National Firefighter Registry
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National Firefighter Registry
The National Firefighter Registry (NFR) is a voluntary registry of firefighters in the United States used to collect relevant occupational, lifestyle, and health information on firefighters for evaluating cancer rates and cancer risk factors in the U.S. fire service. It aims to use this data to reduce cancer in firefighters. The NFR was created by the Firefighter Cancer Registry Act of 2018 in response to growing evidence of carcinogenic exposures and increased risk for cancer faced by firefighters. It is expected to begin registering firefighters in 2022. The NFR is maintained by the U.S. National Institute for Occupational Safety and Health (NIOSH). Cancer among firefighters Cancer risk in the U.S. fire service is a topic of growing concern. Recent studies suggest that exposure on the fireground may increase risk to firefighters of certain types of cancer and other chronic diseases. Major international studies generally support findings from U.S. studies that firefighters ...
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National Institute For Occupational Safety And Health
The National Institute for Occupational Safety and Health (NIOSH, ) is the United States federal agency responsible for conducting research and making recommendations for the prevention of work-related injury and illness. NIOSH is part of the Centers for Disease Control and Prevention (CDC) within the U.S. Department of Health and Human Services. Despite its name, it is not part of the National Institutes of Health. Its current director is John Howard. NIOSH is headquartered in Washington, D.C., with research laboratories and offices in Cincinnati, Ohio; Morgantown, West Virginia; Pittsburgh, Pennsylvania; Denver, Colorado; Anchorage, Alaska; Spokane, Washington; and Atlanta, Georgia. NIOSH is a professionally diverse organization with a staff of 1,200 people representing a wide range of disciplines including epidemiology, medicine, industrial hygiene, safety, psychology, engineering, chemistry, and statistics. The Occupational Safety and Health Act, signed by President Rich ...
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Particulates
Particulates – also known as atmospheric aerosol particles, atmospheric particulate matter, particulate matter (PM) or suspended particulate matter (SPM) – are microscopic particles of solid or liquid matter suspended in the air. The term '' aerosol'' commonly refers to the particulate/air mixture, as opposed to the particulate matter alone. Sources of particulate matter can be natural or anthropogenic. They have impacts on climate and precipitation that adversely affect human health, in ways additional to direct inhalation. Types of atmospheric particles include suspended particulate matter; thoracic and respirable particles; inhalable coarse particles, designated PM, which are coarse particles with a diameter of 10 micrometers (μm) or less; fine particles, designated PM, with a diameter of 2.5 μm or less; ultrafine particles, with a diameter of 100 nm or less; and soot. The IARC and WHO designate airborne particulates as a Group 1 carcinogen. Particula ...
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Chris Collins (New York Politician)
Christopher Carl Collins (born May 20, 1950) is an American politician, businessman, and convicted felon who served as the U.S. representative for New York's 27th congressional district from 2013 until his resignation in 2019. Collins was elected Erie County Executive in 2007 and held that position for one term. A member of the Republican Party, Collins was the first sitting U.S. Representative to endorse Donald Trump for President of the United States, and he served on Trump's presidential transition team. He resigned his seat in 2019 and afterwards pleaded guilty to insider trading and lying to the FBI. Collins and his son, Cameron Collins, were arrested by the Federal Bureau of Investigation on August 8, 2018, and charged with insider trading and making false statements. Three days later, Collins announced that he was suspending his bid for a fourth term in Congress; however, on September 17, 2018, he resumed his re-election campaign. Collins was narrowly re-elected to Cong ...
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United States House Committee On Energy And Commerce
The Committee on Energy and Commerce is one of the oldest standing committees of the United States House of Representatives. Established in 1795, it has operated continuously—with various name changes and jurisdictional changes—for more than 200 years. The two other House standing committees with such continuous operation are the House Ways and Means Committee and the House Rules Committee. The committee has served as the principal guide for the House in matters relating to the promotion of commerce and to the public's health and marketplace interests, with the relatively recent addition of energy considerations among them. Role of the committee The House Committee on Energy and Commerce has developed what is arguably the broadest (non-tax-oriented) jurisdiction of any congressional committee. The committee maintains principal responsibility for legislative oversight relating to telecommunications, consumer protection, food and drug safety, public health, air quality and env ...
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Voice Vote
In parliamentary procedure, a voice vote (from the Latin ''viva voce'', meaning "live voice") or acclamation is a voting method in deliberative assemblies (such as legislatures) in which a group vote is taken on a topic or motion by responding vocally. The voice vote is considered the simplest and quickest of voting methods used by deliberative assemblies. The presiding officer or chair of the assembly will put the question to the assembly, asking first for all those in favor of the motion to indicate so orally ("aye" or "yea"), and then ask second all those opposed to the motion to indicate so verbally ("no" or "nay"). The chair will then make an estimate of the count on each side and state what they believe the result to be. Voice votes have inherent disadvantages and the method has major shortfalls in close contests. The volume of the voices are typically only estimated and not actually measured with sound level meters, giving a chair enough plausible deniability to falsify ...
