Olga Ornatsky
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Olga Ornatsky
Olga Ornatsky is a Soviet born, Canadian scientist. Ornatsky co-founded DVS Sciences in 2004 (acquired by Fluidigm in 2014 and then renamed to Standard BioTools in 2022) along with Dmitry Bandura, Vladimir Baranov and Scott D. Tanner. Biography Ornatsky graduated from the Moscow State University, Department of Biology. In 1989, she completed her Ph.D. in Cell & Molecular Biology, and worked as a Research Scientist at the Cardiology Centre studying vascular smooth muscle involvement in atherosclerosis. In 1993, she immigrated to Canada, and became a Postdoctoral Research Fellow at York University. She quickly progressed to become Senior Research Associate in the Laboratory of Vascular Biology and Cardiac Surgery at St. Michael's Hospital (Toronto). Her achievements brought her to MDS Proteomics Inc. (noProtana Inc, where she led her research group as a Senior Scientist for four years. In 2005, she left MDS to pursue a different direction. Together with the co-founders of DVS S ...
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Mass Cytometry
Mass cytometry is a mass spectrometry technique based on inductively coupled plasma mass spectrometry and time of flight mass spectrometry used for the determination of the properties of cells (cytometry). In this approach, antibodies are conjugated with isotopically pure elements, and these antibodies are used to label cellular proteins. Cells are nebulized and sent through an argon plasma, which ionizes the metal-conjugated antibodies. The metal signals are then analyzed by a time-of-flight mass spectrometer. The approach overcomes limitations of spectral overlap in flow cytometry by utilizing discrete isotopes as a reporter system instead of traditional fluorophores which have broad emission spectra. Commercialization Tagging technology and instrument development occurred at the University of Toronto and DVS Sciences, Inc. CyTOF (cytometry by time of flight) was initially commercialized by DVS Sciences in 2009. In 2014, Fluidigm acquired DVS Sciences to become a reference ...
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Moscow State University Alumni
Moscow ( , US chiefly ; rus, links=no, Москва, r=Moskva, p=mɐskˈva, a=Москва.ogg) is the capital and largest city of Russia. The city stands on the Moskva River in Central Russia, with a population estimated at 13.0 million residents within the city limits, over 17 million residents in the urban area, and over 21.5 million residents in the metropolitan area. The city covers an area of , while the urban area covers , and the metropolitan area covers over . Moscow is among the world's largest cities; being the most populous city entirely in Europe, the largest urban and metropolitan area in Europe, and the largest city by land area on the European continent. First documented in 1147, Moscow grew to become a prosperous and powerful city that served as the capital of the Grand Duchy that bears its name. When the Grand Duchy of Moscow evolved into the Tsardom of Russia, Moscow remained the political and economic center for most of the Tsardom's history. When th ...
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Canadian Women Scientists
Canadians (french: Canadiens) are people identified with the country of Canada. This connection may be residential, legal, historical or cultural. For most Canadians, many (or all) of these connections exist and are collectively the source of their being ''Canadian''. Canada is a multilingual and multicultural society home to people of groups of many different ethnic, religious, and national origins, with the majority of the population made up of Old World immigrants and their descendants. Following the initial period of French and then the much larger British colonization, different waves (or peaks) of immigration and settlement of non-indigenous peoples took place over the course of nearly two centuries and continue today. Elements of Indigenous, French, British, and more recent immigrant customs, languages, and religions have combined to form the culture of Canada, and thus a Canadian identity. Canada has also been strongly influenced by its linguistic, geographic, and ec ...
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Canadian Biologists
Canadians (french: Canadiens) are people identified with the country of Canada. This connection may be residential, legal, historical or cultural. For most Canadians, many (or all) of these connections exist and are collectively the source of their being ''Canadian''. Canada is a multilingual and multicultural society home to people of groups of many different ethnic, religious, and national origins, with the majority of the population made up of Old World immigrants and their descendants. Following the initial period of French and then the much larger British colonization, different waves (or peaks) of immigration and settlement of non-indigenous peoples took place over the course of nearly two centuries and continue today. Elements of Indigenous, French, British, and more recent immigrant customs, languages, and religions have combined to form the culture of Canada, and thus a Canadian identity. Canada has also been strongly influenced by its linguistic, geographic, and ec ...
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Mass Spectrometrists
Mass is an intrinsic property of a body. It was traditionally believed to be related to the quantity of matter in a physical body, until the discovery of the atom and particle physics. It was found that different atoms and different elementary particles, theoretically with the same amount of matter, have nonetheless different masses. Mass in modern physics has multiple definitions which are conceptually distinct, but physically equivalent. Mass can be experimentally defined as a measure of the body's inertia, meaning the resistance to acceleration (change of velocity) when a net force is applied. The object's mass also determines the strength of its gravitational attraction to other bodies. The SI base unit of mass is the kilogram (kg). In physics, mass is not the same as weight, even though mass is often determined by measuring the object's weight using a spring scale, rather than balance scale comparing it directly with known masses. An object on the Moon would weigh l ...
