|
N-Methyltryptamine
''N''-Methyltryptamine (NMT) is a member of the substituted tryptamine chemical class and a natural product which is biosynthesized in the human body from tryptamine by certain N-methyltransferase enzymes, such as indolethylamine ''N''-methyltransferase. It is a common component in human urine. NMT is an alkaloid derived from L-tryptophan that has been found in the bark, shoots and leaves of several plant genera, including ''Virola'', ''Acacia'', ''Mimosa'', and ''Desmanthus''—often together with the related compounds ''N'',''N''-dimethyltryptamine (DMT) and 5-methoxy-''N'',''N''-dimethyltryptamine (5-MeO-DMT). Orally administered NMT appears to produce no psychoactive effects, likely as a result of extensive first-pass metabolism.Foye's principles of medicinal chemistry By William O. Foye, Thomas L. Lemke, David A. Williams However, it may become active upon combination with a MAOA inhibitor (MAOI). By vaporization NMT shows activity at 50–100 mg, with a duration o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Acacia Confusa
''Acacia confusa'' is a perennial tree native to South-East Asia. Some common names for it are acacia petit feuille, Ayangile, small Philippine acacia, Formosa acacia (Taiwan acacia), Philippine Wattle, and Formosan koa. It grows to a height of 15 m. The tree has become very common in many tropical Pacific areas, including Hawaii, where the species is considered invasive. Uses The wood has a density of about 0.75 g/cm3. In Taiwan, its wood was used to make support beams for underground mines. Acacia confusa is challenging to work and for this reason was traditionally burned as firewood or turned into charcoal in Taiwan. In later years it was exported to China to be made into wood flooring for the American market. At its height Taiwan exported more than 1,000 containers of Taiwan acacia to China. More recently it has been used domestically to produce high value wood products like musical instruments, furniture, and bathtubs. The wood is also converted to charcoal for family use. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Substituted Tryptamine
Substituted tryptamines, or serotonin analogues, are organic compounds which may be thought of as being derived from tryptamine itself. The molecular structures of all tryptamines contain an indole ring, joined to an amino group, amino (NH2) group via an ethyl (−CH2–CH2−) side chain, sidechain. In substituted tryptamines, the indole ring, sidechain, and/or amino group are modified by substituting another group for one of the hydrogen (H) atoms. Well-known tryptamines include serotonin, an important neurotransmitter, and melatonin, a hormone involved in regulating the sleep-wake cycle. Tryptamine alkaloids are found in fungi, plants and animals; and sometimes used by humans for the neurological or psychotropic effects of the substance. Prominent examples of tryptamine alkaloids include psilocybin (from "psilocybin mushrooms") and dimethyltryptamine, DMT. In South America, dimethyltryptamine is obtained from numerous plant sources, like chacruna, and it is often used in ayahuas ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Desmanthus
''Desmanthus'' is a genus of flowering plants in the mimosoid clade of the subfamily Caesalpinioideae of the pea family, Fabaceae. The name is derived from the Greek words δεσμός (''desmos''), meaning "bundle", and ἄνθος (''anthos''), meaning "flower". It contains about 24 species of herbs and shrubs that are sometimes described as being suffruiticose and have bipinnate leaves. ''Desmanthus'' is closely related to ''Leucaena'' and in appearance is similar to '' Neptunia''. Like ''Mimosa'' and ''Neptunia'', ''Desmanthus'' species fold their leaves in the evening. They are native to Mexico and North, Central and South America. Members of the genus are commonly known as bundleflowers. Donkey beans is another common name and originated in Central America, where ''Desmanthus'' species are highly regarded as fodder for these domestic draught animals. Description There are considerable differences in the descriptions of ''Desmanthus'' in the literature ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
N-Ethyltryptamine
''N''-Ethyltryptamine (NET), or merely ethyltryptamine, is a tryptamine that is structurally related to ''N''-methyltryptamine (NMT) and the psychedelic drug Psychedelics are a subclass of hallucinogenic drugs whose primary effect is to trigger non-ordinary states of consciousness (known as psychedelic experiences or "trips").Pollan, Michael (2018). ''How to Change Your Mind: What the New Science o ...s ''N'',''N''-dimethyltryptamine (DMT) and ''N'',''N''-diethyltryptamine (DET). See also * ''N''-Methyltryptamine (NMT) * ''N'',''N'',-Dimethyltryptamine (DMT) References {{DEFAULTSORT:Ethyltryptamine, N- Tryptamines Serotonin receptor agonists ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Desmanthus Illinoensis
''Desmanthus illinoensis'', commonly known as Illinois bundleflower, prairie-mimosa or prickleweed, is a common plant in many areas of the south central and Midwestern US. Habitat It can often be found growing on the sides of roads, needing full sun and ample moisture during its short growing season. USDA Zones 5-8 are recommended for outside cultivation. Chemistry Root bark of ''D. illinoensis'' has been found to contain N,N-DMT, NMT, N-hydroxy-N-methyltryptamine, 2-hydroxy-N-methyltryptamine, and gramine (toxic). Nutritional benefits The plant is nutritious and high in protein. The Land Institute in Salina, Kansas has done extensive research into the food uses of the seeds of this plant. Studies found the dry seeds composed of 38% protein, compared to 40% for soybeans. Ayahuasca analogue The root bark is mixed with a native source of beta-Carbolines (e.g., passion flower in North America) to produce a hallucinogenic plant concoction analogous to the shamanic Sou ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
N-methyltransferase
N-methyltransferase may refer to: *(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline N-methyltransferase * 3-hydroxy-16-methoxy-2,3-dihydrotabersonine N-methyltransferase * Amine N-methyltransferase * Anthranilate N-methyltransferase * (cytochrome c)-arginine N-methyltransferase * (myelin basic protein)-arginine N-methyltransferase * Calmodulin-lysine N-methyltransferase *Carnosine N-methyltransferase * (S)-coclaurine-N-methyltransferase * Dimethylhistidine N-methyltransferase *Glycine N-methyltransferase *Guanidinoacetate N-methyltransferase *Histamine N-methyltransferase *Histone methyltransferase * (cytochrome c)-lysine N-methyltransferase *(ribulose-bisphosphate carboxylase)-lysine N-methyltransferase *Methylamine—glutamate N-methyltransferase * Nicotinamide N-methyltransferase *Nicotinate N-methyltransferase *Phenylethanolamine N-methyltransferase *Phosphatidylethanolamine N-methyltransferase *Phosphatidyl-N-methylethanolamine N-methyltransferase *Phosphoethanolamine N-methyltransf ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
N,N-dimethyltryptamine
''N'',''N''-Dimethyltryptamine (DMT or ''N'',''N''-DMT, SPL026) is a substituted tryptamine that occurs in many plants and animals, including human beings, and which is both a derivative and a structural analog of tryptamine. It is used as a psychedelic drug and prepared by various cultures for ritual purposes as an entheogen. DMT has a rapid onset, intense effects, and a relatively short duration of action. For those reasons, DMT was known as the "business trip" during the 1960s in the United States, as a user could access the full depth of a psychedelic experience in considerably less time than with other substances such as LSD or psilocybin mushrooms. DMT can be inhaled, ingested, or injected and its effects depend on the dose, as well as the mode of administration. When inhaled or injected, the effects last a short period of time: about five to 15 minutes. Effects can last three hours or more when orally ingested along with a monoamine oxidase inhibitor (MAOI), such as t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Acacia Simplicifolia
''Acacia simplex'' is a perennial climbing tree native to islands in the western part of the Pacific Ocean as far east as Savaii. It is also found in Argentina. This tree grows up to 12 m in height. There is no common English name, but it is called ''tatakia'' in Fiji, ''tatagia'' in Samoa, ''tātāngia'' in Tonga and ''Martaoui'' in New-Caledonia Uses The tree is used as a toxin in fishing. It incapacitates the fish, but it is apparently not harmful to people. Phytochemicals Bark * ''N''-methyltryptamine * ''N'',''N''-dimethyltryptamine * 2-methyl-1,2,3,4-tetrahydro-β-carboline Leafy stems *N-methyltryptamine *N,N-dimethyltryptamine *2-methyl-1,2,3,4-tetrahydro-β-carboline * ''N'',''N''-formylmethyltryptamine *Traces of another unidentified alkaloid Stem bark Total alkaloids 3.6% of which 40% N-methyltryptamine, 22.5% N,N-dimethyltryptamine, 12.7% 2-methyl-1,2,3,4-tetrahydro-β-carboline. Twigs Total alkaloids 0.11%, of which ''N''-methyltryptamine is 26.3%, 6.2% ''N' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Acacia Obtusifolia
''Acacia obtusifolia'', commonly known as stiff-leaf wattle or blunt-leaf wattle, is a perennial tree in subfamily Mimosoideae of family Fabaceae. Description ''Acacia obtusifolia'' is an upright or spreading perennial tree which grows from 1.5m to 8m in height and it is native to Australia. It is closely related to '' Acacia longifolia''. ''Acacia obtusifolia'' can be distinguished by it having phyllode margins which are resinous, it usually blooms later in the year and it has paler flowers than ''Acacia longifolia.'' It flowers usually from December through February. Some populations of ''Acacia obtusifolia'' can survive winters to −6 °C and possibly a light snow, however plants from populations in areas that are frost free such as the coastal ranges of Northern NSW are susceptible to cold and will be killed by frosts lower than −3 °C. These populations avoid the valley floors and occur mainly on sandstone ridges well above the frost line. Phytochemicals ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Natural Product
A natural product is a natural compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life. Natural products can also be prepared by chemical synthesis (both semisynthesis and total synthesis) and have played a central role in the development of the field of organic chemistry by providing challenging synthetic targets. The term natural product has also been extended for commercial purposes to refer to cosmetics, dietary supplements, and foods produced from natural sources without added artificial ingredients. Within the field of organic chemistry, the definition of natural products is usually restricted to organic compounds isolated from natural sources that are produced by the pathways of primary or secondary metabolism. Within the field of medicinal chemistry, the definition is often further restricted to secondary metabolites. Secondary metabolites (or specialized metabolites ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
N,N-Dimethyltryptamine
''N'',''N''-Dimethyltryptamine (DMT or ''N'',''N''-DMT, SPL026) is a substituted tryptamine that occurs in many plants and animals, including human beings, and which is both a derivative and a structural analog of tryptamine. It is used as a psychedelic drug and prepared by various cultures for ritual purposes as an entheogen. DMT has a rapid onset, intense effects, and a relatively short duration of action. For those reasons, DMT was known as the "business trip" during the 1960s in the United States, as a user could access the full depth of a psychedelic experience in considerably less time than with other substances such as LSD or psilocybin mushrooms. DMT can be inhaled, ingested, or injected and its effects depend on the dose, as well as the mode of administration. When inhaled or injected, the effects last a short period of time: about five to 15 minutes. Effects can last three hours or more when orally ingested along with a monoamine oxidase inhibitor (MAOI), such as t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biosynthesized
Biosynthesis is a multi-step, enzyme-catalyzed process where substrates are converted into more complex products in living organisms. In biosynthesis, simple compounds are modified, converted into other compounds, or joined to form macromolecules. This process often consists of metabolic pathways. Some of these biosynthetic pathways are located within a single cellular organelle, while others involve enzymes that are located within multiple cellular organelles. Examples of these biosynthetic pathways include the production of lipid membrane components and nucleotides. Biosynthesis is usually synonymous with anabolism. The prerequisite elements for biosynthesis include: precursor compounds, chemical energy (e.g. ATP), and catalytic enzymes which may require coenzymes (e.g.NADH, NADPH). These elements create monomers, the building blocks for macromolecules. Some important biological macromolecules include: proteins, which are composed of amino acid monomers joined via peptide bonds ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
