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Nitrogen-13
Nitrogen-13 (13N) is a radioisotope of nitrogen used in positron emission tomography (PET). It has a half-life of a little under ten minutes, so it must be made at the PET site. A cyclotron may be used for this purpose. Nitrogen-13 is used to tag ammonia molecules for PET myocardial perfusion imaging. Production Nitrogen-13 is used in medical PET imaging in the form of 13N-labelled ammonia. It can be produced with a medical cyclotron, using a target of pure water with a trace amount of ethanol. The reactants are oxygen-16 (present as H2O) and a proton, and the products are nitrogen-13 and an alpha particle (helium-4). :1H + 16O → 13N + 4He The proton must be accelerated to have total energy greater than 5.66 MeV. This is the threshold energy for this reaction, as it is endothermic (i.e., the mass of the products is greater than the reactants, so energy needs to be supplied which is converted to mass). For this reason, the proton needs to carry extra energy to induce the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oxygen-13
There are three known stable isotopes of oxygen (8O): , , and . Radioactive isotopes ranging from to have also been characterized, all short-lived. The longest-lived radioisotope is with a half-life of , while the shortest-lived isotope is with a half-life of (though the half-lives of the neutron-unbound and are still unknown). List of isotopes , - , , style="text-align:right" , 8 , style="text-align:right" , 3 , , [] , proton emission, 2p , , (3/2−) , , , - , , style="text-align:right" , 8 , style="text-align:right" , 4 , , , 2p , , 0+ , , , - , rowspan=2, , rowspan=2 style="text-align:right" , 8 , rowspan=2 style="text-align:right" , 5 , rowspan=2, , rowspan=2, , β+ () , , rowspan=2, (3/2−) , rowspan=2, , rowspan=2, , - , β+p () , , - , , style="text-align:right" , 8 , style="text-align:right" , 6 , , , β+ , , 0+ , , , - , , style="text-align:right" , 8 , style="text-align:right" , 7 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Isotopes Of Nitrogen
Natural nitrogen (7N) consists of two stable isotopes: the vast majority (99.6%) of naturally occurring nitrogen is nitrogen-14, with the remainder being nitrogen-15. Fourteen radioisotopes are also known, with atomic masses ranging from 10 to 25, along with one nuclear isomer, 11mN. All of these radioisotopes are short-lived, the longest-lived being nitrogen-13 with a half-life of . All of the others have half-lives below 7.15 seconds, with most of these being below 620 milliseconds. Most of the isotopes with atomic mass numbers below 14 decay to isotopes of carbon, while most of the isotopes with masses above 15 decay to isotopes of oxygen. The shortest-lived known isotope is nitrogen-10, with a half-life of . List of isotopes , - , , style="text-align:right" , 7 , style="text-align:right" , 3 , , , p ?Decay mode shown is energetically allowed, but has not been experimentally observed to occur in this nuclide. , ? , 1−, 2− , , , - , , style="text-align:r ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nitrogen-14
Natural nitrogen (7N) consists of two stable isotopes: the vast majority (99.6%) of naturally occurring nitrogen is nitrogen-14, with the remainder being nitrogen-15. Fourteen radioisotopes are also known, with atomic masses ranging from 10 to 25, along with one nuclear isomer, 11mN. All of these radioisotopes are short-lived, the longest-lived being nitrogen-13 with a half-life of . All of the others have half-lives below 7.15 seconds, with most of these being below 620 milliseconds. Most of the isotopes with atomic mass numbers below 14 decay to isotopes of carbon, while most of the isotopes with masses above 15 decay to isotopes of oxygen. The shortest-lived known isotope is nitrogen-10, with a half-life of . List of isotopes , - , , style="text-align:right" , 7 , style="text-align:right" , 3 , , , p ?Decay mode shown is energetically allowed, but has not been experimentally observed to occur in this nuclide. , ? , 1−, 2− , , , - , , style="text-align:r ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nitrogen-12
