Parinaud's Oculoglandular Syndrome
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Parinaud's Oculoglandular Syndrome
Parinaud's oculoglandular syndrome (POS) is a medical condition characterized by a specific set of symptoms affecting the eye and nearby lymph nodes. Named after the French ophthalmologist Henri Parinaud, it should not be confused with the neurological syndrome caused by a lesion in the midbrain which is also known as Parinaud's syndrome. Both were named after the same person, Henri Parinaud. Signs and symptoms The syndrome manifests as granulomatous conjunctivitis in one eye, accompanied by swollen lymph nodes in front of the ear on the same side. Granulomatous conjunctivitis refers to inflammation of the conjunctiva, the membrane that covers the white part of the eye, characterized by the presence of granulomas, small areas of inflammation due to tissue injury. Patients with POS may experience a red, irritated, and painful eye, fever, a general lack of well-being, swelling of nearby lymph glands, and sometimes increased tearing.Mannis, MJ, and Holland, EJ. **Cornea**. 5th ed. Els ...
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Parinaud's Syndrome
Parinaud's syndrome is an inability to move the eyes up and down. It is caused by compression of the vertical gaze center at the rostral interstitial nucleus of medial longitudinal fasciculus (riMLF). The eyes lose the ability to move upward and down. It is a group of abnormalities of eye movement and pupil dysfunction. It is caused by lesions of the upper brain stem and is named for Henri Parinaud (1844–1905), considered to be the father of French ophthalmology. Signs and symptoms Parinaud's syndrome is a cluster of abnormalities of eye movement and pupil dysfunction, characterized by: * Paralysis of upwards gaze: Downward gaze is usually preserved. This vertical palsy is supranuclear, so doll's head maneuver should elevate the eyes, but eventually all upward gaze mechanisms fail. * Pseudo- Argyll Robertson pupils: Accommodative paresis ensues, and pupils become mid-dilated and show light-near dissociation. * Convergence-retraction nystagmus: Attempts at upward gaze often p ...
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Henri Parinaud
Henri Parinaud (1 May 1844, Bellac – 23 March 1905,Henri Parinaud
at Who Named It ) was a French ophthalmologist and , most noted for his work in the field of .


Early life

Henri Parinaud was born into a lower-class family in 1844, and his father died when Henri was 19. He went on to study medicine at
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Bartonella Henselae
''Bartonella henselae'', formerly ''Rochalimæa henselae'', is a bacterium that is the causative agent of cat-scratch disease ( bartonellosis). ''Bartonella henselae'' is a member of the genus ''Bartonella'', one of the most common types of bacteria in the world. It is a facultative intracellular microbe that targets red blood cells. One study showed it invaded the mature blood cells of humans. It infects the host cell by sticking to it using trimeric autotransporter adhesins. In the United States, about 22,000 people(per year?)are diagnosed, most under the age of 20. Most often, it is transmitted from kittens. Diagnosis ''Bartonella henselae'' is a Gram-negative rod. It can be cultured in a lysis-centrifugation blood culture. The presence of bacteria can be detected by Warthin-Starry stain, or by a similar silver stain technique performed on infected tissue. The specific name ''henselae'' honors Diane Marie Hensel (b. 1953), a clinical microbiology technologist at University ...
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Francisella Tularensis
''Francisella tularensis'' is a pathogenic species of Gram-negative coccobacillus, an aerobic bacterium. It is nonspore-forming, nonmotile, and the causative agent of tularemia, the pneumonic form of which is often lethal without treatment. It is a fastidious, facultative intracellular bacterium, which requires cysteine for growth. Due to its low infectious dose, ease of spread by aerosol, and high virulence, ''F. tularensis'' is classified as a Tier 1 Select Agent by the U.S. government, along with other potential agents of bioterrorism such as ''Yersinia pestis, Bacillus anthracis'', and Ebola virus. When found in nature, ''Francisella tularensis'' can survive for several weeks at low temperatures in animal carcasses, soil, and water. In the laboratory, ''F. tularensis'' appears as small rods (0.2 by 0.2 µm), and is grown best at 35–37 °C. History This species was discovered in ground squirrels in Tulare County, California in 1911. ''Bacterium tularense'' was soon ...
