Mueller–Weiss Syndrome
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Mueller–Weiss Syndrome
Mueller–Weiss syndrome, also known as Mueller–Weiss disease, is a rare idiopathic degenerative disease of the adult navicular bone characterized by progressive collapse and fragmentation, leading to mid- and hindfoot pain and deformity. It is most commonly seen in females, ages 40–60. Characteristic imaging shows lateral navicular collapse. This disease had been historically considered to be a form of adult onset osteonecrosis, with blood flow cutoff to the navicular. Navicular The Navicular bone, navicular, deriving its name from its boat–like shape, is a small but critical bone. It connects the ankle with the bones of the foot. It articulates with five tarsus (skeleton), tarsal bones (talus bone, talus, cuboid bone, cuboid, and three cuneiform bones) forming slightly mobile Fibrous joint#Syndesmosis, syndesmotic (fibrous) joints and has a significant function in maintaining the arch and the dynamic biomechanics of walking. The middle third of the bone lacks blood vess ...
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Orthopedics
Orthopedic surgery or orthopedics ( alternatively spelt orthopaedics), is the branch of surgery concerned with conditions involving the musculoskeletal system. Orthopedic surgeons use both surgical and nonsurgical means to treat musculoskeletal trauma, spine diseases, sports injuries, degenerative diseases, infections, tumors, and congenital disorders. Etymology Nicholas Andry coined the word in French as ', derived from the Ancient Greek words ὀρθός ''orthos'' ("correct", "straight") and παιδίον ''paidion'' ("child"), and published ''Orthopedie'' (translated as ''Orthopædia: Or the Art of Correcting and Preventing Deformities in Children'') in 1741. The word was assimilated into English as ''orthopædics''; the ligature ''æ'' was common in that era for ''ae'' in Greek- and Latin-based words. As the name implies, the discipline was initially developed with attention to children, but the correction of spinal and bone deformities in all stages of life eventually ...
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Blood Vessel
The blood vessels are the components of the circulatory system that transport blood throughout the human body. These vessels transport blood cells, nutrients, and oxygen to the tissues of the body. They also take waste and carbon dioxide away from the tissues. Blood vessels are needed to sustain life, because all of the body's tissues rely on their functionality. There are five types of blood vessels: the arteries, which carry the blood away from the heart; the arterioles; the capillaries, where the exchange of water and chemicals between the blood and the tissues occurs; the venules; and the veins, which carry blood from the capillaries back towards the heart. The word ''vascular'', meaning relating to the blood vessels, is derived from the Latin ''vas'', meaning vessel. Some structures – such as cartilage, the epithelium, and the lens and cornea of the eye – do not contain blood vessels and are labeled ''avascular''. Etymology * artery: late Middle English; from Latin ...
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Osteomyelitis
Osteomyelitis (OM) is an infection of bone. Symptoms may include pain in a specific bone with overlying redness, fever, and weakness. The long bones of the arms and legs are most commonly involved in children e.g. the femur and humerus, while the feet, spine, and hips are most commonly involved in adults. The cause is usually a bacterial infection, but rarely can be a fungal infection. It may occur by spread from the blood or from surrounding tissue. Risks for developing osteomyelitis include diabetes, intravenous drug use, prior removal of the spleen, and trauma to the area. Diagnosis is typically suspected based on symptoms and basic laboratory tests as C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR).This is because plain radiographs are unremarkable in the first few days following acute infection. Diagnosis is further confirmed by blood tests, medical imaging, or bone biopsy. Treatment of bacterial osteomyelitis often involves both antimicrobials and sur ...
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Paget's Disease Of Bone
Paget's disease of bone (commonly known as Paget's disease or, historically, osteitis deformans) is a condition involving cellular remodeling and deformity of one or more bones. The affected bones show signs of dysregulated bone remodeling at the microscopic level, specifically excessive bone breakdown and subsequent disorganized new bone formation. These structural changes cause the bone to weaken, which may result in deformity, pain, bone fractures, fracture or arthritis of associated joints. The exact cause is unknown, although leading theories indicate both genetic and acquired factors (see Paget's disease of bone#Causes, Causes). Paget's disease may affect any one or several bones of the body (most commonly pelvis, tibia, femur, lumbar vertebrae, and skull), but never the entire skeleton, and does not spread from bone to bone. Rarely, a bone affected by Paget's disease can transform into a Osteosarcoma, malignant bone cancer. As the disease often affects people differently, ...
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Foot
The foot ( : feet) is an anatomical structure found in many vertebrates. It is the terminal portion of a limb which bears weight and allows locomotion. In many animals with feet, the foot is a separate organ at the terminal part of the leg made up of one or more segments or bones, generally including claws or nails. Etymology The word "foot", in the sense of meaning the "terminal part of the leg of a vertebrate animal" comes from "Old English fot "foot," from Proto-Germanic *fot (source also of Old Frisian fot, Old Saxon fot, Old Norse fotr, Danish fod, Swedish fot, Dutch voet, Old High German fuoz, German Fuß, Gothic fotus "foot"), from PIE root *ped- "foot". The "plural form feet is an instance of i-mutation." Structure The human foot is a strong and complex mechanical structure containing 26 bones, 33 joints (20 of which are actively articulated), and more than a hundred muscles, tendons, and ligaments.Podiatry Channel, ''Anatomy of the foot and ankle'' The joints of the ...
