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NovoGen
NovoGen is a proprietary form of 3D printing technology that allows scientists to assemble living tissue cells into a desired pattern. When combined with an extracellular matrix In biology, the extracellular matrix (ECM), also called intercellular matrix, is a three-dimensional network consisting of extracellular macromolecules and minerals, such as collagen, enzymes, glycoproteins and hydroxyapatite that provide s ..., the cells can be arranged into complex structures, such as organs. Designed by Organovo, the NovoGen technology has been successfully integrated by Invetech with a production printer that is intended to help develop processes for tissue repair and organ development. References Developmental biology 3D printing processes American inventions Synthetic biology {{comp-sci-stub ...
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Organovo
Organovo is an early-stage medical laboratory and research company which designs and develops functional, three dimensional human tissue (also known as 3D bioprinting technology) for medical research and therapeutic applications. Organovo was established in 2007 and is headquartered in San Diego, California. The company uses its internally developed NovoGen MMX Bioprinter for 3D bioprinting.. Operations The company bioprints and markets human tissues as a means of accelerating the preclinical drug testing and discovery process, enabling treatments to be created more quickly and at lower cost, and without immediate risks to living test subjects. Organovo has long-term expectations that this technology could be suitable for surgical therapy and transplantation. Organovo also partners with biopharmaceutical companies and academic medical centers to design, build, and validate more predictive ''in vitro'' tissues for disease modeling and toxicology. The living test tissues provide ...
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3D Printing
3D printing or additive manufacturing is the construction of a three-dimensional object from a CAD model or a digital 3D model. It can be done in a variety of processes in which material is deposited, joined or solidified under computer control, with material being added together (such as plastics, liquids or powder grains being fused), typically layer by layer. In the 1980s, 3D printing techniques were considered suitable only for the production of functional or aesthetic prototypes, and a more appropriate term for it at the time was rapid prototyping. , the precision, repeatability, and material range of 3D printing have increased to the point that some 3D printing processes are considered viable as an industrial-production technology, whereby the term ''additive manufacturing'' can be used synonymously with ''3D printing''. One of the key advantages of 3D printing is the ability to produce very complex shapes or geometries that would be otherwise impossible to construct ...
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Extracellular Matrix
In biology, the extracellular matrix (ECM), also called intercellular matrix, is a three-dimensional network consisting of extracellular macromolecules and minerals, such as collagen, enzymes, glycoproteins and hydroxyapatite that provide structural and biochemical support to surrounding cells. Because multicellularity evolved independently in different multicellular lineages, the composition of ECM varies between multicellular structures; however, cell adhesion, cell-to-cell communication and differentiation are common functions of the ECM. The animal extracellular matrix includes the interstitial matrix and the basement membrane. Interstitial matrix is present between various animal cells (i.e., in the intercellular spaces). Gels of polysaccharides and fibrous proteins fill the interstitial space and act as a compression buffer against the stress placed on the ECM. Basement membranes are sheet-like depositions of ECM on which various epithelial cells rest. Each type ...
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Organ (anatomy)
In biology, an organ is a collection of tissues joined in a structural unit to serve a common function. In the hierarchy of life, an organ lies between tissue and an organ system. Tissues are formed from same type cells to act together in a function. Tissues of different types combine to form an organ which has a specific function. The intestinal wall for example is formed by epithelial tissue and smooth muscle tissue. Two or more organs working together in the execution of a specific body function form an organ system, also called a biological system or body system. An organ's tissues can be broadly categorized as parenchyma, the functional tissue, and stroma, the structural tissue with supportive, connective, or ancillary functions. For example, the gland's tissue that makes the hormones is the parenchyma, whereas the stroma includes the nerves that innervate the parenchyma, the blood vessels that oxygenate and nourish it and carry away its metabolic wastes, and the con ...
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Westwick-Farrow Media
Universal Magazines (now Universal Media Co.) is an Australian publisher of magazines, websites, and calendar products that cater to niche market A niche market is the subset of the market on which a specific product is focused. The market niche defines the product features aimed at satisfying specific market needs, as well as the price range, production quality and the demographics that i ...s. Prema Perera is currently CEO of the company. In 2018, Universal Magazines rebranded as Universal Media Co, taking into account the increasing importance of online and new media in their business model. In 2019, Universal Magazines sold Pool+Spa to the Swimming Pool and Spa Association of Australia. Media brands Home Lifestyle Motorbike Craft B2B * ''Outdoor Design Source'' * ''outdoordesign.com.au'' References External links Universal Media Co websiteUniversal Shop (Subscription site) Magazine publishing companies of Australia 1986 establishments in Australia Publishi ...
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Developmental Biology
Developmental biology is the study of the process by which animals and plants grow and develop. Developmental biology also encompasses the biology of regeneration, asexual reproduction, metamorphosis, and the growth and differentiation of stem cells in the adult organism. Perspectives The main processes involved in the embryonic development of animals are: tissue patterning (via regional specification and patterned cell differentiation); tissue growth; and tissue morphogenesis. * Regional specification refers to the processes that create the spatial patterns in a ball or sheet of initially similar cells. This generally involves the action of cytoplasmic determinants, located within parts of the fertilized egg, and of inductive signals emitted from signaling centers in the embryo. The early stages of regional specification do not generate functional differentiated cells, but cell populations committed to developing to a specific region or part of the organism. These a ...
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3D Printing Processes
A variety of processes, equipment, and materials are used in the production of a three-dimensional object via additive manufacturing. 3D printing is also known as additive manufacturing, therefore the numerous available 3D printing process tend to be additive in nature with a few key differences in the technologies and the materials used in this process. Some of the different types of physical transformations which are used in 3D printing include melt extrusion, light polymerization, continuous liquid interface production and sintering. Types of 3D printing processes There are many different 3D printing processes, that can be grouped into seven categories: * Vat photopolymerization * Material jetting * Binder jetting * Powder bed fusion * Material extrusion * Directed energy deposition * Sheet lamination Each process and piece of equipment has pros and cons associated with it. These usually involve aspects such as speed, costs, versatility with respect to feedstock ma ...
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American Inventions
The following articles cover the timeline of United States inventions: * Timeline of United States inventions (before 1890), before the turn of the century * Timeline of United States inventions (1890–1945), before World War II * Timeline of United States inventions (1946–1991), for the post-war era * Timeline of United States inventions (after 1991), after the Fall of the Soviet Union {{DEFAULTSORT:Timeline of United States Inventions United States inventions United States The United States of America (U.S.A. or USA), commonly known as the United States (U.S. or US) or America, is a country Continental United States, primarily located in North America. It consists of 50 U.S. state, states, a Washington, D.C., ...
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