NMR Shift
Nuclear magnetic resonance spectroscopy, most commonly known as NMR spectroscopy or magnetic resonance spectroscopy (MRS), is a spectroscopic technique to observe local magnetic fields around atomic nuclei. The sample is placed in a magnetic field and the NMR signal is produced by excitation of the nuclei sample with radio waves into nuclear magnetic resonance, which is detected with sensitive radio receivers. The intramolecular magnetic field around an atom in a molecule changes the resonance frequency, thus giving access to details of the electronic structure of a molecule and its individual functional groups. As the fields are unique or highly characteristic to individual compounds, in modern organic chemistry practice, NMR spectroscopy is the definitive method to identify monomolecular organic compounds. The principle of NMR usually involves three sequential steps: # The alignment (polarization) of the magnetic nuclear spins in an applied, constant magnetic field B0. # The ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Nuclear Overhauser Effect
The nuclear Overhauser effect (NOE) is the transfer of nuclear spin polarization from one population of spin-active nuclei (e.g. 1H, 13C, 15N etc.) to another via cross-relaxation. A phenomenological definition of the NOE in nuclear magnetic resonance spectroscopy (NMR) is the change in the integrated intensity (positive or negative) of one NMR resonance that occurs when another is saturated by irradiation with an RF field. The change in resonance intensity of a nucleus is a consequence of the nucleus being close in space to those directly affected by the RF perturbation. The NOE is particularly important in the assignment of NMR resonances, and the elucidation and confirmation of the structures or configurations of organic and biological molecules. The 1H two-dimensional NOE SpectroscopY (NOESY) experiment and its extensions are important tools to identify stereochemistry of proteins and other biomolecules in solution, whereas in solid form crystal x-ray diffraction typicall ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Electromagnetic Radiation
In physics, electromagnetic radiation (EMR) consists of waves of the electromagnetic field, electromagnetic (EM) field, which propagate through space and carry momentum and electromagnetic radiant energy. It includes radio waves, microwaves, infrared, Light, (visible) light, ultraviolet, X-rays, and gamma rays. All of these waves form part of the electromagnetic spectrum. Classical electromagnetism, Classically, electromagnetic radiation consists of electromagnetic waves, which are synchronized oscillations of electric field, electric and magnetic fields. Depending on the frequency of oscillation, different wavelengths of electromagnetic spectrum are produced. In a vacuum, electromagnetic waves travel at the speed of light, commonly denoted ''c''. In homogeneous, isotropic media, the oscillations of the two fields are perpendicular to each other and perpendicular to the direction of energy and wave propagation, forming a transverse wave. The position of an electromagnetic wave w ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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NMR Sample
Nuclear magnetic resonance (NMR) is a physical phenomenon in which nuclei in a strong constant magnetic field are perturbed by a weak oscillating magnetic field (in the near field) and respond by producing an electromagnetic signal with a frequency characteristic of the magnetic field at the nucleus. This process occurs near resonance, when the oscillation frequency matches the intrinsic frequency of the nuclei, which depends on the strength of the static magnetic field, the chemical environment, and the magnetic properties of the isotope involved; in practical applications with static magnetic fields up to ca. 20 tesla, the frequency is similar to VHF and UHF television broadcasts (60–1000 MHz). NMR results from specific magnetic properties of certain atomic nuclei. Nuclear magnetic resonance spectroscopy is widely used to determine the structure of organic molecules in solution and study molecular physics and crystals as well as non-crystalline materials. NM ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Nobel Prize In Physics
) , image = Nobel Prize.png , alt = A golden medallion with an embossed image of a bearded man facing left in profile. To the left of the man is the text "ALFR•" then "NOBEL", and on the right, the text (smaller) "NAT•" then "MDCCCXXXIII" above, followed by (smaller) "OB•" then "MDCCCXCVI" below. , awarded_for = Outstanding contributions for humankind in the field of Physics , presenter = Royal Swedish Academy of Sciences , location = Stockholm, Sweden , date = , reward = 9 million Swedish kronor (2017) , year = 1901 , holder_label = Most recently awarded to , holder = Alain Aspect, John Clauser, and Anton Zeilinger , most_awards = John Bardeen (2) , website nobelprize.org, previous = 2021 , year2=2022, main=2022, next=2023 The Nobel Prize in Physics is a yearly award given by the Royal Swedish Academy of Sciences for those who have made the most outstanding contributions for humankind in the field of physics. It ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Felix Bloch
Felix Bloch (23 October 1905 – 10 September 1983) was a Swiss-American physicist and Nobel physics laureate who worked mainly in the U.S. He and Edward Mills Purcell were awarded the 1952 Nobel Prize for Physics for "their development of new ways and methods for nuclear magnetic precision measurements."Sohlman, M (Ed.) ''Nobel Foundation directory 2003.'' Vastervik, Sweden: AB CO Ekblad; 2003. In 1954–1955, he served for one year as the first Director-General of CERN. Felix Bloch made fundamental theoretical contributions to the understanding of ferromagnetism and electron behavior in crystal lattices. He is also considered one of the developers of nuclear magnetic resonance. Biography Early life, education, and family Bloch was born in Zürich, Switzerland to Jewish parents Gustav and Agnes Bloch. Gustav Bloch, his father, was financially unable to attend University and worked as a wholesale grain dealer in Zürich. Gustav moved to Zürich in 1890 to become a Swiss c ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Edward Mills Purcell
