Mapp Biopharmaceutical
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Mapp Biopharmaceutical
Mapp Biopharmaceutical is an American pharmaceutical company founded in 2003 by Larry Zeitlin and Kevin Whaley. Mapp Biopharmaceutical is based in San Diego, California. It is responsible for the research and development of ZMapp, a drug which is still under development and comprises three humanized monoclonal antibodies used as a treatment for Ebola virus disease. The drug was first tested in humans during the 2014 West Africa Ebola virus outbreak. The ZMapp drug is a result of the collaboration between Mapp Biopharmaceutical, LeafBio (the commercial arm of Mapp Biopharmaceutical), Defyrus Inc. (Toronto), the U.S. government, and the Public Health Agency of Canada. The antibody work came out of research projects funded by Defense Advanced Research Projects Agency (DARPA) more than a decade ago, and years of funding by the Public Health Agency of Canada. Helen Branswell for The Canadian Press. Aug. 5, 201Experimental Ebola drug based on research discoveries from Canada's nationa ...
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Biopharmaceutical
A biopharmaceutical, also known as a biological medical product, or biologic, is any pharmaceutical drug product manufactured in, extracted from, or semisynthesized from biological sources. Different from totally synthesized pharmaceuticals, they include vaccines, whole blood, blood components, allergenics, somatic cells, gene therapies, tissues, recombinant therapeutic protein, and living medicines used in cell therapy. Biologics can be composed of sugars, proteins, nucleic acids, or complex combinations of these substances, or may be living cells or tissues. They (or their precursors or components) are isolated from living sources—human, animal, plant, fungal, or microbial. They can be used in both human and animal medicine. Terminology surrounding biopharmaceuticals varies between groups and entities, with different terms referring to different subsets of therapeutics within the general biopharmaceutical category. Some regulatory agencies use the terms ''biological ...
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Helen Branswell
Helen Branswell is a Canadian infectious diseases and global health reporter at Stat News. Branswell spent fifteen years as a medical reporter at The Canadian Press, where she led coverage of the Ebola, Zika, SARS and swine flu pandemics. She joined Stat News at its founding 2015, leading the website's coverage of the ongoing COVID-19 pandemic. Early life and education Branswell is from Canada and has family in Ottawa. In 1978, Branswell received a B.A. in English literature the St. Thomas University in New Brunswick, Canada. When asked how she wound up in journalism she replied: "I fell into journalism, I was not somebody who had worked at a high school newspaper or college newspaper or anything. I just didn’t know what to do after getting a Bachelor of Arts degree in English Literature. And somebody said, “What can you do?” And I said, “I think I can write.” And so, I started freelancing for the local paper in the small town I lived in at the time in Eastern Canada ...
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Companies Based In San Diego
A company, abbreviated as co., is a legal entity representing an association of people, whether natural, legal or a mixture of both, with a specific objective. Company members share a common purpose and unite to achieve specific, declared goals. Companies take various forms, such as: * voluntary associations, which may include nonprofit organizations * business entities, whose aim is generating profit * financial entities and banks * programs or educational institutions A company can be created as a legal person so that the company itself has limited liability as members perform or fail to discharge their duty according to the publicly declared incorporation, or published policy. When a company closes, it may need to be liquidated to avoid further legal obligations. Companies may associate and collectively register themselves as new companies; the resulting entities are often known as corporate groups. Meanings and definitions A company can be defined as an "artificial per ...
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Winston-Salem Journal
The ''Winston-Salem Journal'' is an American, English language daily newspaper primarily serving Winston-Salem, North Carolina, Winston-Salem and Forsyth County, North Carolina. It also covers Northwestern North Carolina. The paper is owned by Lee Enterprises. ''The Journal'' was founded in 1897. Overview ''The Journal'' is primarily distributed through Forsyth County and the county seat of Winston-Salem. However, the paper also is distributed in Alleghany County, North Carolina, Alleghany County, Ashe County, North Carolina, Ashe County, Davidson County, North Carolina, Davidson County, Davie County, North Carolina, Davie County, Stokes County, North Carolina, Stokes County, Surry County, North Carolina, Surry County, Wilkes County, North Carolina, Wilkes County, Watauga County, North Carolina, Watauga County, and Yadkin County, North Carolina, Yadkin County. The newspaper has an online presence called ''JournalNow''. ''The Journals television partner is WGHP of High Point, ...
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Popular Science
''Popular Science'' (also known as ''PopSci'') is an American digital magazine carrying popular science content, which refers to articles for the general reader on science and technology subjects. ''Popular Science'' has won over 58 awards, including the American Society of Magazine Editors awards for its journalistic excellence in 2003 (for General Excellence), 2004 (for Best Magazine Section), and 2019 (for Single-Topic Issue). With roots beginning in 1872, ''Popular Science'' has been translated into over 30 languages and is distributed to at least 45 countries. Early history ''The Popular Science Monthly'', as the publication was originally called, was founded in May 1872 by Edward L. Youmans to disseminate scientific knowledge to the educated layman. Youmans had previously worked as an editor for the weekly ''Appleton's Journal'' and persuaded them to publish his new journal. Early issues were mostly reprints of English periodicals. The journal became an outlet for writings ...
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Reynolds American
Reynolds American, Inc. is an American tobacco company which is a subsidiary of British American Tobacco and is the second-largest tobacco company in the United States. Its holdings include R. J. Reynolds Tobacco Company, American Snuff Company (formerly Conwood Company), Santa Fe Natural Tobacco Company, and Niconovum AB. Reynolds American's subsidiaries manufacture and market a variety of tobacco products, including cigarettes ( Newport, Camel, Pall Mall, Kent, Doral, Misty, Capri, and Natural American Spirit brands), electronic cigarettes (Vuse brand), and moist snuff (Grizzly and Kodiak brands). In 2010, Reynolds American's operating companies sold about 28% of all cigarettes sold in the U.S. In July 2014, Reynolds American announced the purchase of Lorillard Tobacco Company in a deal valued at $27 billion. In January 2017, Reynolds American agreed to be purchased by British American Tobacco for $49.4 billion. History Reynolds American was formed in January 2004 and began ...
