|
Negative Pressure Pulmonary Edema
Negative-pressure pulmonary edema (NPPE), also known as Postobstructive Pulmonary Edema, is a clinical phenomenon that results from the generation of large negative pressures in the airways during attempted inspiration against some form of obstruction of the upper airways. The most common reported cause of NPPE reported in adults is laryngospasm, while the most implicated causes in children are infectious croup and epiglottitis. The large negative pressures created in the airways by inhalation against an upper airway obstruction can lead to fluid being drawn from blood vessels supplying the lungs into the alveoli, causing pulmonary edema and impaired ability for oxygen exchange (hypoxemia). The main treatment for NPPE is supportive care in an intensive care unit and can be fatal without intervention. Physiology NPPE develops as a result of significant negative pressure generated in the chest cavity by inspiration against an upper airway obstruction. These negative pressures in the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
|
|
Laryngospasm
Laryngospasm is an uncontrolled or involuntary muscular contraction (spasm) of the vocal folds. The condition typically lasts less than 60 seconds, but in cases partial blocking it may last 20 to 30 minutes and hinder inspiration, while exhalation remains easier. It may be triggered when the vocal cords or the area of the trachea below the vocal folds detects the entry of water, mucus, blood, or other substance. It is characterized by stridor or retractions. Some people have frequent laryngospasms, whether awake or asleep. In an ear, nose, and throat practice, it is typically seen in people who have silent reflux disease. It is also a well known, infrequent, but serious perioperative complication. It is likely that more than 10% of drownings involve laryngospasm, but the evidence suggests that it is not usually effective at preventing water from entering the trachea. Signs and symptoms Laryngospasm is characterized by involuntary spasms of the laryngeal muscles. It is as ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |