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Norman Heatley
Norman George Heatley OBE (10 January 1911 – 5 January 2004) was an English biologist and biochemist. He was a member of the team of Oxford University scientists who developed penicillin. Norman Heatley developed the back-extraction technique for efficiently purifying penicillin in bulk. Early life He was born in Woodbridge, Suffolk, and as a boy was an enthusiastic sailor of a small boat on the River Deben, an experience which gave him a lifelong love of sailing. He attended school in Folkestone, followed by Tonbridge School, then went on to St John's College, Cambridge, where he studied Natural Sciences, graduating in 1933. His doctoral research in Cambridge led to a PhD in 1936, and he then moved to the University of Oxford, where he became a fellow of Lincoln College and joined a team working under Howard Florey that included Ernst Chain. Production problem Alexander Fleming had first discovered penicillin by accident in 1928, but at that time believed it had little ap ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Woodbridge, Suffolk
Woodbridge is a port and market town in the East Suffolk District, East Suffolk district of Suffolk, England. It is up the River Deben from the sea. It lies north-east of Ipswich and forms part of the wider Ipswich built-up area. The town is close to some major archaeological sites of the Anglo-Saxons, Anglo-Saxon period, including the Sutton Hoo burial ship, and had 35 households at the time of the ''Domesday Book'' of 1086. It is well known for its boating harbour and tide mill, on the edge of the Suffolk Coast and Heath Area of Outstanding Natural Beauty. Several festivals are held. As a "gem in Suffolk's crown", it has been named the best place to live in the East of England. Etymology Historians disagree over the etymology of Woodbridge. ''The Dictionary of British Placenames'' suggests that it is a combination of the Old English wudu (wood) and brycg (bridge). However in the Sutton Hoo Societies' magazine ''Saxon'' points out that is no suitable site for a bridge at Woodb ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Howard Florey
Howard Walter Florey, Baron Florey (24 September 189821 February 1968) was an Australian pharmacologist and pathologist who shared the Nobel Prize in Physiology or Medicine in 1945 with Sir Ernst Chain and Sir Alexander Fleming for his role in the development of penicillin. Although Fleming received most of the credit for the discovery of penicillin, it was Florey who carried out the first clinical trials of penicillin in 1941 at the Radcliffe Infirmary in Oxford on the first patient, a police constable from Oxford. The patient started to recover, but subsequently died because Florey was unable, at that time, to make enough penicillin. It was Florey and Chain who actually made a useful and effective drug out of penicillin, after the task had been abandoned as too difficult. Florey's discoveries, along with the discoveries of Fleming and Ernst Chain, are estimated to have saved over 200 million lives, and he is consequently regarded by the Australian scientific and medical comm ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Thomson Scientific
Thomson Scientific was one of the six (later five) strategic business units of The Thomson Corporation, beginning in 2007, after being separated from Thomson Scientific & Healthcare. Following the merger of Thomson with Reuters Group to form Thomson Reuters in 2008, it became the "Scientific" business unit of the new company. In 2009, the unit came together with the Healthcare division of Thomson Reuters to form the Healthcare & Science division. The healthcare business was sold in 2012 to become Truven Health Analytics. The Science unit of Thomson Reuters provided information services for the academic, business, and R&D communities. It had headquarters in Philadelphia, London, Singapore and Tokyo with about 2,400 staff in more than 20 countries. Its products were Aureka, Delphion, Cortellis, Derwent World Patents Index (DWPI), EndNote, Horizon Global, Horizon Sourcing, IDdb, IDRAC, IP Management Services, ISI Web of Knowledge, MicroPatent PatentWeb, Techstreet Industry Standards, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Septicaemia
Sepsis, formerly known as septicemia (septicaemia in British English) or blood poisoning, is a life-threatening condition that arises when the body's response to infection causes injury to its own tissues and organs. This initial stage is followed by suppression of the immune system. Common signs and symptoms include fever, increased heart rate, increased breathing rate, and confusion. There may also be symptoms related to a specific infection, such as a cough with pneumonia, or painful urination with a kidney infection. The very young, old, and people with a weakened immune system may have no symptoms of a specific infection, and the body temperature may be low or normal instead of having a fever. Severe sepsis causes poor organ function or blood flow. The presence of low blood pressure, high blood lactate, or low urine output may suggest poor blood flow. Septic shock is low blood pressure due to sepsis that does not improve after fluid replacement. Sepsis is caused by m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Spine (botany)
In plant morphology, thorns, spines, and prickles, and in general spinose structures (sometimes called ''spinose teeth'' or ''spinose apical processes''), are hard, rigid extensions or modifications of leaves, roots, stems or buds with sharp, stiff ends, and generally serve the same function: physically deterring animals from eating the plant material. Description In common language the terms are used more or less interchangeably, but in botanical terms, thorns are derived shoots (so that they may or may not be branched, they may or may not have leaves, and they may or may not arise from a bud),Simpson, M. G. 2010. "Plant Morphology". In: ''Plant Systematics, 2nd. edition''. Elsevier Academic Press. Chapter 9.Judd, Campbell, Kellogg, Stevens, Donoghue. 2007. "Structural and Biochemical Characters". In: ''Plant Systematics, a phylogenetic approach, third edition''. Chapter 4. spines are derived from leaves (either the entire leaf or some part of the leaf that has vascular bundles ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Albert Alexander (police Officer)
