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Nef DMDO
Nef or NEF may refer to: Businesses and organizations * National Energy Foundation, a British charity * National Enrichment Facility, an American uranium enrichment plant * New Economics Foundation, a British think-tank * Near East Foundation, an American international social and economic development organization * National Equity Fund, Inc., an American non-profit syndicator of Low Income Housing Tax Credits * New England Firearms, a brand of H&R Firearms People * Abdou Nef (1995–2013), Algerian footballer * Adolfo Nef (born 1946), Chilean football goalkeeper * Alain Nef (born 1982), Swiss footballer * Francisco Nef (1863–1931), Chilean naval officer and member of the government junta ** Hospital Naval Almirante Nef * Hari Nef (born 1992), American actress, model, and writer * Isabelle Nef (1895–1976), Swiss pianist and harpsichordist * John Ulric Nef (chemist) (1862–1915), discoverer of the Nef reaction * John Ulric Nef (economic historian) (1899–1988) * Karl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Energy Foundation
The National Energy Foundation (NEF) is an independent British charity, established to improve the use of energy in buildings. Aims The charity aims to ''improve the use of energy in buildings''. This statement simplified the earlier stated mission to mobilise individuals, businesses and communities to make their contribution to reducing carbon dioxide emissions through energy efficiency and use of sustainable energy sources (notably renewable energy) to maintain affordable energy services and combat global climate change. Activities NEF was founded in 1988 by Milton Keynes Development Corporation to preserve for the future benefit of the UK public some of the energy initiatives that had been undertaken within the new city. Its initial projects included extending a technical home energy label (known as the Milton Keynes Energy Cost Index – MKECI) into a more generally applicable home energy rating called the National Home Energy Rating (NHER), and technical energy moni ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sonja Nef
Sonja Nef (born 19 April 1972) is a Swiss former alpine skier. Nef was women's World Champion in Giant Slalom in 2001. She won the 2001 and 2002 World Cup in Giant Slalom. At the 2002 Winter Olympics The 2002 Winter Olympics, officially the XIX Olympic Winter Games and commonly known as Salt Lake 2002 ( arp, Niico'ooowu' 2002; Gosiute Shoshoni: ''Tit'-so-pi 2002''; nv, Sooléí 2002; Shoshoni: ''Soónkahni 2002''), was an internation ..., she finished third in Giant Slalom. Career The injury made itself felt in the following winter of 2003/04 in a declining level of performance. Although Nef was able to achieve a podium finish in the slalom for the last time, further good results became rarer. This trend continued in the winter of 2004/05. Her best placings were two fifth places. In the 2005/06 season, an inflammation of her hip gave her a hard time. Nef was never ranked better than 20th and was unable to qualify for the 2006 Winter Olympics. World Cup results S ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nef Line Bundle
In algebraic geometry, a line bundle on a projective variety is nef if it has nonnegative degree on every curve in the variety. The classes of nef line bundles are described by a convex cone, and the possible contractions of the variety correspond to certain faces of the nef cone. In view of the correspondence between line bundles and divisors (built from codimension-1 subvarieties), there is an equivalent notion of a nef divisor. Definition More generally, a line bundle ''L'' on a proper scheme ''X'' over a field ''k'' is said to be nef if it has nonnegative degree on every (closed irreducible) curve in ''X''. (The degree of a line bundle ''L'' on a proper curve ''C'' over ''k'' is the degree of the divisor (''s'') of any nonzero rational section ''s'' of ''L''.) A line bundle may also be called an invertible sheaf. The term "nef" was introduced by Miles Reid as a replacement for the older terms "arithmetically effective" and "numerically effective", as well as for the phrase ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
S100B
S100 calcium-binding protein B (S100B) is a protein of the S-100 protein family. S100 proteins are localized in the cytoplasm and nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. Function S100B is glial-specific and is expressed primarily by astrocytes, but not all astrocytes express S100B. It has been shown that S100B is only expressed by a subtype of mature astrocytes that ensheath blood vessels and by NG2-expressing cells. This protein may function in neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. In the developing CNS it acts as a neurotrophic factor and neuronal survival protein. In th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nucleotide Exchange Factor
Nucleotide exchange factors (NEFs) are proteins that stimulate the exchange (replacement) of nucleoside diphosphates for nucleoside triphosphates bound to other proteins. Function Many cellular proteins cleave (hydrolyze) nucleoside triphosphates–adenosine triphosphate (ATP) or guanosine triphosphate (GTP)–to their diphosphate forms (ADP and GDP) as a source of energy and to drive conformational changes. These changes in turn affect the structural, enzymatic, or signalling properties of the protein. Nucleotide exchange factors actively assist in the exchange of depleted nucleoside diphosphates for fresh nucleoside triphosphates. NEFs are specific for the nucleotides they exchange (ADP or GDP, but not both) and are often specific to a single protein or class of proteins with which they interact. See also * Nucleoside-diphosphate kinase Nucleoside-diphosphate kinases (NDPKs, also NDP kinase, (poly)nucleotide kinases and nucleoside diphosphokinases) are enzymes t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nef Isocyanide Reaction
