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Okazaki Fragment EN
Okazaki may refer to: *Okazaki (surname) *Okazaki, Aichi, a city in Japan *Okazaki Castle, a castle in Japan *Okazaki fragments Okazaki fragments are short sequences of DNA nucleotides (approximately 150 to 200 base pairs long in eukaryotes) which are synthesized discontinuously and later linked together by the enzyme DNA ligase to create the lagging strand during DNA ..., DNA fragments formed during DNA replication (biology) See also * Okasaki {{disambiguation ...
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Okazaki (surname)
Okazaki (written: ) is a Japanese surname. Notable people with the surname include: *Chieko N. Okazaki (1926–2011), former counselor in the General Relief Society Presidency of the Church of Jesus Christ of Latter-day Saints *Smelly (performer), Dai Okazaki (AKA "Smelly", born 1971), Japanese comedic performer and former manga artist *, Japanese alpine skier *, Japanese shogi player *Isao Okazaki (1920–2006), Japanese right-wing activist *Katsuo Okazaki (1897–1965), served as the Minister for Foreign Affairs (Japan), Japanese Foreign Minister between 1952 and 1954 *Kenjiro Okazaki (born 1955), Japanese visual artist *Kyoko Okazaki (born 1963), a Japanese manga artist, winner of the Tezuka Osamu Cultural Prize in 2004 *Makoto Okazaki (other), multiple people *Miles Okazaki (born 1974), American guitarist, arranger, and composer *Reiji Okazaki (1930–1975), Japanese scientist *Ritsuko Okazaki (1959–2004), Japanese singer-songwriter *, Japanese gymnast *Seishiro Ok ...
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Okazaki, Aichi
is a city located in Aichi Prefecture, Japan. , the city had an estimated population of 386,999 in 164,087 households, and a population density of 999 persons per km². The total area of the city was . Geography Okazaki is in the coastal plains of southeastern Aichi Prefecture. The ground rises to undulating hills in the former Nukata area to the northeast. About 60 percent of the city area is forested and remains sparsely populated. Okazaki is about from Tokyo, to the southwest. Climate The city has a climate characterized by hot and humid summers, and relatively mild winters (Köppen climate classification ''Cfa''). The average annual temperature in Okazaki is . The average annual rainfall is with September as the wettest month. The temperatures are highest on average in August, at around , and lowest in January, at around . Demographics Per Japanese census data, the population of Okazaki has grown steadily over the past 60 years. This fast population growth reflects the l ...
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Okazaki Castle
is a Japanese castle located in Okazaki, Aichi Prefecture, Japan. At the end of the Edo period, Okazaki Castle was home to the Honda clan, ''daimyō'' of Okazaki Domain, but the castle is better known for its association with Tokugawa Ieyasu and the Tokugawa clan. The castle was also known as . History Saigo Tsugiyori built an earthen-walled fortification in the Myodaiji area of Okazaki, near the present castle in 1455. Matsudaira Kiyoyasu, after gaining control of the area in 1524, demolished the old fortification and built Okazaki Castle on its present location. His famous grandson Matsudaira Motoyasu (later named Tokugawa Ieyasu) was born here on December 16, 1542. The Matsudaira were defeated by the Imagawa clan in 1549, and Ieyasu was taken to Sunpu Castle as a hostage. Following the defeat of the Imagawa at the Battle of Okehazama, Ieyasu regained possession of the castle in 1560 and left his eldest son Matsudaira Nobuyasu in charge when he moved to Hamamatsu Castle in 1 ...
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Okazaki Fragments
Okazaki fragments are short sequences of DNA nucleotides (approximately 150 to 200 base pairs long in eukaryotes) which are synthesized discontinuously and later linked together by the enzyme DNA ligase to create the lagging strand during DNA replication. They were discovered in the 1960s by the Japanese molecular biologists Reiji and Tsuneko Okazaki, along with the help of some of their colleagues. During DNA replication, the double helix is unwound and the complementary strands are separated by the enzyme DNA helicase, creating what is known as the DNA replication fork. Following this fork, DNA primase and DNA polymerase begin to act in order to create a new complementary strand. Because these enzymes can only work in the 5’ to 3’ direction, the two unwound template strands are replicated in different ways. One strand, the leading strand, undergoes a continuous replication process since its template strand has 3’ to 5’ directionality, allowing the polymerase assemblin ...
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