Reserve Constable Albert Alexander (1896 – 15 March 1941) was the first patient to be treated with injections of penicillin. Albert Alexander was a constable in the police force of the County of Oxford, England. A bombing raid is likely the cause of the injuries sustained by Constable Alexander that was to become the source of his bacterial infection, rather than what became the prevailing narrative, a scratch by a rose thorn on his face. Alexander became badly infected with both ''Staphylococcus'' and ''Streptococcus'' and Constable Alexander was hospitalised in the Radcliffe Infirmary. Despite efforts of various treatments, Alexander's head was covered with abscesses and one of his eyes had been removed. Dr Ethel Florey, lab partner and wife of pharmacologist and medic Dr Howard Walter Florey, and Dr Charles Fletcher brought Constable Alexander's case to Florey's attention. The ability of penicillin to slow or counteract bacterial infection had first been noticed by Sir ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Staffordshire Potteries
The Staffordshire Potteries is the industrial area encompassing the six towns Burslem, Fenton, Hanley, Longton, Stoke and Tunstall, which is now the city of Stoke-on-Trent in Staffordshire, England. North Staffordshire became a centre of ceramic production in the early 17th century, Fleming, John & Hugh Honour. (1977) ''The Penguin Dictionary of Decorative Arts. '' London: Allen Lane, p. 752. due to the local availability of clay, salt, lead and coal. Spread Hundreds of companies produced all kinds of pottery, from tablewares and decorative pieces to industrial items. The main pottery types of earthenware, stoneware and porcelain were all made in large quantities, and the Staffordshire industry was a major innovator in developing new varieties of ceramic bodies such as bone china and jasperware, as well as pioneering transfer printing and other glazing and decorating techniques. In general Staffordshire was strongest in the middle and low price ranges, though the finest an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
World War II
World War II or the Second World War, often abbreviated as WWII or WW2, was a world war that lasted from 1939 to 1945. It involved the vast majority of the world's countries—including all of the great powers—forming two opposing military alliances: the Allies and the Axis powers. World War II was a total war that directly involved more than 100 million personnel from more than 30 countries. The major participants in the war threw their entire economic, industrial, and scientific capabilities behind the war effort, blurring the distinction between civilian and military resources. Aircraft played a major role in the conflict, enabling the strategic bombing of population centres and deploying the only two nuclear weapons ever used in war. World War II was by far the deadliest conflict in human history; it resulted in 70 to 85 million fatalities, mostly among civilians. Tens of millions died due to genocides (including the Holocaust), starvation, ma ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Radcliffe Infirmary
The Radcliffe Infirmary was a hospital in central north Oxford, England, located at the southern end of Woodstock Road on the western side, backing onto Walton Street. History The initial proposals to build a hospital in Oxford were put forward at a meeting of the Radcliffe Trustees, who were administering John Radcliffe's estate valued at £4,000, in 1758. The facility was constructed on land given by Thomas Rowney, one of the two members of parliament for Oxford. The foundation stone was laid on 27 August 1761 and the new facility was officially opened on 18 October 1770. A fountain of the Greek god Triton was placed in front of the main infirmary building in 1858 and the Oxford Eye Hospital was established on the site in 1886.A brief history of the Nuffield Laboratory of Ophthalmology ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bedpan
A bedpan or bed pan is a receptacle used for the toileting of a bedridden patient in a health care facility, and is usually made of metal, glass, ceramic, or plastic. A bedpan can be used for both urinary and fecal discharge. Many diseases can confine a patient to bed, necessitating the use of bedpans, including Alzheimer's disease, Parkinson's disease, stroke, and dementia. Additionally, many patients may be confined to a bed temporarily as a result of a temporary illness, injury, or surgery. Bedpans are usually constructed of stainless steel, which is easy to clean and durable, but may be cold, hard, and uncomfortable to use. Also, the supporting area of some products is very small, and prolonged use can cause pressure ulcers. To solve these problems, ergonomic bedpans have been developed, which support the patient with a larger area of less-conductive plastic. Some designs completely cover the genitalia during use, offering protection and an extra measure of privacy. On the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Drug
A drug is any chemical substance that causes a change in an organism's physiology or psychology when consumed. Drugs are typically distinguished from food and substances that provide nutritional support. Consumption of drugs can be via insufflation (medicine), inhalation, drug injection, injection, smoking, ingestion, absorption (skin), absorption via a dermal patch, patch on the skin, suppository, or sublingual administration, dissolution under the tongue. In pharmacology, a drug is a chemical substance, typically of known structure, which, when administered to a living organism, produces a biological effect. A pharmaceutical drug, also called a medication or medicine, is a chemical substance used to pharmacotherapy, treat, cure, preventive healthcare, prevent, or medical diagnosis, diagnose a disease or to promote well-being. Traditionally drugs were obtained through extraction from medicinal plants, but more recently also by organic synthesis. Pharmaceutical drugs may be used ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mouse
A mouse ( : mice) is a small rodent. Characteristically, mice are known to have a pointed snout, small rounded ears, a body-length scaly tail, and a high breeding rate. The best known mouse species is the common house mouse (''Mus musculus''). Mice are also popular as pets. In some places, certain kinds of field mice are locally common. They are known to invade homes for food and shelter. Mice are typically distinguished from rats by their size. Generally, when a muroid rodent is discovered, its common name includes the term ''mouse'' if it is smaller, or ''rat'' if it is larger. The common terms ''rat'' and ''mouse'' are not taxonomically specific. Typical mice are classified in the genus '' Mus'', but the term ''mouse'' is not confined to members of ''Mus'' and can also apply to species from other genera such as the deer mouse, ''Peromyscus''. Domestic mice sold as pets often differ substantially in size from the common house mouse. This is attributable to breeding a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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