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Nardi Test
The Nardi test, also known as the morphine-neostigmine provocation test is a test for dysfunction of the sphincter of Oddi, a valve which divides the biliary tract from the duodenum. Two medications, morphine and neostigmine, are given to people with symptoms concerning for sphincter dysfunction, including sharp right-sided abdominal pain Abdominal pain, also known as a stomach ache, is a symptom Signs and symptoms are the observed or detectable signs, and experienced symptoms of an illness, injury, or condition. A sign for example may be a higher or lower temperature than .... If the pain is reproduced by the medications, then dysfunction is more likely. The test poorly predicts dysfunction, however, and is rarely used today. The Nardi test was named for George Nardi, who first described the procedure in 1966. References *Nardi GL, Acosta JM.''Papillitis as a cause of pancreatitis and abdominal pain: role of evocative test, operative pancreatography and histologic evalu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sphincter Of Oddi
The sphincter of Oddi (also hepatopancreatic sphincter or Glisson's sphincter), abbreviated as SO, is a muscular valve that in some animals, including humans, controls the flow of digestive juices (bile and pancreatic juice) out of the pancreas through the ampulla of Vater into the second part of the duodenum. It is named after Ruggero Oddi. Structure The sphincter of Oddi is a circular muscle band (Sphincter) that surrounds the major duodenal papilla. Function The sphincter regulates the secretion of pancreatic juice and bile into the duodenum. It also prevents reflux of duodenal contents into the ampulla of Vater. The sphincter of Oddi is relaxed by the hormone cholecystokinin via vasoactive intestinal peptide. Clinical significance Opiates may cause spasms of the sphincter of Oddi, leading to increased serum amylase levels. History The sphincter was described for the first time by Ruggero Oddi when he was a young student in 1887. This description followed extensive r ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |