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Open Problem
In science and mathematics, an open problem or an open question is a known problem which can be accurately stated, and which is assumed to have an objective and verifiable solution, but which has not yet been solved (i.e., no solution for it is known). In the history of science, some of these supposed open problems were "solved" by means of showing that they were not well-defined. In mathematics, many open problems are concerned with the question of whether a certain definition is or is not consistent. Two notable examples in mathematics that have been solved and ''closed'' by researchers in the late twentieth century are Fermat's Last Theorem and the four-color theorem.K. Appel and W. Haken (1977), "Every planar map is four colorable. Part I. Discharging", ''Illinois J. Math'' 21: 429–490. K. Appel, W. Haken, and J. Koch (1977), "Every planar map is four colorable. Part II. Reducibility", ''Illinois J. Math'' 21: 491–567. An important open mathematics problem solve ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Science
Science is a systematic endeavor that Scientific method, builds and organizes knowledge in the form of Testability, testable explanations and predictions about the universe. Science may be as old as the human species, and some of the earliest archeological evidence for scientific reasoning is tens of thousands of years old. The earliest written records in the history of science come from Ancient Egypt and Mesopotamia in around 3000 to 1200 Common Era, BCE. Their contributions to mathematics, astronomy, and medicine entered and shaped Greek natural philosophy of classical antiquity, whereby formal attempts were made to provide explanations of events in the Universe, physical world based on natural causes. After the fall of the Western Roman Empire, knowledge of History of science in classical antiquity, Greek conceptions of the world deteriorated in Western Europe during the early centuries (400 to 1000 CE) of the Middle Ages, but was preserved in the Muslim world during the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mathematics
Mathematics is an area of knowledge that includes the topics of numbers, formulas and related structures, shapes and the spaces in which they are contained, and quantities and their changes. These topics are represented in modern mathematics with the major subdisciplines of number theory, algebra, geometry, and analysis, respectively. There is no general consensus among mathematicians about a common definition for their academic discipline. Most mathematical activity involves the discovery of properties of abstract objects and the use of pure reason to prove them. These objects consist of either abstractions from nature orin modern mathematicsentities that are stipulated to have certain properties, called axioms. A ''proof'' consists of a succession of applications of deductive rules to already established results. These results include previously proved theorems, axioms, andin case of abstraction from naturesome basic properties that are considered true starting poin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
History Of Science
The history of science covers the development of science from ancient times to the present. It encompasses all three major branches of science: natural, social, and formal. Science's earliest roots can be traced to Ancient Egypt and Mesopotamia around 3000 to 1200 BCE. These civilizations' contributions to mathematics, astronomy, and medicine influenced later Greek natural philosophy of classical antiquity, wherein formal attempts were made to provide explanations of events in the physical world based on natural causes. After the fall of the Western Roman Empire, knowledge of Greek conceptions of the world deteriorated in Latin-speaking Western Europe during the early centuries (400 to 1000 CE) of the Middle Ages, but continued to thrive in the Greek-speaking Eastern Roman (or Byzantine) Empire. Aided by translations of Greek texts, the Hellenistic worldview was preserved and absorbed into the Arabic-speaking Muslim world during the Islamic Golden Age. The recovery an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fermat's Last Theorem
In number theory, Fermat's Last Theorem (sometimes called Fermat's conjecture, especially in older texts) states that no three positive integers , , and satisfy the equation for any integer value of greater than 2. The cases and have been known since antiquity to have infinitely many solutions.Singh, pp. 18–20. The proposition was first stated as a theorem by Pierre de Fermat around 1637 in the margin of a copy of ''Arithmetica''. Fermat added that he had a proof that was too large to fit in the margin. Although other statements claimed by Fermat without proof were subsequently proven by others and credited as theorems of Fermat (for example, Fermat's theorem on sums of two squares), Fermat's Last Theorem resisted proof, leading to doubt that Fermat ever had a correct proof. Consequently the proposition became known as a conjecture rather than a theorem. After 358 years of effort by mathematicians, the first successful proof was released in 1994 by Andrew Wiles and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Four-color Theorem
In mathematics, the four color theorem, or the four color map theorem, states that no more than four colors are required to color the regions of any map so that no two adjacent regions have the same color. ''Adjacent'' means that two regions share a common boundary curve segment, not merely a corner where three or more regions meet. It was the first major theorem to be proved using a computer. Initially, this proof was not accepted by all mathematicians because the computer-assisted proof was infeasible for a human to check by hand. The proof has gained wide acceptance since then, although some doubters remain. The four color theorem was proved in 1976 by Kenneth Appel and Wolfgang Haken after many false proofs and counterexamples (unlike the five color theorem, proved in the 1800s, which states that five colors are enough to color a map). To dispel any remaining doubts about the Appel–Haken proof, a simpler proof using the same ideas and still relying on computers was p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Poincaré Conjecture
In the mathematical field of geometric topology, the Poincaré conjecture (, , ) is a theorem about the characterization of the 3-sphere, which is the hypersphere that bounds the unit ball in four-dimensional space. Originally conjectured by Henri Poincaré in 1904, the Grigori Perelman's theorem concerns spaces that locally look like ordinary three-dimensional space but which are finite in extent. Poincaré hypothesized that if such a space has the additional property that each loop in the space can be continuously tightened to a point, then it is necessarily a three-dimensional sphere. Attempts to resolve the conjecture drove much progress in the field of geometric topology during the 20th century. The Perelman's proof built upon Richard S. Hamilton's ideas of using the Ricci flow to solve the problem. By developing a number of breakthrough new techniques and results in the theory of Ricci flow, Grigori Perelman was able to prove the Conjecture, and more than just the C ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Protein Structure Prediction
Protein structure prediction is the inference of the three-dimensional structure of a protein from its amino acid sequence—that is, the prediction of its secondary and tertiary structure from primary structure. Structure prediction is different from the inverse problem of protein design. Protein structure prediction is one of the most important goals pursued by computational biology; and it is important in medicine (for example, in drug design) and biotechnology (for example, in the design of novel enzymes). Starting in 1994, the performance of current methods is assessed biannually in the CASP experiment (Critical Assessment of Techniques for Protein Structure Prediction). A continuous evaluation of protein structure prediction web servers is performed by the community project CAMEO3D. Protein structure and terminology Proteins are chains of amino acids joined together by peptide bonds. Many conformations of this chain are possible due to the rotation of the main chain ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, responding to stimuli, providing structure to cells and organisms, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific 3D structure that determines its activity. A linear chain of amino acid residues is called a polypeptide. A protein contains at least one long polypeptide. Short polypeptides, containing less than 20–30 residues, are rarely considered to be proteins and are commonly called peptides. The individual amino acid residues are bonded together by peptide bonds and adjacent amino acid residues. The sequence of amino acid resid ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lists Of Unsolved Problems
List of unsolved problems may refer to several notable conjectures or open problems in various academic fields: Natural sciences, engineering and medicine * Unsolved problems in astronomy * Unsolved problems in biology * Unsolved problems in chemistry * Unsolved problems in engineering * Unsolved problems in geoscience * Unsolved problems in medicine * Unsolved problems in neuroscience * Unsolved problems in physics Mathematics, philosophy and information sciences * Unsolved problems in mathematics * Unsolved problems in statistics * Unsolved problems in computer science * Unsolved problems in philosophy * Unsolved problems in information theory Social sciences and languages * Unsolved problems in economics * Unsolved problems in fair division * Unsolved problems in linguistics See also * Cold case (unsolved crimes) * List of ciphertexts * List of NP-complete problems This is a list of some of the more commonly known problems that are NP-complete when expressed ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hilbert's Problems
Hilbert's problems are 23 problems in mathematics published by German mathematician David Hilbert in 1900. They were all unsolved at the time, and several proved to be very influential for 20th-century mathematics. Hilbert presented ten of the problems (1, 2, 6, 7, 8, 13, 16, 19, 21, and 22) at the Paris conference of the International Congress of Mathematicians, speaking on August 8 at the Sorbonne. The complete list of 23 problems was published later, in English translation in 1902 by Mary Frances Winston Newson in the ''Bulletin of the American Mathematical Society''. Earlier publications (in the original German) appeared in and Nature and influence of the problems Hilbert's problems ranged greatly in topic and precision. Some of them, like the 3rd problem, which was the first to be solved, or the 8th problem (the Riemann hypothesis), which still remains unresolved, were presented precisely enough to enable a clear affirmative or negative answer. For other proble ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Millennium Prize Problems
The Millennium Prize Problems are seven well-known complex mathematical problems selected by the Clay Mathematics Institute in 2000. The Clay Institute has pledged a US$1 million prize for the first correct solution to each problem. According to the official website of the Clay Mathematics Institute, the Millennium Prize Problems are officially also called the Millennium Problems. To date, the only Millennium Prize problem to have been solved is the Poincaré conjecture. The Clay Institute awarded the monetary prize to Russian mathematician Grigori Perelman in 2010. However, he declined the award as it was not also offered to Richard S. Hamilton, upon whose work Perelman built. The remaining six unsolved problems are the Birch and Swinnerton-Dyer conjecture, Hodge conjecture, Navier–Stokes existence and smoothness, P versus NP problem, Riemann hypothesis, and Yang–Mills existence and mass gap. Overview The Clay Institute was inspired by a set of twenty-three problems ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
