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Nursa Latif Qureshi
The Nuclear Receptor Signaling Atlas (NURSA) was a United States National Institutes of Health-funded research consortium focused on nuclear receptors and nuclear receptor coregulators. Its co-principal investigators were Bert O'Malley and Neil McKenna of Baylor College of Medicine and Ron Evans Ronald Barry Evans AM (7 July 1939 – 9 March 2007) was an Australian rules footballer, Chairman of the Australian Football League (AFL) from 1998 to 2007, as well as President of the Essendon Football Club from 1988 to 1992. Education E ... of the Salk Institute. NURSA has now been retired and replaced by the Signaling Pathways Project (SPP). References External links * Biological databases {{bioinformatics-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Institutes Of Health
The National Institutes of Health, commonly referred to as NIH (with each letter pronounced individually), is the primary agency of the United States government responsible for biomedical and public health research. It was founded in the late 1880s and is now part of the United States Department of Health and Human Services. The majority of NIH facilities are located in Bethesda, Maryland, and other nearby suburbs of the Washington metropolitan area, with other primary facilities in the Research Triangle Park in North Carolina and smaller satellite facilities located around the United States. The NIH conducts its own scientific research through the NIH Intramural Research Program (IRP) and provides major biomedical research funding to non-NIH research facilities through its Extramural Research Program. , the IRP had 1,200 principal investigators and more than 4,000 postdoctoral fellows in basic, translational, and clinical research, being the largest biomedical research instit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nuclear Receptors
In the field of molecular biology, nuclear receptors are a class of proteins responsible for sensing steroids, thyroid hormones, vitamins, and certain other molecules. These receptors work with other proteins to regulate the expression of specific genes thereby controlling the development, homeostasis, and metabolism of the organism. Nuclear receptors bind directly to DNA regulating the expression of adjacent genes; hence these receptors are classified as transcription factors. The regulation of gene expression by nuclear receptors often occurs in the presence of a ligand—a molecule that affects the receptor's behavior. Ligand binding to a nuclear receptor results in a conformational change activating the receptor. The result is up- or down-regulation of gene expression. A unique property of nuclear receptors that differentiates them from other classes of receptors is their direct control of genomic DNA. Nuclear receptors play key roles in both embryonic development and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Transcription Coregulator
In molecular biology and genetics, transcription coregulators are proteins that interact with transcription factors to either activate or repress the transcription of specific genes. Transcription coregulators that activate gene transcription are referred to as coactivators while those that repress are known as corepressors. The mechanism of action of transcription coregulators is to modify chromatin structure and thereby make the associated DNA more or less accessible to transcription. In humans several dozen to several hundred coregulators are known, depending on the level of confidence with which the characterisation of a protein as a coregulator can be made. One class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP dependent class modifies the conformation of chromatin. Histone acetyltransferases Nuclear DNA is normally tightly wrapped around histones rendering the DNA inaccessible to the general transc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bert W
Bert or BERT may refer to: Persons, characters, or animals known as Bert *Bert (name), commonly an abbreviated forename and sometimes a surname *Bert, a character in the poem "Bert the Wombat" by The Wiggles; from their 1992 album Here Comes a Song *Bert (Sesame Street), fictional character on the TV series ''Sesame Street'' *Bert (horse), foaled 1934 *Bert (Mary Poppins), a Cockney chimney sweep in the book series & Disney film ''Mary Poppins'' * Iron Bert (one half of the two yellow diesels 'Arry and Bert), also in ''Thomas and Friends'' Places *Berd, Armenia, also known as Bert *Bert, Allier, a commune in the French of Allier *Bert, West Virginia Electronics & computing *Bit error rate test, a testing method for digital communication circuits *Bit error rate tester, a test equipment used for testing the bit error rate of digital communication circuits *HP Bert, a CPU in certain Hewlett-Packard programmable calculators *BERT (language model) (Bidirectional Encoder Representatio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ronald M
Ronald is a masculine given name derived from the Old Norse ''Rögnvaldr'', Hanks; Hardcastle; Hodges (2006) p. 234; Hanks; Hodges (2003) § Ronald. or possibly from Old English '' Regenweald''. In some cases ''Ronald'' is an Anglicised form of the Gaelic ''Raghnall'', a name likewise derived from ''Rögnvaldr''. The latter name is composed of the Old Norse elements ''regin'' ("advice", "decision") and ''valdr'' ("ruler"). ''Ronald'' was originally used in England and Scotland, where Scandinavian influences were once substantial, although now the name is common throughout the English-speaking world. A short form of ''Ronald'' is ''Ron''. Pet forms of ''Ronald'' include ''Roni'' and ''Ronnie''. ''Ronalda'' and ''Rhonda'' are feminine forms of ''Ronald''. '' Rhona'', a modern name apparently only dating back to the late nineteenth century, may have originated as a feminine form of ''Ronald''. Hanks; Hardcastle; Hodges (2006) pp. 230, 408; Hanks; Hodges (2003) § Rhona. The names ' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
