Neurobiological Technologies
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Neurobiological Technologies
Neurobiological Technologies, Inc. ("NTI") was a biotechnology company that was founded in 1987 by Enoch Callaway and John B. Stuppin to in-license and develop drugs primarily to treat neurological conditions; the company was dissolved in 2009 after the failure of its drug candidate ancrod in a Phase III trial for ischemic stroke. NTI-Children's license is included in the filing. The company pursued a virtual company model from the beginning, keeping staff as small as possible and outsourcing tasks to contract research organizations and contract manufacturing organizations. At the time the company made its first public offering in 1996, it had three products in development: memantine, a small molecule for neuropathic pain and AIDS-related dementia, corticotropin-releasing factor, a biopharmaceutical to treat edema caused by brain tumors and inflammation caused by rheumatoid arthritis, and dynorphin A, a biopharmaceutical to treat pain. It licensed patents covering methods to use m ...
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Enoch Callaway
Enoch "Noch" Callaway III (July 12, 1924 – August 18, 2014) was an American psychiatrist and a pioneer in biological psychiatry. Biography Callaway was born on July 12, 1924, into an old southern family of doctors in La Grange, Georgia. He is a descendant of the family that founded the Callaway Plantation in Washington, Georgia and Callaway Gardens in Pine Mountain, Georgia. Members of his extended family also include Ely Callaway Jr., founder of Callaway Golf Company, textile manufacturer Fuller Earle Callaway, and former United States Secretary of the Army and Georgia Congressman Bo Callaway. He graduated from Columbia University in 1944 and obtained his M.D. from Columbia College of Physicians and Surgeons in 1947. He completed his residency at Worcester State Hospital in Massachusetts and pursued advanced study at Johns Hopkins University. In 1959, Callaway was appointed director of research of the Langley Porter Psychiatric Institute in San Francisco and continued i ...
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Merz Pharma
Merz Pharma GmbH & Co. KGaA is a privately-held pharmaceutical company based in Frankfurt, Germany with affiliates across Europe, as well as the US, Canada, Mexico, Brazil and Asia Pacific and regional headquarters in Singapore and North Carolina, USA. The company is active in research, development and distribution of products in the areas of aesthetic medicine and neurologically induced movement disorders. In German-speaking countries, the Merz consumer products business, Merz Consumer Care, is a provider of health, wellness and beauty products with its tetesept and Merz Spezial brands. Today, Merz’s global businesses are focused on the areas of medical aesthetics and neurotoxin therapy, supported by regional brands in both the prescription medicine and consumer health and beauty sectors. Key brands in the Merz Aesthetics portfolio include Belotero, Radiesse, Cellfina, Ultherapy, certain brands of Botulinum Toxin Botulinum toxin, or botulinum neurotoxin (BoNT), is a ne ...
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1987 Establishments In California
File:1987 Events Collage.png, From top left, clockwise: The MS Herald of Free Enterprise capsizes after leaving the Port of Zeebrugge in Belgium, killing 193; Northwest Airlines Flight 255 crashes after takeoff from Detroit Metropolitan Airport, killing everyone except a little girl; The King's Cross fire kills 31 people after a fire under an escalator flashes-over; The MV Doña Paz sinks after colliding with an oil tanker, drowning almost 4,400 passengers and crew; Typhoon Nina strikes the Philippines; LOT Polish Airlines Flight 5055 crashes outside of Warsaw, taking the lives of all aboard; The USS Stark is struck by Iraqi Exocet missiles in the Persian Gulf; U.S. President Ronald Reagan gives a famous speech, demanding that Soviet leader Mikhail Gorbachev tears down the Berlin Wall., 300x300px, thumb rect 0 0 200 200 Zeebrugge disaster rect 200 0 400 200 Northwest Airlines Flight 255 rect 400 0 600 200 King's Cross fire rect 0 200 300 400 Tear down this wall! rect 300 ...
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Biotechnology Companies Disestablished In 2009
Biotechnology is the integration of natural sciences and engineering sciences in order to achieve the application of organisms, cells, parts thereof and molecular analogues for products and services. The term ''biotechnology'' was first used by Károly Ereky in 1919, meaning the production of products from raw materials with the aid of living organisms. Definition The concept of biotechnology encompasses a wide range of procedures for modifying living organisms according to human purposes, going back to domestication of animals, cultivation of the plants, and "improvements" to these through breeding programs that employ artificial selection and hybridization. Modern usage also includes genetic engineering as well as cell and tissue culture technologies. The American Chemical Society defines biotechnology as the application of biological organisms, systems, or processes by various industries to learning about the science of life and the improvement of the value of materials ...
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Biotechnology Companies Established In 1987
Biotechnology is the integration of natural sciences and engineering sciences in order to achieve the application of organisms, cells, parts thereof and molecular analogues for products and services. The term ''biotechnology'' was first used by Károly Ereky in 1919, meaning the production of products from raw materials with the aid of living organisms. Definition The concept of biotechnology encompasses a wide range of procedures for modifying living organisms according to human purposes, going back to domestication of animals, cultivation of the plants, and "improvements" to these through breeding programs that employ artificial selection and hybridization. Modern usage also includes genetic engineering as well as cell and tissue culture technologies. The American Chemical Society defines biotechnology as the application of biological organisms, systems, or processes by various industries to learning about the science of life and the improvement of the value of materials a ...
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Defunct Companies Based In The San Francisco Bay Area
Defunct (no longer in use or active) may refer to: * ''Defunct'' (video game), 2014 * Zombie process or defunct process, in Unix-like operating systems See also * * :Former entities * End-of-life product * Obsolescence Obsolescence is the state of being which occurs when an object, service, or practice is no longer maintained or required even though it may still be in good working order. It usually happens when something that is more efficient or less risky r ...
