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NantOmics
NantOmics is a biotechnology company based in Culver City, California, which provides molecular diagnostic products for personalized cancer treatment. It is part of the NantWorks network, a corporation consisting of different startups in the medical and health industry. History NantOmics was founded in 2013 by billionaire Patrick Soon-Shiong. In 2015 NantOmics bought the cancer diagnostics company OncoPlex Dx. In 2017 the company acquired the consumer genomics startup Genos. In 2016 the company's revenue was about $58.3 million with a net loss of about $72.00 million. As of 2017, the company is classified as a unicorn startup with an estimated value of over $1 billion. NantHealth, Inc. held a 13.6% minority interest in the company at the end of 2021. Products GPS Cancer involves sequencing of the genome and RNA Ribonucleic acid (RNA) is a polymeric molecule essential in various biological roles in coding, decoding, regulation and expression of genes. RNA and deoxyrib ...
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Patrick Soon-Shiong
Patrick Soon-Shiong (born July 29, 1952) is a Chinese-South African transplant surgeon, billionaire businessman, bioscientist, and media proprietor. He is the inventor of the drug Abraxane, which became known for its efficacy against lung, breast, and pancreatic cancer. Soon-Shiong is the founder of NantWorks, a network of healthcare, biotech, and artificial intelligence startups; an adjunct professor of surgery and executive director of the Wireless Health Institute at the University of California, Los Angeles; and a visiting professor at Imperial College London and Dartmouth College.Biographies providing these details include , , and Soon-Shiong has published more than 100 scientific papers and has more than 230 issued patents worldwide on advancements spanning numerous fields in technology and medicine. Soon-Shiong is the chairman of three nonprofit organizations: the Chan Soon-Shiong Family Foundation, which aims to fund research and erase disparities in access to health c ...
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NantWorks
NantWorks LLC founded in 2007 is an American multinational conglomerate holding company. It owns a number of technology companies in the fields of healthcare, commerce, digital entertainment as well as a venture capital firm in the healthcare, education, science, and technology sectors. Particular technologies include machine vision, object and voice recognition, low power semiconductors, supercomputing, and networking technologies. The Chairman, CEO and founder of NantWorks is South African born physician Patrick Soon-Shiong. The constituent companies of the NantWorks Group are: *NantHealth **NantCloud (est. 2010, acquired by NantHealth in 2015, healthcare cloud computing) *NantOmics *NantBioScience *NantCell *NantKwest Inc. (immunotherapy for treatment of cancers, infectious, and inflammatory diseases) *NantPharma (also: Nant Pharma) LLC (est. 2012 with investments from Blackstone, manufactures and markets crude heparin, biologically derived pharmaceuticals including criti ...
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Limited Liability Company
A limited liability company (LLC for short) is the US-specific form of a private limited company. It is a business structure that can combine the pass-through taxation of a partnership or sole proprietorship with the limited liability of a corporation. An LLC is not a corporation under state law; it is a legal form of a company that provides limited liability to its owners in many jurisdictions. LLCs are well known for the flexibility that they provide to business owners; depending on the situation, an LLC may elect to use corporate tax rules instead of being treated as a partnership, and, under certain circumstances, LLCs may be organized as not-for-profit. In certain U.S. states (for example, Texas), businesses that provide professional services requiring a state professional license, such as legal or medical services, may not be allowed to form an LLC but may be required to form a similar entity called a professional limited liability company (PLLC). An LLC is a hybrid le ...
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Net Operating Loss
Under U.S. Federal income tax law, a net operating loss (NOL) occurs when certain tax-deductible expenses exceed taxable revenues for a taxable year. If a taxpayer is taxed during profitable periods without receiving any tax relief (e.g., a refund) during periods of NOLs, an unbalanced tax burden results. Consequently, in some situations, Congress allows taxpayers to use the losses in one year to offset the profits of other years. Calculating the NOL amount The NOL amount is the amount of the loss from the current year that can be carried forward to future years or, in certain instances, carried back to prior years. Individuals For individuals, the NOL amount is generally the excess of deductions over income from the operation of a business. The following items are excluded when calculating the NOL amount: * net capital losses, i.e., capital losses in excess of capital gains; (net capital gains are included) * nonbusiness deductions in excess of nonbusiness income; (net nonbusine ...
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Biotechnology Companies Established In 2013
Biotechnology is the integration of natural sciences and engineering sciences in order to achieve the application of organisms, cells, parts thereof and molecular analogues for products and services. The term ''biotechnology'' was first used by Károly Ereky in 1919, meaning the production of products from raw materials with the aid of living organisms. Definition The concept of biotechnology encompasses a wide range of procedures for modifying living organisms according to human purposes, going back to domestication of animals, cultivation of the plants, and "improvements" to these through breeding programs that employ artificial selection and hybridization. Modern usage also includes genetic engineering as well as cell and tissue culture technologies. The American Chemical Society defines biotechnology as the application of biological organisms, systems, or processes by various industries to learning about the science of life and the improvement of the value of materials and ...
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Biotechnology Companies Of The United States
Biotechnology is the integration of natural sciences and engineering sciences in order to achieve the application of organisms, cells, parts thereof and molecular analogues for products and services. The term ''biotechnology'' was first used by Károly Ereky in 1919, meaning the production of products from raw materials with the aid of living organisms. Definition The concept of biotechnology encompasses a wide range of procedures for modifying living organisms according to human purposes, going back to domestication of animals, cultivation of the plants, and "improvements" to these through breeding programs that employ artificial selection and hybridization. Modern usage also includes genetic engineering as well as cell and tissue culture technologies. The American Chemical Society defines biotechnology as the application of biological organisms, systems, or processes by various industries to learning about the science of life and the improvement of the value of materials ...
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Personalized Medicine
Personalized medicine, also referred to as precision medicine, is a medical model that separates people into different groups—with medical decisions, practices, interventions and/or products being tailored to the individual patient based on their predicted response or risk of disease. The terms personalized medicine, precision medicine, stratified medicine and P4 medicine are used interchangeably to describe this concept though some authors and organisations use these expressions separately to indicate particular nuances. While the tailoring of treatment to patients dates back at least to the time of Hippocrates, the term has risen in usage in recent years given the growth of new diagnostic and informatics approaches that provide understanding of the molecular basis of disease, particularly genomics. This provides a clear evidence base on which to stratify (group) related patients. Among the 14 Grand Challenges for Engineering, an initiative sponsored by National Academy of En ...
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Genome
In the fields of molecular biology and genetics, a genome is all the genetic information of an organism. It consists of nucleotide sequences of DNA (or RNA in RNA viruses). The nuclear genome includes protein-coding genes and non-coding genes, other functional regions of the genome such as regulatory sequences (see non-coding DNA), and often a substantial fraction of 'junk' DNA with no evident function. Almost all eukaryotes have mitochondria and a small mitochondrial genome. Algae and plants also contain chloroplasts with a chloroplast genome. The study of the genome is called genomics. The genomes of many organisms have been sequenced and various regions have been annotated. The International Human Genome Project reported the sequence of the genome for ''Homo sapiens'' in 200The Human Genome Project although the initial "finished" sequence was missing 8% of the genome consisting mostly of repetitive sequences. With advancements in technology that could handle sequenci ...
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NantHealth
NantHealth is one of the constituent companies of NantWorks, which is controlled by Patrick Soon-Shiong. With headquarters in Morrisville, North Carolina, Morrisville, North Carolina, the firm is focused on developing and marketing a range of healthcare solutions. In addition to Soon-Shiong, notable investors include Allscripts, BlackBerry, Kuwait Investment Authority, Celgene, and Verizon. In September 2014, NantHealth was featured as the cover story on Forbes Magazine, where it was estimated that NantHealth has a market value of $1.6 billion. In December 2014, NantHealth was featured on ''60 Minutes'' by Sanjay Gupta. In August 2017, NantHealth signed a distribution agreement for GPS Cancer with Asia Genomics. In January 2019, NantHealth received a delisting warning from NASDAQ, Nasdaq "because the Company’s common stock failed to maintain a minimum closing bid price of $1.00 for 30 consecutive business days." At the time, the market value of the company was approxima ...
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Unicorn (finance)
In business, a unicorn is a privately held startup company valued at over US$1 billion. The term was first published in 2013, coined by venture capitalist Aileen Lee, choosing the mythical animal to represent the statistical rarity of such successful ventures. CB Insights identified 1,170 unicorns worldwide . Unicorns with over $10 billion in valuation have been designated as "decacorn" companies. For private companies valued over $100 billion, the terms "centicorn", "hectocorn", and "super-unicorn" have been used. The term "kilocorn" has been used for companies valued at $1 trillion, of which Apple was the first. History Aileen Lee originated the term "unicorn" in a 2013 ''TechCrunch'' article, "Welcome To The Unicorn Club: Learning from Billion-Dollar Startups". At the time, 39 companies were identified as unicorns. In a different study done by ''Harvard Business Review'', it was determined that startups founded between 2012 and 2015 were growing in valuation twice as f ...
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Startup Company
A startup or start-up is a company or project undertaken by an entrepreneur to seek, develop, and validate a scalable business model. While entrepreneurship refers to all new businesses, including self-employment and businesses that never intend to become registered, startups refer to new businesses that intend to grow large beyond the solo founder. At the beginning, startups face high uncertainty and have high rates of failure, but a minority of them do go on to be successful and influential.Erin Griffith (2014)Why startups fail, according to their founders Fortune.com, 25 September 2014; accessed 27 October 2017 Actions Startups typically begin by a founder (solo-founder) or co-founders who have a way to solve a problem. The founder of a startup will begin market validation by problem interview, solution interview, and building a minimum viable product (MVP), i.e. a prototype, to develop and validate their business models. The startup process can take a long period of time (by so ...
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Revenue
In accounting, revenue is the total amount of income generated by the sale of goods and services related to the primary operations of the business. Commercial revenue may also be referred to as sales or as turnover. Some companies receive revenue from interest, royalties, or other fees A fee is the price one pays as remuneration for rights or services. Fees usually allow for overhead (business), overhead, wages, costs, and Profit (accounting), markup. Traditionally, professionals in the United Kingdom (and previously the Repu .... This definition is based on International Accounting Standard, IAS 18. "Revenue" may refer to income in general, or it may refer to the amount, in a monetary unit, earned during a period of time, as in "Last year, Company X had revenue of $42 million". Profit (accounting), Profits or net income generally imply total revenue minus total expenses in a given period. In accountancy, accounting, in the balance statement, revenue is a subsection of the ...
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