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Oxygen Cascade
In respiratory physiology, the oxygen cascade describes the flow of oxygen from air to mitochondria. Oxygen flows from areas with high partial pressure of oxygen (PO2, also known as oxygen tension) to areas of lower PO2. Air is typically around 21% oxygen, and at sea level, the PO2 of air is typically around 159 mmHg. Humidity dilutes the concentration of oxygen in air. As air is breathed into the lungs, it mixes with water and exhaust gasses including CO2, further diluting the oxygen concentration and lowering the PO2. As oxygen continues to flow from areas of higher concentration to lower concentration, it passes many barriers such as the alveoli, capillary walls, capillary plasma, red blood cell walls, interstitial space, other cell walls, and cell cytoplasm. The partial pressure of oxygen drops across each barrier. Table 1 gives the example of a typical oxygen cascade for a skeletal muscle of healthy, adult male at rest who is breathing air at atmospheric pressure. Actual valu ...
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Respiratory Physiology
In physiology, respiration is the movement of oxygen from the outside environment to the cells within Tissue (biology), tissues, and the transport, removal of carbon dioxide in the opposite direction that's to the environment. The physiological definition of respiration differs from the Cellular respiration, biochemical definition, which refers to a metabolic process by which an organism obtains energy (in the form of ATP and NADPH) by oxidizing nutrients and releasing waste products. Although physiologic respiration is necessary to sustain cellular respiration and thus life in animals, the processes are distinct: cellular respiration takes place in individual cells of the organism, while physiologic respiration concerns the Diffusion#Diffusion vs. bulk flow diffusion, diffusion and transport of metabolites between the organism and the external environment. Gas exchanges in the lung occurs by ventilation and perfusion. Ventilation refers to the in and out movement of air of the lu ...
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Intracellular Space
Intracellular space is the interior space of the plasma membrane. It contains about two-thirds of TBW. Cellular rupture may occur if the intracellular space becomes dehydrated, or if the opposite happens, where it becomes too bloated. Thus it is important for the liquid to stay in optimal quantity. See also *Extracellular space Extracellular space refers to the part of a multicellular organism outside the cells, usually taken to be outside the plasma membranes, and occupied by fluid. This is distinguished from intracellular space, which is inside the cells. The compos ... References {{Cellular structures Cell anatomy Cell biology ...
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Cellular Respiration
Cellular respiration is the process by which biological fuels are oxidised in the presence of an inorganic electron acceptor such as oxygen to produce large amounts of energy, to drive the bulk production of ATP. Cellular respiration may be described as a set of metabolic reactions and processes that take place in the cells of organisms to convert chemical energy from nutrients into adenosine triphosphate (ATP), and then release waste products. The reactions involved in respiration are catabolic reactions, which break large molecules into smaller ones, releasing energy. Respiration is one of the key ways a cell releases chemical energy to fuel cellular activity. The overall reaction occurs in a series of biochemical steps, some of which are redox reactions. Although cellular respiration is technically a combustion reaction, it is an unusual one because of the slow, controlled release of energy from the series of reactions. Nutrients that are commonly used by animal and plan ...
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Respiratory Physiology
In physiology, respiration is the movement of oxygen from the outside environment to the cells within Tissue (biology), tissues, and the transport, removal of carbon dioxide in the opposite direction that's to the environment. The physiological definition of respiration differs from the Cellular respiration, biochemical definition, which refers to a metabolic process by which an organism obtains energy (in the form of ATP and NADPH) by oxidizing nutrients and releasing waste products. Although physiologic respiration is necessary to sustain cellular respiration and thus life in animals, the processes are distinct: cellular respiration takes place in individual cells of the organism, while physiologic respiration concerns the Diffusion#Diffusion vs. bulk flow diffusion, diffusion and transport of metabolites between the organism and the external environment. Gas exchanges in the lung occurs by ventilation and perfusion. Ventilation refers to the in and out movement of air of the lu ...
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