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Min System
The Min System is a mechanism composed of three proteins MinC, MinD, and MinE used by ''E. coli'' as a means of properly localizing the septum prior to cell division. Each component participates in generating a dynamic oscillation of FtsZ protein inhibition between the two bacterial poles to precisely specify the mid-zone of the cell, allowing the cell to accurately divide in two. This system is known to function in conjunction with a second negative regulatory system, the nucleoid occlusion system (NO), to ensure proper spatial and temporal regulation of chromosomal segregation and division. History The initial discovery of this family of proteins is attributed to Adler et al. (1967). First identified as ''E. coli'' mutants that could not produce a properly localized septum, resulting in the generation of minicells due to mislocalized cell division occurring near the bacterial poles. This caused miniature vesicles to pinch off, void of essential molecular constituents permitt ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
MinC
The MinC protein is one of three proteins in the Min system encoded by the ''minB'' operon and which is required to generate pole to pole oscillations prior to bacterial cell division as a means of specifying the midzone of the cell. This function is achieved by preventing the formation of the divisome Z-ring around the poles. History When initially discovered in ''E.coli'', MinC was believed to form a stable cap by binding with MinD at the bacterial caps in a stable and static manner, thereby specifying the mid-zone of the cell by lower-concentration or lack of this complex in that region, alleviating inhibition of Z-ring formation. However, Raskin & de Boer applied live-cell imaging with GFP fusion proteins to reveal a dynamic interaction of the Min proteins, demonstrating that MinC and MinD, with the essential help of MinE, actually rapidly oscillate between the two poles in a non-static manner. MinC is found in diverse genera, including Neisseria, Bacillus, and Synechoc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
MinD
The mind is the set of faculties responsible for all mental phenomena. Often the term is also identified with the phenomena themselves. These faculties include thought, imagination, memory, will, and sensation. They are responsible for various mental phenomena, like perception, pain experience, belief, desire, intention, and emotion. Various overlapping classifications of mental phenomena have been proposed. Important distinctions group them according to whether they are ''sensory'', ''propositional'', ''intentional'', ''conscious'', or ''occurrent''. Minds were traditionally understood as substances but it is more common in the contemporary perspective to conceive them as properties or capacities possessed by humans and higher animals. Various competing definitions of the exact nature of the mind or mentality have been proposed. ''Epistemic definitions'' focus on the privileged epistemic access the subject has to these states. ''Consciousness-based approaches'' give primacy to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
MinE
Mine, mines, miners or mining may refer to: Extraction or digging * Miner, a person engaged in mining or digging *Mining, extraction of mineral resources from the ground through a mine Grammar *Mine, a first-person English possessive pronoun Military * Anti-tank mine, a land mine made for use against armored vehicles * Antipersonnel mine, a land mine targeting people walking around, either with explosives or poison gas * Bangalore mine, colloquial name for the Bangalore torpedo, a man-portable explosive device for clearing a path through wire obstacles and land mines * Cluster bomb, an aerial bomb which releases many small submunitions, which often act as mines * Land mine, explosive mines placed under or on the ground * Mining (military), digging under a fortified military position to penetrate its defenses * Naval mine, or sea mine, a mine at sea, either floating or on the sea bed, often dropped via parachute from aircraft, or otherwise lain by surface ships or submarines ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Septum
In biology, a septum (Latin for ''something that encloses''; plural septa) is a wall, dividing a cavity or structure into smaller ones. A cavity or structure divided in this way may be referred to as septate. Examples Human anatomy * Interatrial septum, the wall of tissue that is a sectional part of the left and right atria of the heart * Interventricular septum, the wall separating the left and right ventricles of the heart * Lingual septum, a vertical layer of fibrous tissue that separates the halves of the tongue. *Nasal septum: the cartilage wall separating the nostrils of the nose * Alveolar septum: the thin wall which separates the alveoli from each other in the lungs * Orbital septum, a palpebral ligament in the upper and lower eyelids * Septum pellucidum or septum lucidum, a thin structure separating two fluid pockets in the brain * Uterine septum, a malformation of the uterus * Vaginal septum, a lateral or transverse partition inside the vagina * Intermuscular sep ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cell Division
