Open Synthetic Biology
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Open Synthetic Biology
Open synthetic biology is the idea that scientific knowledge and data should be openly accessible through common rights licensing to enable the rapid development of safe, effective and commercially viable synthetic biology applications. Concepts Its foundational concepts are open science and the Bermuda Principles The Bermuda Principles set out rules for the rapid and public release of DNA sequence data. The Human Genome Project, a multinational effort to sequence the human genome, generated vast quantities of data about the genetic make-up of humans and ot .... Open science is the idea that scientific research should be openly shared to enable massive collaboration (e.g., the Polymath Project). The Bermuda Principles is a private accord declaring that all DNA sequence data should be released in publicly accessible databases within 24 hours after generation. Open synthetic biology is a theoretical framework supporting a global ecosystem of responsible and capable research sc ...
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Synthetic Biology
Synthetic biology (SynBio) is a multidisciplinary area of research that seeks to create new biological parts, devices, and systems, or to redesign systems that are already found in nature. It is a branch of science that encompasses a broad range of methodologies from various disciplines, such as biotechnology, biomaterials, material science/engineering, genetic engineering, molecular biology, molecular engineering, systems biology, membrane science, biophysics, chemical and biological engineering, electrical and computer engineering, control engineering and evolutionary biology. Due to more powerful genetic engineering capabilities and decreased DNA synthesis and sequencing costs, the field of synthetic biology is rapidly growing. In 2016, more than 350 companies across 40 countries were actively engaged in synthetic biology applications; all these companies had an estimated net worth of $3.9 billion in the global market. Definition Synthetic biology currently has no gen ...
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Bermuda Principles
The Bermuda Principles set out rules for the rapid and public release of DNA sequence data. The Human Genome Project, a multinational effort to sequence the human genome, generated vast quantities of data about the genetic make-up of humans and other organisms. But, in some respects, even more remarkable than the impressive quantity of data generated by the Human Genome Project is the speed at which that data has been released to the public. At a 1996 summit in Bermuda, leaders of the scientific community agreed on a groundbreaking set of principles requiring that all DNA sequence data be released in publicly accessible databases within twenty-four hours after generation. These "Bermuda Principles" (also known as the "Bermuda Accord") contravened the typical practice in the sciences of making experimental data available only after publication. These principles represent a significant achievement of private ordering in shaping the practices of an entire industry and have established ...
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DNA2
DNA2 may refer to: * '' DNA²'', a Japanese science fiction manga series * DNA2 (gene) DNA2-like helicase is an enzyme that in humans is encoded by the ''DNA2'' gene. Dna2, a homolog of DNA2KL present in budding yeast, possesses both helicase and nuclease activity, with which it helps catalyze early steps in homologous recombinatio ...
, a human gene which encodes the enzyme DNA2-like helicase {{disambiguation ...
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BioBricks Foundation
BioBrick parts are DNA sequences which conform to a restriction-enzyme assembly standard. These building blocks are used to design and assemble larger synthetic biological circuits from individual parts and combinations of parts with defined functions, which would then be incorporated into living cells such as ''Escherichia coli'' cells to construct new biological systems. Examples of BioBrick parts include promoters, ribosomal binding sites (RBS), coding sequences and terminators. Overview The BioBrick parts are used by applying engineering principles of abstraction and modularization. BioBrick parts form the base of the hierarchical system on which synthetic biology is based. There are three levels to the hierarchy: # Parts: Pieces of DNA that form a functional unit (for example promoter, RBS, etc.) # Device: Collection set of parts with defined function. In simple terms, a set of complementary BioBrick parts put together forms a device. # System: Combination of a set of dev ...
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Synthetic Biology
Synthetic biology (SynBio) is a multidisciplinary area of research that seeks to create new biological parts, devices, and systems, or to redesign systems that are already found in nature. It is a branch of science that encompasses a broad range of methodologies from various disciplines, such as biotechnology, biomaterials, material science/engineering, genetic engineering, molecular biology, molecular engineering, systems biology, membrane science, biophysics, chemical and biological engineering, electrical and computer engineering, control engineering and evolutionary biology. Due to more powerful genetic engineering capabilities and decreased DNA synthesis and sequencing costs, the field of synthetic biology is rapidly growing. In 2016, more than 350 companies across 40 countries were actively engaged in synthetic biology applications; all these companies had an estimated net worth of $3.9 billion in the global market. Definition Synthetic biology currently has no gen ...
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