DNA2 may refer to:
* ''
DNA²'', a Japanese science fiction manga series
*
DNA2 (gene)
DNA2-like helicase is an enzyme that in humans is encoded by the ''DNA2'' gene. Dna2, a homolog of DNA2KL present in budding yeast, possesses both helicase and nuclease activity, with which it helps catalyze early steps in homologous recombinatio ...
, a human gene which encodes the enzyme DNA2-like helicase
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