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Herpes Simplex Virus
Herpes simplex virus 1 and 2 (HSV-1 and HSV-2), also known by their taxonomical names ''Human alphaherpesvirus 1'' and '' Human alphaherpesvirus 2'', are two members of the human ''Herpesviridae'' family, a set of viruses that produce viral infections in the majority of humans. Both HSV-1 and HSV-2 are very common and contagious. They can be spread when an infected person begins shedding the virus. As of 2016, about 67% of the world population under the age of 50 had HSV-1. In the United States, about 47.8% and 11.9% are estimated to have HSV-1 and HSV-2, respectively, though actual prevalence may be much higher. Because it can be transmitted through any intimate contact, it is one of the most common sexually transmitted infections. Symptoms Many of those who are infected ''never'' develop symptoms. Symptoms, when they occur, may include watery blisters in the skin or mucous membranes of the mouth, lips, nose, genitals, or eyes (herpes simplex keratitis). Lesions heal with a ...
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Paracoccidioides Brasiliensis
''Paracoccidioides brasiliensis'' is a dimorphic fungus and one of the two species that cause paracoccidioidomycosis (the other being ''Paracoccidioides lutzii).'' The fungus has been affiliated with the family Ajellomycetaceae (division Ascomycota) although a sexual state or teleomorph has not yet been found. History ''Paracoccidioides brasiliensis'' was first discovered by Adolfo Lutz in 1908 in Brazil. Although Lutz did not suggest a name for the disease caused by this fungus, he made note of structures he called "pseudococcidica" together with mycelium in cultures grown at 25 °C. In 1912, Alfonse Splendore proposed the name ''Zymonema brasiliense'' and described the features of the fungus in culture. Finally in 1930, Floriano de Almeida created the genus ''Paracoccidioides'' to accommodate the species, noting its distinction from ''Coccidioides immitis''. Physiology ''Paracoccidioides brasiliensis'' is a nonphotosynthetic eukaryote with a rigid cell wall and organelles ...
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American Academy Of Ophthalmology
The American Academy of Ophthalmology (Academy) is a professional medical association of ophthalmologists. It is headquartered in San Francisco, California. Its membership of 32,000 medical doctors includes more than 90 percent of practicing ophthalmologists in the United States as well as over 7,000 members abroad. The Academy's stated mission is "to protect sight and empower lives by serving as an advocate for patients and the public, leading ophthalmic education, and advancing the profession of ophthalmology." History The academy has its origins in the American Academy of Ophthalmology and Otolaryngology (AAOO), founded in 1896 as a medical association of both ophthalmologists and otolaryngologists. The Academy was founded when the AAOO split in 1979 and divided into separate academies for each specialty. Like most medical associations, the Academy collects dues, provides continuing education and seminars for its members, including its four-day annual meeting. Outside the ...
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Infectious Diseases
An infection is the invasion of tissues by pathogens, their multiplication, and the reaction of host tissues to the infectious agent and the toxins they produce. An infectious disease, also known as a transmissible disease or communicable disease, is an illness resulting from an infection. Infections can be caused by a wide range of pathogens, most prominently bacteria and viruses. Hosts can fight infections using their immune system. Mammalian hosts react to infections with an innate response, often involving inflammation, followed by an adaptive response. Specific medications used to treat infections include antibiotics, antivirals, antifungals, antiprotozoals, and antihelminthics. Infectious diseases resulted in 9.2 million deaths in 2013 (about 17% of all deaths). The branch of medicine that focuses on infections is referred to as infectious disease. Types Infections are caused by infectious agents (pathogens) including: * Bacteria (e.g. ''Mycobacterium tuberculosis'' ...
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Herpes Simplex Virus–associated Diseases
Herpes simplex is a viral infection caused by the herpes simplex virus. Infections are categorized based on the part of the body infected. Oral herpes involves the face or mouth. It may result in small blisters in groups often called cold sores or fever blisters or may just cause a sore throat. Genital herpes, often simply known as herpes, involves the genitalia. It may have minimal symptoms or form blisters that break open and result in small ulcers. These typically heal over two to four weeks. Tingling or shooting pains may occur before the blisters appear. Herpes cycles between periods of active disease followed by periods without symptoms. The first episode is often more severe and may be associated with fever, muscle pains, swollen lymph nodes and headaches. Over time, episodes of active disease decrease in frequency and severity. Herpetic whitlow typically involves the fingers or thumb. Herpes simplex keratitis involves the eye. Herpesviral encephalitis involves the ...
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