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Multielectrode Array
Microelectrode arrays (MEAs) (also referred to as multielectrode arrays) are devices that contain multiple (tens to thousands) microelectrodes through which neural signals are obtained or delivered, essentially serving as neural interfaces that connect neurons to electronic circuitry. There are two general classes of MEAs: implantable MEAs, used '' in vivo'', and non-implantable MEAs, used '' in vitro''. Theory Neurons and muscle cells create ion currents through their membranes when excited, causing a change in voltage between the inside and the outside of the cell. When recording, the electrodes on an MEA transduce the change in voltage from the environment carried by ions into currents carried by electrons (electronic currents). When stimulating, electrodes transduce electronic currents into ionic currents through the media. This triggers the voltage-gated ion channels on the membranes of the excitable cells, causing the cell to depolarize and trigger an action potent ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Depolarization
In biology, depolarization or hypopolarization is a change within a cell, during which the cell undergoes a shift in electric charge distribution, resulting in less negative charge inside the cell compared to the outside. Depolarization is essential to the function of many cells, communication between cells, and the overall physiology of an organism. Most cells in higher organisms maintain an internal environment that is negatively charged relative to the cell's exterior. This difference in charge is called the cell's membrane potential. In the process of depolarization, the negative internal charge of the cell temporarily becomes more positive (less negative). This shift from a negative to a more positive membrane potential occurs during several processes, including an action potential. During an action potential, the depolarization is so large that the potential difference across the cell membrane briefly reverses polarity, with the inside of the cell becoming positively char ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Contact Pad
Contact pads or bond pads are designated surface areas of a printed circuit board (PCB) or die of an integrated circuit. Possibilities to contact to pads include soldering, wirebonding, flip chip Flip chip, also known as controlled collapse chip connection or its abbreviation, C4, is a method for interconnecting dies such as semiconductor devices, IC chips, integrated passive devices and microelectromechanical systems (MEMS), to exter ... mounting, or probe needles. Further reading *Kraig Mitzner, ''Complete PCB Design Using OrCAD Capture and PCB Editor'', Newnes, 2009 . *Jing Li, ''Evaluation and Improvement of the Robustness of a PCB Pad in a Lead-free Environment'', ProQuest, 2007 . *Deborah Lea, Fredirikus Jonck, Christopher Hunt, ''Solderability Measurements of PCB Pad Finishes and Geometries'', National Physical Laboratory, 2001 . Electronic engineering Printed circuit board manufacturing {{Electronics-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Digital Signal Processing
Digital signal processing (DSP) is the use of digital processing, such as by computers or more specialized digital signal processors, to perform a wide variety of signal processing operations. The digital signals processed in this manner are a sequence of numbers that represent samples of a continuous variable in a domain such as time, space, or frequency. In digital electronics, a digital signal is represented as a pulse train, which is typically generated by the switching of a transistor. Digital signal processing and analog signal processing are subfields of signal processing. DSP applications include audio and speech processing, sonar, radar and other sensor array processing, spectral density estimation, statistical signal processing, digital image processing, data compression, video coding, audio coding, image compression, signal processing for telecommunications, control systems, biomedical engineering, and seismology, among others. DSP can involve linear ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sampling Rate
In signal processing, sampling is the reduction of a continuous-time signal In mathematical dynamics, discrete time and continuous time are two alternative frameworks within which variables that evolve over time are modeled. Discrete time Discrete time views values of variables as occurring at distinct, separate "po ... to a discrete-time signal. A common example is the conversion of a sound wave to a sequence of "samples". A sample is a value of the signal at a point in time and/or space; this definition differs from the usage in statistics, which refers to a set of such values. A sampler is a subsystem or operation that extracts samples from a continuous signal. A theoretical ideal sampler produces samples equivalent to the instantaneous value of the continuous signal at the desired points. The original signal can be reconstructed from a sequence of samples, up to the Nyquist limit, by passing the sequence of samples through a type of low-pass filter called a recon ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sampling (signal Processing)
In signal processing, sampling is the reduction of a continuous-time signal to a discrete-time signal. A common example is the conversion of a sound wave to a sequence of "samples". A sample is a value of the signal at a point in time and/or space; this definition differs from the usage in statistics, which refers to a set of such values. A sampler is a subsystem or operation that extracts samples from a continuous signal. A theoretical ideal sampler produces samples equivalent to the instantaneous value of the continuous signal at the desired points. The original signal can be reconstructed from a sequence of samples, up to the Nyquist limit, by passing the sequence of samples through a type of low-pass filter called a reconstruction filter. Theory Functions of space, time, or any other dimension can be sampled, and similarly in two or more dimensions. For functions that vary with time, let ''S''(''t'') be a continuous function (or "signal") to be sampled, and let ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cutoff Frequency
