Nootkatone
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Nootkatone
Nootkatone is a natural organic compound, a sesquiterpenoid, and a ketone that is the most important and expensive aromatic of grapefruit, and which also occurs in other organisms. Previously, nootkatone was thought to be one of the main chemical components of the smell and flavour of grapefruits. In high purity, it usually is found as colorless crystals. Crude extractives are liquid, viscous, and yellow. Nootkatone typically is extracted from grapefruit through the chemical or biochemical oxidation of valencene. It is found in Alaska yellow cedar trees, as well as in vetiver grass. Mechanism of action As is true of other plant terpenoids, nootkatone activates α-adrenergic type 1 octopamine receptor (PaOA1) in susceptible arthropods, causing fatal spasms. Natural origin Nootkatone was isolated from the wood of the Alaskan yellow cedar, ''Cupressus nootkatensis''. The species name, nootkatensis, is derived from the language of the Nuu-Chah-Nulth people of Canada (formerly ...
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Insecticide
Insecticides are substances used to kill insects. They include ovicides and larvicides used against insect eggs and larvae, respectively. Insecticides are used in agriculture, medicine, industry and by consumers. Insecticides are claimed to be a major factor behind the increase in the 20th-century's agricultural productivity. Nearly all insecticides have the potential to significantly alter ecosystems; many are toxic to humans and/or animals; some become concentrated as they spread along the food chain. Insecticides can be classified into two major groups: systemic insecticides, which have residual or long term activity; and contact insecticides, which have no residual activity. The mode of action describes how the pesticide kills or inactivates a pest. It provides another way of classifying insecticides. Mode of action can be important in understanding whether an insecticide will be toxic to unrelated species, such as fish, birds and mammals. Insecticides may be repellen ...
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Valencene
Valencene is a sesquiterpene that is an aroma component of citrus fruit and citrus-derived odorants. It is obtained inexpensively from Valencia oranges. Valencene is biosynthesized from farnesyl pyrophosphate (FPP) by the CVS enzyme. It is a precursor to nootkatone Nootkatone is a natural organic compound, a sesquiterpenoid, and a ketone that is the most important and expensive aromatic of grapefruit, and which also occurs in other organisms. Previously, nootkatone was thought to be one of the main chemic ..., the main contributor to the aroma and flavor of grapefruit and is often used in insecticides, cleaning, personal care products and cosmetics. References {{Terpenes Sesquiterpenes Decalins Alkene derivatives Cyclohexenes ...
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Grapefruit Mercaptan
Grapefruit mercaptan is the common name for a natural organic compound found in grapefruit. It is a monoterpenoid that contains a thiol (also known as a mercaptan) functional group. Structurally a hydroxy group of terpineol is replaced by the thiol in grapefruit mercaptan, so it also called thioterpineol. Volatile thiols typically have very strong, often unpleasant odors that can be detected by humans in very low concentrations. Grapefruit mercaptan has a very potent, but not unpleasant, odor, and it is the chemical constituent primarily responsible for the aroma of grapefruit. This characteristic aroma is a property of only the ''R'' enantiomer. Pure grapefruit mercaptan, or citrus-derived oils rich in grapefruit mercaptan, are sometimes used in perfumery and the flavor industry to impart citrus aromas and flavors. However, both industries actively seek substitutes for grapefruit mercaptans for use as a grapefruit flavorant, since its decomposition products are often highly ...
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Valencene
Valencene is a sesquiterpene that is an aroma component of citrus fruit and citrus-derived odorants. It is obtained inexpensively from Valencia oranges. Valencene is biosynthesized from farnesyl pyrophosphate (FPP) by the CVS enzyme. It is a precursor to nootkatone Nootkatone is a natural organic compound, a sesquiterpenoid, and a ketone that is the most important and expensive aromatic of grapefruit, and which also occurs in other organisms. Previously, nootkatone was thought to be one of the main chemic ..., the main contributor to the aroma and flavor of grapefruit and is often used in insecticides, cleaning, personal care products and cosmetics. References {{Terpenes Sesquiterpenes Decalins Alkene derivatives Cyclohexenes ...
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Arthropods
Arthropods (, (gen. ποδός)) are invertebrate animals with an exoskeleton, a segmented body, and paired jointed appendages. Arthropods form the phylum Arthropoda. They are distinguished by their jointed limbs and cuticle made of chitin, often mineralised with calcium carbonate. The arthropod body plan consists of segments, each with a pair of appendages. Arthropods are bilaterally symmetrical and their body possesses an external skeleton. In order to keep growing, they must go through stages of moulting, a process by which they shed their exoskeleton to reveal a new one. Some species have wings. They are an extremely diverse group, with up to 10 million species. The haemocoel, an arthropod's internal cavity, through which its haemolymph – analogue of blood – circulates, accommodates its interior organs; it has an open circulatory system. Like their exteriors, the internal organs of arthropods are generally built of repeated segments. Their nervous system is " ...
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Sesquiterpenes
Sesquiterpenes are a class of terpenes that consist of three isoprene units and often have the molecular formula C15H24. Like monoterpenes, sesquiterpenes may be cyclic or contain rings, including many unique combinations. Biochemical modifications such as oxidation or rearrangement produce the related sesquiterpenoids. Sesquiterpenes are found naturally in plants and insects, as semiochemicals, e.g. defensive agents or pheromones. Biosynthesis and examples The reaction of geranyl pyrophosphate with isopentenyl pyrophosphate results in the 15-carbon farnesyl pyrophosphate (FPP), which is an intermediate in the biosynthesis of sesquiterpenes such as farnesene. Cyclic sesquiterpenes are more common than cyclic monoterpenes because of the increased chain length and additional double bond in the sesquiterpene precursors. In addition to common six-membered ring systems such as the ones found in zingiberene and bisacurone, cyclization of one end of the chain to the other end ca ...
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Flavors
Flavor or flavour is either the sensory perception of taste or smell, or a flavoring in food that produces such perception. Flavor or flavour may also refer to: Science *Flavors (programming language), an early object-oriented extension to Lisp * Flavour (particle physics), a quantum number of elementary particles related to their weak interactions *Flavor of Linux, another term for any particular Linux distribution; by extension, "flavor" can be applied to any program or other computer code that exists in more than one current variant at the same time Film and TV * ''Flavors'' (film), romantic comedy concerning Asian-Indian immigrants in America Music Artists and bands * Flavor Flav (born 1959), former rap/hip-hop promoter and current reality television actor * Flavour N'abania (born 1983), Nigerian singer-songwriter * Flavor (band), minor hit with "Sally Had A Party" in 1968 Albums * ''Flavours'' (album), 1975 album by The Guess Who * ''Flavors'' (album), by American ...
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Centers For Disease Control And Prevention
The Centers for Disease Control and Prevention (CDC) is the national public health agency of the United States. It is a United States federal agency, under the Department of Health and Human Services, and is headquartered in Atlanta, Georgia. The agency's main goal is the protection of public health and safety through the control and prevention of disease, injury, and disability in the US and worldwide. The CDC focuses national attention on developing and applying disease control and prevention. It especially focuses its attention on infectious disease, food borne pathogens, environmental health, occupational safety and health, health promotion, injury prevention and educational activities designed to improve the health of United States citizens. The CDC also conducts research and provides information on non-infectious diseases, such as obesity and diabetes, and is a founding member of the International Association of National Public Health Institutes.
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Amblyomma Americanum
''Amblyomma americanum'', also known as the lone star tick, the northeastern water tick, or the turkey tick, or the "Cricker Tick", is a type of tick indigenous to much of the eastern United States and Mexico, that bites painlessly and commonly goes unnoticed, remaining attached to its host for as long as seven days until it is fully engorged with blood. It is a member of the phylum Arthropoda, class Arachnida. The adult lone star tick is sexually dimorphic, named for a silvery-white, star-shaped spot or "lone star" present near the center of the posterior portion of the adult female shield (scutum); adult males conversely have varied white streaks or spots around the margins of their shields. ''A. americanum'' is also referred to as the turkey tick in some Midwestern U.S. states, where wild turkeys are a common host for immature ticks. It is the primary vector of ''Ehrlichia chaffeensis'', which causes human monocytic ehrlichiosis, and ''Ehrlichia ewingii'', which causes human ...
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Ixodes Scapularis
''Ixodes scapularis'' is commonly known as the deer tick or black-legged tick (although some people reserve the latter term for '' Ixodes pacificus'', which is found on the west coast of the US), and in some parts of the US as the bear tick. It was also named ''Ixodes dammini'' until it was shown to be the same species in 1993. It is a hard-bodied tick found in the eastern and northern Midwest of the United States as well as in southeastern Canada. It is a vector for several diseases of animals, including humans (Lyme disease, babesiosis, anaplasmosis, Powassan virus disease, etc.) and is known as the deer tick owing to its habit of parasitizing the white-tailed deer. It is also known to parasitize mice, lizards, migratory birds, etc. especially while the tick is in the larval or nymphal stage. Description The image shown here—and in fact, most images of ''Ixodes scapularis'' that are commonly available—show an adult female that is unengorged, that is, an adult female that ...
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Nuu-Chah-Nulth
The Nuu-chah-nulth (; Nuučaan̓uł: ), also formerly referred to as the Nootka, Nutka, Aht, Nuuchahnulth or Tahkaht, are one of the indigenous peoples of the Pacific Northwest Coast in Canada. The term Nuu-chah-nulth is used to describe fifteen related tribes whose traditional home is on the west coast of Vancouver Island. In precontact and early post-contact times, the number of tribes was much greater, but the smallpox epidemics and other consequences of settler colonization resulted in the disappearance of some groups and the absorption of others into neighbouring groups. The Nuu-chah-nulth are related to the Kwakwaka'wakw, the Haisla, and the Ditidaht First Nation. The Nuu-chah-nulth language belongs to the Wakashan family. The governing body is the Nuu-chah-nulth Tribal Council. History Contact with Europeans When James Cook first encountered the villagers at Yuquot in 1778, they directed him to "come around" (Nuu-chah-nulth ''nuutkaa'' is "to circle around")Camp ...
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