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Chiron Corporation
Chiron Corporation ( ) was an American multinational biotechnology firm founded in 1981, based in Emeryville, California, that was acquired by Novartis on April 20, 2006. It had offices and facilities in eighteen countries on five continents. Chiron's business and research was in three main areas: biopharmaceuticals, vaccines, and blood testing. Chiron's vaccines and blood testing units were combined to form Novartis Vaccines and Diagnostics, while Chiron BioPharmaceuticals was integrated into Novartis Pharmaceuticals. In 2014, Novartis completed the sale of its blood transfusion diagnostics unit to Grifols and announced agreements for the sale of its vaccines unit to GlaxoSmithKline. Early history Chiron was founded in 1981 by chairman, William J. Rutter, president and chief executive, Professor Edward Penhoet, and vice president for research, Pablo DT Valenzuela. All were academics from the University of California; Penhoet at Berkeley, where he continued to lecture, and ...
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Cetus Corporation
Cetus Corporation was one of the first biotechnology companies. It was established in Berkeley, California, in 1971, but conducted most of its operations in nearby Emeryville. Before merging with Chiron Corporation in 1991 (now a part of Novartis), it developed several significant pharmaceutical drugs as well as a revolutionary DNA amplification technique. History Cetus was founded in 1971 by Ronald E. Cape, Peter Farley, and Nobelist Donald A. Glaser. Its early efforts involved automated methods to select for industrial microorganisms that could produce greater amounts of chemical feedstocks, antibiotics, or vaccine components. By the late 1970s, however, three new revolutionary techniques had been developed: recombinant DNA, monoclonal antibodies, and gene expression, the foundations of the biotechnology industry. In order to enter these new fields, Cetus raised $108 million in an initial public offering (IPO) in 1981, the largest IPO to that date. Its first large deve ...
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Abbott Laboratories
Abbott Laboratories is an American multinational medical devices and health care company with headquarters in Abbott Park, Illinois, United States. The company was founded by Chicago physician Wallace Calvin Abbott in 1888 to formulate known drugs; today, it sells medical devices, diagnostics, branded generic medicines and nutritional products. It split off its research-based pharmaceuticals business into AbbVie in 2013. The firm has also been present in India for over 100 years through its subsidiary Abbott India Limited, and it is currently India's largest healthcare products company. Among its well-known products across the medical devices, diagnostics, and nutrition product divisions are Pedialyte, Similac, BinaxNOW, Ensure, Glucerna, ZonePerfect, FreeStyle Libre, i-STAT and MitraClip. History Foundation and early history In 1888 at the age of 30, Wallace Abbott (1857–1921), an 1885 graduate of the University of Michigan, founded the Abbott Alkaloidal Company in ...
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Knoll Pharmaceuticals
Knoll Pharmaceuticals was a drug development company founded by Albert Knoll and Hans Knoll in Germany in 1886. The company was taken over by German BASF in 1975, which sold it to Abbott Laboratories on 30 June 2002 for $6.9 billion. It was the developer of several drugs: Dilaudid (hydromorphone), a powerful and very water-soluble narcotic analgesic (Betäubungsmittel) introduced in 1926, as small oral tablets of a number of strengths, multipurpose (hypodermic) tablets, compounding powder, ampoules of solution for injection, and dry ampoules for reconstitution. Knoll also produced somewhat similar hydrocodone tablets named Dicodid; this drug which compares to codeine as hydromorphone compares to morphine was first synthesised and announced in Germany in 1920. The obverse sides of the oral tablets bear a stylised letter "K" and the reverse has the relevant imprint code for the medication in the locale of sale and/or number of milligrammes of hydromorphone. Sibutramine, a seroto ...
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Forest Laboratories
Forest Laboratories was a company in the pharmaceutical industry incorporated in Delaware, with its principal office in New York City. It was known for licensing European pharmaceuticals for sale in the United States. On July 1, 2014, the company was acquired by Actavis (now Allergan). History The company was founded by Hans Lowey in 1956 as a small laboratory service company. In 1967, the company became a public company via an initial public offering. In 1977, Howard Solomon became the chief executive officer of the company. In 1984, the company acquired O'Neal Jones & Feldman for $8.8 million after a federal investigation resulted in one of its drugs being recalled. On July 17, 1998, the company received approval from the Food and Drug Administration for Celexa (Citalopram), an antidepressant. In 2000, the company cut ties with Warner-Lambert for the marketing of Celexa after Warner-Lambert was acquired by Pfizer. On August 16, 2002, the company received approval from t ...
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Children's Hospital Of Boston
Boston Children's Hospital formerly known as Children's Hospital Boston until 2012 is a nationally ranked, freestanding acute care Pediatrics, children's hospital located in Boston, Massachusetts, adjacent both to its teaching affiliate, Harvard Medical School, and to Dana–Farber Cancer Institute. Dana–Farber and Children's jointly operate the Dana–Farber/Boston Children's Cancer and Blood Disorders Center to deliver comprehensive care for all types of childhood cancers. The hospital is home to the largest hospital-based pediatric research program in the world. The hospital features 485 pediatric beds and provides comprehensive pediatric specialties and subspecialties to infants, children, teens, and young adults aged 0–21 throughout Massachusetts, the United States, and the world. The hospital also sometimes treats adults that require pediatric care. The hospital uses the Brigham and Women's Hospital's rooftop helipad and is an American College of Surgeons, ACS verified L ...
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