N100
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N100
In neuroscience, the N100 or N1 is a large, negative-going evoked potential measured by electroencephalography (its equivalent in magnetoencephalography is the M100); it peaks in adults between 80 and 120 milliseconds after the onset of a stimulus, and is distributed mostly over the fronto-central region of the scalp. It is elicited by any unpredictable stimulus in the absence of task demands. It is often referred to with the following P200 evoked potential as the "N100-P200" or "N1-P2" complex. While most research focuses on auditory stimuli, the N100 also occurs for visual (see visual N1, including an illustration), olfactory, heat, pain, balance, respiration blocking, and somatosensory stimuli. The auditory N100 is generated by a network of neural populations in the primary and association auditory cortices in the superior temporal gyrus in Heschl's gyrus and planum temporale. It also could be generated in the frontal and motor areas. The area generating it is larger i ...
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Visual N1
The visual N1 is a visual evoked potential, a type of event-related electrical potential (ERP), that is produced in the brain and recorded on the scalp. The N1 is so named to reflect the polarity and typical timing of the component. The "N" indicates that the polarity of the component is negative with respect to an average mastoid reference. The "1" originally indicated that it was the first negative-going component, but it now better indexes the typical peak of this component, which is around 150 to 200 milliseconds post-stimulus. The N1 deflection may be detected at most recording sites, including the occipital, parietal, central, and frontal electrode sites.Mangun, G.R., & Hillyard, S.A, (1991). Modulations of sensory-evoked brain potentials indicate changes in perceptual processing during visual-spatial priming. Journal of Experimental Psychology: Human perception and performance, 17(4): 1057-1074. Although, the visual N1 is widely distributed over the entire scalp, it peaks e ...
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P200
In neuroscience, the visual P200 or P2 is a waveform component or feature of the event-related potential (ERP) measured at the human scalp. Like other potential changes measurable from the scalp, this effect is believed to reflect the post-synaptic activity of a specific neural process. The P2 component, also known as the P200, is so named because it is a positive going electrical potential that peaks at about 200 milliseconds (varying between about 150 and 275 ms) after the onset of some external stimulus. This component is often distributed around the centro-frontal and the parieto-occipital areas of the scalp. It is generally found to be maximal around the vertex (frontal region) of the scalp, however there have been some topographical differences noted in ERP studies of the P2 in different experimental conditions. Research on the visual P2 is at an early stage compared to other more established ERP components and there is much that we still do not know about it. Part of the dif ...
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Evoked Potential
An evoked potential or evoked response is an electrical potential in a specific pattern recorded from a specific part of the nervous system, especially the brain, of a human or other animals following presentation of a stimulus such as a light flash or a pure tone. Different types of potentials result from stimuli of different modalities and types. Evoked potential is distinct from spontaneous potentials as detected by electroencephalography (EEG), electromyography (EMG), or other electrophysiologic recording method. Such potentials are useful for electrodiagnosis and monitoring that include detections of disease and drug-related sensory dysfunction and intraoperative monitoring of sensory pathway integrity. Evoked potential amplitudes tend to be low, ranging from less than a microvolt to several microvolts, compared to tens of microvolts for EEG, millivolts for EMG, and often close to 20 millivolts for ECG. To resolve these low-amplitude potentials against the background ...
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Electrodes
An electrode is an electrical conductor used to make contact with a nonmetallic part of a circuit (e.g. a semiconductor, an electrolyte, a vacuum or air). Electrodes are essential parts of batteries that can consist of a variety of materials depending on the type of battery. The electrophore, invented by Johan Wilcke, was an early version of an electrode used to study static electricity. Anode and cathode in electrochemical cells Electrodes are an essential part of any battery. The first electrochemical battery made was devised by Alessandro Volta and was aptly named the Voltaic cell. This battery consisted of a stack of copper and zinc electrodes separated by brine-soaked paper disks. Due to fluctuation in the voltage provided by the voltaic cell it wasn't very practical. The first practical battery was invented in 1839 and named the Daniell cell after John Frederic Daniell. Still making use of the zinc–copper electrode combination. Since then many more batteries have b ...
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Attention
Attention is the behavioral and cognitive process of selectively concentrating on a discrete aspect of information, whether considered subjective or objective, while ignoring other perceivable information. William James (1890) wrote that "Attention is the taking possession by the mind, in clear and vivid form, of one out of what seem several simultaneously possible objects or trains of thought. Focalization, concentration, of consciousness are of its essence." Attention has also been described as the allocation of limited cognitive processing resources. Attention is manifested by an attentional bottleneck, in terms of the amount of data the brain can process each second; for example, in human vision, only less than 1% of the visual input data (at around one megabyte per second) can enter the bottleneck, leading to inattentional blindness. Attention remains a crucial area of investigation within education, psychology, neuroscience, cognitive neuroscience, and neuropsycho ...
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Superior Temporal Gyrus
The superior temporal gyrus (STG) is one of three (sometimes two) gyri in the temporal lobe of the human brain, which is located laterally to the head, situated somewhat above the external ear. The superior temporal gyrus is bounded by: * the lateral sulcus above; * the superior temporal sulcus (not always present or visible) below; * an imaginary line drawn from the preoccipital notch to the lateral sulcus posteriorly. The superior temporal gyrus contains several important structures of the brain, including: * Brodmann areas 41 and 42, marking the location of the auditory cortex, the cortical region responsible for the sensation of sound; * Wernicke's area, Brodmann 22p, an important region for the processing of speech so that it can be understood as language. The superior temporal gyrus contains the auditory cortex, which is responsible for processing sounds. Specific sound frequencies map precisely onto the auditory cortex. This auditory (or tonotopic) map is similar ...
