Nir Barzilai
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Nir Barzilai
Nir Barzilai is the founding director of the Institute for Aging Research, the Nathan Shock Center of Excellence in the Basic Biology of Aging and the Paul F. Glenn Center for the Biology of Human Aging Research at Albert Einstein College of Medicine (Einstein). He also directs the Longevity Genes Project, a genetics study of over 600 families of centenarians and their children. The participants are all Ashkenazi Jews, a group selected for their genetic homogeneity, which makes it easier to identify significant genetic variations. Barzilai found that many of the centenarians had very high levels of HDL. Barzilai also co-founded of CohBar, Inc., a biotechnology company developing mitochondria based therapeutics to treat diseases associated with aging. Barzilai discovered several “ longevity genes” in humans that were validated by others. These include variants in genes involved in cholesterol metabolism (CETP and APOC3 ), metabolism ( ADIPOQ and TSHR) and growth (IGF1R). These ...
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Albert Einstein College Of Medicine
Albert Einstein College of Medicine is a research-intensive medical school located in the Morris Park neighborhood of the Bronx in New York City. Founded in 1953, Einstein operates as an independent degree-granting institution as part of the integrated health care system, Montefiore Health System (Montefiore Medicine), which includes affiliates such as Jacobi Medical Center. Admission to Einstein is highly competitive, with one of the lowest acceptance rates among medical schools in the United States (3.3% in 2021). Einstein ranks 13th among top U.S. medical schools for graduate success in academic medicine and biomedical research (i.e., awards, publications, grants, and clinical trials), and its NIH funding per investigator consistently ranks among the highest in the nation (7th among US universities in 2019). Einstein offers a M.D. program, a Ph.D. program in the biomedical sciences and clinical investigation, and two Master of Science (M.S.) degrees. In 2021, the MD pro ...
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Metformin
Metformin, sold under the brand name Glucophage, among others, is the main first-line medication for the treatment of type 2 diabetes, particularly in people who are overweight. It is also used in the treatment of polycystic ovary syndrome. It is not associated with weight gain and is taken by mouth. It is sometimes used as an off-label adjunct to lessen the risk of metabolic syndrome in people who take antipsychotics. Metformin is generally well tolerated. Common adverse effects include diarrhea, nausea, and abdominal pain. It has a small risk of causing low blood sugar. High blood lactic acid level is a concern if the medication is used in overly large doses or prescribed in people with severe kidney problems. It is not recommended in those with significant liver disease. Metformin is a biguanide antihyperglycemic agent. It works by decreasing glucose production in the liver, increasing the insulin sensitivity of body tissues, and increasing GDF15 secretion, which redu ...
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Israeli Geneticists
Israeli may refer to: * Something of, from, or related to the State of Israel * Israelis, citizens or permanent residents of the State of Israel * Modern Hebrew, a language * ''Israeli'' (newspaper), published from 2006 to 2008 * Guni Israeli (born 1984), Israeli basketball player See also * Israelites, the ancient people of the Land of Israel * List of Israelis Israelis ( he, ישראלים ''Yiśraʾelim'') are the citizens or permanent residents of the State of Israel, a multiethnic state populated by people of different ethnic backgrounds. The largest ethnic groups in Israel are Jews (75%), foll ... {{disambiguation Language and nationality disambiguation pages ...
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Living People
Related categories * :Year of birth missing (living people) / :Year of birth unknown * :Date of birth missing (living people) / :Date of birth unknown * :Place of birth missing (living people) / :Place of birth unknown * :Year of death missing / :Year of death unknown * :Date of death missing / :Date of death unknown * :Place of death missing / :Place of death unknown * :Missing middle or first names See also * :Dead people * :Template:L, which generates this category or death years, and birth year and sort keys. : {{DEFAULTSORT:Living people 21st-century people People by status ...
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Endocrinology
Endocrinology (from '' endocrine'' + '' -ology'') is a branch of biology and medicine dealing with the endocrine system, its diseases, and its specific secretions known as hormones. It is also concerned with the integration of developmental events proliferation, growth, and differentiation, and the psychological or behavioral activities of metabolism, growth and development, tissue function, sleep, digestion, respiration, excretion, mood, stress, lactation, movement, reproduction, and sensory perception caused by hormones. Specializations include behavioral endocrinology and comparative endocrinology. The endocrine system consists of several glands, all in different parts of the body, that secrete hormones directly into the blood rather than into a duct system. Therefore, endocrine glands are regarded as ductless glands. Hormones have many different functions and modes of action; one hormone may have several effects on different target organs, and, conversely, one target orga ...
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Yale University
Yale University is a private research university in New Haven, Connecticut. Established in 1701 as the Collegiate School, it is the third-oldest institution of higher education in the United States and among the most prestigious in the world. It is a member of the Ivy League. Chartered by the Connecticut Colony, the Collegiate School was established in 1701 by clergy to educate Congregational ministers before moving to New Haven in 1716. Originally restricted to theology and sacred languages, the curriculum began to incorporate humanities and sciences by the time of the American Revolution. In the 19th century, the college expanded into graduate and professional instruction, awarding the first PhD in the United States in 1861 and organizing as a university in 1887. Yale's faculty and student populations grew after 1890 with rapid expansion of the physical campus and scientific research. Yale is organized into fourteen constituent schools: the original undergraduate col ...
