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NeuroLex Screen Shot 2014-02-01
NeuroLex is a lexicon of neuroscience concepts. It is a structured as a semantic wiki, using Semantic MediaWiki. NeuroLex is supported by the Neuroscience Information Framework project. Overview The NeuroLex is intended to help improve the way that neuroscientists communicate about their work, so that information systems like the NIF can more easily find and integrate data that occur across distributed resources. One of the big roadblocks to data integration in neuroscience is the inconsistent use of terminology in databases and other literature. For example, if three databases have information about what genes are expressed in cortex, but they all use different definitions of cerebral cortex, then one cannot compare them easily. Utilization within the Neuroscience Information Framework The NIF enables discovery and access to public research data and tools worldwide through an open source, networked environment. Funded by the NIH Blueprint for Neuroscience Research,ThNIH Bl ...
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NeuroLex Screen Shot 2014-02-01
NeuroLex is a lexicon of neuroscience concepts. It is a structured as a semantic wiki, using Semantic MediaWiki. NeuroLex is supported by the Neuroscience Information Framework project. Overview The NeuroLex is intended to help improve the way that neuroscientists communicate about their work, so that information systems like the NIF can more easily find and integrate data that occur across distributed resources. One of the big roadblocks to data integration in neuroscience is the inconsistent use of terminology in databases and other literature. For example, if three databases have information about what genes are expressed in cortex, but they all use different definitions of cerebral cortex, then one cannot compare them easily. Utilization within the Neuroscience Information Framework The NIF enables discovery and access to public research data and tools worldwide through an open source, networked environment. Funded by the NIH Blueprint for Neuroscience Research,ThNIH Bl ...
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National Institutes Of Health
The National Institutes of Health, commonly referred to as NIH (with each letter pronounced individually), is the primary agency of the United States government responsible for biomedical and public health research. It was founded in the late 1880s and is now part of the United States Department of Health and Human Services. The majority of NIH facilities are located in Bethesda, Maryland, and other nearby suburbs of the Washington metropolitan area, with other primary facilities in the Research Triangle Park in North Carolina and smaller satellite facilities located around the United States. The NIH conducts its own scientific research through the NIH Intramural Research Program (IRP) and provides major biomedical research funding to non-NIH research facilities through its Extramural Research Program. , the IRP had 1,200 principal investigators and more than 4,000 postdoctoral fellows in basic, translational, and clinical research, being the largest biomedical research instit ...
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Anatomical Terminology
Anatomical terminology is a form of scientific terminology used by anatomists, zoologists, and health professionals such as doctors. Anatomical terminology uses many unique terms, suffixes, and prefixes deriving from Ancient Greek and Latin. These terms can be confusing to those unfamiliar with them, but can be more precise, reducing ambiguity and errors. Also, since these anatomical terms are not used in everyday conversation, their meanings are less likely to change, and less likely to be misinterpreted. To illustrate how inexact day-to-day language can be: a scar "above the wrist" could be located on the forearm two or three inches away from the hand or at the base of the hand; and could be on the palm-side or back-side of the arm. By using precise anatomical terminology such ambiguity is eliminated. An international standard for anatomical terminology, ''Terminologia Anatomica'' has been created. Word formation Anatomical terminology has quite regular morphology: the same ...
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Ontology (information Science)
In computer science and information science, an ontology encompasses a representation, formal naming, and definition of the categories, properties, and relations between the concepts, data, and entities that substantiate one, many, or all domains of discourse. More simply, an ontology is a way of showing the properties of a subject area and how they are related, by defining a set of concepts and categories that represent the subject. Every academic discipline or field creates ontologies to limit complexity and organize data into information and knowledge. Each uses ontological assumptions to frame explicit theories, research and applications. New ontologies may improve problem solving within that domain. Translating research papers within every field is a problem made easier when experts from different countries maintain a controlled vocabulary of jargon between each of their languages. For instance, the definition and ontology of economics is a primary concern in Marxist econo ...
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Semantic Wikis
Semantics (from grc, σημαντικός ''sēmantikós'', "significant") is the study of reference, meaning, or truth. The term can be used to refer to subfields of several distinct disciplines, including philosophy, linguistics and computer science. History In English, the study of meaning in language has been known by many names that involve the Ancient Greek word (''sema'', "sign, mark, token"). In 1690, a Greek rendering of the term ''semiotics'', the interpretation of signs and symbols, finds an early allusion in John Locke's ''An Essay Concerning Human Understanding'': The third Branch may be called [''simeiotikí'', "semiotics"], or the Doctrine of Signs, the most usual whereof being words, it is aptly enough termed also , Logick. In 1831, the term is suggested for the third branch of division of knowledge akin to Locke; the "signs of our knowledge". In 1857, the term ''semasiology'' (borrowed from German ''Semasiologie'') is attested in Josiah W. Gibbs' '' ...
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MediaWiki Websites
MediaWiki is a free and open-source wiki software. It is used on Wikipedia and almost all other Wikimedia websites, including Wiktionary, Wikimedia Commons and Wikidata; these sites define a large part of the requirement set for MediaWiki. It was developed for use on Wikipedia in 2002, and given the name "MediaWiki" in 2003. MediaWiki was originally developed by Magnus Manske and improved by Lee Daniel Crocker. Magnus Manske's announcement of "PHP Wikipedia", wikipedia-l, August 24, 2001 Its development has since then been coordinated by the Wikimedia Foundation. MediaWiki is written in the PHP programming language and stores all text content into a database. The software is optimized to efficiently handle large projects, which can have terabytes of content and hundreds of thousands of views per second. Because Wikipedia is one of the world's largest websites, achieving scalability through multiple layers of caching and database replication has been a major concern for dev ...
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Neuroinformatics (journal)
''Neuroinformatics'' is a quarterly peer-reviewed scientific journal published by Springer Science+Business Media. It covers all aspects of neuroinformatics. The journal is abstracted and indexed in MEDLINE/PubMed, Scopus and the Science Citation Index Expanded. According to the ''Journal Citation Reports'', the journal has a 2020 impact factor of 4.085. The co-editors-in-chief An editor-in-chief (EIC), also known as lead editor or chief editor, is a publication's editorial leader who has final responsibility for its operations and policies. The highest-ranking editor of a publication may also be titled editor, managing ... are Giorgio A. Ascoli and Erik De Schutter. References External links * Neuroinformatics Neuroscience journals Springer Science+Business Media academic journals English-language journals Publications established in 2003 Quarterly journals {{compu-journal-stub ...
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NeuroNames
''NeuroNames'' is an integrated nomenclature for structures in the brain and spinal cord of the four species most studied by neuroscientists: human, macaque, rat and mouse. It offers a standard, controlled vocabulary of common names for structures, which is suitable for unambiguous neuroanatomical indexing of information in digital databases. Terms in the standard vocabulary have been selected for ease of pronunciation, mnemonic value, and frequency of use in recent neuroscientific publications. Structures and their relations to each other are defined in terms of the standard vocabulary. Currently NeuroNames contains standard names, synonyms and definitions of some 2,500 neuroanatomical entities. The nomenclature is maintained by the University of Washington and is the core component of a tool called "BrainInfo". BrainInfo helps one identify structures in the brain. One can either search by a structure name or locate the structure in a brain atlas and get information such as it ...
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Disease
A disease is a particular abnormal condition that negatively affects the structure or function of all or part of an organism, and that is not immediately due to any external injury. Diseases are often known to be medical conditions that are associated with specific signs and symptoms. A disease may be caused by external factors such as pathogens or by internal dysfunctions. For example, internal dysfunctions of the immune system can produce a variety of different diseases, including various forms of immunodeficiency, hypersensitivity, allergies and autoimmune disorders. In humans, ''disease'' is often used more broadly to refer to any condition that causes pain, dysfunction, distress, social problems, or death to the person affected, or similar problems for those in contact with the person. In this broader sense, it sometimes includes injuries, disabilities, disorders, syndromes, infections, isolated symptoms, deviant behaviors, and atypical variations of structur ...
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Nervous System
In biology, the nervous system is the highly complex part of an animal that coordinates its actions and sensory information by transmitting signals to and from different parts of its body. The nervous system detects environmental changes that impact the body, then works in tandem with the endocrine system to respond to such events. Nervous tissue first arose in wormlike organisms about 550 to 600 million years ago. In vertebrates it consists of two main parts, the central nervous system (CNS) and the peripheral nervous system (PNS). The CNS consists of the brain and spinal cord. The PNS consists mainly of nerves, which are enclosed bundles of the long fibers or axons, that connect the CNS to every other part of the body. Nerves that transmit signals from the brain are called motor nerves or '' efferent'' nerves, while those nerves that transmit information from the body to the CNS are called sensory nerves or '' afferent''. Spinal nerves are mixed nerves that serve both fu ...
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Cell (biology)
The cell is the basic structural and functional unit of life forms. Every cell consists of a cytoplasm enclosed within a membrane, and contains many biomolecules such as proteins, DNA and RNA, as well as many small molecules of nutrients and metabolites.Cell Movements and the Shaping of the Vertebrate Body
in Chapter 21 of
Molecular Biology of the Cell
'' fourth edition, edited by Bruce Alberts (2002) published by Garland Science. The Alberts text discusses how the "cellular building blocks" move to shape developing embryos. It is also common to describe small molecules such as ...
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Neuron
A neuron, neurone, or nerve cell is an electrically excitable cell that communicates with other cells via specialized connections called synapses. The neuron is the main component of nervous tissue in all animals except sponges and placozoa. Non-animals like plants and fungi do not have nerve cells. Neurons are typically classified into three types based on their function. Sensory neurons respond to stimuli such as touch, sound, or light that affect the cells of the sensory organs, and they send signals to the spinal cord or brain. Motor neurons receive signals from the brain and spinal cord to control everything from muscle contractions to glandular output. Interneurons connect neurons to other neurons within the same region of the brain or spinal cord. When multiple neurons are connected together, they form what is called a neural circuit. A typical neuron consists of a cell body (soma), dendrites, and a single axon. The soma is a compact structure, and the axon and dend ...
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