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Navigenics
Navigenics, Inc. was a privately held personal genomics company, based in Foster City, California, that used genetic testing to help people determine their individual risk for dozens of health conditions.Navigenics, Inc"Navigenics launches Health Compass service." Retrieved 2008-10-15. History Navigenics was co-founded in 2006 by David Agus, M.D., a prostate cancer specialist who is a Professor of Medicine at the University of Southern California and Director of the USC Center for Applied Molecular Medicine and the USC Westside Prostate Cancer Center in Los Angeles, and Dietrich Stephan, Ph.D., member of the Board of Directors of the Personalized Medicine Coalition, current CEO of Silicon Valley Biosystems, former Chairman of Neurogenomics and Deputy Director for Discovery Research at the Translational Genomics Research Institute. In July 2012, Navigenics was acquired by Life Technologies, which was acquired by Thermo Fisher Scientific in February, 2014. Controversy in C ...
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Dietrich Stephan
Dietrich A. Stephan (born August 25, 1969) is an American human geneticist and entrepreneur who works in personalized medicine. Stephan is currently CEO of NeuBase Therapeutics and a General Partner in Cyto Ventures. Before NeuBase, Stephan was CEO of LifeX and Chairman and Professor of Human Genetics at the University of Pittsburgh. Prior, he was founding Chairman of the Neurogenomics Division at the Translational Genomics Research Institute. Stephan has founded or co-founded 14 biotechnology companies and advised many others. Stephan was co-founder of Navigenics, a personal genetics company. Academic career Stephan received his B.Sc. in Biology from Carnegie Mellon University and his Ph.D. in Human Molecular Genetics from the University of Pittsburgh, followed by a fellowship at the National Human Genome Research Institute. In 2003, Stephan worked at Translational Genomics Research Institute (TGen) as a Senior Investigator and founding Chairman of the Department of Neuroge ...
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David Agus
David B. Agus () is an American physician and author who serves as a professor of medicine and engineering at the University of Southern California Keck School of Medicine and Viterbi School of Engineering and the Founding Director and CEO of the Lawrence J. Ellison Institute for Transformative Medicine. He is also the cofounder of several personalized medicine companies and a contributor to CBS News on health topics. Agus’s field of expertise is advanced cancer. He has developed new cancer treatments with the aid of private foundations, as well as national agencies including the National Cancer Institute. Agus has also served as chair of the Global Agenda Council on Genetics for the World Economic Forum.   He is also the author of three New York Times best selling books. Early life and education Agus graduated cum laude in molecular biology from Princeton University in 1987 and received his medical degree from the University of Pennsylvania Perelman School of Medicine in 1 ...
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Personal Genomics
Personal genomics or consumer genetics is the branch of genomics concerned with the sequencing, analysis and interpretation of the genome of an individual. The genotyping stage employs different techniques, including single-nucleotide polymorphism (SNP) analysis chips (typically 0.02% of the genome), or partial or full genome sequencing. Once the genotypes are known, the individual's variations can be compared with the published literature to determine likelihood of trait expression, ancestry inference and disease risk. Automated high-throughput sequencers have increased the speed and reduced the cost of sequencing, making it possible to offer whole genome sequencing including interpretation to consumers since 2015 for less than $1,000. The emerging market of direct-to-consumer genome sequencing services has brought new questions about both the medical efficacy and the ethical dilemmas associated with widespread knowledge of individual genetic information. In personalized medi ...
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Foster City, California
Foster City is a city located in San Mateo County, California. The 2020 census put the population at 33,805, an increase of more than 10% over the 2010 census figure of 30,567. Foster City is sometimes considered to be part of Silicon Valley for its local industry and its proximity to Silicon Valley cities. Foster City is one of the United States’ safest cities, with an average of one murder per decade. History Foster City was founded in the 1960s, built on the existing Brewer Island in the marshes of the San Francisco Bay on the east edge of San Mateo, enlarged with engineered landfill. The city was named after T. Jack Foster, a real estate magnate who owned much of the land comprising the city and who was instrumental in its initial design. His firm, Foster Enterprises, now run by his descendants, relocated to San Mateo in 2000 and is still active in real estate affairs throughout the San Francisco Bay Area. Geography According to the United States Census Bureau, the c ...
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Life Technologies (Thermo Fisher Scientific)
Life Technologies Corporation was a biotech company founded in November 2008 through a US $6.7billion merger of Invitrogen Corporation and Applied Biosystems Inc. The joint sales of the combined companies were about $3.5 billion; they had about 9,500 employees and owned more than 3,600 licenses and patents. Company name The name "Life Technologies" was an old name from the history of Invitrogen. GIBCO (Grand Island Biological Company) had been founded around 1960 in New York; in 1983 GIBCO merged with a reagent company called Bethesda Research Laboratories and the merged company was named Life Technologies. In 2000, Invitrogen acquired Life Technologies and discontinued that name. When Invitrogen and Applied Biosystems merged, the companies revived the name. The use of the "Life Technologies" brand name is disputed. Life Technologies (India) Private Limited, a company founded in 2002, operating in this corporate name claims ownership of the brand name. The "Life Technologies" ...
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Technology Companies Based In The San Francisco Bay Area
Technology is the application of knowledge to reach practical goals in a specifiable and reproducible way. The word ''technology'' may also mean the product of such an endeavor. The use of technology is widely prevalent in medicine, science, industry, communication, transportation, and daily life. Technologies include physical objects like utensils or machines and intangible tools such as software. Many technological advancements have led to societal changes. The earliest known technology is the stone tool, used in the prehistoric era, followed by fire use, which contributed to the growth of the human brain and the development of language in the Ice Age. The invention of the wheel in the Bronze Age enabled wider travel and the creation of more complex machines. Recent technological developments, including the printing press, the telephone, and the Internet have lowered communication barriers and ushered in the knowledge economy. While technology contributes to economic deve ...
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Biotechnology Companies Of The United States
Biotechnology is the integration of natural sciences and engineering sciences in order to achieve the application of organisms, cells, parts thereof and molecular analogues for products and services. The term ''biotechnology'' was first used by Károly Ereky in 1919, meaning the production of products from raw materials with the aid of living organisms. Definition The concept of biotechnology encompasses a wide range of procedures for modifying living organisms according to human purposes, going back to domestication of animals, cultivation of the plants, and "improvements" to these through breeding programs that employ artificial selection and hybridization. Modern usage also includes genetic engineering as well as cell and tissue culture technologies. The American Chemical Society defines biotechnology as the application of biological organisms, systems, or processes by various industries to learning about the science of life and the improvement of the value of materials ...
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Genomics Companies
Genomics is an interdisciplinary field of biology focusing on the structure, function, evolution, mapping, and editing of genomes. A genome is an organism's complete set of DNA, including all of its genes as well as its hierarchical, three-dimensional structural configuration. In contrast to genetics, which refers to the study of ''individual'' genes and their roles in inheritance, genomics aims at the collective characterization and quantification of ''all'' of an organism's genes, their interrelations and influence on the organism. Genes may direct the production of proteins with the assistance of enzymes and messenger molecules. In turn, proteins make up body structures such as organs and tissues as well as control chemical reactions and carry signals between cells. Genomics also involves the sequencing and analysis of genomes through uses of high throughput DNA sequencing and bioinformatics to assemble and analyze the function and structure of entire genomes. Advances in gen ...
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23andMe
23andMe Holding Co. is a publicly held personal genomics and biotechnology company based in South San Francisco, California. It is best known for providing a direct-to-consumer genetic testing service in which customers provide a saliva sample that is laboratory analysed, using single nucleotide polymorphism genotyping, to generate reports relating to the customer's ancestry and genetic predispositions to health-related topics. The company's name is derived from the 23 pairs of chromosomes in a wild-type human cell. The company had a previously fraught relationship with the United States Food and Drug Administration (FDA) due to its genetic health tests; as of October 2015, DNA tests ordered in the US include a revised health component, per FDA approval. 23andMe has been selling a product with both ancestry and health-related components in Canada since October 2014, and in the UK since December 2014. In 2007, 23andMe became the first company to begin offering autosomal DNA tes ...
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Thermo Fisher Scientific
Thermo Fisher Scientific Inc. is an American supplier of scientific instrumentation, reagents and consumables, and software services. Based in Waltham, Massachusetts, Thermo Fisher was formed through the merger of Thermo Electron and Fisher Scientific in 2006. Thermo Fisher Scientific has acquired other reagent, consumable, instrumentation, and service providers, including: Life Technologies Corporation (2013), Alfa Aesar (2015), Affymetrix (2016), FEI Company (2016), BD Advanced Bioprocessing (2018), and PPD (2021). As of 2017, the company had a market capitalization of $21 billion and was a Fortune 500 company. Annual revenue in 2021 was US$39.21 billion. In March 2020, Thermo Fisher Scientific received emergency use authorization from the FDA for a test for SARS-CoV-2 to help mitigate the COVID-19 pandemic. History Predecessors and merger Thermo Electron was co-founded in 1956 by George N. Hatsopoulos and Peter M Nomikos. Hatsopoulos received a PhD from MIT in me ...
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Public Company
A public company is a company whose ownership is organized via shares of stock which are intended to be freely traded on a stock exchange or in over-the-counter markets. A public (publicly traded) company can be listed on a stock exchange (listed company), which facilitates the trade of shares, or not (unlisted public company). In some jurisdictions, public companies over a certain size must be listed on an exchange. In most cases, public companies are ''private'' enterprises in the ''private'' sector, and "public" emphasizes their reporting and trading on the public markets. Public companies are formed within the legal systems of particular states, and therefore have associations and formal designations which are distinct and separate in the polity in which they reside. In the United States, for example, a public company is usually a type of corporation (though a corporation need not be a public company), in the United Kingdom it is usually a public limited company (plc), i ...
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