|
Maximilian Von Frey
Maximilian (Max) Ruppert Franz von Frey (16 November 1852 – 25 January 1932) was an Austrian-German physiologist who was born in Salzburg. He received his doctorate from the University of Leipzig in 1877, and subsequently worked at Carl Ludwig's Physiological Institute in Leipzig. Later he was a professor of physiology at the Universities of Würzburg and Zurich. Frey's primary work in Leipzig dealt with the circulatory system, and he is credited with developing an early prototype of a heart-lung machine. He is remembered for his work involving cutaneous sensory mechanoreceptors. During the 1890s, Frey proposed that pain is an independent tactile quality, alongside touch, heat and cold, and that it is associated with stimulation of high-threshold free nerve endings. He described the skin as a mosaic of discrete spots, each sensitive to one or another of these stimuli. He created a unique type of esthesiometer, now referred to as a von Frey hair An esthesiometer (British spelli ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Germany
Germany,, officially the Federal Republic of Germany, is a country in Central Europe. It is the second most populous country in Europe after Russia, and the most populous member state of the European Union. Germany is situated between the Baltic and North seas to the north, and the Alps to the south; it covers an area of , with a population of almost 84 million within its 16 constituent states. Germany borders Denmark to the north, Poland and the Czech Republic to the east, Austria and Switzerland to the south, and France, Luxembourg, Belgium, and the Netherlands to the west. The nation's capital and most populous city is Berlin and its financial centre is Frankfurt; the largest urban area is the Ruhr. Various Germanic tribes have inhabited the northern parts of modern Germany since classical antiquity. A region named Germania was documented before AD 100. In 962, the Kingdom of Germany formed the bulk of the Holy Roman Empire. During the 16th ce ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cutaneous
Skin is the layer of usually soft, flexible outer tissue covering the body of a vertebrate animal, with three main functions: protection, regulation, and sensation. Other animal coverings, such as the arthropod exoskeleton, have different developmental origin, structure and chemical composition. The adjective cutaneous means "of the skin" (from Latin ''cutis'' 'skin'). In mammals, the skin is an organ of the integumentary system made up of multiple layers of ectodermal tissue and guards the underlying muscles, bones, ligaments, and internal organs. Skin of a different nature exists in amphibians, reptiles, and birds. Skin (including cutaneous and subcutaneous tissues) plays crucial roles in formation, structure, and function of extraskeletal apparatus such as horns of bovids (e.g., cattle) and rhinos, cervids' antlers, giraffids' ossicones, armadillos' osteoderm, and os penis/os clitoris. All mammals have some hair on their skin, even marine mammals like whales, dolphins, a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Physicians From Salzburg
A physician (American English), medical practitioner (Commonwealth English), medical doctor, or simply doctor, is a health professional who practices medicine, which is concerned with promoting, maintaining or restoring health through the study, diagnosis, prognosis and treatment of disease, injury, and other physical and mental impairments. Physicians may focus their practice on certain disease categories, types of patients, and methods of treatment—known as specialities—or they may assume responsibility for the provision of continuing and comprehensive medical care to individuals, families, and communities—known as general practice. Medical practice properly requires both a detailed knowledge of the academic disciplines, such as anatomy and physiology, underlying diseases and their treatment—the ''science'' of medicine—and also a decent competence in its applied practice—the art or ''craft'' of medicine. Both the role of the physician and the meaning of t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
German Physiologists
German(s) may refer to: * Germany (of or related to) **Germania (historical use) * Germans, citizens of Germany, people of German ancestry, or native speakers of the German language ** For citizens of Germany, see also German nationality law **Germanic peoples (Roman times) * German language **any of the Germanic languages * German cuisine, traditional foods of Germany People * German (given name) * German (surname) * Germán, a Spanish name Places * German (parish), Isle of Man * German, Albania, or Gërmej * German, Bulgaria * German, Iran * German, North Macedonia * German, New York, U.S. * Agios Germanos, Greece Other uses * German (mythology), a South Slavic mythological being * Germans (band), a Canadian rock band * "German" (song), a 2019 song by No Money Enterprise * ''The German'', a 2008 short film * "The Germans", an episode of ''Fawlty Towers'' * ''The German'', a nickname for Congolese rebel André Kisase Ngandu See also * Germanic (other) * Germa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1932 Deaths
Year 193 ( CXCIII) was a common year starting on Monday (link will display the full calendar) of the Julian calendar. At the time, it was known as the Year of the Consulship of Sosius and Ericius (or, less frequently, year 946 ''Ab urbe condita''). The denomination 193 for this year has been used since the early medieval period, when the Anno Domini calendar era became the prevalent method in Europe for naming years. Events By place Roman Empire * January 1 – Year of the Five Emperors: The Roman Senate chooses Publius Helvius Pertinax, against his will, to succeed the late Commodus as Emperor. Pertinax is forced to reorganize the handling of finances, which were wrecked under Commodus, to reestablish discipline in the Roman army, and to suspend the food programs established by Trajan, provoking the ire of the Praetorian Guard. * March 28 – Pertinax is assassinated by members of the Praetorian Guard, who storm the imperial palace. The Empire is auctioned off ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1852 Births