Edward Mills Purcell (August 30, 1912 – March 7, 1997) was an American physicist who shared the 1952 Nobel Prize for Physics for his independent discovery (published 1946) of nuclear magnetic resonance in liquids and in solids. Nuclear magnetic resonance (NMR) has become widely used to study the molecular structure of pure materials and the composition of mixtures. Friends and colleagues knew him as Ed Purcell. Biography Born and raised in Taylorville, Illinois, Purcell received his BSEE in electrical engineering from Purdue University, followed by his M.A. and Ph.D. in physics from Harvard University. He was a member of the Alpha Xi chapter of the Phi Kappa Sigma fraternity while at Purdue. After spending the years of World War II working at the MIT Radiation Laboratory on the development of microwave radar, Purcell returned to Harvard to do research. In December 1946, he discovered nuclear magnetic resonance (NMR) with his colleagues Robert Pound and Henry Torrey. NMR p ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Stanford University
Stanford University, officially Leland Stanford Junior University, is a private research university in Stanford, California. The campus occupies , among the largest in the United States, and enrolls over 17,000 students. Stanford is considered among the most prestigious universities in the world. Stanford was founded in 1885 by Leland and Jane Stanford in memory of their only child, Leland Stanford Jr., who had died of typhoid fever at age 15 the previous year. Leland Stanford was a U.S. senator and former governor of California who made his fortune as a railroad tycoon. The school admitted its first students on October 1, 1891, as a coeducational and non-denominational institution. Stanford University struggled financially after the death of Leland Stanford in 1893 and again after much of the campus was damaged by the 1906 San Francisco earthquake. Following World War II, provost of Stanford Frederick Terman inspired and supported faculty and graduates' entrepreneu ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Harvard University
Harvard University is a private Ivy League research university in Cambridge, Massachusetts. Founded in 1636 as Harvard College and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of higher learning in the United States and one of the most prestigious and highly ranked universities in the world. The university is composed of ten academic faculties plus Harvard Radcliffe Institute. The Faculty of Arts and Sciences offers study in a wide range of undergraduate and graduate academic disciplines, and other faculties offer only graduate degrees, including professional degrees. Harvard has three main campuses: the Cambridge campus centered on Harvard Yard; an adjoining campus immediately across Charles River in the Allston neighborhood of Boston; and the medical campus in Boston's Longwood Medical Area. Harvard's endowment is valued at $50.9 billion, making it the wealthiest academic institution in the world. Endowment inco ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Isidor Isaac Rabi
Isidor Isaac Rabi (; born Israel Isaac Rabi, July 29, 1898 – January 11, 1988) was an American physicist who won the Nobel Prize in Physics in 1944 for his discovery of nuclear magnetic resonance, which is used in magnetic resonance imaging. He was also one of the first scientists in the United States to work on the cavity magnetron, which is used in microwave radar and microwave ovens. Born into a traditional Polish-Jewish family in Rymanów, Galicia, Rabi came to the United States as an infant and was raised in New York's Lower East Side. He entered Cornell University as an electrical engineering student in 1916, but soon switched to chemistry. Later, he became interested in physics. He continued his studies at Columbia University, where he was awarded his doctorate for a thesis on the magnetic susceptibility of certain crystals. In 1927, he headed for Europe, where he met and worked with many of the finest physicists of the time. In 1929, Rabi returned to the ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Benchtop Nuclear Magnetic Resonance Spectrometer
A Benchtop nuclear magnetic resonance spectrometer (Benchtop NMR spectrometer) refers to a Fourier transform nuclear magnetic resonance (FT-NMR) spectrometer that is significantly more compact and portable than the conventional equivalents, such that it is portable and can reside on a laboratory benchtop. This convenience comes from using permanent magnets, which have a lower magnetic field and decreased sensitivity compared to the much larger and more expensive cryogen cooled superconducting NMR magnets. Instead of requiring dedicated infrastructure, rooms and extensive installations these benchtop instruments can be placed directly on the bench in a lab and moved as necessary (''e.g.,'' to the fumehood). These spectrometers offer improved workflow, even for novice users, as they are simpler and easy to use. They differ from relaxometers in that they can be used to measure high resolution NMR spectra and are not limited to the determination of relaxation or diffusion parameters ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Superconducting
Superconductivity is a set of physical properties observed in certain materials where Electrical resistance and conductance, electrical resistance vanishes and magnetic field, magnetic flux fields are expelled from the material. Any material exhibiting these properties is a superconductor. Unlike an ordinary metallic electrical conductor, conductor, whose resistance decreases gradually as its temperature is lowered even down to near absolute zero, a superconductor has a characteristic Phase transition, critical temperature below which the resistance drops abruptly to zero. An electric current through a loop of superconducting wire can persist indefinitely with no power source. The superconductivity phenomenon was discovered in 1911 by Dutch physicist Heike Kamerlingh Onnes. Like ferromagnetism and atomic spectral lines, superconductivity is a phenomenon which can only be explained by quantum mechanics. It is characterized by the Meissner effect, the complete ejection of magne ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |