Nemertelline
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Nemertelline
Nemertelline is a neurotoxic tetra-pyridine compound originally found in the marine hoplonemertine worm '' Amphiporus angulatus''. These worms produce a variety of toxins which are used both in hunting their prey and in defending themselves from predators. Interest in potential application of this compound as an antifouling agent for boats and other marine installations has led to attempts to produce it synthetically by convenient routes. Its toxicity is similar to nicotine in crustaceans but has no mammalian toxicity. It is similar to nicotelline Nicotelline is an alkaloid first identified in 1914 as a chemical constituent of tobacco plants (''Nicotiana tabacum''). The chemical structure of nicotelline wasn't elucidated until 1956, when it was determined that nicotelline is a terpyridine ... in structure. References Pyridines Neurotoxins {{Neurotoxin-stub ...
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Neurotoxin
Neurotoxins are toxins that are destructive to nerve tissue (causing neurotoxicity). Neurotoxins are an extensive class of exogenous chemical neurological insultsSpencer 2000 that can adversely affect function in both developing and mature nervous tissue.Olney 2002 The term can also be used to classify endogenous compounds, which, when abnormally contacted, can prove neurologically toxic. Though neurotoxins are often neurologically destructive, their ability to specifically target neural components is important in the study of nervous systems. Common examples of neurotoxins include lead, ethanol (drinking alcohol), glutamate,Choi 1987 nitric oxide, botulinum toxin (e.g. Botox), tetanus toxin,Simpson 1986 and tetrodotoxin. Some substances such as nitric oxide and glutamate are in fact essential for proper function of the body and only exert neurotoxic effects at excessive concentrations. Neurotoxins inhibit neuron control over ion concentrations across the cell membrane, or com ...
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Pyridine
Pyridine is a basic heterocyclic organic compound with the chemical formula . It is structurally related to benzene, with one methine group replaced by a nitrogen atom. It is a highly flammable, weakly alkaline, water-miscible liquid with a distinctive, unpleasant fish-like smell. Pyridine is colorless, but older or impure samples can appear yellow, due to the formation of extended, unsaturated polymeric chains, which show significant electrical conductivity. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Historically, pyridine was produced from coal tar. As of 2016, it is synthesized on the scale of about 20,000 tons per year worldwide. Properties Physical properties The molecular electric dipole moment is 2.2 debyes. Pyridine is diamagnetic and has a diamagnetic susceptibility of −48.7 × 10−6 cm3·mol−1. The standard enthalpy of formation is 100.2 kJ·mol−1 in the liquid phase ...
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Amphiporus Angulatus
''Amphiporus'' is a genus of nemerteans belonging to the family Amphiporidae. The genus has cosmopolitan distribution In biogeography, cosmopolitan distribution is the term for the range of a taxon that extends across all or most of the world in appropriate habitats. Such a taxon, usually a species, is said to exhibit cosmopolitanism or cosmopolitism. The ext .... Species Species: *'' Amphiporus adriaticus'' *'' Amphiporus albicans'' *'' Amphiporus lactifloreus'' References Monostilifera Nemertea genera {{Nemertean-stub ...
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Antifouling Agent
Biofouling or biological fouling is the accumulation of microorganisms, plants, algae, or small animals where it is not wanted on surfaces such as ship and submarine hulls, devices such as water inlets, pipework, grates, ponds, and rivers that cause degradation to the primary purpose of that item. Such accumulation is referred to as '' epibiosis'' when the host surface is another organism and the relationship is not parasitic. Since biofouling can occur almost anywhere water is present, biofouling poses risks to a wide variety of objects such as boat hulls and equipment, medical devices and membranes, as well as to entire industries, such as paper manufacturing, food processing, underwater construction, and desalination plants. Anti-fouling is the ability of specifically designed materials (such as toxic biocide paints, or non-toxic paints) to remove or prevent biofouling. The buildup of biofouling on marine vessels poses a significant problem. In some instances, the hull stru ...
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Nicotelline
Nicotelline is an alkaloid first identified in 1914 as a chemical constituent of tobacco plants (''Nicotiana tabacum''). The chemical structure of nicotelline wasn't elucidated until 1956, when it was determined that nicotelline is a terpyridine consisting of three linked pyridine rings. This structure was confirmed by laboratory synthesis. Nicotelline has the molecular formula . It is a crystalline solid with a melting point of 147-148 °C. It is soluble in hot water, chloroform, ethanol, and benzene. Nicotelline has long been known to be a constituent of tobacco smoke. As such, it has recently been proposed as a biomarker In biomedical contexts, a biomarker, or biological marker, is a measurable indicator of some biological state or condition. Biomarkers are often measured and evaluated using blood, urine, or soft tissues to examine normal biological processes, ... or environmental tracer for particulate matter derived from tobacco smoke. References {{reflist Alka ...
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Experientia
''Cellular and Molecular Life Sciences'' is a peer-reviewed scientific journal covering cellular and molecular life sciences. It was established in 1945 as ''Experientia'', obtaining its current name in 1994. The Editors-in-chief are Roberto Bruzzone and Jean Leon Thomas. According to the ''Journal Citation Reports'', the journal has a 2020 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as i ... of 9.261. References External links * Molecular and cellular biology journals Publications established in 1945 Springer Science+Business Media academic journals Monthly journals English-language journals {{Molec-cell-biology-journal-stub ...
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Pyridines
Pyridine is a basic heterocyclic organic compound with the chemical formula . It is structurally related to benzene, with one methine group replaced by a nitrogen atom. It is a highly flammable, weakly alkaline, water-miscible liquid with a distinctive, unpleasant fish-like smell. Pyridine is colorless, but older or impure samples can appear yellow, due to the formation of extended, unsaturated polymeric chains, which show significant electrical conductivity. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Historically, pyridine was produced from coal tar. As of 2016, it is synthesized on the scale of about 20,000 tons per year worldwide. Properties Physical properties The molecular electric dipole moment is 2.2 debyes. Pyridine is diamagnetic and has a diamagnetic susceptibility of −48.7 × 10−6 cm3·mol−1. The standard enthalpy of formation is 100.2 kJ·mol−1 in the liquid phase ...
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