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Maurice Nicolle
Maurice Nicolle (1 March 1862 – 20 August 1932) was a French physician and microbiologist born in Rouen. He was the brother of biologist Charles Nicolle (1866–1936). He studied medicine in Rouen and Paris, becoming an interne to the hospitals of Paris in 1885. In 1887 he continued his internship under histologist Albert von Kölliker (1817–1905) at the University of Würzburg. In 1890 he supported his doctorate with a thesis on a study of diseases of the myocardium, titled ''Contribution à l'étude des affections du myocarde: les grandes scléroses cardiaques''. Afterwards he took courses in microbiology at the Pasteur Institute. From 1893 he studied biological staining techniques with Victor Morax (1866–1935), publishing two papers on the staining properties of ammoniated ruthenium oxychloride with Jean Cantacuzène (1863–1934). In 1893 he succeeded Waldemar Haffkine (1860–1930) as an instructor of microbiology at the Pasteur Institute, shortly afterwards bein ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Maurice Nicolle
Maurice Nicolle (1 March 1862 – 20 August 1932) was a French physician and microbiologist born in Rouen. He was the brother of biologist Charles Nicolle (1866–1936). He studied medicine in Rouen and Paris, becoming an interne to the hospitals of Paris in 1885. In 1887 he continued his internship under histologist Albert von Kölliker (1817–1905) at the University of Würzburg. In 1890 he supported his doctorate with a thesis on a study of diseases of the myocardium, titled ''Contribution à l'étude des affections du myocarde: les grandes scléroses cardiaques''. Afterwards he took courses in microbiology at the Pasteur Institute. From 1893 he studied biological staining techniques with Victor Morax (1866–1935), publishing two papers on the staining properties of ammoniated ruthenium oxychloride with Jean Cantacuzène (1863–1934). In 1893 he succeeded Waldemar Haffkine (1860–1930) as an instructor of microbiology at the Pasteur Institute, shortly afterwards bein ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rinderpest
Rinderpest (also cattle plague or steppe murrain) was an infectious viral disease of cattle, domestic buffalo, and many other species of even-toed ungulates, including gaurs, buffaloes, large antelope, deer, giraffes, wildebeests, and warthogs. The disease was characterized by fever, oral erosions, diarrhea, lymphoid necrosis, and high mortality. Death rates during outbreaks were usually extremely high, approaching 100% in immunologically naïve populations. Rinderpest was mainly transmitted by direct contact and by drinking contaminated water, although it could also be transmitted by air. After a global eradication campaign starting in the mid-20th century, the last confirmed case of rinderpest was diagnosed in 2001. On 14 October 2010, the United Nations Food and Agriculture Organization (FAO) announced that field activities in the decades-long, worldwide campaign to eradicate the disease were ending, paving the way for a formal declaration in June 2011 of the global eradi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Trypanocidal Agent
A trypanocidal agent is an antiprotozoal agent that acts upon Trypanosoma, trypanosome parasites. Examples include: * Aminoquinuride * benzonidazole * blasticidin S * DAPI * diminazene * diminazene aceturate * eflornithine * ethidium * isometamidium chloride * lonidamine * melaminylthioarsenate * melarsoprol * nifurtimox * pentamidine * posaconazole * puromycin * quinapyramine * salicylhydroxamic acid * suramin * tetraphenylporphine sulfonate Resistance 17 or 18 African countries had confirmed trypanocide resistance, resistant parasite populations, and that was up to 21. Multiple drug resistance, Multiply resistant populations are an increasing problem in the Adamawa Region of Cameroon and south east Mali. The Gibe River Valley in southwest Ethiopia showed universal resistance (in ''Trypanosoma congolense, T. congolense'' isolated from Boran cattle) between July 1989 and February 1993. This likely indicates a permanent loss of function in this area for the tested trypanocides, Dim ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bayer Pharmaceutical
Bayer AG (, commonly pronounced ; ) is a German multinational pharmaceutical and biotechnology company and one of the largest pharmaceutical companies in the world. Headquartered in Leverkusen, Bayer's areas of business include pharmaceuticals; consumer healthcare products, agricultural chemicals, seeds and biotechnology products. The company is a component of the Euro Stoxx 50 stock market index. Bayer was founded in 1863 in Barmen as a partnership between dye salesman Friedrich Bayer and dyer Friedrich Weskott. As was common in this era, the company was established as a dyestuffs producer. The versatility of aniline chemistry led Bayer to expand their business into other areas, and in 1899 Bayer launched the compound acetylsalicylic acid under the trademarked name Aspirin. In 1904 Bayer received a trademark for the "Bayer Cross" logo, which was subsequently stamped onto each aspirin tablet, creating an iconic product that is still sold by Bayer. Other commonly known pro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Felix Mesnil
Felix may refer to: * Felix (name), people and fictional characters with the name Places * Arabia Felix is the ancient Latin name of Yemen * Felix, Spain, a municipality of the province Almería, in the autonomous community of Andalusia, Spain * St. Felix, Prince Edward Island, a rural community in Prince County, Prince Edward Island, Canada. * Felix, Ontario, an unincorporated place and railway point in Northeastern Ontario, Canada * St. Felix, South Tyrol, a village in South Tyrol, in northern Italy. * Felix, California, an unincorporated community in Calaveras County Music * Felix (band), a British band * Felix (musician), British DJ * Félix Award, a Quebec music award named after Félix Leclerc Business * Felix (pet food), a brand of cat food sold in most European countries * AB Felix, a Swedish food company * Felix Bus Services of Derbyshire, England * Felix Airways, an airline based in Yemen Science and technology * Apache Felix, an open source OSGi framewo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Zoologist
