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Office Politics (House)
"Office Politics" is the sixth episode of the seventh season of the American medical drama ''House''. It aired on November 8, 2010. It is also the first episode to feature Amber Tamblyn as Martha Masters, as a replacement of Thirteen (Olivia Wilde). Plot A New Jersey senator Hal Andersons campaign manager Joe Dugan (played by Jack Coleman) falls ill with liver failure and temporary paralysis. Meanwhile, Cuddy pressures House to add a female doctor to his team but eventually tells him that she has chosen for him: a third-year med student named Martha Masters, who is a genius. Taub appears to have a problem with Masters, which Foreman and Chase try to figure out. Throughout the episode, House keeps firing and rehiring Masters, rehiring her whenever he needs her for an idea, and firing her again as soon as he's done talking to her. Masters suggests a neuroendocrine tumor, and the team also considers DIC. The team give Joe an MRI to look for a tumor, but don't find one. Taub run ...
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House (TV Series)
''House'' (also called ''House, M.D.'') is an American medical drama television series that originally ran on the Fox network for eight seasons, from November 16, 2004, to May 21, 2012. The series' main character is Dr. Gregory House (Hugh Laurie), an unconventional, misanthropic medical genius who, despite his dependence on pain medication, leads a team of diagnosticians at the fictional Princeton–Plainsboro Teaching Hospital (PPTH) in New Jersey. The series' premise originated with Paul Attanasio, while David Shore, who is credited as creator, was primarily responsible for the conception of the title character. The series' executive producers included Shore, Attanasio, Attanasio's business partner Katie Jacobs, and film director Bryan Singer. It was filmed largely in a neighborhood and business district in Los Angeles County's Westside called Century City. The show received high critical acclaim, and was consistently one of the highest rated series in the United States. ...
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Thirteen (House)
Remy "Thirteen" Hadley, M.D., is a fictional character on the Fox medical drama ''House'', portrayed by Olivia Wilde. She is part of the new diagnostic team assembled by Dr. Gregory House after the disbanding of his previous team in the third-season finale. The character's nickname derives from the episode " The Right Stuff", when she is assigned the number during a competition for her position at the Princeton-Plainsboro Teaching Hospital. The show depicts Thirteen as a secretive character who does not divulge personal information; her surname was not used on the show until the fourth season's penultimate episode "House's Head", nor her given name until the fifth-season episode "Emancipation". Instead, several of the character's traits are implied before they are depicted as true. In the season four episode "You Don't Want to Know", Thirteen tells House that her mother died from Huntington's disease; a test she performs several episodes later confirms she carries the gene. Aft ...
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The A
''The'' () is a grammatical article in English, denoting persons or things already mentioned, under discussion, implied or otherwise presumed familiar to listeners, readers, or speakers. It is the definite article in English. ''The'' is the most frequently used word in the English language; studies and analyses of texts have found it to account for seven percent of all printed English-language words. It is derived from gendered articles in Old English which combined in Middle English and now has a single form used with pronouns of any gender. The word can be used with both singular and plural nouns, and with a noun that starts with any letter. This is different from many other languages, which have different forms of the definite article for different genders or numbers. Pronunciation In most dialects, "the" is pronounced as (with the voiced dental fricative followed by a schwa) when followed by a consonant sound, and as (homophone of pronoun ''thee'') when followed by a ...
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Euler's Number
The number , also known as Euler's number, is a mathematical constant approximately equal to 2.71828 that can be characterized in many ways. It is the base of a logarithm, base of the natural logarithms. It is the Limit of a sequence, limit of as approaches infinity, an expression that arises in the study of compound interest. It can also be calculated as the sum of the infinite Series (mathematics), series e = \sum\limits_^ \frac = 1 + \frac + \frac + \frac + \cdots. It is also the unique positive number such that the graph of the function has a slope of 1 at . The (natural) exponential function is the unique function that equals its own derivative and satisfies the equation ; hence one can also define as . The natural logarithm, or logarithm to base , is the inverse function to the natural exponential function. The natural logarithm of a number can be defined directly as the integral, area under the curve between and , in which case is the value of for which ...
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Johns Hopkins Medical School
The Johns Hopkins University School of Medicine (JHUSOM) is the medical school of Johns Hopkins University, a private research university in Baltimore, Maryland. Founded in 1893, the School of Medicine shares a campus with the Johns Hopkins Hospital and Johns Hopkins Children's Center, established in 1889. It has consistently ranked among the top medical schools in the United States in terms of the number/amount of research grants/funding awarded by the National Institutes of Health, among other measures. History The founding physicians (the "Four Doctors") of the Johns Hopkins School of Medicine included pathologist William Henry Welch (1850–1934), the first dean of the school and a mentor to generations of research scientists; a Canadian, internist Sir William Osler (1849–1919), regarded as the ''Father of Modern Medicine'', having been perhaps the most influential physician of the late 19th and early 20th centuries as author of '' The Principles and Practice of Medicine'' ...
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Interferon
Interferons (IFNs, ) are a group of signaling proteins made and released by host cells in response to the presence of several viruses. In a typical scenario, a virus-infected cell will release interferons causing nearby cells to heighten their anti-viral defenses. IFNs belong to the large class of proteins known as cytokines, molecules used for communication between cells to trigger the protective defenses of the immune system that help eradicate pathogens. Interferons are named for their ability to "interfere" with viral replication by protecting cells from virus infections. However, virus-encoded genetic elements have the ability to antagonize the IFN response contributing to viral pathogenesis and viral diseases. IFNs also have various other functions: they activate immune cells, such as natural killer cells and macrophages, and they increase host defenses by up-regulating antigen presentation by virtue of increasing the expression of major histocompatibility complex (M ...