In physics and electrical engineering, a cutoff frequency, corner frequency, or break frequency is a boundary in a system's frequency response at which energy flowing through the system begins to be reduced ( attenuated or reflected) rather than passing through. Typically in electronic systems such as filters and communication channels, cutoff frequency applies to an edge in a lowpass, highpass, bandpass, or band-stop characteristic – a frequency characterizing a boundary between a passband and a stopband. It is sometimes taken to be the point in the filter response where a transition band and passband meet, for example, as defined by a half-power point (a frequency for which the output of the circuit is −3 dB of the nominal passband value). Alternatively, a stopband corner frequency may be specified as a point where a transition band and a stopband meet: a frequency for which the attenuation is larger than the required stopband attenuation, which for example m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bandwidth (signal Processing)
Bandwidth is the difference between the upper and lower frequencies in a continuous band of frequencies. It is typically measured in hertz, and depending on context, may specifically refer to '' passband bandwidth'' or ''baseband bandwidth''. Passband bandwidth is the difference between the upper and lower cutoff frequencies of, for example, a band-pass filter, a communication channel, or a signal spectrum. Baseband bandwidth applies to a low-pass filter or baseband signal; the bandwidth is equal to its upper cutoff frequency. Bandwidth in hertz is a central concept in many fields, including electronics, information theory, digital communications, radio communications, signal processing, and spectroscopy and is one of the determinants of the capacity of a given communication channel. A key characteristic of bandwidth is that any band of a given width can carry the same amount of information, regardless of where that band is located in the frequency spectrum. For exa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gain (electronics)
In electronics, gain is a measure of the ability of a two-port circuit (often an amplifier) to increase the power or amplitude of a signal from the input to the output port by adding energy converted from some power supply to the signal. It is usually defined as the mean ratio of the signal amplitude or power at the output port to the amplitude or power at the input port. It is often expressed using the logarithmic decibel (dB) units ("dB gain"). A gain greater than one (greater than zero dB), that is amplification, is the defining property of an active component or circuit, while a passive circuit will have a gain of less than one. The term ''gain'' alone is ambiguous, and can refer to the ratio of output to input voltage (''voltage gain''), current (''current gain'') or electric power (''power gain''). In the field of audio and general purpose amplifiers, especially operational amplifiers, the term usually refers to voltage gain, but in radio frequency amplifiers ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Analog Signal Processing
Analog signal processing is a type of signal processing conducted on continuous analog signals by some analog means (as opposed to the discrete digital signal processing where the signal processing is carried out by a digital process). "Analog" indicates something that is mathematically represented as a set of continuous values. This differs from "digital" which uses a series of discrete quantities to represent signal. Analog values are typically represented as a voltage, electric current, or electric charge around components in the electronic devices. An error or noise affecting such physical quantities will result in a corresponding error in the signals represented by such physical quantities. Examples of ''analog signal processing'' include crossover filters in loudspeakers, "bass", "treble" and "volume" controls on stereos, and "tint" controls on TVs. Common analog processing elements include capacitors, resistors and inductors (as the passive elements) and transistors or opamps ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Electrical Impedance
In electrical engineering, impedance is the opposition to alternating current presented by the combined effect of resistance and reactance in a circuit. Quantitatively, the impedance of a two-terminal circuit element is the ratio of the complex representation of the sinusoidal voltage between its terminals, to the complex representation of the current flowing through it. In general, it depends upon the frequency of the sinusoidal voltage. Impedance extends the concept of resistance to alternating current (AC) circuits, and possesses both magnitude and phase, unlike resistance, which has only magnitude. Impedance can be represented as a complex number, with the same units as resistance, for which the SI unit is the ohm (). Its symbol is usually , and it may be represented by writing its magnitude and phase in the polar form . However, Cartesian complex number representation is often more powerful for circuit analysis purposes. The notion of impedance is useful fo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Homogeneous (chemistry)
In chemistry, a mixture is a material made up of two or more different chemical substances which are not chemically bonded. A mixture is the physical combination of two or more substances in which the identities are retained and are mixed in the form of solutions, suspensions and colloids. Mixtures are one product of mechanically blending or mixing chemical substances such as elements and compounds, without chemical bonding or other chemical change, so that each ingredient substance retains its own chemical properties and makeup. Despite the fact that there are no chemical changes to its constituents, the physical properties of a mixture, such as its melting point, may differ from those of the components. Some mixtures can be separated into their components by using physical (mechanical or thermal) means. Azeotropes are one kind of mixture that usually poses considerable difficulties regarding the separation processes required to obtain their constituents (physical or chemical ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