Zoology ()The pronunciation of zoology as is usually regarded as nonstandard, though it is not uncommon. is the branch of biology that studies the animal kingdom, including the structure, embryology, evolution, classification, habits, and distribution of all animals, both living and extinct, and how they interact with their ecosystems. The term is derived from Ancient Greek , ('animal'), and , ('knowledge', 'study'). Although humans have always been interested in the natural history of the animals they saw around them, and made use of this knowledge to domesticate certain species, the formal study of zoology can be said to have originated with Aristotle. He viewed animals as living organisms, studied their structure and development, and considered their adaptations to their surroundings and the function of their parts. The Greek physician Galen studied human anatomy and was one of the greatest surgeons of the ancient world, but after the fall of the Western Roman Empire an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Guinea Pigs
The guinea pig or domestic guinea pig (''Cavia porcellus''), also known as the cavy or domestic cavy (), is a species of rodent belonging to the genus '' Cavia'' in the family Caviidae. Breeders tend to use the word ''cavy'' to describe the animal, while in scientific and laboratory contexts, it is far more commonly referred to by the common name ''guinea pig''. Despite their common name, guinea pigs are not native to Guinea, nor are they closely related biologically to pigs, and the origin of the name is still unclear. They originated in the Andes of South America. Studies based on biochemistry and hybridization suggest they are domesticated animals that do not exist naturally in the wild, descendants of a closely related cavy species such as '' C. tschudii''. They were originally domesticated as livestock for a source of meat, and are still consumed in some parts of the world. In Western society, the guinea pig has enjoyed widespread popularity as a pet since its introduc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Burkholderia Mallei
''Burkholderia mallei'' is a Gram-negative, bipolar, aerobic bacterium, a human and animal pathogen of genus ''Burkholderia'' causing glanders; the Latin name of this disease (''malleus'') gave its name to the species causing it. It is closely related to '' B. pseudomallei,'' and by multilocus sequence typing it is a subspecies of ''B. pseudomallei.'' ''B. mallei'' evolved from ''B. pseudomallei'' by selective reduction and deletions from the ''B. pseudomallei'' genome. Unlike ''B. pseudomallei'' and other genus members, ''B. mallei'' is nonmotile; its shape is coccobacillary measuring some 1.5–3.0 μm in length and 0.5–1.0 μm in diameter with rounded ends. Discovery and early history Wilhelm Schütz and Friedrich Löffler first isolated ''B. mallei'' in 1882. It was isolated from an infected liver and spleen of a horse. This bacterium is also one of the first to be identified containing a type VI secretion system which is important for it ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Antigens
In immunology, an antigen (Ag) is a molecule or molecular structure or any foreign particulate matter or a pollen grain that can bind to a specific antibody or T-cell receptor. The presence of antigens in the body may trigger an immune response. The term ''antigen'' originally referred to a substance that is an antibody generator. Antigens can be proteins, peptides (amino acid chains), polysaccharides (chains of monosaccharides/simple sugars), lipids, or nucleic acids. Antigens are recognized by antigen receptors, including antibodies and T-cell receptors. Diverse antigen receptors are made by cells of the immune system so that each cell has a specificity for a single antigen. Upon exposure to an antigen, only the lymphocytes that recognize that antigen are activated and expanded, a process known as clonal selection. In most cases, an antibody can only react to and bind one specific antigen; in some instances, however, antibodies may cross-react and bind more than one antigen. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Antibodies
An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein used by the immune system to identify and neutralize foreign objects such as pathogenic bacteria and viruses. The antibody recognizes a unique molecule of the pathogen, called an antigen. Each tip of the "Y" of an antibody contains a paratope (analogous to a lock) that is specific for one particular epitope (analogous to a key) on an antigen, allowing these two structures to bind together with precision. Using this binding mechanism, an antibody can ''tag'' a microbe or an infected cell for attack by other parts of the immune system, or can neutralize it directly (for example, by blocking a part of a virus that is essential for its invasion). To allow the immune system to recognize millions of different antigens, the antigen-binding sites at both tips of the antibody come in an equally wide variety. In contrast, the remainder of the antibody is relatively constant. It only occurs in a few va ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Immunity (medical)
In biology, immunity is the capability of multicellular organisms to resist harmful microorganisms. Immunity involves both specific and nonspecific components. The nonspecific components act as barriers or eliminators of a wide range of pathogens irrespective of their antigenic make-up. Other components of the immune system adapt themselves to each new disease encountered and can generate pathogen-specific immunity. Immunity is a complex biological system that can recognize and tolerate whatever belongs to the self, and to recognize and reject what is foreign (non-self). Innate and adaptive Innate Immunity First off, the immune system is a system in the body of animals that enables animals to avoid or limit many infections caused by pathogens. Pathogens are disease causing agents, causing a wide range of illnesses. As for Diseases it's when structure of an organism is negatively affected other than external injury. Both diseases and pathogens affect the immune system causing ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hypersensitivity
Hypersensitivity (also called hypersensitivity reaction or intolerance) refers to undesirable reactions produced by the normal immune system, including allergies and autoimmunity. They are usually referred to as an over-reaction of the immune system and these reactions may be damaging and uncomfortable. This is an immunologic term and is not to be confused with the psychiatric term of being hypersensitive which implies to an individual who may be overly sensitive to physical (i.e. sound, touch, light, etc.) and/or emotional stimuli. Although there is a relation between the two – studies have shown that those individuals that have ADHD (a psychiatric disorder) are more likely to have hypersensitivity reactions such as allergies, asthma, eczema than those who do not have ADHD. Hypersensitivity reactions can be classified into four types. Type I: IgE mediated immediate reaction Type II: Antibody-mediated reaction (IgG or IgM antibodies) Type III: Immune complex-mediated r ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