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Human Proteome Organization
The Human Proteome Organization (HUPO) is an international consortium of national proteomics research associations, government researchers, academic institutions, and industry partners. The organization was launched in February 2001, and it promotes the development and awareness of proteomics research, advocates on behalf of proteomics researchers throughout the world, and facilitates scientific collaborations between members and initiatives. Ultimately, it is organized to gain a better and more complete understanding of the human proteome. Congress Since 2002, HUPO organizes one international congress each year, with past congresses held in Orlando in 2018, in Dublin in 2017, in Taiwan in 2016 and in Vancouver 2015. Awards HUPO awards multiple awards each year, among them the * Distinguished Service Award * Translational Proteomics Award * Science & Technology Award * Discovery in Proteomic Sciences Award * Distinguished Achievement Award in Proteomic Sciences See also * Human ...
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Mass Cytometry
Mass cytometry is a mass spectrometry technique based on inductively coupled plasma mass spectrometry and time of flight mass spectrometry used for the determination of the properties of cells (cytometry). In this approach, antibodies are conjugated with isotopically pure elements, and these antibodies are used to label cellular proteins. Cells are nebulized and sent through an argon plasma, which ionizes the metal-conjugated antibodies. The metal signals are then analyzed by a time-of-flight mass spectrometer. The approach overcomes limitations of spectral overlap in flow cytometry by utilizing discrete isotopes as a reporter system instead of traditional fluorophores which have broad emission spectra. Commercialization Tagging technology and instrument development occurred at the University of Toronto and DVS Sciences, Inc. CyTOF (cytometry by time of flight) was initially commercialized by DVS Sciences in 2009. In 2014, Fluidigm acquired DVS Sciences to become a reference ...
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University Of Toronto
The University of Toronto (UToronto or U of T) is a public research university in Toronto, Ontario, Canada, located on the grounds that surround Queen's Park. It was founded by royal charter in 1827 as King's College, the first institution of higher learning in Upper Canada. Originally controlled by the Church of England, the university assumed its present name in 1850 upon becoming a secular institution. As a collegiate university, it comprises eleven colleges each with substantial autonomy on financial and institutional affairs and significant differences in character and history. The university maintains three campuses, the oldest of which, St. George, is located in downtown Toronto. The other two satellite campuses are located in Scarborough and Mississauga. The University of Toronto offers over 700 undergraduate and 200 graduate programs. In all major rankings, the university consistently ranks in the top ten public universities in the world and as the top university ...
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CyTOF
Cytometry by time of flight, or CyTOF, is an application of mass cytometry used to quantify labeled targets on the surface and interior of single cells. CyTOF allows the quantification of multiple cellular components simultaneously using an ICP-MS detector. CyTOF takes advantage of immunolabeling to quantify proteins, carbohydrates or lipids in a cell. Targets are selected to answer a specific research question and are labeled with lanthanide metal tagged antibodies. Labeled cells are nebulized and mixed with heated argon gas to dry the cell containing particles. The sample-gas mixture is focused and ignited with an argon plasma torch.  This breaks the cells into their individual atoms and creates an ion cloud. Abundant low weight ions generated from environmental air and biological molecules are removed using a quadrupole mass analyzer. The remaining heavy ions from the antibody tags are quantified by Time-of-flight mass spectrometry. Ion abundances correlate with the amount of ...
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Canadian
Canadians (french: Canadiens) are people identified with the country of Canada. This connection may be residential, legal, historical or cultural. For most Canadians, many (or all) of these connections exist and are collectively the source of their being ''Canadian''. Canada is a multilingual and multicultural society home to people of groups of many different ethnic, religious, and national origins, with the majority of the population made up of Old World immigrants and their descendants. Following the initial period of French and then the much larger British colonization, different waves (or peaks) of immigration and settlement of non-indigenous peoples took place over the course of nearly two centuries and continue today. Elements of Indigenous, French, British, and more recent immigrant customs, languages, and religions have combined to form the culture of Canada, and thus a Canadian identity. Canada has also been strongly influenced by its linguistic, geographic, and ec ...
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York University
York University (french: Université York), also known as YorkU or simply YU, is a public university, public research university in Toronto, Ontario, Canada. It is Canada's fourth-largest university, and it has approximately 55,700 students, 7,000 faculty and staff, and over 325,000 alumni worldwide. It has 11 faculties, including the Faculty of Liberal Arts and Professional Studies, Faculty of Science, Lassonde School of Engineering, Schulich School of Business, Osgoode Hall Law School, Glendon College, Faculty of Education, Faculty of Health, Faculty of Environmental and Urban Change, Faculty of Graduate Studies, School of the Arts, Media, Performance and Design, and 28 research centres. York University was established in 1959 as a non-denominational institution by the ''York University Act'', which received royal assent in the Legislative Assembly of Ontario on 26 March of that year. Its first class was held in September 1960 in Falconer Hall on the University of Toronto campu ...
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