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Unanimous Consent
In parliamentary procedure, unanimous consent, also known as general consent, or in the case of the parliaments under the Westminster system, leave of the house (or leave of the senate), is a situation in which no member present objects to a proposal. Purpose Generally, in a meeting of a deliberative assembly, business is conducted using a formal procedure of motion, debate, and vote. However, if there are no objections, action could be taken by unanimous consent. The procedure of asking for unanimous consent is used to expedite business by eliminating the need for formal votes on routine questions in which the existence of a consensus is likely. The principle behind it is that procedural safeguards designed to protect a minority can be waived when there is no minority to protect. In non-legislative deliberative bodies operating under ''Robert's Rules of Order'', unanimous consent is often used to expedite the consideration of uncontroversial motions. It is sometimes used simp ...
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Donald Trump
Donald John Trump (born June 14, 1946) is an American politician, media personality, and businessman who served as the 45th president of the United States from 2017 to 2021. Trump graduated from the Wharton School of the University of Pennsylvania with a bachelor's degree in 1968. He became president of his father's real estate business in 1971 and renamed it The Trump Organization. He expanded the company's operations to building and renovating skyscrapers, hotels, casinos, and golf courses. He later started side ventures, mostly by licensing his name. From 2004 to 2015, he co-produced and hosted the reality television series ''The Apprentice (American TV series), The Apprentice''. Trump and his businesses have been involved in more than 4,000 state and federal legal actions, including six bankruptcies. Trump's political positions have been described as populist, protectionist, isolationist, and nationalist. He won the 2016 United States presidential election as the Repu ...
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Epigenetics
In biology, epigenetics is the study of stable phenotypic changes (known as ''marks'') that do not involve alterations in the DNA sequence. The Greek prefix '' epi-'' ( "over, outside of, around") in ''epigenetics'' implies features that are "on top of" or "in addition to" the traditional genetic basis for inheritance. Epigenetics most often involves changes that affect the regulation of gene expression, but the term can also be used to describe any heritable phenotypic change. Such effects on cellular and physiological phenotypic traits may result from external or environmental factors, or be part of normal development. The term also refers to the mechanism of changes: functionally relevant alterations to the genome that do not involve mutation of the nucleotide sequence. Examples of mechanisms that produce such changes are DNA methylation and histone modification, each of which alters how genes are expressed without altering the underlying DNA sequence. Gene expression c ...
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Oxidative Stress
Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species and a biological system's ability to readily Detoxification, detoxify the reactive intermediates or to repair the resulting damage. Disturbances in the normal redox state of cells can cause toxic effects through the production of peroxides and free radicals that damage all components of the cell, including proteins, lipids, and DNA. Oxidative stress from Cellular respiration, oxidative metabolism causes base damage, as well as DNA damage (naturally occurring), strand breaks in DNA. Base damage is mostly indirect and caused by the reactive oxygen species generated, e.g., O2− (superoxide radical), OH (hydroxyl radical) and H2O2 (hydrogen peroxide). Further, some reactive oxidative species act as cellular messengers in redox signaling. Thus, oxidative stress can cause disruptions in normal mechanisms of cellular signaling. In humans, oxidative stress is thought to be involved in the ...
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DNA Damage
DNA repair is a collection of processes by which a cell identifies and corrects damage to the DNA molecules that encode its genome. In human cells, both normal metabolic activities and environmental factors such as radiation can cause DNA damage, resulting in tens of thousands of individual molecular lesions per cell per day. Many of these lesions cause structural damage to the DNA molecule and can alter or eliminate the cell's ability to transcribe the gene that the affected DNA encodes. Other lesions induce potentially harmful mutations in the cell's genome, which affect the survival of its daughter cells after it undergoes mitosis. As a consequence, the DNA repair process is constantly active as it responds to damage in the DNA structure. When normal repair processes fail, and when cellular apoptosis does not occur, irreparable DNA damage may occur, including double-strand breaks and DNA crosslinkages (interstrand crosslinks or ICLs). This can eventually lead to maligna ...
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Biomarker
In biomedical contexts, a biomarker, or biological marker, is a measurable indicator of some biological state or condition. Biomarkers are often measured and evaluated using blood, urine, or soft tissues to examine normal biological processes, pathogenic processes, or pharmacologic responses to a therapeutic intervention. as cited in Biomarkers are used in many scientific fields. Medicine Biomarkers used in the medical field, are a part of a relatively new clinical toolset categorized by their clinical applications. The three main classes are molecular biomarkers, cellular biomarkers or imaging biomarkers. All three types of biomarkers have a clinical role in narrowing or guiding treatment decisions and follow a sub-categorization of being either predictive, prognostic, or diagnostic. Predictive Predictive molecular, cellular, or imaging biomarkers that pass validation can serve as a method of predicting clinical outcomes. Predictive biomarkers are used to help optimize id ...
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Epidemiology
Epidemiology is the study and analysis of the distribution (who, when, and where), patterns and determinants of health and disease conditions in a defined population. It is a cornerstone of public health, and shapes policy decisions and evidence-based practice by identifying risk factors for disease and targets for preventive healthcare. Epidemiologists help with study design, collection, and statistical analysis of data, amend interpretation and dissemination of results (including peer review and occasional systematic review). Epidemiology has helped develop methodology used in clinical research, public health studies, and, to a lesser extent, basic research in the biological sciences. Major areas of epidemiological study include disease causation, transmission, outbreak investigation, disease surveillance, environmental epidemiology, forensic epidemiology, occupational epidemiology, screening, biomonitoring, and comparisons of treatment effects such as in clinical trials. ...
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