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Pain Out Of Proportion
Pain out of proportion or pain out of proportion to physical examination is a medical sign where apparent pain in the individual does not correspond to other signs. It is found in a number of conditions, including: *Necrotizing fasciitis *Compartment syndrome *Mesenteric ischemia Intestinal ischemia is a medical condition in which injury to the large or small intestine occurs due to not enough blood supply. It can come on suddenly, known as acute intestinal ischemia, or gradually, known as chronic intestinal ischemia. The ... * Mueller-Weiss disease References Medical terminology {{med-sign-stub ...
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Valgus Deformity
A valgus deformity is a condition in which the bone segment distal Standard anatomical terms of location are used to unambiguously describe the anatomy of animals, including humans. The terms, typically derived from Latin or Greek roots, describe something in its standard anatomical position. This position pro ... to a joint is angled outward, that is, angled laterally, away from the body's midline. The opposite deformation, where the twist or angulation is directed medially, toward the center of the body, is called varus deformity, varus. Common causes of valgus knee (genu valgum or "knock-knee") in adults include arthritis of the knee and traumatic injuries. Knee arthritis with valgus knee Rheumatoid knee commonly presents as valgus knee. Osteoarthritis knee may also sometimes present with valgus deformity though varus deformity is common. Total knee arthroplasty (TKA) to correct valgus deformity is surgically difficult and requires specialized implants called Knee repl ...
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Varus Deformity
Varus may refer to: * Var River or Varus, a river in France * Stura di Lanzo or Varus, a river in Italy * Varus deformity, a medical term for the inward angulation of the distal segment of a bone or joint ** Coxa vara, affecting the hip ** Genu varum, affecting the knee ** Hallux varus, affecting the big toe ** Cubitus varus, affecting the elbow ** Club foot (talipes equinovarus), affecting the heel People with the name * Publius Attius Varus (died 45 BC), Roman governor of Africa * Publius Quinctilius Varus (46 BC–AD 9), politician and general of the Roman Empire * Publius Quinctilius Varus the Younger (c. AD 1–27), son of Publius Quinctilius Varus * Marcus Plancius Varus (1st century AD), politician of the Roman Empire * Gaius Plancius Varus (1st–2nd century AD), son of Marcus Plancius Varus and politician of the Roman Empire * Titus Clodius Vibius Varus, Roman consul, 160 AD * Titus Vibius Varus, Roman consul, 134 AD * Titus Vibius Varus, Roman suffect consul, 115 AD ...
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Flat Foot
Flat feet (also called pes planus or fallen arches) is a postural deformity in which the arches of the foot collapse, with the entire sole of the foot coming into complete or near-complete contact with the ground. Sometimes children are born with flat feet (congenital). There is a functional relationship between the structure of the arch of the foot and the biomechanics of the lower leg. The arch provides an elastic, springy connection between the forefoot and the hind foot so that a majority of the forces incurred during weight bearing on the foot can be dissipated before the force reaches the long bones of the leg and thigh. In pes planus, the head of the talus bone is displaced medially and distal from the navicular bone. As a result, the Plantar calcaneonavicular ligament (spring ligament) and the tendon of the tibialis posterior muscle are stretched to the extent that the individual with pes planus loses the function of the medial longitudinal arch (MLA). If the MLA is a ...
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Lacuna (histology)
In histology, a lacuna is a small space, containing an osteocyte in bone, or chondrocyte in cartilage. Bone The lacunae are situated between the lamellae, and consist of a number of oblong spaces. In an ordinary microscopic section, viewed by transmitted light, they appear as fusiform opaque spots. Each lacuna is occupied during life by a branched cell, termed an osteocyte, bone-cell or bone-corpuscle. Lacunae are connected to one another by small canals called canaliculi. A lacuna never contains more than one osteocyte. Sinuses are an example of lacuna. Cartilage The cartilage cells or chondrocytes are contained in cavities in the matrix, called cartilage lacunae; around these, the matrix is arranged in concentric lines as if it had been formed in successive portions around the cartilage cells. This constitutes the so-called capsule of the space. Each lacuna is generally occupied by a single cell, but during the division of the cells, it may contain two, four, or eight cells. L ...
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James Frederick Brailsford
James Frederick Brailsford MD, FRCP (8 July 1888 – 28 January 1961) was a British radiologist, known as the founder and first president of the British Association of Radiologists and as the co-discoverer of the Morquio (or Morquio-Brailsford) syndrome. He studied with Sir John Robertson, the Medical Officer of Health of Birmingham. In 1923 Brailsford qualified MB, ChB (Birmingham) and was appointed assistant radiologist to Queen's Hospital, Birmingham. In 1928 he received the higher qualification MD (Birmingham). As a radiologist and a demonstrator in living anatomy, he published in 1934 his famous textbook ''The Radiology of Joints and Bones'' and thereby was acknowledged as one of the world's authorities on skeletal diseases. He received PhD Birmingham (1936) and became MRCS, LRCP (1923), MRCP (1935), and FRCP (1941). Awards and honours *1927 — Robert Jones gold medal of the British Orthopaedic Association The British Orthopaedic Association is a professional associat ...
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