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London
London is the capital and largest city of England and the United Kingdom, with a population of just under 9 million. It stands on the River Thames in south-east England at the head of a estuary down to the North Sea, and has been a major settlement for two millennia. The City of London, its ancient core and financial centre, was founded by the Romans as '' Londinium'' and retains its medieval boundaries.See also: Independent city § National capitals The City of Westminster, to the west of the City of London, has for centuries hosted the national government and parliament. Since the 19th century, the name "London" has also referred to the metropolis around this core, historically split between the counties of Middlesex, Essex, Surrey, Kent, and Hertfordshire, which largely comprises Greater London, governed by the Greater London Authority.The Greater London Authority consists of the Mayor of London and the London Assembly. The London Mayor is distinguished fr ...
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Royal Free Hospital
The Royal Free Hospital (also known simply as the Royal Free) is a major teaching hospital in the Hampstead area of the London Borough of Camden. The hospital is part of the Royal Free London NHS Foundation Trust, which also runs services at Barnet Hospital, Chase Farm Hospital and a number of other sites. The trust is a founder member of the UCLPartners academic health science centre. History Early history What became the Royal Free Hospital was founded in 1828 by the surgeon William Marsden to provide free care to those of little means. It is said that one evening, Marsden found a young girl lying on the steps of St. Andrew Church, Holborn, dying from disease and hunger and sought help for her from one of the nearby hospitals. However, none would take the girl in and she died two days later. After this experience Marsden set up a small dispensary at 16 Greville Street, Holborn, called the London General Institution for the Gratuitous Care of Malignant Diseases. The hospita ...
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Hadassah Medical Center
Hadassah Medical Center ( he, הָמֶרְכָּז הָרְפוּאִי הֲדַסָּה) is an Israeli medical organization established in 1934 that operates two university hospitals in Jerusalem – one in Ein Karem and one in Mount Scopus –, as well as schools of medicine, dentistry, nursing, and pharmacology affiliated with the Hebrew University of Jerusalem. Its declared mission is to extend a "hand to all, without regard for race, religion or ethnic origin." The hospital was founded by the Hadassah Women's Zionist Organization of America, which continues to underwrite a large part of its budget today. The Medical Center ranks as the sixth-largest hospital complex in Israel. Across its two campuses, Hadassah Medical Center has over 1,300 beds, 31 operating theaters and nine special intensive care units, and runs five schools of medical professions. History Late Ottoman period (1912–1915) The Hadassah organization was established in 1912 in New York City to provide heal ...
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Rambam Health Care Campus
Rambam Health Care Campus ( he, רמב"ם - הקריה הרפואית לבריאות האדם) commonly called Rambam Hospital, is a teaching hospital in the Bat Galim neighborhood of Haifa, Israel founded in 1938, 10 years before the establishment of the State of Israel. It is the largest medical center in northern Israel and fifth largest in Israel, and is named for the 12th century physician-philosopher Rabbi Moshe Ben-Maimon (Maimonides), known as the Rambam. Rambam Health Care Campus is also an academic teaching hospital affiliated with the Rappaport Faculty of Medicine of the Technion – Israel Institute of Technology, Israel's oldest university. Facilities Rambam Hospital serves as a referral medical center and Level I trauma center, employing a multidisciplinary approach to diagnosis and treatment. Some 80,000 people are hospitalized there every year, and another 600,000 are treated in its outpatient clinics and medical institutes. The Technion's medical school is l ...
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Technion – Israel Institute Of Technology
The Technion – Israel Institute of Technology ( he, הטכניון – מכון טכנולוגי לישראל) is a public research university located in Haifa, Israel. Established in 1912 under the dominion of the Ottoman Empire, the Technion is the oldest university in the country. The Technion is ranked as one of the top universities in both Israel and the Middle East, and in the world's top 100 universities in the 2022 Academic Ranking of World Universities. The university offers degrees in science and engineering, and related fields such as architecture, medicine, industrial management, and education. It has 19 academic departments, 60 research centers, and 12 affiliated teaching hospitals. Since its founding, it has awarded more than 123,000 degrees and its graduates are cited for providing the skills and education behind the creation and protection of the State of Israel. Technion's 565 faculty members include three Nobel Laureates in chemistry. Four Nobel Laureates ha ...
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Operation Entebbe
Operation Entebbe, also known as the Entebbe Raid or Operation Thunderbolt, was a counter-terrorist hostage-rescue mission carried out by commandos of the Israel Defense Forces (IDF) at Entebbe Airport in Uganda on 4 July 1976. A week earlier, on 27 June, an Air France Airbus A300 jet airliner with 248 passengers had been hijacked by two members of the Popular Front for the Liberation of Palestine – External Operations (PFLP-EO) under orders of Wadie Haddad (who had earlier broken away from the PFLP of George Habash), and two members of the German Revolutionary Cells. The hijackers had the stated objective to free 40 Palestinian and affiliated militants imprisoned in Israel and 13 prisoners in four other countries in exchange for the hostages. The flight, which had originated in Tel Aviv with the destination of Paris, was diverted after a stopover in Athens via Benghazi to Entebbe, the main airport of Uganda. The Ugandan government supported the hijackers, and dictator I ...
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