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Paragroup
Paragroup is a term used in population genetics to describe lineages within a haplogroup that are not defined by any additional unique markers. In human Y-chromosome DNA haplogroups, paragroups are typically represented by an asterisk (*) placed after the main haplogroup. The term "paragroup" is a portmanteau of the terms paraphyletic haplogroup A haplotype is a group of alleles in an organism that are inherited together from a single parent, and a haplogroup (haploid from the el, ἁπλοῦς, ''haploûs'', "onefold, simple" and en, group) is a group of similar haplotypes that share ... indicating that paragroups form paraphyletic subclades. Apart from the mutations that define the parent haplogroup, paragroups may not possess any additional unique markers. Alternatively paragroups may possess unique markers that have not been discovered. If a unique marker is discovered within a paragroup, the specific lineage is given a unique name and is moved out of the paragroup to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
E1b1b
E-M215, also known as E1b1b and formerly E3b, is a major human Y-chromosome DNA haplogroup. It is a division of the macro-haplogroup E-M96, which is defined by the single-nucleotide polymorphism (SNP) mutation M215. In other words, it is one of the major patrilineality, patrilineages of humanity, linking from father-to-son back to a common male-line ancestor ("Y-chromosomal Adam"). It is a subject of discussion and study in genetics as well as genetic genealogy, archaeology, and historical linguistics. The E-M215 haplogroup has two ancient branches that contain all the known modern E-M215, E-M35 and E-M281 subclades. Of the latter two E-M215 subhaplogroups, the only branch that has been confirmed in a native population outside of Ethiopia is E-M35. E-M35 in turn has two known branches, Haplogroup E-V68, E-V68 and Haplogroup E-Z827, E-Z827, which contain by far the majority of all modern E-M215 subclade bearers. The E-V257 and E-V68 subclades each respectively their highest freque ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Haplogroup E (Y-DNA)
Haplogroup E-M96 is a human Y-chromosome DNA haplogroup. It is one of the two main branches of the older and ancestral haplogroup DE, the other main branch being haplogroup D. The E-M96 clade is divided into two main subclades: the more common E-P147, and the less common E-M75. Origins Underhill (2001) proposed that haplogroup E may have arisen in East Africa. Some authors as Chandrasekar (2007), accept the earlier position of Hammer (1997) that Haplogroup E may have originated in West Asia, given that: * E is a clade of Haplogroup DE, with the other major clade, haplogroup D, being exclusively distributed in Asia. * DE is a clade within M168 with the other two major clades, C and F, considered to have already a Eurasian origin. However, several discoveries made since the Hammer articles are thought to make an Asian origin less likely: # Underhill and Kivisild (2007) demonstrated that C and F have a common ancestor meaning that DE has only one sibling which is non-Africa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Haplogroup D-M174 (Y-DNA)
Haplogroup D1 or D-M174 is a subclade of Haplogroup D-CTS3946. This male haplogroup is found primarily in East Asia and the Andaman Islands, though it is also found regularly with low frequency in Central Asia and Mainland Southeast Asia. It's also found as far as Europe and Middle east in lower frequencies. Origins Haplogroup D-M174 is believed to have originated in Asia some 60,000 years before present. While haplogroup D-M174 along with haplogroup E contains the distinctive YAP polymorphism (which indicates their closer ancestry than C), no haplogroup D-M174 chromosomes have been found anywhere outside of Asia. Haplogroup D1 is also often associated with "Southern Asian" populations. Several studies (Hammer et al. 2006, Shinoda 2008, Matsumoto 2009, Cabrera et al. 2018) suggest that the paternal haplogroup D-M174 originated somewhere in Central Asia. According to Hammer et al., haplogroup D-M174 originated between Tibet and the Altai mountains. He suggests that there were ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Haplogroup DE (Y-DNA)
Haplogroup DE is a human Y-chromosome DNA haplogroup. It is defined by the single nucleotide polymorphism (SNP) mutations, or UEPs, M1(YAP), M145(P205), M203, P144, P153, P165, P167, P183. DE is unique because it is distributed in several geographically distinct clusters. An immediate subclade, haplogroup D (also known as D-CTS3946), is mainly found in East Asia, parts of Central Asia, and the Andaman Islands, but also sporadically in West Africa and West Asia. The other immediate subclade, haplogroup E, is common in Africa, and to a lesser extent the Middle East and southern Europe. The most well-known unique event polymorphism (UEP) that defines DE is the Y-chromosome Alu Polymorphism "YAP''"''. The mutation was caused when a strand of DNA, known as Alu, inserted a copy of itself into the Y chromosome. Hence, all Y chromosomes belonging to DE, D, E and their subclades are YAP-positive (YAP+). All Y chromosomes that belong to other haplogroups and subclades are YAP-negative ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Haplogroup R (Y-DNA)
Haplogroup R, or R-M207, is a Y-chromosome DNA haplogroup. It is both numerous and widespread amongst modern populations. Some descendant subclades have been found since pre-history in Europe, Central Asia and South Asia. Others have long been present, at lower levels, in parts of West Asia and Africa. Some authorities have also suggested, more controversially, that R-M207 has long been present among Native Americans in North America – a theory that has not yet been widely accepted. According to geneticist Spencer Wells, haplogroup K, from which haplogroups P and Q descend, originated in the Middle East or Central Asia. "Given the widespread distribution of K, it probably arose somewhere in the Middle East or Central Asia, perhaps in the region of Iran or Pakistan." However, Karafet et al. (2014) proposed that "rapid diversification ... of K-M526", also known as K2, likely occurred in Southeast Asia (near Indonesia) and later expanded to mainland Asia, although they could ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Population Genetics
