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Mendelian Inheritance
Mendelian inheritance (also known as Mendelism) is a type of biological inheritance following the principles originally proposed by Gregor Mendel in 1865 and 1866, re-discovered in 1900 by Hugo de Vries and Carl Correns, and later popularized by William Bateson. These principles were initially controversial. When Mendel's theories were integrated with the Boveri–Sutton chromosome theory of inheritance by Thomas Hunt Morgan in 1915, they became the core of classical genetics. Ronald Fisher combined these ideas with the theory of natural selection in his 1930 book ''The Genetical Theory of Natural Selection'', putting evolution onto a mathematical footing and forming the basis for population genetics within the modern evolutionary synthesis. History The principles of Mendelian inheritance were named for and first derived by Gregor Johann Mendel, a nineteenth-century Moravian monk who formulated his ideas after conducting simple hybridisation experiments with pea plants ...
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Gregor Mendel
Gregor Johann Mendel, OSA (; cs, Řehoř Jan Mendel; 20 July 1822 – 6 January 1884) was a biologist, meteorologist, mathematician, Augustinian friar and abbot of St. Thomas' Abbey in Brünn (''Brno''), Margraviate of Moravia. Mendel was born in a German-speaking family in the Silesian part of the Austrian Empire (today's Czech Republic) and gained posthumous recognition as the founder of the modern science of genetics. Though farmers had known for millennia that crossbreeding of animals and plants could favor certain desirable traits, Mendel's pea plant experiments conducted between 1856 and 1863 established many of the rules of heredity, now referred to as the laws of Mendelian inheritance. Mendel worked with seven characteristics of pea plants: plant height, pod shape and color, seed shape and color, and flower position and color. Taking seed color as an example, Mendel showed that when a true-breeding yellow pea and a true-breeding green pea were cross-bred their ...
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Moravians
Moravians ( cs, Moravané or colloquially , outdated ) are a West Slavic ethnographic group from the Moravia region of the Czech Republic, who speak the Moravian dialects of Czech or Common Czech or a mixed form of both. Along with the Silesians of the Czech Republic, a part of the population to identify ethnically as Moravian has registered in Czech censuses since 1991. The figure has fluctuated and in the 2011 census, 6.01% of the Czech population declared Moravian as their ethnicity. Smaller pockets of people declaring Moravian ethnicity are also native to neighboring Slovakia. Etymology A certain ambiguity in Czech derives from the fact that it distinguishes between (Bohemia proper) and (Czech Republic as a whole), but the corresponding adjective and noun designating an inhabitant and/or a member of a nation can be related to either of them. The adjective and the noun ('Bohemian') carry only the meaning of a "socially unconventional person". History Moravian ...
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Chromosome
A chromosome is a long DNA molecule with part or all of the genetic material of an organism. In most chromosomes the very long thin DNA fibers are coated with packaging proteins; in eukaryotic cells the most important of these proteins are the histones. These proteins, aided by chaperone proteins, bind to and condense the DNA molecule to maintain its integrity. These chromosomes display a complex three-dimensional structure, which plays a significant role in transcriptional regulation. Chromosomes are normally visible under a light microscope only during the metaphase of cell division (where all chromosomes are aligned in the center of the cell in their condensed form). Before this happens, each chromosome is duplicated ( S phase), and both copies are joined by a centromere, resulting either in an X-shaped structure (pictured above), if the centromere is located equatorially, or a two-arm structure, if the centromere is located distally. The joined copies are now c ...
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Heredity
Heredity, also called inheritance or biological inheritance, is the passing on of traits from parents to their offspring; either through asexual reproduction or sexual reproduction, the offspring cells or organisms acquire the genetic information of their parents. Through heredity, variations between individuals can accumulate and cause species to evolve by natural selection. The study of heredity in biology is genetics. Overview In humans, eye color is an example of an inherited characteristic: an individual might inherit the "brown-eye trait" from one of the parents. Inherited traits are controlled by genes and the complete set of genes within an organism's genome is called its genotype. The complete set of observable traits of the structure and behavior of an organism is called its phenotype. These traits arise from the interaction of its genotype with the environment. As a result, many aspects of an organism's phenotype are not inherited. For example, suntanned ski ...
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Allele
An allele (, ; ; modern formation from Greek ἄλλος ''állos'', "other") is a variation of the same sequence of nucleotides at the same place on a long DNA molecule, as described in leading textbooks on genetics and evolution. ::"The chromosomal or genomic location of a gene or any other genetic element is called a locus (plural: loci) and alternative DNA sequences at a locus are called alleles." The simplest alleles are single nucleotide polymorphisms (SNP). but they can also be insertions and deletions of up to several thousand base pairs. Popular definitions of 'allele' typically refer only to different alleles within genes. For example, the ABO blood grouping is controlled by the ABO gene, which has six common alleles (variants). In population genetics, nearly every living human's phenotype for the ABO gene is some combination of just these six alleles. Most alleles observed result in little or no change in the function of the gene product it codes for. Howeve ...
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Genetics
Genetics is the study of genes, genetic variation, and heredity in organisms.Hartl D, Jones E (2005) It is an important branch in biology because heredity is vital to organisms' evolution. Gregor Mendel, a Moravian Augustinian friar working in the 19th century in Brno, was the first to study genetics scientifically. Mendel studied "trait inheritance", patterns in the way traits are handed down from parents to offspring over time. He observed that organisms (pea plants) inherit traits by way of discrete "units of inheritance". This term, still used today, is a somewhat ambiguous definition of what is referred to as a gene. Trait inheritance and molecular inheritance mechanisms of genes are still primary principles of genetics in the 21st century, but modern genetics has expanded to study the function and behavior of genes. Gene structure and function, variation, and distribution are studied within the context of the cell, the organism (e.g. dominance), and within the ...