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Tonotopy
In physiology, tonotopy (from Greek tono = frequency and topos = place) is the spatial arrangement of where sounds of different frequency are processed in the brain. Tones close to each other in terms of frequency are represented in topologically neighbouring regions in the brain. Tonotopic maps are a particular case of topographic organization, similar to retinotopy in the visual system. Tonotopy in the auditory system begins at the cochlea, the small snail-like structure in the inner ear that sends information about sound to the brain. Different regions of the basilar membrane in the organ of Corti, the sound-sensitive portion of the cochlea, vibrate at different sinusoidal frequencies due to variations in thickness and width along the length of the membrane. Nerves that transmit information from different regions of the basilar membrane therefore encode frequency tonotopically. This tonotopy then projects through the vestibulocochlear nerve and associated midbrain structures ...
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Auditory Cortex
The auditory cortex is the part of the temporal lobe that processes auditory information in humans and many other vertebrates. It is a part of the auditory system, performing basic and higher functions in hearing, such as possible relations to language switching.Cf. Pickles, James O. (2012). ''An Introduction to the Physiology of Hearing'' (4th ed.). Bingley, UK: Emerald Group Publishing Limited, p. 238. It is located bilaterally, roughly at the upper sides of the temporal lobes – in humans, curving down and onto the medial surface, on the superior temporal plane, within the lateral sulcus and comprising parts of the transverse temporal gyri, and the superior temporal gyrus, including the planum polare and planum temporale (roughly Brodmann areas 41 and 42, and partially 22). The auditory cortex takes part in the spectrotemporal, meaning involving time and frequency, analysis of the inputs passed on from the ear. The cortex then filters and passes on the information to ...
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Heschl's Gyrus
The transverse temporal gyri, also called Heschl's gyri () or Heschl's convolutions, are gyri found in the area of primary auditory cortex buried within the lateral sulcus of the human brain, occupying Brodmann areas 41 and 42. Transverse temporal gyri are superior to and separated from the planum temporale (cortex involved in language production) by Heschl's sulcus. Transverse temporal gyri are found in varying numbers in both the right and left hemispheres of the brain and one study found that this number is not related to the hemisphere or dominance of hemisphere studied in subjects. Transverse temporal gyri can be viewed in the sagittal plane as either an omega shape (if one gyrus is present) or a heart shape (if two gyri and a sulcus are present). Transverse temporal gyri are the first cortical structures to process incoming auditory information. Anatomically, the transverse temporal gyri are distinct in that they run mediolaterally (toward the center of the brain), rathe ...
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Magnetoencephalography
Magnetoencephalography (MEG) is a functional neuroimaging technique for mapping brain activity by recording magnetic fields produced by electrical currents occurring naturally in the brain, using very sensitive magnetometers. Arrays of SQUIDs (superconducting quantum interference devices) are currently the most common magnetometer, while the SERF (spin exchange relaxation-free) magnetometer is being investigated for future machines. Applications of MEG include basic research into perceptual and cognitive brain processes, localizing regions affected by pathology before surgical removal, determining the function of various parts of the brain, and neurofeedback. This can be applied in a clinical setting to find locations of abnormalities as well as in an experimental setting to simply measure brain activity. History MEG signals were first measured by University of Illinois physicist David Cohen in 1968, before the availability of the SQUID, using a copper induction coil as the ...
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Frequency
Frequency is the number of occurrences of a repeating event per unit of time. It is also occasionally referred to as ''temporal frequency'' for clarity, and is distinct from ''angular frequency''. Frequency is measured in hertz (Hz) which is equal to one event per second. The period is the interval of time between events, so the period is the reciprocal of the frequency. For example, if a heart beats at a frequency of 120 times a minute (2 hertz), the period, —the interval at which the beats repeat—is half a second (60 seconds divided by 120 beats). Frequency is an important parameter used in science and engineering to specify the rate of oscillatory and vibratory phenomena, such as mechanical vibrations, audio signals (sound), radio waves, and light. Definitions and units For cyclical phenomena such as oscillations, waves, or for examples of simple harmonic motion, the term ''frequency'' is defined as the number of cycles or vibrations per unit of time. The ...
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Interstimulus Interval
The interstimulus interval (often abbreviated as ISI) is the temporal interval between the offset of one stimulus to the onset of another. For instance, Max Wertheimer did experiments with two stationary, flashing lights that at some interstimulus intervals appeared to the subject as moving instead of stationary. In these experiments, the interstimulus interval is simply the time between the two flashes. The ISI plays a large role in the phi phenomenon (Wertheimer) since the illusion of motion is directly due to the length of the interval between stimuli. When the ISI is shorter, for example between two flashing lines alternating back and forth, we perceive the change in stimuli to be movement. Wertheimer discovered that the space between the two lines is filled in by our brains and that the faster the lines alternate, the more likely we are to perceive it as one line moving back and forth. When the stimuli move fast enough, this creates the illusion of a moving picture like a movie ...
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