Population genetics is a subfield of genetics that deals with genetic differences within and between populations, and is a part of evolutionary biology. Studies in this branch of biology examine such phenomena as Adaptation (biology), adaptation, speciation, and population stratification, population structure. Population genetics was a vital ingredient in the emergence of the Modern synthesis (20th century), modern evolutionary synthesis. Its primary founders were Sewall Wright, J. B. S. Haldane and Ronald Fisher, who also laid the foundations for the related discipline of quantitative genetics. Traditionally a highly mathematical discipline, modern population genetics encompasses theoretical, laboratory, and field work. Population genetic models are used both for statistical inference from DNA sequence data and for proof/disproof of concept. What sets population genetics apart from newer, more phenotypic approaches to modelling evolution, such as evolutionary game theory and evo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Haplogroup
A haplotype is a group of alleles in an organism that are inherited together from a single parent, and a haplogroup (haploid from the el, ἁπλοῦς, ''haploûs'', "onefold, simple" and en, group) is a group of similar haplotypes that share a common ancestor with a single-nucleotide polymorphism mutation. More specifically, a haplogroup is a combination of alleles at different chromosomal regions that are closely linked and that tend to be inherited together. As a haplogroup consists of similar haplotypes, it is usually possible to predict a haplogroup from haplotypes. Haplogroups pertain to a single line of descent. As such, membership of a haplogroup, by any individual, relies on a relatively small proportion of the genetic material possessed by that individual. Each haplogroup originates from, and remains part of, a preceding single haplogroup (or paragroup). As such, any related group of haplogroups may be precisely modelled as a nested hierarchy, in which each set (ha ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Unique-event Polymorphism
In genetic genealogy, a unique-event polymorphism (UEP) is a genetic marker that corresponds to a mutation that is likely to occur so infrequently that it is believed overwhelmingly probable that all the individuals who share the marker, worldwide, will have inherited it from the same common ancestor, and the same single mutation event. Generally, UEP is an allele for which all copies derive from a single mutational event. In genetic genealogy, the mutations considered to be UEPs can be any germline mutation. They are usually single-nucleotide polymorphisms (SNP) – the replacement of one letter by another in the DNA sequence, and the terms UEP and SNP are often loosely used interchangeably. But UEPs may also be large-scale additions, such as the YAP insertion that defines Y-DNA haplogroup DE, inversions or deletions. The discovery and widespread testing of new UEPs has been the key to the increasingly detailed analysis of the patrilineal and matrilineal ancestry of mank ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Human Y-chromosome DNA Haplogroup
In human genetics, a human Y-chromosome DNA haplogroup is a haplogroup defined by mutations in the non- recombining portions of DNA from the male-specific Y chromosome (called Y-DNA). Many people within a haplogroup share similar numbers of short tandem repeats (STRs) and types of mutations called single-nucleotide polymorphisms (SNPs). The human Y-chromosome accumulates roughly two mutations per generation. "one mutation in every 30 million base pairs" Y-DNA haplogroups represent major branches of the Y-chromosome phylogenetic tree that share hundreds or even thousands of mutations unique to each haplogroup. The Y-chromosomal most recent common ancestor (Y-MRCA, informally known as Y-chromosomal Adam) is the most recent common ancestor (MRCA) from whom all currently living humans are descended patrilineally. Y-chromosomal Adam is estimated to have lived roughly 236,000 years ago in Africa. By examining other bottlenecks most Eurasian men (men from populations outside ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Asterisk
The asterisk ( ), from Late Latin , from Ancient Greek , ''asteriskos'', "little star", is a typographical symbol. It is so called because it resembles a conventional image of a heraldic star. Computer scientists and mathematicians often vocalize it as star (as, for example, in ''the A* search algorithm'' or '' C*-algebra''). In English, an asterisk is usually five- or six-pointed in sans-serif typefaces, six-pointed in serif typefaces, and six- or eight-pointed when handwritten. Its most common use is to call out a footnote. It is also often used to censor offensive words. In computer science, the asterisk is commonly used as a wildcard character, or to denote pointers, repetition, or multiplication. History The asterisk has already been used as a symbol in ice age cave paintings. There is also a two thousand-year-old character used by Aristarchus of Samothrace called the , , which he used when proofreading Homeric poetry to mark lines that were duplicated. Origen is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Portmanteau
A portmanteau word, or portmanteau (, ) is a blend of wordsGarner's Modern American Usage , p. 644. in which parts of multiple words are combined into a new word, as in ''smog'', coined by blending ''smoke'' and ''fog'', or ''motel'', from ''motor'' and ''hotel''. In , a portmanteau is a single morph that is analyzed as representing two (or more) underlying morphemes. When portmanteaus shorten established [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Paraphyletic
In taxonomy, a group is paraphyletic if it consists of the group's last common ancestor and most of its descendants, excluding a few monophyletic subgroups. The group is said to be paraphyletic ''with respect to'' the excluded subgroups. In contrast, a monophyletic group (a clade) includes a common ancestor and ''all'' of its descendants. The terms are commonly used in phylogenetics (a subfield of biology) and in the tree model of historical linguistics. Paraphyletic groups are identified by a combination of synapomorphies and symplesiomorphies. If many subgroups are missing from the named group, it is said to be polyparaphyletic. The term was coined by Willi Hennig to apply to well-known taxa like Reptilia ( reptiles) which, as commonly named and traditionally defined, is paraphyletic with respect to mammals and birds. Reptilia contains the last common ancestor of reptiles and all descendants of that ancestor, including all extant reptiles as well as the extinct synaps ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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