Year 185 ( CLXXXV) was a common year starting on Friday (link will display the full calendar) of the Julian calendar. At the time, it was known as the Year of the Consulship of Lascivius and Atilius (or, less frequently, year 938 '' Ab urbe condita''). The denomination 185 for this year has been used since the early medieval period, when the Anno Domini calendar era became the prevalent method in Europe for naming years. Events By place Roman Empire * Nobles of Britain demand that Emperor Commodus rescind all power given to Tigidius Perennis, who is eventually executed. * Publius Helvius Pertinax is made governor of Britain and quells a mutiny of the British Roman legions who wanted him to become emperor. The disgruntled usurpers go on to attempt to assassinate the governor. * Tigidius Perennis, his family and many others are executed for conspiring against Commodus. * Commodus drains Rome's treasury to put on gladiatorial spectacles and confiscates property to su ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Monofilament Fishing Line
Monofilament fishing line (shortened to just mono) is fishing line made from a single fiber of plastic material, as opposed to multifilament or braided fishing lines constructed from multiple strands of fibers. Most fishing lines are now nylon monofilament because they are cheap to produce and can be produced in a range of diameters which have different tensile strengths (called "tests" after the process of tensile testing, or possibly as a portmanteau of "tensile" and "strength"). Monofilament line is also manufactured in different colors, such as clear, white, green, blue, red, and fluorescent. Monofilament is made by melting and mixing polymers and then extruding the mixture through tiny holes, forming strands of line, which is then spun into spools of various thicknesses. The extrusion process controls not only the thickness of the line but its test as well. History DuPont made public in 1938 that their company had invented nylon. [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Von Frey Hair
An esthesiometer (British spelling aesthesiometer) is a device for measuring the tactile sensitivity of the skin (or mouth, or eye, etc.). The measure of the degree of tactile sensitivity is called aesthesiometry. The device was invented by Edward Henry Sieveking. There are different types of aesthesiometers depending on their particular function. Two-point discrimination The simplest is a manual tool with adjustable points similar to a caliper. It can determine how short a distance between two impressions on the skin can be distinguished. To differentiate between two points and one point of equal area (the sum of the areas of the two points equals the area of the third point), Dr. Sidney Weinstein created the three-point esthesiometer. A scale on the instrument gives readings in millimeter gradients. Monofilaments Another type of manual aesthesiometer is used to test lower thresholds of touch or pain. The tool uses nylon monofilaments with varying calibrated diameters. The for ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Esthesiometer
An esthesiometer (British spelling aesthesiometer) is a device for measuring the tactile sensitivity of the skin (or mouth, or eye, etc.). The measure of the degree of tactile sensitivity is called aesthesiometry. The device was invented by Edward Henry Sieveking. There are different types of aesthesiometers depending on their particular function. Two-point discrimination The simplest is a manual tool with adjustable points similar to a caliper. It can determine how short a distance between two impressions on the skin can be distinguished. To differentiate between two points and one point of equal area (the sum of the areas of the two points equals the area of the third point), Dr. Sidney Weinstein created the three-point esthesiometer. A scale on the instrument gives readings in millimeter gradients. Monofilaments Another type of manual aesthesiometer is used to test lower thresholds of touch or pain. The tool uses nylon monofilaments with varying calibrated diameters. The for ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Free Nerve Ending
A free nerve ending (FNE) or bare nerve ending, is an unspecialized, afferent nerve fiber sending its signal to a sensory neuron. ''Afferent'' in this case means bringing information from the body's periphery toward the brain. They function as cutaneous nociceptors and are essentially used by vertebrates to detect noxious stimuli that often result in pain. Structure Free nerve endings are unencapsulated and have no complex sensory structures. They are the most common type of nerve ending, and are most frequently found in the skin. They penetrate the dermis and end in the stratum granulosum. FNEs infiltrate the middle layers of the dermis and surround hair follicles. Types Free nerve endings have different rates of adaptation, stimulus modalities, and fiber types. Rate of adaptation Different types of FNE can be rapidly adapting, intermediate adapting, or slowly adapting. A delta type II fibers are fast-adapting while A delta type I and C fibers are slowly adapting.Rolf-Detlef ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mechanoreceptor
A mechanoreceptor, also called mechanoceptor, is a sensory receptor that responds to mechanical pressure or distortion. Mechanoreceptors are innervated by sensory neurons that convert mechanical pressure into electrical signals that, in animals, are sent to the central nervous system. Vertebrate mechanoreceptors Cutaneous mechanoreceptors Cutaneous mechanoreceptors respond to mechanical stimuli that result from physical interaction, including pressure and vibration. They are located in the skin, like other cutaneous receptors. They are all innervated by Aβ fibers, except the mechanorecepting free nerve endings, which are innervated by Aδ fibers. Cutaneous mechanoreceptors can be categorized by what kind of sensation they perceive, by the rate of adaptation, and by morphology. Furthermore, each has a different receptive field. By sensation *The Slowly Adapting type 1 (SA1) mechanoreceptor, with the Merkel corpuscle end-organ (also known as Merkel discs) detect sustained p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
United States
The United States of America (U.S.A. or USA), commonly known as the United States (U.S. or US) or America, is a country primarily located in North America. It consists of 50 states, a federal district, five major unincorporated territories, nine Minor Outlying Islands, and 326 Indian reservations. The United States is also in free association with three Pacific Island sovereign states: the Federated States of Micronesia, the Marshall Islands, and the Republic of Palau. It is the world's third-largest country by both land and total area. It shares land borders with Canada to its north and with Mexico to its south and has maritime borders with the Bahamas, Cuba, Russia, and other nations. With a population of over 333 million, it is the most populous country in the Americas and the third most populous in the world. The national capital of the United States is Washington, D.C. and its most populous city and principal financial center is New York City. Paleo-Americ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