Cell division is the process by which a parent cell (biology), cell divides into two daughter cells. Cell division usually occurs as part of a larger cell cycle in which the cell grows and replicates its chromosome(s) before dividing. In eukaryotes, there are two distinct types of cell division: a vegetative division (mitosis), producing daughter cells genetically identical to the parent cell, and a cell division that produces Haploidisation, haploid gametes for sexual reproduction (meiosis), reducing the number of chromosomes from two of each type in the diploid parent cell to one of each type in the daughter cells. In cell biology, mitosis (Help:IPA/English, /maɪˈtoʊsɪs/) is a part of the cell cycle, in which, replicated chromosomes are separated into two new Cell nucleus, nuclei. Cell division gives rise to genetically identical cells in which the total number of chromosomes is maintained. In general, mitosis (division of the nucleus) is preceded by the S stage of interph ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
FtsZ
FtsZ is a protein encoded by the ''ftsZ'' gene that assembles into a ring at the future site of bacterial cell division (also called the Z ring). FtsZ is a prokaryotic homologue of the eukaryotic protein tubulin. The initials FtsZ mean "Filamenting temperature-sensitive mutant Z." The hypothesis was that cell division mutants of '' E. coli'' would grow as filaments due to the inability of the daughter cells to separate from one another. FtsZ is found in almost all bacteria, many archaea, all chloroplasts and some mitochondria, where it is essential for cell division. FtsZ assembles the cytoskeletal scaffold of the Z ring that, along with additional proteins, constricts to divide the cell in two. History In the 1960s scientists screened for temperature sensitive mutations that blocked cell division at 42 °C. The mutant cells divided normally at 30°, but failed to divide at 42°. Continued growth without division produced long filamentous cells (Filamenting temperature s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Minicell
In bacteriology, minicells are bacterial cells that are smaller than usual. The first minicells reported were from a strain of ''Escherichia coli'' that had a mutation in the Min System that lead to mis-localization of the septum during cell division and the production of cells of random sizes. Generation of minicells The first report of minicells in the scientific literature dates to 1930., but the first use of the name "minicell" dates to 1967 Minicells of a variety of gram negative and gram positive bacteria, including ''Escherichia coli'' and ''Salmonella enterica'', have been reported, but in principle, minicells could be generated for any bacterial species that can be genetically edited. Minicells can not reproduce because they do not contain a full copy of the genome. Normal role of minicells in bacteriology Scientists hypothesize that minicells are produced by normal bacteria in times of stress so that damaged areas of the cell can be expelled. Applications of m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Min Spirals
Min or MIN may refer to: Places * Fujian, also called Mǐn, a province of China ** Min Kingdom (909–945), a state in Fujian * Min County, a county of Dingxi, Gansu province, China * Min River (Fujian) * Min River (Sichuan) * Mineola (Amtrak station), station code MIN People Personal names * Min (Korean name), Korean surname and given names * Min (surname) (闵/閔), a Chinese surname Individuals with the name * Min (Vietnamese singer) (born 1988) * Min (Korean singer) (born 1991), South Korean singer, songwriter and actress Lee Min-young * Min (treasurer), ancient Egyptian official * Min, Marquis of Jin (died 678 BC), Chinese monarch * Empress Myeongseong (1851–1895), informally Queen Min, empress of Joseon * Menes or Min (a spelling variant no longer accepted), an early Egyptian pharaoh * Min Hogg (born 1939), British journalist and magazine editor * Min, a character from ''Barney & Friends'' played by Pia Hamilton from 1992 to 1995 * Min Hael Cassidy, a character from th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Escherichia Coli
''Escherichia coli'' (),Wells, J. C. (2000) Longman Pronunciation Dictionary. Harlow ngland Pearson Education Ltd. also known as ''E. coli'' (), is a Gram-negative, facultative anaerobic, rod-shaped, coliform bacterium of the genus ''Escherichia'' that is commonly found in the lower intestine of warm-blooded organisms. Most ''E. coli'' strains are harmless, but some serotypes ( EPEC, ETEC etc.) can cause serious food poisoning in their hosts, and are occasionally responsible for food contamination incidents that prompt product recalls. Most strains do not cause disease in humans and are part of the normal microbiota of the gut; such strains are harmless or even beneficial to humans (although these strains tend to be less studied than the pathogenic ones). For example, some strains of ''E. coli'' benefit their hosts by producing vitamin K2 or by preventing the colonization of the intestine by pathogenic bacteria. These mutually beneficial relationships between ''E. col ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genomics
Genomics is an interdisciplinary field of biology focusing on the structure, function, evolution, mapping, and editing of genomes. A genome is an organism's complete set of DNA, including all of its genes as well as its hierarchical, three-dimensional structural configuration. In contrast to genetics, which refers to the study of ''individual'' genes and their roles in inheritance, genomics aims at the collective characterization and quantification of ''all'' of an organism's genes, their interrelations and influence on the organism. Genes may direct the production of proteins with the assistance of enzymes and messenger molecules. In turn, proteins make up body structures such as organs and tissues as well as control chemical reactions and carry signals between cells. Genomics also involves the sequencing and analysis of genomes through uses of high throughput DNA sequencing and bioinformatics to assemble and analyze the function and structure of entire genomes. Advances in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