Natural nitrogen (7N) consists of two stable isotopes: the vast majority (99.6%) of naturally occurring nitrogen is nitrogen-14, with the remainder being nitrogen-15. Fourteen radioisotopes are also known, with atomic masses ranging from 10 to 25, along with one nuclear isomer, 11mN. All of these radioisotopes are short-lived, the longest-lived being nitrogen-13 with a half-life of . All of the others have half-lives below 7.15 seconds, with most of these being below 620 milliseconds. Most of the isotopes with atomic mass numbers below 14 decay to isotopes of carbon, while most of the isotopes with masses above 15 decay to isotopes of oxygen. The shortest-lived known isotope is nitrogen-10, with a half-life of . List of isotopes , - , , style="text-align:right" , 7 , style="text-align:right" , 3 , , , p ?Decay mode shown is energetically allowed, but has not been experimentally observed to occur in this nuclide. , ? , 1−, 2− , , , - , , style="text-align:r ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Myocardial Perfusion Imaging
Myocardial perfusion imaging or scanning (also referred to as MPI or MPS) is a nuclear medicine procedure that illustrates the function of the heart muscle (myocardium). It evaluates many heart conditions, such as coronary artery disease (CAD), hypertrophic cardiomyopathy and heart wall motion abnormalities. It can also detect regions of myocardial infarction by showing areas of decreased resting perfusion. The function of the myocardium is also evaluated by calculating the left ventricular ejection fraction (LVEF) of the heart. This scan is done in conjunction with a cardiac stress test. The diagnostic information is generated by provoking controlled regional ischemia in the heart with variable perfusion. Planar techniques, such as conventional scintigraphy, are rarely used. Rather, single-photon emission computed tomography (SPECT) is more common in the US. With multihead SPECT systems, imaging can often be completed in less than 10 minutes. With SPECT, inferior and posterior a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Carbon-13
Carbon-13 (13C) is a natural, stable isotope of carbon with a nucleus containing six protons and seven neutrons. As one of the environmental isotopes, it makes up about 1.1% of all natural carbon on Earth. Detection by mass spectrometry A mass spectrum of an organic compound will usually contain a small peak of one mass unit greater than the apparent molecular ion peak (M) of the whole molecule. This is known as the M+1 peak and comes from the few molecules that contain a 13C atom in place of a 12C. A molecule containing one carbon atom will be expected to have an M+1 peak of approximately 1.1% of the size of the M peak, as 1.1% of the molecules will have a 13C rather than a 12C. Similarly, a molecule containing two carbon atoms will be expected to have an M+1 peak of approximately 2.2% of the size of the M peak, as there is double the previous likelihood that any molecule will contain a 13C atom. In the above, the mathematics and chemistry have been simplified, however it can ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
CNO Cycle
The CNO cycle (for carbon–nitrogen–oxygen; sometimes called Bethe–Weizsäcker cycle after Hans Albrecht Bethe and Carl Friedrich von Weizsäcker) is one of the two known sets of fusion reactions by which stars convert hydrogen to helium, the other being the proton–proton chain reaction (p–p cycle), which is more efficient at the Sun's core temperature. The CNO cycle is hypothesized to be dominant in stars that are more than 1.3 times as massive as the Sun. Unlike the proton-proton reaction, which consumes all its constituents, the CNO cycle is a catalytic cycle. In the CNO cycle, four protons fuse, using carbon, nitrogen, and oxygen isotopes as catalysts, each of which is consumed at one step of the CNO cycle, but re-generated in a later step. The end product is one alpha particle (a stable helium nucleus), two positrons, and two electron neutrinos. There are various alternative paths and catalysts involved in the CNO cycles, all these cycles have the same ne ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
CNO Cycle
The CNO cycle (for carbon–nitrogen–oxygen; sometimes called Bethe–Weizsäcker cycle after Hans Albrecht Bethe and Carl Friedrich von Weizsäcker) is one of the two known sets of fusion reactions by which stars convert hydrogen to helium, the other being the proton–proton chain reaction (p–p cycle), which is more efficient at the Sun's core temperature. The CNO cycle is hypothesized to be dominant in stars that are more than 1.3 times as massive as the Sun. Unlike the proton-proton reaction, which consumes all its constituents, the CNO cycle is a catalytic cycle. In the CNO cycle, four protons fuse, using carbon, nitrogen, and oxygen isotopes as catalysts, each of which is consumed at one step of the CNO cycle, but re-generated in a later step. The end product is one alpha particle (a stable helium nucleus), two positrons, and two electron neutrinos. There are various alternative paths and catalysts involved in the CNO cycles, all these cycles have the same ne ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Carbon-13