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Pharming (genetics)
Pharming, a portmanteau of "farming" and "pharmaceutical", refers to the use of genetic engineering to insert genes that code for useful pharmaceuticals into host animals or plants that would otherwise not express those genes, thus creating a genetically modified organism (GMO). Pharming is also known as molecular farming, molecular pharming or biopharming. The products of pharming are recombinant proteins or their metabolic products. Recombinant proteins are most commonly produced using bacteria or yeast in a bioreactor, but pharming offers the advantage to the producer that it does not require expensive infrastructure, and production capacity can be quickly scaled to meet demand, at greatly reduced cost. History The first recombinant plant-derived protein (PDP) was human serum albumin, initially produced in 1990 in transgenic tobacco and potato plants. Open field growing trials of these crops began in the United States in 1992 and have taken place every year since. While th ...
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Bioproduction
Bioproduction is the production of biologics-based therapeutic drugs including protein-based therapeutics, vaccines, gene therapies as well as cell therapies; drugs so complex they can only be made in living systems or indeed are a living system (cell therapies). In practice, ‘bioproduction’ has become loosely synonymous with ‘bioprocessing’ as a way to describe the manufacturing process using, cell culture, chromatography, formulation and related analytical testing for large molecule drugs, vaccines and cellular therapies. Many combinations of reactor types and culture modes are now available for use in bioproduction: e.g., pharming, rocking wave-agitated bag batch, stirred-tank or air-lift fed-batch, and hollow-fiber or spin-filter perfusion. No single production format is inherently superior; that determination depends on many manufacturing capabilities, requirements, and goals.Whitford, William G., {{cite web , url=http://www.iclickmedia.com/bioprocessors/4_4_Whitfor ...
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Nicotiana Benthamiana
''Nicotiana benthamiana'', colloquially known as benth or benthi, is a species of ''Nicotiana'' indigenous to Australia. It is a close relative of tobacco. A synonym for this species is ''Nicotiana suaveolens'' var. ''cordifolia'', a description given by George Bentham in ''Flora Australiensis'' in 1868. This was transferred to ''Nicotiana benthamiana'' by Karel Domin in ''Bibliotheca Botanica'' (1929), honoring the original author in the specific epithet. History The plant was used by people of Australia as a stimulant, containing nicotine and other alkaloids, before the introduction of commercial tobacco ('' N. tabacum'' and '' N. rustica''). Indigenous names for it include ''tjuntiwari'' and ''muntju''. It was first collected on the north coast of Australia by Benjamin Bynoe on a voyage of in 1837. Description The herbaceous plant is found amongst rocks on hills and cliffs throughout the northern regions of Australia. Variable in height and habit, the species may be er ...
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DARPA
The Defense Advanced Research Projects Agency (DARPA) is a research and development agency of the United States Department of Defense responsible for the development of emerging technologies for use by the military. Originally known as the Advanced Research Projects Agency (ARPA), the agency was created on February 7, 1958, by President Dwight D. Eisenhower in response to the Soviet Union, Soviet launching of Sputnik 1 in 1957. By collaborating with academia, industry, and government partners, DARPA formulates and executes research and development projects to expand the frontiers of technology and science, often beyond immediate U.S. military requirements.Dwight D. Eisenhower and Science & Technology, (2008). Dwight D. Eisenhower Memorial CommissionSource ''The Economist'' has called DARPA the agency "that shaped the modern world," and pointed out that "Moderna COVID-19 vaccine, Moderna's COVID-19 vaccine sits alongside weather satellites, Global Positioning System, GPS, Unmann ...
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Pharmaceutical Industry
The pharmaceutical industry discovers, develops, produces, and markets drugs or pharmaceutical drugs for use as medications to be administered to patients (or self-administered), with the aim to cure them, vaccinate them, or alleviate symptoms. Pharmaceutical companies may deal in generic or brand medications and medical devices. They are subject to a variety of laws and regulations that govern the patenting, testing, safety, efficacy using drug testing and marketing of drugs. The global pharmaceuticals market produced treatments worth $1,228.45 billion in 2020 and showed a compound annual growth rate (CAGR) of 1.8%. History Mid-1800s – 1945: From botanicals to the first synthetic drugs The modern era of pharmaceutical industry began with local apothecaries that expanded from their traditional role of distributing botanical drugs such as morphine and quinine to wholesale manufacture in the mid-1800s, and from discoveries resulting from applied research. Intentional drug ...
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Public Health Agency Of Canada
The Public Health Agency of Canada (PHAC; french: Agence de la santé publique du Canada, ASPC) is an agency of the Government of Canada that is responsible for public health, emergency preparedness and response, and infectious and chronic disease control and prevention. History The PHAC was formed because of a series of official inquiries about the SARS crisis in Canada which was particularly severe. For example, the province of Ontario inquiry and the National Advisory Committee on SARS and Public Health both recommended that a new organisation be formed. It was so instantiated, by Order in Council in 2004 under the Minister of State for Public Health (Canada) of the Martin government and subsequently by legislation that came into force on December 15, 2006 under the Harper government. It is part of the federal government's Health Portfolio (along with Health Canada, the Canadian Institutes of Health Research, and other organizations). At the time of its creation in 2004, mos ...
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