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PPP4C
Serine/threonine-protein phosphatase 4 catalytic subunit is an enzyme that in humans is encoded by the ''PPP4C'' gene. Interactions PPP4C has been shown to interact with: * CCDC6, * CCT2, * CCT3, * CCT4, * CCT5, * CCT6A, * CCT7, * IGBP1, * PPP2R1A, * PPP4R1, * REL, * SMEK2, * T-complex 1, and * TRAF6 TRAF6 is a TRAF human protein. Function The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF recep .... References Further reading

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CCDC6
Coiled-coil domain-containing protein 6 is a protein that in humans is encoded by the ''CCDC6'' gene. Interactions CCDC6 has been shown to interact with PPP4C Serine/threonine-protein phosphatase 4 catalytic subunit is an enzyme that in humans is encoded by the ''PPP4C'' gene. Interactions PPP4C has been shown to interact with: * CCDC6, * CCT2, * CCT3, * CCT4, * CCT5, * CCT6A, * CCT7, * IG .... References External links * Further reading

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CCT2 (gene)
T-complex protein 1 subunit beta is a protein that in humans is encoded by the ''CCT2'' gene. Function This gene encodes a molecular chaperone that is member of the TRiC complex. This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of the gene described in this record have been observed but have not been thoroughly characterized. Interactions CCT2 (gene) has been shown to interact with PPP4C Serine/threonine-protein phosphatase 4 catalytic subunit is an enzyme that in humans is encoded by the ''PPP4C'' gene. Interactions PPP4C has been shown to interact with: * CCDC6, * CCT2, * CCT3, * CCT4, * CCT5, * CCT6A, * CCT7, * IG .... References External links * * Further reading

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CCT3
T-complex protein 1 subunit gamma is a protein that in humans is encoded by the ''CCT3'' gene. Function This gene encodes a molecular chaperone that is member of the TRiC complex. This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Interactions CCT3 has been shown to interact with PPP4C Serine/threonine-protein phosphatase 4 catalytic subunit is an enzyme that in humans is encoded by the ''PPP4C'' gene. Interactions PPP4C has been shown to interact with: * CCDC6, * CCT2, * CCT3, * CCT4, * CCT5, * CCT6A, * CCT7, * IG .... References External links * Further reading

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CCT4
T-complex protein 1 subunit delta is a protein that in humans is encoded by the ''CCT4'' gene. The CCT4 protein is a component of the TRiC complex. Interactions CCT4 has been shown to interact with PPP4C Serine/threonine-protein phosphatase 4 catalytic subunit is an enzyme that in humans is encoded by the ''PPP4C'' gene. Interactions PPP4C has been shown to interact with: * CCDC6, * CCT2, * CCT3, * CCT4, * CCT5, * CCT6A, * CCT7, * IG .... References External links * Further reading

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CCT5 (gene)
T-complex protein 1 subunit epsilon is a protein that in humans is encoded by the ''CCT5'' gene. Function This gene encodes a molecular chaperone that is member of the TRiC complex. This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. Interactions CCT5 (gene) has been shown to interact with PPP4C Serine/threonine-protein phosphatase 4 catalytic subunit is an enzyme that in humans is encoded by the ''PPP4C'' gene. Interactions PPP4C has been shown to interact with: * CCDC6, * CCT2, * CCT3, * CCT4, * CCT5, * CCT6A, * CCT7, * IG .... References External links * Further reading

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CCT6A
T-complex protein 1 subunit zeta is a protein that in humans is encoded by the ''CCT6A'' gene. Function This gene encodes a molecular chaperone that is member of the TRiC complex. This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. Interactions CCT6A has been shown to interact with PPP4C Serine/threonine-protein phosphatase 4 catalytic subunit is an enzyme that in humans is encoded by the ''PPP4C'' gene. Interactions PPP4C has been shown to interact with: * CCDC6, * CCT2, * CCT3, * CCT4, * CCT5, * CCT6A, * CCT7, * IG .... References External links * Further reading

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CCT7
T-complex protein 1 subunit eta is a protein that in humans is encoded by the ''CCT7'' gene. Function This gene encodes a molecular chaperone that is a member of the TRiC complex. This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants encoding different isoforms have been found for this gene, but only two of them have been characterized to date. Interactions CCT7 has been shown to interact with PPP4C Serine/threonine-protein phosphatase 4 catalytic subunit is an enzyme that in humans is encoded by the ''PPP4C'' gene. Interactions PPP4C has been shown to interact with: * CCDC6, * CCT2, * CCT3, * CCT4, * CCT5, * CCT6A, * CCT7, * IG .... References External links * Further reading

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IGBP1
Immunoglobulin-binding protein 1 is a protein that in humans is encoded by the ''IGBP1'' gene. Function The proliferation and differentiation of B cells is dependent upon a B-cell antigen receptor (BCR) complex. Binding of antigens to specific B-cell receptors results in a tyrosine phosphorylation reaction through the BCR complex and leads to multiple signal transduction pathways. Interactions IGBP1 has been shown to interact with PPP4C, PPP6C and PPP2CA Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform is an enzyme that (in humans) is encoded by the ''PPP2CA'' gene. Function This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the fou .... References Further reading

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PPP2R1A
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform is an enzyme that in humans is encoded by the ''PPP2R1A'' gene. In the plant Arabidopsis thaliana a similar enzyme is encoded by the RCN1 gene (At1g25490). Function This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes an alpha isoform of the constant regulatory subunit A. Interactions PPP2R1A has been shown to interact with: * CTTNBP2NL, * FAM40A, * PPP2CB, PPP2CA, PPP4C, * PPP2R2A, * P ...
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PPP4R1
Serine/threonine-protein phosphatase 4 regulatory subunit 1 is an enzyme that in humans is encoded by the ''PPP4R1'' gene. Interactions PPP4R1 has been shown to interact with PPP4C Serine/threonine-protein phosphatase 4 catalytic subunit is an enzyme that in humans is encoded by the ''PPP4C'' gene. Interactions PPP4C has been shown to interact with: * CCDC6, * CCT2, * CCT3, * CCT4, * CCT5, * CCT6A, * CCT7, * IG .... References Further reading

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SMEK2
Serine/threonine-protein phosphatase 4 regulatory subunit 3B is an enzyme that in humans is encoded by the ''SMEK2'' gene. Interactions SMEK2 has been shown to interact with PPP4C Serine/threonine-protein phosphatase 4 catalytic subunit is an enzyme that in humans is encoded by the ''PPP4C'' gene. Interactions PPP4C has been shown to interact with: * CCDC6, * CCT2, * CCT3, * CCT4, * CCT5, * CCT6A, * CCT7, * IG .... References Further reading

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T-complex 1
T-complex protein 1 subunit alpha is a protein that in humans is encoded by the ''TCP1'' gene. Function This gene encodes a molecular chaperone that is a member of the TRiC complex. This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. Interactions T-complex 1 has been shown to interact with PPP4C and HDAC3. CCT also directly interacts with lectin type oxidized LDL receptor-1 (LOX-1) while its ligand oxidized low density lipoprotein (OxLDL) disassociates CCT from LOX-1 Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1) also known as lectin-type oxidized LDL receptor 1 (LOX-1) is a protein that in humans is encoded by the ''OLR1'' gene. LOX-1 i ...
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