university, which means it was founded and funded by the wealt ... in 1990. He joined the Paul Ehrlich Institute as a scientist in 1981, and headed the department of virology from 1988 to 1991. In 1991 he became the Institute's vice president; he became acting president 1999 and was formally a ...
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Reinhard Kurth
Reinhard is a German, Austrian, Danish, and to a lesser extent Norwegian surname (from Germanic ''ragin'', counsel, and ''hart'', strong), and a spelling variant of Reinhardt. Persons with the given name * Reinhard of Blankenburg (after 1107 – 1123), German bishop *Reinhard Böhler (1945–1995), German sidecarcross racer *Reinhard Bonnke (1940–2019), German evangelist *Rainhard Fendrich (born 1955), Austrian singer *Reinhard Gehlen (1902–1979), German spymaster *Reinhard Heydrich (1904–1942), German Nazi leader *Reinhard Mey (born 1942), German singer *Reinhard Mohn (1921–2009), German media tycoon * Reinhard Odendaal (born 1980), South African award-winning winemaker *Reinhard Scheer (1863–1928), German admiral *Reinhard Selten (1930–2016), German economist *Reinhard Strohm (born 1942), German musicologist * Reinhard Stupperich (born 1951), German classical archaeologist * Reinhard Wendemuth (born 1948), German rower Persons with the surname *Blaire Rein ...
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Niels Kaj Jerne
Niels Kaj Jerne, FRS (23 December 1911 – 7 October 1994) was a Danish immunologist. He shared the Nobel Prize in Physiology or Medicine in 1984 with Georges J. F. Köhler and César Milstein "for theories concerning the specificity in development and control of the immune system and the discovery of the principle for production of monoclonal antibodies". Jerne is known for three significant ideas. Firstly, instead of the body producing antibodies in response to an antigen, Jerne postulated that the immune system already has the specific antibodies it needs to fight antigens. Secondly, it was known that the immune system learns to be tolerant to the individual's own self. Jerne postulated that this learning takes place in the thymus. Thirdly, it was known that T cells and B cells communicate with each other. Jerne's network theory proposed that the active sites of antibodies are attracted to both specific antigens (idiotypes) and to other antibodies that bind to the same ...
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Richard Prigge
Richard is a male given name. It originates, via Old French, from Old Frankish and is a compound of the words descending from Proto-Germanic ''*rīk-'' 'ruler, leader, king' and ''*hardu-'' 'strong, brave, hardy', and it therefore means 'strong in rule'. Nicknames include "Richie", "Dick", "Dickon", " Dickie", "Rich", "Rick", "Rico", "Ricky", and more. Richard is a common English, German and French male name. It's also used in many more languages, particularly Germanic, such as Norwegian, Danish, Swedish, Icelandic, and Dutch, as well as other languages including Irish, Scottish, Welsh and Finnish. Richard is cognate with variants of the name in other European languages, such as the Swedish "Rickard", the Catalan "Ricard" and the Italian "Riccardo", among others (see comprehensive variant list below). People named Richard Multiple people with the same name * Richard Andersen (other) * Richard Anderson (other) * Richard Cartwright (other) * Ri ...
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Richard Otto (physician)
Richard Ernst Wilhelm Otto (9 November 1872 – 12 August 1952) was a German physician and bacteriologist, who served as director of the Paul Ehrlich Institute until 1948. Career Otto was born in Zimmerhausen. He obtained his doctorate in medicine in 1895 and served as a military physician at the Prussian Institute of Infectious Diseases in Berlin from 1902. He was promoted to captain in 1903. From 1904 to 1907 he worked at the Royal Institute for Experimental Therapy in Frankfurt. He was appointed as a Professor in 1906 and became a battalion physician and director of the bacteriological laboratory of the Army Medical Service in Hanover in 1907. From 1908 he taught at the Technical University of Hanover. He was promoted to major and left active military service in 1913. From 1913 he again worked at the Institute of Infectious Diseases. He was appointed Geheimer Medizinalrat (equivalent to Geheimrat, i.e. Privy Councillor) in 1918 and was promoted to Lieutenant-Colonel of th ...
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Wilhelm Kolle
Wilhelm Kolle (born 2 November 1868 in Lerbach, Osterode am Harz, Lerbach near Osterode am Harz, died 10 May 1935) was a German bacteriologist and hygienist. He served as the second director of the Paul Ehrlich Institute, Royal Institute for Experimental Therapy, succeeding its founder, the Nobel laureate Paul Ehrlich. He was also the original author, with Heinrich Hetsch, of the famous book ''Experimental Bacteriology'', one of the most authoritative works in microbiology in the first half of the 20th century. Following studies of medicine at the universities of University of Göttingen, Göttingen, University of Halle, Halle and University of Würzburg, Würzburg, he became an assistant to Robert Koch at the ''Institut für Infektionskrankheiten'' (Institute for Infectious Diseases) in Berlin (1893–97). In 1897–98 he performed research of rinderpest and leprosy in South Africa, and in 1900, on behalf of the Egyptian government, studied rinderpest in Sudan. In 1901 he became de ...
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