Nocardia Brasiliensis
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Nocardia Brasiliensis
''Nocardia brasiliensis'' is a species of ''Nocardia''. As with most members of Actinomycetota, they contain high guanine and cytosine content. It can cause nocardiosis Nocardiosis is an infectious disease affecting either the lungs (''pulmonary nocardiosis'') or the whole body (''systemic nocardiosis''). It is due to infection by a bacterium of the genus ''Nocardia'', most commonly ''Nocardia asteroides'' or '' N .... References Further reading * External linksType strain of ''Nocardia brasiliensis'' at Bac''Dive'' - the Bacterial Diversity Metadatabase Mycobacteriales Bacteria described in 1913 {{actinobacteria-stub ...
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Nippostrongylus Brasiliensis
''Nippostrongylus brasiliensis'' is a gastrointestinal roundworm that infects rodents, primarily rats. This worm is a widely studied parasite due to its simple lifecycle and its ability to be used in animal models. Its lifecycle similar to the human hookworms ''Necator americanus'' and ''Ancylostoma duodenale'' which includes five molting stages to become sexually mature. Lifecycle Eggs located within the soil release motile, free-living worms that must moult twice (L1 and L2) to develop into their infective L3 stage. This L3 stage can penetrate through intact skin in as little as 4 hours. Once inside the host, the worms invade the venous circulation and are carried into the lungs, where they become trapped in the capillaries. When the worms mature into the L4 stage, they rupture the capillaries and are released into the alveoli, where they are coughed up and swallowed. They then reach the small intestines 3–4 days after the initial infection. The worms become adults after the ...
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Nocardia
''Nocardia'' is a genus of weakly staining Gram-positive, catalase-positive, rod-shaped bacteria. It forms partially acid-fast beaded branching filaments (acting as fungi, but being truly bacteria). It contains a total of 85 species. Some species are nonpathogenic, while others are responsible for nocardiosis. ''Nocardia'' species are found worldwide in soil rich in organic matter. In addition, they are oral microflora found in healthy gingiva, as well as periodontal pockets. Most ''Nocardia'' infections are acquired by inhalation of the bacteria or through traumatic introduction. Culture and staining ''Nocardia'' colonies have a variable appearance, but most species appear to have aerial hyphae when viewed with a dissecting microscope, particularly when they have been grown on nutritionally limiting media. ''Nocardia'' grow slowly on nonselective culture media, and are strict aerobes with the ability to grow in a wide temperature range. Some species are partially acid-fast ...
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Actinomycetota
The ''Actinomycetota'' (or ''Actinobacteria'') are a phylum of all gram-positive bacteria. They can be terrestrial or aquatic. They are of great economic importance to humans because agriculture and forests depend on their contributions to soil systems. In soil they help to decompose the organic matter of dead organisms so the molecules can be taken up anew by plants. While this role is also played by fungi, ''Actinomycetota'' are much smaller and likely do not occupy the same ecological niche. In this role the colonies often grow extensive mycelia, like a fungus would, and the name of an important order of the phylum, '' Actinomycetales'' (the actinomycetes), reflects that they were long believed to be fungi. Some soil actinomycetota (such as ''Frankia'') live symbiotically with the plants whose roots pervade the soil, fixing nitrogen for the plants in exchange for access to some of the plant's saccharides. Other species, such as many members of the genus '' Mycobacterium'', ar ...
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Guanine
Guanine () ( symbol G or Gua) is one of the four main nucleobases found in the nucleic acids DNA and RNA, the others being adenine, cytosine, and thymine (uracil in RNA). In DNA, guanine is paired with cytosine. The guanine nucleoside is called guanosine. With the formula C5H5N5O, guanine is a derivative of purine, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds. This unsaturated arrangement means the bicyclic molecule is planar. Properties Guanine, along with adenine and cytosine, is present in both DNA and RNA, whereas thymine is usually seen only in DNA, and uracil only in RNA. Guanine has two tautomeric forms, the major keto form (see figures) and rare enol form. It binds to cytosine through three hydrogen bonds. In cytosine, the amino group acts as the hydrogen bond donor and the C-2 carbonyl and the N-3 amine as the hydrogen-bond acceptors. Guanine has the C-6 carbonyl group that acts as the hydrogen bond acceptor, while a group at N ...
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Cytosine
Cytosine () ( symbol C or Cyt) is one of the four nucleobases found in DNA and RNA, along with adenine, guanine, and thymine (uracil in RNA). It is a pyrimidine derivative, with a heterocyclic aromatic ring and two substituents attached (an amine group at position 4 and a keto group at position 2). The nucleoside of cytosine is cytidine. In Watson-Crick base pairing, it forms three hydrogen bonds with guanine. History Cytosine was discovered and named by Albrecht Kossel and Albert Neumann in 1894 when it was hydrolyzed from calf thymus tissues. A structure was proposed in 1903, and was synthesized (and thus confirmed) in the laboratory in the same year. In 1998, cytosine was used in an early demonstration of quantum information processing when Oxford University researchers implemented the Deutsch-Jozsa algorithm on a two qubit nuclear magnetic resonance quantum computer (NMRQC). In March 2015, NASA scientists reported the formation of cytosine, along with uracil and thym ...
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Nocardiosis
Nocardiosis is an infectious disease affecting either the lungs (''pulmonary nocardiosis'') or the whole body (''systemic nocardiosis''). It is due to infection by a bacterium of the genus ''Nocardia'', most commonly ''Nocardia asteroides'' or '' Nocardia brasiliensis''. It is most common in adult males, especially those with a weakened immune system. In patients with brain nocardia infection, mortality exceeds 80%; in other forms, mortality is 50%, even with appropriate therapy. It is one of several conditions that have been called "the great imitator". Cutaneous nocardiosis commonly occurs in immunocompetent hosts and is caused in 80% of cases by ''Nocardia brasiliensis''. Signs and symptoms Pulmonary infection * Produces a virulent form of pneumonia (progressive) * Night sweats, fever, cough, chest pain * Pulmonary nocardiosis is subacute in onset and refractory to treatment with standard antibiotics * Symptoms are more severe in immunocompromised individuals * Radiologic studi ...
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Mycobacteriales
The Mycobacteriales are an order of bacteria. Phylogeny The currently accepted taxonomy is based on the List of Prokaryotic names with Standing in Nomenclature List of Prokaryotic names with Standing in Nomenclature (LPSN) is an online database that maintains information on the naming and taxonomy of prokaryotes, following the taxonomy requirements and rulings of the International Code of Nomenclature ... (LPSN). The phylogeny is based on whole-genome analysis. References Actinomycetia Bacteria orders {{actinobacteria-stub ...
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