Carbon-13 (13C) is a natural, stable isotope of carbon with a nucleus containing six protons and seven neutrons. As one of the environmental isotopes, it makes up about 1.1% of all natural carbon on Earth. Detection by mass spectrometry A mass spectrum of an organic compound will usually contain a small peak of one mass unit greater than the apparent molecular ion peak (M) of the whole molecule. This is known as the M+1 peak and comes from the few molecules that contain a 13C atom in place of a 12C. A molecule containing one carbon atom will be expected to have an M+1 peak of approximately 1.1% of the size of the M peak, as 1.1% of the molecules will have a 13C rather than a 12C. Similarly, a molecule containing two carbon atoms will be expected to have an M+1 peak of approximately 2.2% of the size of the M peak, as there is double the previous likelihood that any molecule will contain a 13C atom. In the above, the mathematics and chemistry have been simplified, however it can ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Positron Emission
Positron emission, beta plus decay, or β+ decay is a subtype of radioactive decay called beta decay, in which a proton inside a radionuclide nucleus is converted into a neutron while releasing a positron and an electron neutrino (). Positron emission is mediated by the weak force. The positron is a type of beta particle (β+), the other beta particle being the electron (β−) emitted from the β− decay of a nucleus. An example of positron emission (β+ decay) is shown with magnesium-23 decaying into sodium-23: : → + + Because positron emission decreases proton number relative to neutron number, positron decay happens typically in large "proton-rich" radionuclides. Positron decay results in nuclear transmutation, changing an atom of one chemical element into an atom of an element with an atomic number that is less by one unit. Positron emission occurs only very rarely naturally on earth, when induced by a cosmic ray or from one in a hundred thousand decays of pot ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nitrogen
Nitrogen is the chemical element with the symbol N and atomic number 7. Nitrogen is a nonmetal and the lightest member of group 15 of the periodic table, often called the pnictogens. It is a common element in the universe, estimated at seventh in total abundance in the Milky Way and the Solar System. At standard temperature and pressure, two atoms of the element bond to form N2, a colorless and odorless diatomic gas. N2 forms about 78% of Earth's atmosphere, making it the most abundant uncombined element. Nitrogen occurs in all organisms, primarily in amino acids (and thus proteins), in the nucleic acids ( DNA and RNA) and in the energy transfer molecule adenosine triphosphate. The human body contains about 3% nitrogen by mass, the fourth most abundant element in the body after oxygen, carbon, and hydrogen. The nitrogen cycle describes the movement of the element from the air, into the biosphere and organic compounds, then back into the atmosphere. Many indus ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Positron Emission Tomography
Positron emission tomography (PET) is a functional imaging technique that uses radioactive substances known as radiotracers to visualize and measure changes in Metabolism, metabolic processes, and in other physiological activities including blood flow, regional chemical composition, and absorption. Different tracers are used for various imaging purposes, depending on the target process within the body. For example, 18F-FDG, -FDG is commonly used to detect cancer, Sodium fluoride#Medical imaging, NaF is widely used for detecting bone formation, and Isotopes of oxygen#Oxygen-15, oxygen-15 is sometimes used to measure blood flow. PET is a common medical imaging, imaging technique, a Scintigraphy#Process, medical scintillography technique used in nuclear medicine. A radiopharmaceutical, radiopharmaceutical — a radioisotope attached to a drug — is injected into the body as a radioactive tracer, tracer. When the radiopharmaceutical undergoes beta plus decay, a positron is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