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Ernst Mayr
Ernst Walter Mayr (; 5 July 1904 – 3 February 2005) was one of the 20th century's leading evolutionary biologists. He was also a renowned taxonomist, tropical explorer, ornithologist, philosopher of biology, and historian of science. His work contributed to the conceptual revolution that led to the modern evolutionary synthesis of Mendelian genetics, systematics, and Darwinian evolution, and to the development of the biological species concept. Although Charles Darwin and others posited that multiple species could evolve from a single common ancestor, the mechanism by which this occurred was not understood, creating the '' species problem''. Ernst Mayr approached the problem with a new definition for species. In his book '' Systematics and the Origin of Species'' (1942) he wrote that a species is not just a group of morphologically similar individuals, but a group that can breed only among themselves, excluding all others. When populations within a species become is ...
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Erich Von Tschermak
Erich Tschermak, Edler von Seysenegg (15 November 1871 – 11 October 1962) was an Austrian agronomist who developed several new disease-resistant crops, including wheat-rye and oat hybrids. He was a son of the Moravia-born mineralogist Gustav Tschermak von Seysenegg. His maternal grandfather was the botanist, Eduard Fenzl, who taught Gregor Mendel botany during his student days in Vienna. He received his doctorate from the University of Halle, Germany, in 1896. Tschermak accepted a teaching position at the University of Agricultural Sciences Vienna in 1901, and became professor there five years later, in 1900. Von Tschermak is one of four men—see also Hugo de Vries, Carl Correns and William Jasper Spillman—who independently rediscovered Gregor Mendel's work on genetics. Von Tschermak published his findings in June, 1900. His works in genetics were largely influenced by his brother Armin von Tschermak-Seysenegg. Decorations and awards * Member Royal Swedish Academy of A ...
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Quantitative Trait Locus
A quantitative trait locus (QTL) is a locus (section of DNA) that correlates with variation of a quantitative trait in the phenotype of a population of organisms. QTLs are mapped by identifying which molecular markers (such as SNPs or AFLPs) correlate with an observed trait. This is often an early step in identifying the actual genes that cause the trait variation. Definition A quantitative trait locus (QTL) is a region of DNA which is associated with a particular phenotypic trait, which varies in degree and which can be attributed to polygenic effects, i.e., the product of two or more genes, and their environment. . These QTLs are often found on different chromosomes. The number of QTLs which explain variation in the phenotypic trait indicates the genetic architecture of a trait. It may indicate that plant height is controlled by many genes of small effect, or by a few genes of large effect. Typically, QTLs underlie continuous traits (those traits which vary continuousl ...
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Complex Traits
Complex traits, also known as quantitative traits, are traits that do not behave according to simple Mendelian inheritance laws. More specifically, their inheritance cannot be explained by the genetic segregation of a single gene. Such traits show a continuous range of variation and are influenced by both environmental and genetic factors. Compared to strictly Mendelian traits, complex traits are far more common, and because they can be hugely polygenic, they are studied using statistical techniques such as QTL mapping rather than classical genetics methods. Examples of complex traits include height, circadian rhythms, enzyme kinetics, and many diseases including diabetes and Parkinson's disease. One major goal of genetic research today is to better understand the molecular mechanisms through which genetic variants act to influence complex traits. History When Mendel’s work on inheritance was rediscovered in 1900, scientists debated whether Mendel’s laws could account for ...
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Blending Inheritance
Blending may refer to: * The process of mixing in process engineering * Mixing paints to achieve a greater range of colors * Blending (alcohol production), a technique to produce alcoholic beverages by mixing different brews * Blending (linguistics), the process of forming a word from two or more letters that represent the sounds of a word * Blending (music), a technique used in instrument playing * Blending (vocal technique), a technique used in vocal warm up * Blending curves, in mathematics * Blending inheritance, a hypothetical model prior to the discovery of genetics * Alpha blending, a transparency technique in computer image generation * Conceptual blending, a general theory of cognition * Gas blending, the filling of diving cylinders with non-air breathing gases such as nitrox, trimix and heliox * Tea blending Tea blending is the act of blending different teas together to produce a final product that differs in flavor from the original tea used. This occurs chiefly ...
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Brno
Brno ( , ; german: Brünn ) is a city in the South Moravian Region of the Czech Republic. Located at the confluence of the Svitava and Svratka rivers, Brno has about 380,000 inhabitants, making it the second-largest city in the Czech Republic after the capital, Prague, and one of the 100 largest cities of the EU. The Brno metropolitan area has almost 700,000 inhabitants. Brno is the former capital city of Moravia and the political and cultural hub of the South Moravian Region. It is the centre of the Czech judiciary, with the seats of the Constitutional Court, the Supreme Court, the Supreme Administrative Court, and the Supreme Public Prosecutor's Office, and a number of state authorities, including the Ombudsman, and the Office for the Protection of Competition. Brno is also an important centre of higher education, with 33 faculties belonging to 13  institutes of higher education and about 89,000 students. Brno Exhibition Centre is among the largest exhibition ...
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