The Nef isocyanide reaction is an addition reaction that takes place between isocyanides and acyl chlorides to form imidoyl chloride products, a process first discovered by John Ulrich Nef. The product imidoyl chloride can be hydrolyzed to give the amide, trapped with other nucleophiles, or undergo halide abstraction with silver salts to form an acyl nitrilium intermediate. The reaction is of some theoretical interest, as kinetic measurements and DFT studies have indicated that the addition occurs in one step, without the intermediacy of a tetrahedral intermediate that is commonly proposed for carbonyl addition reactions. See also * Carbene * Insertion reaction * Nef reaction In organic chemistry, the Nef reaction is an organic reaction describing the acid hydrolysis of a salt of a primary or secondary nitroalkane () to an aldehyde () or a ketone () and nitrous oxide (). The reaction has been the subject of several ... References {{reflist Carbon-carbon bond form ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nef Synthesis
In organic chemistry, Nef synthesis is the addition of sodium acetylides to aldehydes and ketones to yield acetylenic carbinols. It is named for John Ulric Nef, who discovered the reaction in 1899. This process is often erroneously referred to as the Nef reaction In organic chemistry, the Nef reaction is an organic reaction describing the acid hydrolysis of a salt of a primary or secondary nitroalkane () to an aldehyde () or a ketone () and nitrous oxide (). The reaction has been the subject of several ..., which is an unrelated chemical transformation discovered by the same chemist. See also * Alkynation References Carbon-carbon bond forming reactions Organometallic chemistry Addition reactions {{organic-chem-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nef Reaction
In organic chemistry, the Nef reaction is an organic reaction describing the acid hydrolysis of a salt of a primary or secondary nitroalkane () to an aldehyde () or a ketone () and nitrous oxide (). The reaction has been the subject of several literature reviews. The reaction was reported in 1894 by the chemist John Ulric Nef, who treated the sodium salt of nitroethane with sulfuric acid resulting in an 85–89% yield of nitrous oxide and at least 70% yield of acetaldehyde. However, the reaction was pioneered a year earlier in 1893 by Konovalov, who converted the potassium salt of 1-phenylnitroethane with sulfuric acid to acetophenone. Reaction mechanism The reaction mechanism starting from the nitronate salt as the resonance structures 1a and 1b is depicted below: The salt is protonated forming the nitronic acid 2 (in some cases these nitronates have been isolated) and once more to the iminium ion 3. This intermediate is attacked by water in a nucleophilic addi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nef (protein)
Nef (Negative Regulatory Factor) is a small 27-35 kDa myristoylated protein encoded by primate lentiviruses. These include Human Immunodeficiency Viruses (HIV-1 and HIV-2) and Simian Immunodeficiency Virus (SIV). Nef localizes primarily to the cytoplasm but also partially to the Plasma membrane (PM) and is one of many pathogen-expressed proteins, known as virulence factors, which function to manipulate the host's cellular machinery and thus allow infection, survival or replication of the pathogen. Nef stands for "Negative Factor" and although it is often considered indispensable for HIV-1 replication, in infected hosts the viral protein markedly elevates viral titers. Function The expression of Nef early in the viral life cycle ensures T-cell activation and the establishment of a persistent state of infection, two basic attributes of HIV infection. Viral expression of Nef induces numerous changes within the infected cell including the modulation of protein cell surface expr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nef River
The Nef River is a river of Chile. The river has its source at a proglacial lake, which is feed by Nef Glacier Nef Glacier is a glacier located in Laguna San Rafael National Park, in the Aysén del General Carlos Ibáñez del Campo Region of Chile. It trends southeast from Cerro Largo to its terminus in the lake that shared its name. It is the fifth large .... It flows in a generally easterly direction until it discharges into the Baker River. See also * List of rivers of Chile Rivers of Chile Rivers of Aysén Region {{Chile-river-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nef Glacier
Nef Glacier is a glacier located in Laguna San Rafael National Park, in the Aysén del General Carlos Ibáñez del Campo Region of Chile. It trends southeast from Cerro Largo to its terminus in the lake that shared its name. It is the fifth largest glacier in the Northern Patagonian Ice Field, after San Quintín, San Rafael, Steffen and Colonia. See also *Glaciers of Chile The glaciers of Chile cover 2.7% (20,188 km2) of the land area of the country, excluding Antártica Chilena, and have a considerable impact on its landscape and water supply. By surface 80% of South America's glaciers lie in Chile. Glaciers d ... References External linksPhoto Gallery Glaciers of Aysén Region {{chile-glacier-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nef The Pharaoh
Tonee Hayes (born January 11, 1995), better known by his stage name Nef the Pharaoh, is an American rapper from Vallejo, California. In 2014 he was selected by fans as the "Bay Area Freshman of the Year" in a yearly contest held by Thizzler.com. In early 2015, his track "Big Tymin'" became a regional hit, with a music video released shortly after Nef the Pharaoh signed with Sick Wid It Records. "Big Tymin'" was remixed by YG and Ty Dolla $ign in July 2015, and his self-titled debut EP was released on Sick Wid It on November 6, 2015. He released his full-length debut album titled ''The Chang Project'' on April 27, 2017. Early life Tonee Hayes was born on January 11, 1995 in Oakland, California. He was featured on the cover of the '' Vallejo Times-Herald'' at the age of 17. Hayes has cited Vallejo rappers like Mac Dre and E-40 as significant influences on his style. He was given the nickname Nef (short for nephew) from his uncle, which he incorporated into part of his stage name. H ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
