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Patrick McGeer
Patrick Lucey McGeer (June 29, 1927 – August 29, 2022) was a Canadian physician, professor and medical researcher. He was regarded as a leading authority on the causes and prevention of Alzheimer's disease and was the principal author of the inflammatory hypothesis of the disease, which holds that Alzheimer's is an inflammation of the cortex. He was also a Canadian basketball player who competed in the 1948 Summer Olympics, a politician who represented the constituency of Vancouver-Point Grey in the British Columbia legislature from 1962 to 1986, and a member of the British Columbia cabinet from 1976 to 1986. In 1995, he and his wife Edith were inducted as Officers of the Order of Canada. In 2002 they were jointly inducted as Fellows of the Royal Society of Canada, and in 2005 they were jointly inducted into the Order of British Columbia. McGeer died at his home in Vancouver on August 29, 2022 at the age of 95. Aurin Biotech In August 2012, McGeer and his wife Edith found ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vancouver-Point Grey
Vancouver-Point Grey is a provincial electoral district for the Legislative Assembly of British Columbia, Canada. It was first contested in the general election of 1933. It was created out of parts of Richmond-Point Grey, South Vancouver and Vancouver City. The riding began as a three-member seat, and was reduced to a two-member seat in 1966 when Vancouver-Little Mountain was created. In the redistribution preceding the 1991 election, it was reduced to a one-member riding along with the other older urban ridings, as several new one-member ridings were created. Many prominent politicians have been elected as members, including three British Columbia premiers, Liberals Christy Clark and Gordon Campbell, and New Democrat incumbent premier David Eby. Former prime minister of Canada Kim Campbell also represented this riding. Geography The district currently comprises the Vancouver neighbourhoods of West Point Grey and the western part of Kitsilano, as well as the adjacent Un ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1948 Summer Olympics
The 1948 Summer Olympics (officially the Games of the XIV Olympiad and also known as London 1948) were an international multi-sport event held from 29 July to 14 August 1948 in London, England, United Kingdom. Following a twelve-year hiatus caused by the outbreak of World War II, these were the first Summer Olympics held since the 1936 Summer Olympics, 1936 Games in Berlin. The 1940 Summer Olympics, 1940 Olympic Games had been scheduled for Tokyo and then for Helsinki, while the 1944 Summer Olympics, 1944 Olympic Games had been provisionally planned for London. This was the second time London had hosted the Olympic Games, having previously hosted them in 1908 Summer Olympics, 1908, forty years earlier. The Olympics would again return to London 64 years later in 2012 Summer Olympics, 2012, making London the first city to have hosted the games three times, and the only such city until Paris and Los Angeles host their third games in 2024 Summer Olympics, 2024 and 2028 Summer Olympi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Basketball People From British Columbia
Basketball is a team sport in which two teams, most commonly of five players each, opposing one another on a rectangular court, compete with the primary objective of shooting a basketball (approximately in diameter) through the defender's hoop (a basket in diameter mounted high to a backboard at each end of the court, while preventing the opposing team from shooting through their own hoop. A field goal is worth two points, unless made from behind the three-point line, when it is worth three. After a foul, timed play stops and the player fouled or designated to shoot a technical foul is given one, two or three one-point free throws. The team with the most points at the end of the game wins, but if regulation play expires with the score tied, an additional period of play (overtime) is mandated. Players advance the ball by bouncing it while walking or running (dribbling) or by passing it to a teammate, both of which require considerable skill. On offense, players may use a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Basketball Players At The 1948 Summer Olympics
Basketball is a team sport in which two teams, most commonly of five players each, opposing one another on a rectangular court, compete with the primary objective of shooting a basketball (approximately in diameter) through the defender's hoop (a basket in diameter mounted high to a backboard at each end of the court, while preventing the opposing team from shooting through their own hoop. A field goal is worth two points, unless made from behind the three-point line, when it is worth three. After a foul, timed play stops and the player fouled or designated to shoot a technical foul is given one, two or three one-point free throws. The team with the most points at the end of the game wins, but if regulation play expires with the score tied, an additional period of play (overtime) is mandated. Players advance the ball by bouncing it while walking or running (dribbling) or by passing it to a teammate, both of which require considerable skill. On offense, players may use a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
2022 Deaths
The following notable deaths occurred in 2022. Names are reported under the date of death, in alphabetical order. A typical entry reports information in the following sequence: * Name, age, country of citizenship at birth, subsequent nationality (if applicable), what subject was noted for, cause of death (if known), and reference. December 25 * Chalapathi Rao, 78, Indian actor and producer, heart attack. (death announced on this date) 24 *Vittorio Adorni, 85, Italian road racing cyclist. *Cotton Davidson, 91, American football player ( Baltimore Colts, Dallas Texans, Oakland Raiders). (death announced on this date) *Franco Frattini, 65, Italian politician and magistrate, twice minister of foreign affairs, twice of public administration, European commissioner for justice (2004–2008), cancer. *Madosini, 78, South African musician. *Barry Round, 72, Australian footballer (Sydney, Footscray, Williamstown), organ failure. *Royal Applause, 29, British Thoroughbred racehorse ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1927 Births
Nineteen or 19 may refer to: * 19 (number), the natural number following 18 and preceding 20 * one of the years 19 BC, AD 19, 1919, 2019 Films * ''19'' (film), a 2001 Japanese film * ''Nineteen'' (film), a 1987 science fiction film Music * 19 (band), a Japanese pop music duo Albums * ''19'' (Adele album), 2008 * ''19'', a 2003 album by Alsou * ''19'', a 2006 album by Evan Yo * ''19'', a 2018 album by MHD * ''19'', one half of the double album ''63/19'' by Kool A.D. * ''Number Nineteen'', a 1971 album by American jazz pianist Mal Waldron * ''XIX'' (EP), a 2019 EP by 1the9 Songs * "19" (song), a 1985 song by British musician Paul Hardcastle. * "Nineteen", a song by Bad4Good from the 1992 album '' Refugee'' * "Nineteen", a song by Karma to Burn from the 2001 album ''Almost Heathen''. * "Nineteen" (song), a 2007 song by American singer Billy Ray Cyrus. * "Nineteen", a song by Tegan and Sara from the 2007 album '' The Con''. * "XIX" (song), a 2014 song by Slipk ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Aurintricarboxylic Acid
Aurintricarboxylic acid (ATA) is a chemical compound that readily polymerizes in aqueous solution, forming a stable free radical that inhibits protein-nucleic acid interactions. It is a potent inhibitor of ribonuclease and topoisomerase II by preventing the binding of the nucleic acid to the enzyme. It stimulates tyrosine phosphorylation processes including the Jak2/STAT5 pathway in NB2 lymphoma cells, ErbB4 in neuroblastoma cells, and MAP kinases, Shc proteins, phosphatidylinositide 3-kinase and phospholipase Cγ in PC12 cells. It also inhibits apoptosis. It prevents down-regulation of Ca2+-impermeable GluR2 receptors and inhibits calpain, a Ca2+-activated protease that is activated during apoptosis. It is used to inhibit protein biosynthesis in its initial stages. Nominally, it is used in biological experiments as a protein inhibitor, and as an ammonium salt (known as aluminon) it is used as a reagent to estimate the aluminium in water, biological tissue, and foods. It was ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Complement System
The complement system, also known as complement cascade, is a part of the immune system that enhances (complements) the ability of antibodies and phagocytic cells to clear microbes and damaged cells from an organism, promote inflammation, and attack the pathogen's cell membrane. It is part of the innate immune system, which is not adaptable and does not change during an individual's lifetime. The complement system can, however, be recruited and brought into action by antibodies generated by the adaptive immune system. The complement system consists of a number of small proteins that are synthesized by the liver, and circulate in the blood as inactive precursors. When stimulated by one of several triggers, proteases in the system cleave specific proteins to release cytokines and initiate an amplifying cascade of further cleavages. The end result of this ''complement activation'' or ''complement fixation'' cascade is stimulation of phagocytes to clear foreign and damaged material ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Aurintricarboxylic Acid
Aurintricarboxylic acid (ATA) is a chemical compound that readily polymerizes in aqueous solution, forming a stable free radical that inhibits protein-nucleic acid interactions. It is a potent inhibitor of ribonuclease and topoisomerase II by preventing the binding of the nucleic acid to the enzyme. It stimulates tyrosine phosphorylation processes including the Jak2/STAT5 pathway in NB2 lymphoma cells, ErbB4 in neuroblastoma cells, and MAP kinases, Shc proteins, phosphatidylinositide 3-kinase and phospholipase Cγ in PC12 cells. It also inhibits apoptosis. It prevents down-regulation of Ca2+-impermeable GluR2 receptors and inhibits calpain, a Ca2+-activated protease that is activated during apoptosis. It is used to inhibit protein biosynthesis in its initial stages. Nominally, it is used in biological experiments as a protein inhibitor, and as an ammonium salt (known as aluminon) it is used as a reagent to estimate the aluminium in water, biological tissue, and foods. It was ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Order Of British Columbia
The Order of British Columbia (french: Ordre de la Colombie-Britannique) is a civilian honour for merit in the Canadian province of British Columbia. Instituted in 1989 by Lieutenant Governor David Lam, on the advice of the Cabinet under Premier Bill Vander Zalm, the order is administered by the Governor-in-Council and is intended to honour current or former British Columbia residents for conspicuous achievements in any field, being thus described as the highest honour amongst all others conferred by the British Columbia Crown. Structure and appointment The Order of British Columbia, which evolved out of and replaced the earlier Order of the Dogwood, is intended to honour any current or former longtime resident of British Columbia who has demonstrated a high level of individual excellence and achievement in any field, demonstrating the "greatest distinction and excell ncein any field of endeavour benefiting the people of the Province or elsewhere." Only those who are elected or ap ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Royal Society Of Canada
The Royal Society of Canada (RSC; french: Société royale du Canada, SRC), also known as the Academies of Arts, Humanities and Sciences of Canada (French: ''Académies des arts, des lettres et des sciences du Canada''), is the senior national, bilingual council of distinguished Canadian scholars, humanists, scientists and artists. The primary objective of the RSC is to promote learning and research in the arts, the humanities and the sciences. The RSC is Canada's National Academy and exists to promote Canadian research and scholarly accomplishment in both official languages, to recognize academic and artistic excellence, and to advise governments, non-governmental organizations and Canadians on matters of public interest. History In the late 1870s, the Governor General of Canada, the Marquis of Lorne, determined that Canada required a cultural institution to promote national scientific research and development. Since that time, succeeding Governor Generals have remained involved w ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Order Of Canada
The Order of Canada (french: Ordre du Canada; abbreviated as OC) is a Canadian state order and the second-highest honour for merit in the system of orders, decorations, and medals of Canada, after the Order of Merit. To coincide with the centennial of Canadian Confederation, the three-tiered order was established in 1967 as a fellowship that recognizes the outstanding merit or distinguished service of Canadians who make a major difference to Canada through lifelong contributions in every field of endeavour, as well as the efforts by non-Canadians who have made the world better by their actions. Membership is accorded to those who exemplify the order's Latin motto, , meaning "they desire a better country", a phrase taken from Hebrews 11:16. The three tiers of the order are Companion, Officer, and Member; specific individuals may be given extraordinary membership and deserving non-Canadians may receive honorary appointment into each grade. , the reigning Canadian monarch, is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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