National Collection Of Type Cultures
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National Collection Of Type Cultures
National Collection of Type Cultures (NCTC) is one of the four culture collections that constitutes the Culture Collections operated by Public Health England. It is a non-profit culture collection repository located in the UK. NCTC maintains over 5100 bacterial cultures, over 100 Mycoplasmas and more than 500 plasmids, host strains, bacteriophages and transposons. Of these, 150 strains are available from NCTC in the form of bacterial DNA, supplied at 2 µg, making them suitable for whole genome sequencing amongst other molecular applications. The cultures represent bacteria from widespread geographical locations and are transported in fused-glass ampoules. The NCTC was founded in 1920, with John Charles Grant Ledingham, who was previously chief bacteriologist at the Lister Institute, serving as its first director. The Lister Institute, along with the Medical Research Council, oversaw the founding of the collection. The first strain to be added to the collection—termed ''N ...
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Public Health England
Public Health England (PHE) was an executive agency of the Department of Health and Social Care in England which began operating on 1 April 2013 to protect and improve health and wellbeing and reduce health inequalities. Its formation came as a result of the reorganisation of the National Health Service (NHS) in England outlined in the Health and Social Care Act 2012. It took on the role of the Health Protection Agency, the National Treatment Agency for Substance Misuse and a number of other health bodies. It was an executive agency of the Department of Health and Social Care, and a distinct delivery organisation with operational autonomy. On 29 March 2021, the UK Government announced that PHE would be disbanded and that its public health functions would be transferred, in proposals to reform public health structures. From 1 October 2021, PHE's health protection functions were formally transferred into the UK Health Security Agency (UKHSA), while its health improvement functio ...
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The Wikipedia Library
Wikipedia is a multilingual free online encyclopedia written and maintained by a community of volunteers, known as Wikipedians, through open collaboration and using a wiki-based editing system. Wikipedia is the largest and most-read reference work in history. It is consistently one of the 10 most popular websites ranked by Similarweb and formerly Alexa; Wikipedia was ranked the 5th most popular site in the world. It is hosted by the Wikimedia Foundation, an American non-profit organization funded mainly through donations. Wikipedia was launched by Jimmy Wales and Larry Sanger on January 15, 2001. Sanger coined its name as a blend of ''wiki'' and ''encyclopedia''. Wales was influenced by the "spontaneous order" ideas associated with Friedrich Hayek and the Austrian School of economics after being exposed to these ideas by the libertarian economist Mark Thornton. Initially available only in English, versions in other languages were quickly developed. Its combined editions co ...
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Culture Collections
A microbiological culture, or microbial culture, is a method of multiplying microbial organisms by letting them reproduce in predetermined culture medium under controlled laboratory conditions. Microbial cultures are foundational and basic diagnostic methods used as a research tool in molecular biology. The term ''culture'' can also refer to the microorganisms being grown. Microbial cultures are used to determine the type of organism, its abundance in the sample being tested, or both. It is one of the primary diagnostic methods of microbiology and used as a tool to determine the cause of infectious disease by letting the agent multiply in a predetermined medium. For example, a throat culture is taken by scraping the lining of tissue in the back of the throat and blotting the sample into a medium to be able to screen for harmful microorganisms, such as ''Streptococcus pyogenes'', the causative agent of strep throat. Furthermore, the term culture is more generally used informally ...
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Biological Research Institutes In The United Kingdom
Biology is the scientific study of life. It is a natural science with a broad scope but has several unifying themes that tie it together as a single, coherent field. For instance, all organisms are made up of cells that process hereditary information encoded in genes, which can be transmitted to future generations. Another major theme is evolution, which explains the unity and diversity of life. Energy processing is also important to life as it allows organisms to move, grow, and reproduce. Finally, all organisms are able to regulate their own internal environments. Biologists are able to study life at multiple levels of organization, from the molecular biology of a cell to the anatomy and physiology of plants and animals, and evolution of populations.Based on definition from: Hence, there are multiple subdisciplines within biology, each defined by the nature of their research questions and the tools that they use. Like other scientists, biologists use the scientific ...
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Plasmid
A plasmid is a small, extrachromosomal DNA molecule within a cell that is physically separated from chromosomal DNA and can replicate independently. They are most commonly found as small circular, double-stranded DNA molecules in bacteria; however, plasmids are sometimes present in archaea and eukaryotic organisms. In nature, plasmids often carry genes that benefit the survival of the organism and confer selective advantage such as antibiotic resistance. While chromosomes are large and contain all the essential genetic information for living under normal conditions, plasmids are usually very small and contain only additional genes that may be useful in certain situations or conditions. Artificial plasmids are widely used as vectors in molecular cloning, serving to drive the replication of recombinant DNA sequences within host organisms. In the laboratory, plasmids may be introduced into a cell via transformation. Synthetic plasmids are available for procurement over the int ...
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Lyophilized
Freeze drying, also known as lyophilization or cryodesiccation, is a low temperature dehydration process that involves freezing the product and lowering pressure, removing the ice by sublimation. This is in contrast to dehydration by most conventional methods that evaporate water using heat. Because of the low temperature used in processing, the rehydrated product retains much of its original qualities. When solid objects like strawberries are freeze dried the original shape of the product is maintained. If the product to be dried is a liquid, as often seen in pharmaceutical applications, the properties of the final product are optimized by the combination of excipients (i.e., inactive ingredients). Primary applications of freeze drying include biological (e.g., bacteria and yeasts), biomedical (e.g., surgical transplants), food processing (e.g., coffee) and preservation. History The Inca were freeze drying potatoes into chuño from the 13th century. The process involved mul ...