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Disseminated Intravascular Coagulation
Disseminated intravascular coagulation (DIC) is a condition in which blood clots form throughout the body, blocking small blood vessels. Symptoms may include chest pain, shortness of breath, leg pain, problems speaking, or problems moving parts of the body. As clotting factors and platelets are used up, bleeding may occur. This may include blood in the urine, blood in the stool, or bleeding into the skin. Complications may include organ failure. Relatively common causes include sepsis, surgery, major trauma, cancer, and complications of pregnancy. Less common causes include snake bites, frostbite, and burns. There are two main types: acute (rapid onset) and chronic (slow onset). Diagnosis is typically based on blood tests. Findings may include low platelets, low fibrinogen, high INR, or high D-dimer. Treatment is mainly directed towards the underlying condition. Other measures may include giving platelets, cryoprecipitate, or fresh frozen plasma. Evidence to support these trea ...
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Neuroendocrine Tumor
Neuroendocrine tumors (NETs) are neoplasms that arise from cells of the endocrine (hormonal) and nervous systems. They most commonly occur in the intestine, where they are often called carcinoid tumors, but they are also found in the pancreas, lung, and the rest of the body. Although there are many kinds of NETs, they are treated as a group of tissue because the cells of these neoplasms share common features, such as looking similar, having special secretory granules, and often producing biogenic amines and polypeptide hormones. Classification WHO The World Health Organization (WHO) classification scheme places neuroendocrine tumors into three main categories, which emphasize the tumor grade rather than the anatomical origin: * well-differentiated neuroendocrine tumours, further subdivided into tumors with benign and those with uncertain behavior * well-differentiated (low grade) neuroendocrine carcinomas with low-grade malignant behavior * poorly differentiated (high grade) ...
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Olivia Wilde
Olivia Jane Cockburn ( ; born March 10, 1984), known professionally as Olivia Wilde, is an American actress and filmmaker. She played Thirteen (House), Remy "Thirteen" Hadley on the medical-drama television series ''House (TV series), House'' (2007–2012), and has appeared in the films ''Tron: Legacy'' (2010), ''Cowboys & Aliens'' (2011), ''The Incredible Burt Wonderstone'' (2013), and ''The Lazarus Effect (2015 film), The Lazarus Effect'' (2015). Wilde made her Broadway theatre, Broadway debut in 2017, playing Julia (Nineteen Eighty-Four), Julia in ''1984 (play), 1984''. In 2019, she directed her first film, the teen comedy ''Booksmart'', for which she won the Independent Spirit Award for Best First Feature. Wilde's second feature as director, ''Don't Worry Darling'', was released in 2022. Early life Wilde was born Olivia Jane Cockburn in New York City on March 10, 1984. She grew up in the Georgetown (Washington, D.C.), Georgetown neighborhood of Washington, D.C. while spendi ...
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Martha Masters (House)
Martha M. Masters is a fictional character on the Fox medical drama television series ''House''. Masters is portrayed by American actress Amber Tamblyn. She appears in a multi-episode arc of season 7, and very briefly in the series finale, " Everybody Dies". Biography After graduating from high school at age 15, Masters obtained doctorate degrees in both applied math and art history. In the episode "Office Politics", Dr. Lisa Cuddy hires Masters, a medical student, for the position on Dr. House's diagnostic team left vacant by Thirteen. House once described Masters as having "nervous, anxious energy" when describing the list of candidates Taub had to pick from to study with when being re-certified by the American Board of Internal Medicine (ABIM). In the episode "Family Practice", House threatens to have Masters thrown out of medical school if she tells Cuddy or her mother's physician about switching her medication. Despite this, she informs both groups and still retains her j ...
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Sanford Bookstaver
Sanford Bookstaver (born September 1, 1973) is an American film, television director and television producer. Early life In 1995, Bookstaver graduated from the USC School of Cinema-Television The University of Southern California School of Cinematic Arts (SCA) houses seven academic divisions: Film & Television Production; Cinema & Media Studies; John C. Hench Division of Animation + Digital Arts; John Wells Division of Writing for Sc .... In 1999, he directed the film ''Scriptfellas''. Television As a television director, some of Bookstaver's episodic credits include ''Prison Break'', ''The O.C.'', Chicago Fire (TV series), Chicago Fire, Chicago P.D. (TV series), Chicago PD, ''Dawson's Creek'', ''One Tree Hill (TV series), One Tree Hill'', ''House (TV series), House'', ''Harper's Island'', ''Jericho (2006 TV series), Jericho'', ''White Collar (TV series), White Collar'', ''Fastlane (TV series), Fastlane'' and ''Bones (TV series), Bones''. Personal life Bookstaver married act ...
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Amber Tamblyn
Amber Rose Tamblyn (born May 14, 1983) is an American actress and writer. She first came to national attention in her role on the soap opera ''General Hospital'' as Emily Quartermaine at the age of 11. She followed with a starring role on the prime-time series '' Joan of Arcadia'', portraying the title character, Joan Girardi, for which she received Primetime Emmy and Golden Globe nominations. Her feature film work includes roles such as Tibby Rollins from the first two ''The Sisterhood of the Traveling Pants'' and Megan McBride in '' 127 Hours'' (2010), as well as the critically acclaimed film, '' Stephanie Daley'' opposite Tilda Swinton which debuted at The Sundance Film Festival and for which Tamblyn won Best Actress at The Locarno International Film Festival and was nominated for an Independent Spirit Award. In 2021 she starred opposite Diane Lane in FX's '' Y: The Last Man''. Tamblyn is a published author and cultural critic at large. She has published seven books across ...
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