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Oxford Nanopore Technologies
Oxford Nanopore Technologies Limited is a UK-based company which is developing and selling nanopore sequencing products (including the portable DNA sequencer, MinION) for the direct, electronic analysis of single molecules. History The company was founded in 2005 as a spin-out from the University of Oxford by Hagan Bayley, Gordon Sanghera, and Spike Willcocks, with seed funding from the IP Group. By May 2021, over several rounds of investment, the company had privately raised over £990 million from leading investors including M&G Catalyst and Temasek. The company raised a further £350 million in its initial public offering on the London Stock Exchange on 30 September 2021, under the ticker LSE:ONT.L Products The main products of Oxford Nanopore are: * MinION: this portable protein nanopore sequencing USB device has been commercially available since May 2015 after having been launched initially through an early access programme, the MinION Access Programme (MAP). An edit ...
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Nanopore Sequencing
Nanopore sequencing is a third generation approach used in the sequencing of biopolymers — specifically, polynucleotides in the form of DNA or RNA. Using nanopore sequencing, a single molecule of DNA or RNA can be sequenced without the need for PCR amplification or chemical labeling of the sample. Nanopore sequencing has the potential to offer relatively low-cost genotyping, high mobility for testing, and rapid processing of samples with the ability to display results in real-time. Publications on the method outline its use in rapid identification of viral pathogens, monitoring ebola, environmental monitoring, food safety monitoring, human genome sequencing, plant genome sequencing, monitoring of antibiotic resistance, haplotyping and other applications. Development Nanopore sequencing took 25 years to fully materialize. It involved close collaboration between academia and industry. One of the first people to put forward the idea for nanopore sequencing was David D ...
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Small Molecule
Within the fields of molecular biology and pharmacology, a small molecule or micromolecule is a low molecular weight (≤ 1000 daltons) organic compound that may regulate a biological process, with a size on the order of 1 nm. Many drugs are small molecules; the terms are equivalent in the literature. Larger structures such as nucleic acids and proteins, and many polysaccharides are not small molecules, although their constituent monomers (ribo- or deoxyribonucleotides, amino acids, and monosaccharides, respectively) are often considered small molecules. Small molecules may be used as research tools to probe biological function as well as leads in the development of new therapeutic agents. Some can inhibit a specific function of a protein or disrupt protein–protein interactions. Pharmacology usually restricts the term "small molecule" to molecules that bind specific biological macromolecules and act as an effector, altering the activity or function of the target. Small ...
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Companies Based In Oxford
A company, abbreviated as co., is a Legal personality, legal entity representing an association of people, whether Natural person, natural, Legal person, legal or a mixture of both, with a specific objective. Company members share a common purpose and unite to achieve specific, declared goals. Companies take various forms, such as: * voluntary associations, which may include nonprofit organizations * List of legal entity types by country, business entities, whose aim is generating profit * financial entities and banks * programs or Educational institution, educational institutions A company can be created as a legal person so that the company itself has limited liability as members perform or fail to discharge their duty according to the publicly declared Incorporation (business), incorporation, or published policy. When a company closes, it may need to be Liquidation, liquidated to avoid further legal obligations. Companies may associate and collectively register themselves ...
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British Companies Established In 2005
British may refer to: Peoples, culture, and language * British people, nationals or natives of the United Kingdom, British Overseas Territories, and Crown Dependencies. ** Britishness, the British identity and common culture * British English, the English language as spoken and written in the United Kingdom or, more broadly, throughout the British Isles * Celtic Britons, an ancient ethno-linguistic group * Brittonic languages, a branch of the Insular Celtic language family (formerly called British) ** Common Brittonic, an ancient language Other uses *''Brit(ish)'', a 2018 memoir by Afua Hirsch *People or things associated with: ** Great Britain, an island ** United Kingdom, a sovereign state ** Kingdom of Great Britain (1707–1800) ** United Kingdom of Great Britain and Ireland (1801–1922) See also * Terminology of the British Isles * Alternative names for the British * English (other) * Britannic (other) * British Isles * Brit (other) * Briton (d ...
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International Space Station
The International Space Station (ISS) is the largest modular space station currently in low Earth orbit. It is a multinational collaborative project involving five participating space agencies: NASA (United States), Roscosmos (Russia), JAXA (Japan), ESA (Europe), and CSA (Canada). The ownership and use of the space station is established by intergovernmental treaties and agreements. The station serves as a microgravity and space environment research laboratory in which scientific research is conducted in astrobiology, astronomy, meteorology, physics, and other fields. The ISS is suited for testing the spacecraft systems and equipment required for possible future long-duration missions to the Moon and Mars. The ISS programme evolved from the Space Station ''Freedom'', a 1984 American proposal to construct a permanently crewed Earth-orbiting station, and the contemporaneous Soviet/Russian '' Mir-2'' proposal from 1976 with similar aims. The ISS is the ninth space station to ...
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SpaceX
Space Exploration Technologies Corp. (SpaceX) is an American spacecraft manufacturer, launcher, and a satellite communications corporation headquartered in Hawthorne, California. It was founded in 2002 by Elon Musk with the stated goal of reducing space transportation costs to enable the colonization of Mars. The company manufactures the Falcon 9, Falcon Heavy, and Starship launch vehicles, several rocket engines, Cargo Dragon and Crew Dragon spacecraft, and Starlink communications satellites. SpaceX is developing a satellite internet constellation named Starlink to provide commercial internet service. In January 2020, the Starlink constellation became the largest satellite constellation ever launched, and as of December 2022 comprises over 3,300 small satellites in orbit. The company is also developing Starship, a privately funded, fully reusable, super heavy-lift launch system for interplanetary and orbital spaceflight. It is intended to become SpaceX's primary orbi ...
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Yaniv Erlich
Yaniv Erlich is an Israeli-American scientist. He formerly served as an Associate Professor of Computer Science at Columbia University and was the Chief Science Officer of MyHeritage. Erlich's work combines computer science and genomics. Biography Erlich was born in Israel. He earned BSc in Brain Sciences in 2006 from Tel Aviv University and a PhD in bioinformatics in 2010 from Watson School of Biological Sciences at Cold Spring Harbor Laboratory. From 2010 to 2015, Erlich was a Fellow at the Whitehead Institute, MIT. From 2015 to 2019, he lead a lab at Columbia University in computational genomics . From 2020 to present, he has served as CEO of Eleven Therapeutics Scientific work Crowd sourcing genomic information Erlich's team published a study in the journal Science that reported crowd-sourcing of tens of millions of genealogical records from the website Geni.com. The team was able to create a single family tree of 13 million people that are all connected and spans t ...
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UC Santa Cruz
The University of California, Santa Cruz (UC Santa Cruz or UCSC) is a public land-grant research university in Santa Cruz, California. It is one of the ten campuses in the University of California system. Located on Monterey Bay, on the edge of the coastal community of Santa Cruz, the campus lies on of rolling, forested hills overlooking the Pacific Ocean. Founded in 1965, UC Santa Cruz began with the intention to showcase progressive, cross-disciplinary undergraduate education, innovative teaching methods and contemporary architecture. The residential college system consists of ten small colleges that were established as a variation of the Oxbridge collegiate university system. Among the Faculty is 1 Nobel Prize Laureate, 1 Breakthrough Prize in Life Sciences recipient, 12 members from the National Academy of Sciences, 28 members of the American Academy of Arts and Sciences, and 40 members of the American Association for the Advancement of Science. Eight UC Santa Cruz alumni ...
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David Haussler
David Haussler (born 1953) is an American bioinformatician known for his work leading the team that assembled the first human genome sequence in the race to complete the Human Genome Project and subsequently for comparative genome analysis that deepens understanding the molecular function and evolution of the genome. Haussler was elected a member of the National Academy of Engineering in 2018 for developments in computational learning theory and bioinformatics, including first assembly of the human genome, its analysis, and data sharing. He is a distinguished professor of biomolecular engineering and founding scientific director of the UC Santa Cruz Genomics Institute at the University of California, Santa Cruz, director of the California Institute for Quantitative Biosciences (QB3) on the UC Santa Cruz campus, and a consulting professor at the Stanford University School of Medicine and the UC San Francisco Biopharmaceutical Sciences Department. Education Haussler studied art ...
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Software
Software is a set of computer programs and associated documentation and data. This is in contrast to hardware, from which the system is built and which actually performs the work. At the lowest programming level, executable code consists of machine language instructions supported by an individual processor—typically a central processing unit (CPU) or a graphics processing unit (GPU). Machine language consists of groups of binary values signifying processor instructions that change the state of the computer from its preceding state. For example, an instruction may change the value stored in a particular storage location in the computer—an effect that is not directly observable to the user. An instruction may also invoke one of many input or output operations, for example displaying some text on a computer screen; causing state changes which should be visible to the user. The processor executes the instructions in the order they are provided, unless it is instructed ...
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YouTube
YouTube is a global online video platform, online video sharing and social media, social media platform headquartered in San Bruno, California. It was launched on February 14, 2005, by Steve Chen, Chad Hurley, and Jawed Karim. It is owned by Google, and is the List of most visited websites, second most visited website, after Google Search. YouTube has more than 2.5 billion monthly users who collectively watch more than one billion hours of videos each day. , videos were being uploaded at a rate of more than 500 hours of content per minute. In October 2006, YouTube was bought by Google for $1.65 billion. Google's ownership of YouTube expanded the site's business model, expanding from generating revenue from advertisements alone, to offering paid content such as movies and exclusive content produced by YouTube. It also offers YouTube Premium, a paid subscription option for watching content without ads. YouTube also approved creators to participate in Google's Google AdSens ...
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