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Colindale, London
Colindale is a district in the London Borough of Barnet; its main shopping street on the A5 forming the borough boundary with neighbouring Brent. Colindale is a suburban area, and in recent years has had many new apartments built. It's also the location of the 1960s-1970s Grahame Park housing estate, built on former parts of Hendon Aerodrome. It is situated about northwest of Charing Cross, directly northwest of Hendon, to the south of Edgware and east of Queensbury. History Formerly in the borough and ancient parish of Hendon, the area was essentially the dale between Mill Hill and The Burroughs. By the middle of the 20th century, it had come to include that part of the Edgware Road between The Hyde and Burnt Oak. The area was originally called Collin Deep after the 16th-century family of John Collin. Until the 20th century, Colindale was without any buildings save for a large house called Colindale Lodge, Colindale Farm and a few cottages. A spelling with two Ls, 'Col ...
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Central Public Health Laboratory
Central is an adjective usually referring to being in the center of some place or (mathematical) object. Central may also refer to: Directions and generalised locations * Central Africa, a region in the centre of Africa continent, also known as Middle Africa * Central America, a region in the centre of America continent * Central Asia, a region in the centre of Eurasian continent * Central Australia, a region of the Australian continent * Central Belt, an area in the centre of Scotland * Central Europe, a region of the European continent * Central London, the centre of London * Central Region (other) * Central United States, a region of the United States of America Specific locations Countries * Central African Republic, a country in Africa States and provinces * Blue Nile (state) or Central, a state in Sudan * Central Department, Paraguay * Central Province (Kenya) * Central Province (Papua New Guinea) * Central Province (Solomon Islands) * Central Province, Sri La ...
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Elstree, Hertfordshire
Elstree is a large village in the Hertsmere borough of Hertfordshire, England. It is about northwest of central London on the former A5 road, that follows the course of Watling Street. In 2011, its population was 5,110. It forms part of the civil parish of Elstree and Borehamwood, originally known simply as Elstree. The village often lends its shorter name to businesses and amenities in the adjacent town of Borehamwood, and the names of Elstree and Borehamwood are used interchangeably. Elstree is perhaps best known for multiple Elstree Film Studio complexes, where many films were made, including BBC Elstree Centre, where the TV soap opera ''EastEnders'' is shot. This production centre is actually in Borehamwood. The local newspaper is the ''Borehamwood and Elstree Times''. Together with Borehamwood, the village is twinned with Offenburg in Germany, Fontenay-aux-Roses in France, and Huainan in China. Transport Elstree and Borehamwood railway station Elstree & Borehamw ...
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Chelsea, London
Chelsea is an affluent area in west London, England, due south-west of Charing Cross by approximately 2.5 miles. It lies on the north bank of the River Thames and for postal purposes is part of the south-western postal area. Chelsea historically formed a manor and parish in the Ossulstone hundred of Middlesex, which became the Metropolitan Borough of Chelsea in 1900. It merged with the Metropolitan Borough of Kensington, forming the Royal Borough of Kensington and Chelsea upon the creation of Greater London in 1965. The exclusivity of Chelsea as a result of its high property prices historically resulted in the coining of the term "Sloane Ranger" in the 1970s to describe some of its residents, and some of those of nearby areas. Chelsea is home to one of the largest communities of Americans living outside the United States, with 6.53% of Chelsea residents having been born in the U.S. History Early history The word ''Chelsea'' (also formerly ''Chelceth'', ''Chelchith' ...
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Gale (publisher)
Gale is a global provider of research and digital learning resources. The company is based in Farmington Hills, Michigan, west of Detroit. It has been a division of Cengage since 2007. The company, formerly known as Gale Research and the Gale Group, is active in research and educational publishing for public, academic, and school libraries, and businesses. The company is known for its full-text magazine and newspaper databases, Gale OneFile (formerly known as Infotrac), and other online databases subscribed by libraries, as well as multi-volume reference works, especially in the areas of religion, history, and social science. Founded in Detroit, Michigan, in 1954 by Frederick Gale Ruffner Jr., the company was acquired by the International Thomson Organization (later the Thomson Corporation) in 1985 before its 2007 sale to Cengage. History In 1998, Gale Research merged with Information Access Company and Primary Source Media, two companies also owned by Thomson, to form ...
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John Charles Grant Ledingham
Sir John Charles Grant Ledingham Fellow of the Royal Society, FRS (19 May 1875 – 4 October 1944) was a British pathologist and bacteriologist. Ledinham was born at Boyndie (Banffshire, Banff) where James Ledingham, his father, was the local church minister. After education at Banff Academy he attended the University of Aberdeen, graduating M.A. (1895), B.Sc. (1900) and M.B., B.Chir. (1902). He had post-graduate training at the University of Leipzig in 1902–1903 and then did research at the bacteriological laboratories at the University of Aberdeen in 1903–1904 and at the Royal London Hospital, London Hospital in 1904–1905. At the Lister Institute of Preventive Medicine, Lister Institute he worked for a few months in the serum department at Lister Institute of Preventive Medicine#Elstree, Elstree but was then transferred to the main institute on Chelsea Embankment. At the Lister Institute he was an assistant bacteriologist from 1905–1908 and the chief bacteriologist f ...
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